Search results for "ITC"

showing 10 items of 898 documents

Outcome of opioid switching 4 weeks after discharge from a palliative care unit.

2011

Despite the favorable effects reported with opioid switching performed in a specialized unit in the short term, data on long-term basis are poor, particularly after discharging patients home or in other settings.The aim of this prospective study was to evaluate the long-term outcome of patients who were switched in an acute palliative care unit at a high volume of opioid switching. A consecutive sample of patients who underwent opioid substitution during admission in an acute palliative care unit were assessed for a period of 1 year. Patients were followed-up for 4 weeks after being discharged. Patients were contacted by phone or visited at the outpatient clinic 4 weeks after discharge. Epi…

Malemedicine.medical_specialtyPalliative carepalliative care unitPainSettore MED/42 - Igiene Generale E ApplicataCONSECUTIVE SAMPLEopioid switchingEpidemiologymedicineHumansOutpatient clinicProspective cohort studyAgedRetrospective StudiesDrug Substitutionbusiness.industryPalliative Careopioid switching; palliative care unit; epidemiologic studyGeneral MedicineMiddle AgedAfter dischargeAnalgesics OpioidOpioidAnesthesiaepidemiologic studyFemalebusinessCancer painFollow-Up Studiesmedicine.drug
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Effects of 10 weeks of military training on neuromuscular function in non-overreached and overreached conscripts

2018

The purpose of the study was to examine how military training influences neuromuscular function in non-overreached and overreached conscripts. A total of 24 male conscripts participated in the study (8 weeks basic training + 2 weeks specialized training). All measurements were conducted during weeks 1, 5, 8 and 10. After the training period, non-overreached (NOR, n = 16) and overreached (OR, n = 8) groups were compared. Isometric maximal forces (bench press, elbow flexion and knee extension), single twitch (plantar flexors), H-reflex, M-wave (Hmax/Mmax) and V-wave (V/Mmax) (soleus) were measured. In knee extension, force production increased in NOR by 22.5 ± 20.5% (p  0.01) between weeks 1 …

Malemedicine.medical_specialtyTime FactorsAdolescentmuscleBiophysicsNeuroscience (miscellaneous)lihaksetsotilaskoulutusIsometric exerciseKnee extensionBench pressPlantar flexionH-Reflexoverreaching03 medical and health sciencesYoung Adult0302 clinical medicinePhysical medicine and rehabilitationhermolihasjärjestelmäIsometric ContractionMedicineHumansElbow flexionMuscle Skeletalta315military trainingTraining periodbusiness.industryElectromyographyResistance Training030229 sport sciencesmusculoskeletal systemOverreachingTwitch contractionMilitary PersonnelTreatment OutcomeNeurology (clinical)neuromuscularbusiness030217 neurology & neurosurgeryJournal of Electromyography and Kinesiology
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Fast measurement of auditory event-related potential profiles in 2–3-year-olds

2012

Auditory discrimination, memory, and attention-related functions were investigated in healthy 2-3-year-olds by recording event-related potentials (ERPs) to changes in five auditory features and two types of novel sounds using the fast multifeature paradigm (MFP). ERP profiles consisting of the mismatch negativity (MMN), P3a, and prominent late discriminative negativities (LDN) were obtained, for the first time, from this age group in a considerably shorter time compared to the traditional paradigms. Statistically significant responses from individual children were obtained mainly for the novel sounds. Thus, the MFP shows promise as a time-efficient paradigm for investigating central auditor…

Malemedicine.medical_specialtyTime FactorsBrain activity and meditationAuditory eventMismatch negativityContingent Negative VariationAudiologyElectroencephalography050105 experimental psychologyPitch Discrimination03 medical and health sciencesP3a0302 clinical medicineEvent-related potentialReaction TimeDevelopmental and Educational PsychologymedicineHumansAttention0501 psychology and cognitive sciencesPsychoacoustics10. No inequalityta515Communicationmedicine.diagnostic_testbusiness.industrySensory memory05 social sciencesBrainElectroencephalographyEvent-Related Potentials P300Neuropsychology and Physiological PsychologyAcoustic StimulationChild PreschoolAuditory PerceptionFemalePsychologybusiness030217 neurology & neurosurgeryPsychoacousticsDevelopmental Neuropsychology
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Event-related potentials to pitch and rise time change in children with reading disabilities and typically reading children.

2008

Abstract Objective The purpose of the present study was to investigate whether children with reading disabilities (RD) process rise time and pitch changes differently to control children as a function of the interval between two tones. Methods Children participated in passive oddball event-related potential (ERP) measurements using paired stimuli. Mismatch negativity (MMN), P3a and late discriminative negativity (LDN) responses to rise time and pitch changes were examined. Results Control children produced larger responses than children with RD to pitch change in the P3a component but only when the sounds in the pair were close to each other. Compared to children with RD, MMN was smaller an…

Malemedicine.medical_specialtyTime FactorsMismatch negativityContingent Negative VariationAudiologyNeuropsychological TestsDevelopmental psychologyDyslexiaPitch DiscriminationP3aCommunication disorderEvent-related potentialPhysiology (medical)medicineReaction TimeHumansLanguage disorderChildBrain MappingDyslexiaElectroencephalographymedicine.diseaseSensory SystemsInterval (music)NeurologyAcoustic StimulationReadingRise timeMultivariate AnalysisEvoked Potentials AuditoryFemalesense organsNeurology (clinical)Psychologypsychological phenomena and processesClinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
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Efficacy of switching between tumor necrosis factor-alfa inhibitors in psoriasis: results from the Italian Psocare registry

2014

Background: Some studies have shown that switching patients from one tumor necrosis factor (TNF)-alfa inhibitor to another may be beneficial when they have an inadequate response or an adverse event. Objective: We sought to assess the variables predicting the efficacy of the second TNF-alfa inhibitor in patients discontinuing the first TNF-alfa inhibitor. Methods: Data from all 5423 consecutive patients starting TNF-alfa inhibitor therapy for psoriasis between September 2005 and September 2010 who were included in the Italian Psocare registry were analyzed. Results: In 105 patients who switched to a second TNF-alfa inhibitor who had complete follow-up data, 75% improvement in the Psoriasis …

Maleprimary inefficacy75% improvement in the Psoriasis Area Severity Index score; PASI; PASI 75; Psoriasis Area Severity Index; TNF; biologics; efficacy; primary inefficacy; psoriasis; secondary loss of efficacy; switching; tumor necrosis factor; tumor necrosis factor-alfa inhibitors; Adult; Analysis of Variance; Antibodies Monoclonal; Antibodies Monoclonal Humanized; Cohort Studies; Confidence Intervals; Dose-Response Relationship Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Immunoglobulin G; Italy; Male; Middle Aged; Multivariate Analysis; Predictive Value of Tests; Proportional Hazards Models; Psoriasis; Receptors Tumor Necrosis Factor; Registries; Retrospective Studies; Risk Assessment; Severity of Illness Index; Treatment Outcome; Tumor Necrosis Factor-alpha; Young AdultSWITHCESefficacyTNFpsoriasis; psoriasis arthritis; pharmachological treatmentPASI 75Severity of Illness IndexReceptors Tumor Necrosis FactorEtanerceptCohort StudiesMonoclonalReceptorsSettore MED/35 - Malattie Cutanee E VenereeRegistriesHumanizedtumor necrosis factor-alfa inhibitors.switchingHazard ratioAntibodies MonoclonalMiddle AgedTreatment OutcomeItalyPredictive value of tests75% improvement in the Psoriasis Area Severity Index scoreFemaleDrugPsoriasis Area Severity IndexbiologicTNF-alphaAdultmedicine.medical_specialtytumor necrosis factorDermatology75% improvement in the Psoriasis Area Severity Index score; PASI; PASI 75; Psoriasis Area Severity Index; TNF; biologics; efficacy; primary inefficacy; psoriasis; secondary loss of efficacy; switching; tumor necrosis factor; tumor necrosis factor-alfa inhibitorsAntibodies Monoclonal Humanizedsecondary loss of efficacyRisk AssessmentAntibodiestumor necrosis factor-alfa inhibitorsDrug Administration ScheduleDose-Response RelationshipYoung AdultSettore MED/35Predictive Value of TestsInternal medicinePsoriasisSeverity of illnessmedicineConfidence IntervalsHumansPsoriasisbiologicsAdverse effectPsoriasis; TNF-alphaProportional Hazards ModelsRetrospective Studiespsoriasibiologics; efficacy; primary inefficacy; psoriasis; secondary loss of efficacy; switching; tumor necrosis factor-alfa inhibitors; Adalimumab; Adult; Analysis of Variance; Antibodies Monoclonal; Antibodies Monoclonal Humanized; Cohort Studies; Confidence Intervals; Dose-Response Relationship Drug; Drug Administration Schedule; Etanercept; Female; Follow-Up Studies; Humans; Immunoglobulin G; Infliximab; Italy; Male; Middle Aged; Multivariate Analysis; Predictive Value of Tests; Proportional Hazards Models; Psoriasis; Receptors Tumor Necrosis Factor; Registries; Retrospective Studies; Risk Assessment; Severity of Illness Index; Treatment Outcome; Tumor Necrosis Factor-alpha; Young Adult; 2708Analysis of Variancepharmachological treatmentDose-Response Relationship DrugProportional hazards modelbusiness.industrytumor necrosis factor-alfa inhibitorTumor Necrosis Factor-alphaPASIAdalimumabRetrospective cohort studypsoriasis arthritismedicine.diseaseConfidence intervalInfliximabSurgeryImmunoglobulin GMultivariate AnalysisANTI-TNFAbusiness2708Follow-Up Studies
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Opioid switching in patients with advanced cancer followed at home. A retrospective analysis.

2013

Abstract CONTEXT: Opioid switching has been found to improve opioid responsiveness in different conditions. However, data on opioid switching performed at home are almost nonexistent, despite the fact that most patients are followed at home. OBJECTIVES: The aim of this retrospective survey was to determine frequency, indications, usefulness, and safety of opioid switching when treating advanced cancer-related pain in patients followed at home. METHODS: A retrospective review of data from patients with advanced cancer followed at home by three home care teams for a period of two years was performed. Patients who had their opioids switched were selected. Reasons for switching opioid doses and…

Maleretrospective studyComorbiditySettore MED/42 - Igiene Generale E Applicataadvanced cancer patientNeoplasmsRetrospective analysisPrevalenceOpioid switching; advanced cancer patients; retrospective studyCancer painProspective cohort studyNursing (all)2901 Nursing (miscellaneous)General NursingAnalgesicsDrug SubstitutionHome Care ServicesAnalgesics OpioidCausalitySurvival RateTreatment OutcomeItalyFemaleDrugmedicine.drugmedicine.medical_specialtyAnalgesicPainContext (language use)OpioidDose-Response RelationshipmedicineHumansIn patientIntensive care medicineAgedRetrospective StudiesDose-Response Relationship Drugbusiness.industryAdvanced cancerSurvival AnalysisCancer pain; home care; opioid switching; Aged; Analgesics Opioid; Causality; Comorbidity; Dose-Response Relationship Drug; Drug Substitution; Female; Home Care Services; Humans; Italy; Male; Neoplasms; Pain; Prevalence; Quality of Life; Retrospective Studies; Survival Analysis; Survival Rate; Treatment Outcome; Anesthesiology and Pain Medicine; Neurology (clinical); Nursing (all)2901 Nursing (miscellaneous)Anesthesiology and Pain MedicineOpioidEmergency medicineMorphineOpioid switchingQuality of LifeNeurology (clinical)home carebusinessJournal of pain and symptom management
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Esthétique et politique chez Malévitch

2018

International audience

Malévitch[SHS.ART] Humanities and Social Sciences/Art and art history[SHS] Humanities and Social Sciences[SHS.ART]Humanities and Social Sciences/Art and art historyComputingMilieux_MISCELLANEOUS[SHS]Humanities and Social Sciencespolitique
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Il sostegno e il miglioramento delle coltivazioni sub-tropicali in Sicilia traggono vantaggio dallo studio e dalla promozione delle loro proprietà nu…

2015

Negli ultimi decenni si è assistito a un continuo progresso scientifico in ambito nutrizionale che ha trovato le sue basi da una parte nella scoperta dei principi nutritivi contenuti negli alimenti e dall'altra nell'elaborazione di precise linee guida a larga diffusione. Un'inadeguata alimentazione, infatti, oltre a incidere sul benessere psicofisico, rappresenta uno dei principali fattori di rischio per l'insorgenza di numerose patologie croniche. Secondo l'Organizzazione Mondiale della Sanità (OMS) il rischio di insorgenza di malattie cardiovascolari, metaboliche e di alcuni tumori si abbassa considerevolmente grazie a una corretta e sana alimentazione.

MangoMango; Potenziale antiossidante. Potenziale antinfiammatorio. Potenziale antitumorale. Litchi. Nutraceutica.Settore BIO/10 - BiochimicaPotenziale antiossidante. Potenziale antinfiammatorio. Potenziale antitumorale. Litchi. Nutraceutica.
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Semi-strong efficiency of Bitcoin

2018

Abstract This research examines the semi-strong efficiency of Bitcoin in the Bitstamp and Mt.Gox markets, showing how the digital currency responds to monetary policy and Bitcoin events. On the one hand, we observe that Bitcoin has become more efficient over time in relation to its own events. On the other hand, Bitcoin is not affected by monetary policy news, highlighting the absence of any kind of control on Bitcoin. These findings are relevant for investors and policymakers since Bitcoin is a financial asset without any connection to the measures of central banks.

Market efficiency050208 financeRelation (database)Financial assetCentral banks05 social sciencesMonetary policyControl (management)Market efficiencyMonetary economicsSemi-strong efficiencyDigital currency0502 economics and businessEconomics050207 economicsBitcoinFinanceFinance Research Letters
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Gas-liquid mass transfer rates in unbaffled tanks stirred by PBT: scale-up effects and pumping direction

2018

Abstract Unbaffled stirred tanks are increasingly recognized as a viable alternative to common baffled tanks for a range of applications such as biochemical, food or pharmaceutical processes where the presence of baffles is undesirable for some reason. In this work, the mass transfer performance of unbaffled stirred tanks with pitched blade turbine, operating either in up-pumping or down-pumping mode, was investigated. The influence of impeller size and liquid viscosity were also investigated. The mass transfer intensity was measured by means of the Simplified Dynamic Pressure. Method The measurements concerned both coalescent and non-coalescent (viscous) batches. Results confirm that incre…

Mass transfer coefficientMaterials scienceViscosityGeneral Chemical EngineeringScale-upChemistry (all)Pitched blade turbineBaffleUnbaffled02 engineering and technologyGeneral ChemistryMechanicsDissipation021001 nanoscience & nanotechnologyImpellerViscosity020401 chemical engineeringMass transferSCALE-UPMass transferChemical Engineering (all)0204 chemical engineering0210 nano-technologyIntensity (heat transfer)Fermenter
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