Search results for "Icon"

showing 10 items of 3539 documents

Potato (Solanum tuberosum) Juice Exerts an Anticonvulsant Effect in Mice through Binding to GABA Receptors

2008

Naturally occurring benzodiazepines have been identified in regular food such as wheat and potato, but there is still no evidence that potato extracts can affect CNS responses in vivo. Here we found that undiluted potato juice and potato juice diluted with saline 1 : 2 administered 10 min intracisternally ( I. C.) and 30 min per os before bicuculline exerted significant anticonvulsant activity in the bicuculline-induced seizure threshold test in mice. In vitro, potato juice from different harvests at dilution series from 10 % to 0.000001 %, diluted 100,000-fold, displaced 50 % of gamma-aminobutyric acid (GABA) receptor ligand [ (3)H]GABA and diluted 40-fold displaced 50 % of [(3)H]flunitraz…

Malemedicine.medical_treatmentPharmaceutical SciencePharmacologyPharmacognosyBicucullineMass SpectrometryAnalytical ChemistryMiceReceptors GABAIn vivoDrug DiscoverymedicineAnimalsChromatography High Pressure LiquidSolanum tuberosumPharmacologyMice Inbred ICRDiazepamBehavior AnimalSeizure thresholdPlant ExtractsGABAA receptorChemistryAlkaloidfungiOrganic Chemistryfood and beveragesBicucullineAnticonvulsantComplementary and alternative medicineBiochemistryMolecular MedicineAnticonvulsantsFlunitrazepammedicine.drugPlanta Medica
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Cholecystokinin-8 sulfate modulates the anticonvulsant efficacy of vigabatrin in an experimental model of partial complex epilepsy in the rat.

2009

Summary Purpose:  We evaluated the possible additive effect induced by the administration of the anticonvulsant vigabatrin (VGB) and cholecystokinin-8 sulfate (CCK-8S) on an experimental model of partial complex seizures (maximal dentate gyrus activation, MDA). Moreover, the functional involvement of γ-aminobutyric acid (GABA) neurotransmission was tested by iontophoretically administering bicuculline (GABA receptor antagonist) in the dentate gyrus. Methods:  Urethane anesthetized rats were pretreated with VGB (50, 100 or 200 mg/kg, i.p.) or CCK-8S (8 nmol/kg, i.p.) alone or coadministered with VGB (50 mg/kg, i.p.). Dentate gyrus epileptic activity was obtained through the repetitive electr…

Malemedicine.medical_treatmentStimulationConvulsantsNeurotransmissionPharmacologyBicucullineRat Partial epilepsy Vigabatrin Cholecystokinin-8 sulfate ControlVigabatrinDrug Administration ScheduleSincalideVigabatrinEpilepsy Complex PartialmedicineReaction TimeAnimalsRats WistarEvoked PotentialsNootropic AgentsAnalysis of VarianceIontophoresisDose-Response Relationship DrugChemistryDentate gyrusDrug SynergismBicucullineGABA receptor antagonistElectric StimulationRatsDisease Models AnimalAnticonvulsantNeurologyAnesthesiaDentate GyrusAnticonvulsantsDrug Therapy CombinationNeurology (clinical)medicine.drugEpilepsia
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Dal riconoscimento "automatico" al riconoscimento "implicito": una tesi poco convincente

2014

L’Autrice, dopo avere dato conto dell’evoluzione normativa in tema di mandato di arresto europeo e mutuo riconoscimento, contesta la tesi adottata dalla Suprema Corte, secondo cui la richiesta ex art. 18, lett. r), L. n. 69/2005 si fonderebbe sul riconoscimento “implicito” della sentenza straniera da parte dell’interessato, che, pertanto, perderebbe l’interesse a dedurre eventuali violazioni del diritto a un processo equo, ritenendola ormai superata alla luce delle nuove regole introdotte dal D.lgs. n. 161/2010 e dall’art. 4 bis della decisione quadro 2002/584/GAI, così come emendata nel 2009, in virtù delle quali l’autorità richiesta è tenuta al “formale” riconoscimento del provvedimento d…

Mandato di arresto europeo - Riconoscimento - Decisione quadro - Processo equo - Esecuzione
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Mappings of finite distortion from generalized manifolds

2014

We give a definition for mappings of finite distortion from a generalized manifold with controlled geometry to a Euclidean space. We prove that the basic properties of mappings of finite distortion are valid in this context. In particular, we show that under the same assumptions as in the Euclidean case, mappings of finite distortion are open and discrete.

Mappings of finite distortionDistortionQuasiconformal mappingsGeometry and TopologyTopologyMathematics
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Simulation of the influence of gas flow on melt convection and phase boundaries in FZ silicon single crystal growth

2015

Abstract Axisymmetric calculations of inert gas flow in a floating zone puller are carried out using an open source software package OpenFOAM. Transient axisymmetric melt flow in liquid silicon and quasi-stationary shape of silicon phase boundaries are calculated using a specialized program FZone. Additional heat losses at silicon surfaces caused by the gas flow are taken into account for argon and helium, while maintaining the height of molten zone by adjusting inductor current. Cooling causes an increase of electromagnetic force, heat sources and more intense melt flow, while crystallization interface deflection decreases. The shear stress of gas flow is found to be an order of magnitude …

Marangoni effectArgonMaterials scienceSiliconchemistry.chemical_elementMechanicsCondensed Matter Physicslaw.inventionPhysics::Fluid DynamicsInorganic ChemistrychemistrylawMaterials ChemistryShear stressCrystallizationInert gasHeliumMelt flow indexJournal of Crystal Growth
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Stackelberg equilibrium with multiple firms and setup costs

2017

Abstract I provide conditions that guarantee that a Stackelberg game with a setup cost and an integer number of identical leaders and followers has an equilibrium in pure strategies. The main feature of the game is that when the marginal follower leaves the market the price jumps up, so that a leader’s payoff is neither continuous nor quasiconcave. To show existence I check that a leader’s value function satisfies the following single crossing condition: When the other leaders produce more the leader never accommodates entry of more followers. If demand is strictly logconcave, and if marginal costs are both non decreasing and not flatter than average costs, then a Stackelberg equilibrium ex…

Marginal costStackelberg equilibriumEconomics and EconometricsSetup costApplied Mathematics05 social sciencesStochastic gameExistence of the equilibriumSupermodular gamesCournot competitionSettore SECS-P/06 - Economia ApplicataMicroeconomicsQuasiconvex functionNon quasiconcave payoffEntry deterrenceBellman equation0502 economics and businessEconomicsStackelberg competitionMarket powerLimit (mathematics)050207 economicsSettore SECS-P/01 - Economia PoliticaMathematical economics050205 econometrics Journal of Mathematical Economics
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Mario di Laurito, Madonna dell’Itria, 1529-1536

2022

Observations on the canvas, due to the brush of Mario de Laurito, an elegant painter of composite culture active between Naples and Sicily in the first half of XVI century, it came to the Diocesan Museum of Palermo from the local church of the archconfraternity of the Santissima Annunziata "outside Porta San Giorgio "(late fifteenth - early sixteenth century, for which Travagliato 2010) fortunately shortly before the allied bombings on Palermo which between April and May 1943 caused the destruction (Guiotto 1946).

Marian iconographySettore L-ART/01 - Storia Dell'Arte MedievaleMario di LauritoDiocesan MuseumMadonna of the ItriaRenaissance paintingSicilyPalermo
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Pittore attivo in Sicilia nella seconda metà del XV secolo, Madonna dell’Itria

2022

The complex conservative history of the work, the Madonna dell’Itria, executed in fresco, detached from the back wall of the presbytery of the eponymous sacred building and restored in 1990, then transferred to the Diocesan Museum of Palermo

Marian iconographylate Gothic paintingSettore L-ART/01 - Storia Dell'Arte MedievaleDiocesan MuseumMadonna of the ItriaSicilyPalermo
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FROM Δηομένη TO Madonna dell’Itria... AND VICEVERSA. TWO MARIAN ICONOGRAPHIES SUPERIMPOSED IN A “PALIMPSEST WALL” OF MARSALA (TP)

2019

During a recent restoration in an underground chapel in Marsala (TP), the wall to which the altar is attached proved to be a palimpsest of several layers. The oldest dated back from the late twelfth to early thirteenth century displaying a “velarium” in the lower register. Overhead we see a Madonna in prayer (Δηομένη) preceded by a theory of Saints. A second layer, from the 15th century, decisively changes the original iconography thus transforming it into the typically Sicilian iconography of the “Madonna dell’Itria”. The Child, positioned in the center of the Mother’s breast, sits inside a chest supported by two old chants. The latter devotional image, due to the perishability of the plas…

Marian iconographyrestorationsacred artSettore L-ART/01 - Storia Dell'Arte Medievalemedieval Sicilyrock art
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A Decision Model for the Multiple Criteria Group Secretary Problem: Theoretical Considerations

1996

A decision model is developed for solving the discrete multiple criteria group secretary problem. The model extends the single decision-maker progressive algorithm by Korhonen, Moskowitz and Wallenius to group contexts. As the original progressive algorithm, it relaxes the usual assumption of a fixed set of available decision alternatives and complete knowledge of a decision-maker's preference structure (value function). The decision-makers are requested to settle on a compromise, if possible. The model then proceeds with determining the likelihood of finding possibly/surely better settlements (compromises). Linear value functions, linear prospect theory-type value functions, and quasiconca…

MarketingOperations researchComputer scienceStrategy and ManagementStructure (category theory)Management Science and Operations ResearchConflict analysisManagement Information SystemsQuasiconvex functionBellman equationConflict resolutionMultiple criteriaProduction (economics)Mathematical economicsValue (mathematics)Preference (economics)Decision modelSecretary problemJournal of the Operational Research Society
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