Search results for "IgG"
showing 10 items of 1389 documents
Oxygen Transmissibility of Piggyback Systems With Conventional Soft and Silicone Hydrogel Contact Lenses
2006
To investigate the apparent oxygen transmissibility of various piggyback systems using conventional and silicone hydrogel soft contact lenses of different water content and permeability, rigid poly(methyl methacrylate), and rigid gas-permeable lenses of medium, high, and ultrahigh oxygen permeability. The aim of the study was to establish which material (rigid or hydrogel) is more representative of the resulting oxygen performance of piggyback systems. METHODS: The apparent oxygen transmissibility of 66 piggyback systems was measured with an electrochemical method. Eighteen of these combinations involved the use of silicone hydrogel contact lenses currently available. One hyperpermeable rig…
Label-free wavelength and phase detection based SMS fiber immunosensors optimized with cladding etching
2018
The performance of E-SMS (Etched Singlemode-Multimode-Singlemode) optical fiber structures as immunosensors has been assessed by the implementation of antibody/antigen immunoassays. Through this procedure it has been proven that E-SMS structures are effective and suitable optical platforms for label-free biosensing. Using the phase shift and tracking the wavelength response it was found that the fabricated E-SMS devices exhibited limits of detection (LOD) down up to concentrations of 0.2mg/L of antigens in solution. This was achieved by coating the E-SMS with an antibody-based biolayer (goat IgG) that is able to determine the presence of anti-goat IgG antigen. Both a wavelength detection an…
Epšteina-Barra vīrusa ietekme uz multiplās sklerozes pacientu klīnisku gaitu un magnētiskā rezonansa izmaiņām atkarībā no Anti-Epšteina-Barra vīrusa …
2016
Multiplā skleroze jeb izkaisītā skleroze ir autoimūnas dabas neiroloģiskā saslimšana. Ar MS slimo visā pasaulē. Tomēr, pēc epidemioloģiskiem datiem MS vairāk sastop Ziemeļvalstīs, ka arī Latvijā tā ir diezgan izplatīta. Līdz šīm slimības etioloģiskais faktors nav zināms. Ir vairākas hipotēzes, dažas no tiem ir zinātniski apstiprinātas, bet dažas atrodas izpētes līmenī. Mūsu pētījuma mērķis ir pierādīt EBV vīrusa infekcijas iesaistību šajā slimībā. Noskaidrot EBV infekcijas lomu slimības progresijā. Lai realizēt mūsu mērķus, mēs izveidojām pētijuma un kontrolgrupu, rezultātā pacientu kopējas skaits bija 60 cilvēki. Vidējais vecums pētijuma grupā bija 40 ± 12.938 gadi un kontrolgrupā 37.47 ± …
Hardware and firmware developments for the upgrade of the ATLAS Level-1 Central Trigger Processor
2014
The Central Trigger Processor (CTP) is the final stage of the ATLAS first level trigger system which reduces the collision rate of 40 MHz to a Level-1 event rate of 100 kHz. An upgrade of the CTP is currently underway to significantly increase the number of trigger inputs and trigger combinations, allowing additional flexibility for the trigger menu. We present the hardware and FPGA firmware of the newly designed core module (CTPCORE+) module of the CTP, as well as results from a system used for early firmware and software prototyping based on commercial FPGA evaluation boards. First test result from the CTPCORE+ module will also be shown.
Higgs boson studies at the Tevatron
2013
We combine searches by the CDF and D0 Collaborations for the standard model Higgs boson with mass in the range 90-200 GeV/c2 produced in the gluon-gluon fusion, WH, ZH, tt̄H, and vector boson fusion processes, and decaying in the H→bb̄, H→W+W-, H→ZZ, H→τ+τ-, and H→γγ modes. The data correspond to integrated luminosities of up to 10 fb-1 and were collected at the Fermilab Tevatron in pp̄ collisions at √s=1.96 TeV. The searches are also interpreted in the context of fermiophobic and fourth generation models. We observe a significant excess of events in the mass range between 115 and 140 GeV/c2. The local significance corresponds to 3.0 standard deviations at mH=125 GeV/c2, consistent with the…
Evidence for a Particle Produced in Association with Weak Bosons and Decaying to a Bottom-Antibottom Quark Pair in Higgs Boson Searches at the Tevatr…
2012
Aaltonen, T. et al.
Measurement of the cosmic ray energy spectrum using hybrid events of the Pierre Auger Observatory
2012
The energy spectrum of ultra-high energy cosmic rays above 10$^{18}$ eV is measured using the hybrid events collected by the Pierre Auger Observatory between November 2005 and September 2010. The large exposure of the Observatory allows the measurement of the main features of the energy spectrum with high statistics. Full Monte Carlo simulations of the extensive air showers (based on the CORSIKA code) and of the hybrid detector response are adopted here as an independent cross check of the standard analysis (Phys. Lett. B 685, 239 (2010)). The dependence on mass composition and other systematic uncertainties are discussed in detail and, in the full Monte Carlo approach, a region of confiden…
Meshless Electrophysiological Modeling of Cardiac Resynchronization Therapy—Benchmark Analysis with Finite-Element Methods in Experimental Data
2022
Computational models of cardiac electrophysiology are promising tools for reducing the rates of non-response patients suitable for cardiac resynchronization therapy (CRT) by optimizing electrode placement. The majority of computational models in the literature are mesh-based, primarily using the finite element method (FEM). The generation of patient-specific cardiac meshes has traditionally been a tedious task requiring manual intervention and hindering the modeling of a large number of cases. Meshless models can be a valid alternative due to their mesh quality independence. The organization of challenges such as the CRT-EPiggy19, providing unique experimental data as open access, enables b…
Spacetime curvature and Higgs stability after inflation
2015
We investigate the dynamics of the Higgs field at the end of inflation in the minimal scenario consisting of an inflaton field coupled to the Standard Model only through the non-minimal gravitational coupling $\xi$ of the Higgs field. Such a coupling is required by renormalisation of the Standard Model in curved space, and in the current scenario also by vacuum stability during high-scale inflation. We find that for $\xi\gtrsim 1$, rapidly changing spacetime curvature at the end of inflation leads to significant production of Higgs particles, potentially triggering a transition to a negative-energy Planck scale vacuum state and causing an immediate collapse of the Universe.
Postinationary vacuum instability and Higgs-inflaton couplings
2016
The Higgs-inflaton coupling plays an important role in the Higgs field dynamics in the early Universe. Even a tiny coupling generated at loop level can have a dramatic effect on the fate of the electroweak vacuum. Such Higgs-inflaton interaction is present both at the trilinear and quartic levels in realistic reheating models. In this work, we examine the Higgs dynamics during the preheating epoch, focusing on the effects of the parametric and tachyonic resonances. We use lattice simulations and other numerical tools in our studies. We find that the resonances can induce large fluctuations of the Higgs field which destabilize the electroweak vacuum. Our considerations thus provide an upper …