Search results for "IgG"
showing 10 items of 1389 documents
Gated mesoporous silica nanoparticles for the controlled delivery of drugs in cancer cells
2015
In recent years, mesoporous silica nanoparticles (MSNs) have been used as effective supports for the development of controlled-release nanodevices that are able to act as multifunctional delivery platforms for the encapsulation of therapeutic agents, enhancing their bioavailability and overcoming common issues such as poor water solubility and poor stability of some drugs. In particular, redox-responsive delivery systems have attracted the attention of scientists because of the intracellular reductive environment related to a high concentration of glutathione (GSH). In this context, we describe herein the development of a GSH-responsive delivery system based on poly(ethylene glycol)- (PEG-)…
Glucose-triggered release using enzyme-gated mesoporous silica nanoparticles.
2013
[EN] A new gated nanodevice design able to control cargo delivery using glucose as a trigger and cyclodextrin-modified glucose oxidase as a capping agent is reported.
Poly(N-isopropylacrylamide)-gated Fe3O4/SiO2 core shell nanoparticles with expanded mesoporous structures for the temperature triggered release of ly…
2015
Core-shell nanoparticles comprised of Fe3O4 cores and a mesoporous silica shell with an average expanded pore size of 6.07 nm and coated with a poly(N-isopropylacrylamide) (PNIPAM) layer (CS MSNs EP PNIPAM) were prepared and characterized. The nanoparticles was loaded with (Ru(bipy)3 2+) dye or an antibacterial enzyme, lysozyme, to obtain CS MSNs EP PNIPAM Ru(bipy)3 2+ and CS MSNs EP PNIPAM Lys, respectively. The lysozyme loading was determined to be 160 mg/g of nanoparticle. It was seen that Ru(bipy)3 2+ and lysozyme release was minimal at a room temperature of 25 ºC while at physiological temperature (37 º C), abrupt release was observed. The applicability of the CS MSNs EP PNIPAM Lys was…
Centri storici manomessi: “antichi” come nuovi!
2012
The chapter presents the results of urban planning in Italy since 1950 and introduces the theories developed by Muratori and Caniggia for the restoration of historical centers. The paper critically shows some examples of typological restoration and introduces the debate that has developed around the outcomes of interventions.
Boosting the in situ encapsulation of proteins with MIL-100(Fe): the role of strong Lewis acid centers
2021
Encapsulation of biomolecules using Metal-Organic Frameworks (MOFs) to form stable biocomposites has been demonstrated a valuable strategy for their preservation and controlled release, which has been however restricted to specific electrostatic surface conditions. We present a general in situ strategy that promotes the spontaneous MOF growth onto a broad variety of proteins, for the first time, regardless of their surface nature. We demonstrate that MOFs based on cations exhibiting considerable inherent acidity such as MIL-100(Fe) enable biomolecule encapsulation, including alkaline proteins previously inaccesible by the welldeveloped in situ encapsulation with azolate-based MOFs. In parti…
"Table 43" of "Search for heavy Higgs bosons decaying into two tau leptons with the ATLAS detector using $pp$ collisions at $\sqrt{s}=13$ TeV"
2020
Expected two dimensional likelihood scan of the gluon-gluon fusion cross section times branching fraction, $\sigma(gg\phi)\times B(\phi\to\tau\tau)$, vs the b-associated production times branching fraction, $\sigma(bb\phi)\times B(\phi\to\tau\tau)$ for the scalar boson mass ($m_\phi$) indicated in the table. For each mass, 10000 points are scanned. At each point $\Delta(\mathrm{NLL})$ is calculated, defined as the negative-log-likelihood (NLL) of the conditional fit with $\sigma(gg\phi)$ and $\sigma(bb\phi)$ fixed to their values at the point and with the minimum NLL value at any point subtracted. The best-fit point and the preferred 68% and 95% boundaries are found at $2\Delta(\mathrm{NLL}…
"Table 2" of "Measurement of Higgs boson production in the diphoton decay channel in $pp$ collisions at center-of-mass energies of 7 and 8 TeV with t…
2015
The signal strength for a Higgs boson of mass mH = 125.4 GeV decaying via H->gammagamma as measured in groups of categories sensitive to individual production modes, and the combined signal strength, for the combination of the 7 TeV and 8 TeV data.
"Table 1" of "Measurement of Higgs boson production in the diphoton decay channel in $pp$ collisions at center-of-mass energies of 7 and 8 TeV with t…
2015
The signal strength for a Higgs boson of mass mH = 125.4 GeV decaying via H->gammagamma as measured in the individual analysis categories, and the combined signal strength, for the combination of the 7 TeV and 8 TeV data. The VH dilepton category is not shown because with only two events in the combined sample, the fit results are not meaningful.
"Table 3" of "Measurement of Higgs boson production in the diphoton decay channel in $pp$ collisions at center-of-mass energies of 7 and 8 TeV with t…
2015
Measured signal strengths, for a Higgs boson of mass mH = 125.4 GeV decaying via H->gammagamma, of the different Higgs boson production modes and the combined signal strength mu obtained with the combination of the 7 TeV and 8 TeV data.
"Table 15" of "Measurements of the Total and Differential Higgs Boson Production Cross Sections Combining the $H \rightarrow \gamma \gamma$ and $H \r…
2016
Correlation matrix for the total uncertainty of the differential shape measurement in bins of $N_{\rm{jets}}$.