Search results for "Importance"
showing 10 items of 81 documents
Importance sampling type estimators based on approximate marginal Markov chain Monte Carlo
2020
We consider importance sampling (IS) type weighted estimators based on Markov chain Monte Carlo (MCMC) targeting an approximate marginal of the target distribution. In the context of Bayesian latent variable models, the MCMC typically operates on the hyperparameters, and the subsequent weighting may be based on IS or sequential Monte Carlo (SMC), but allows for multilevel techniques as well. The IS approach provides a natural alternative to delayed acceptance (DA) pseudo-marginal/particle MCMC, and has many advantages over DA, including a straightforward parallelisation and additional flexibility in MCMC implementation. We detail minimal conditions which ensure strong consistency of the sug…
Response to Skeide and Friederici: The myth of the uniquely human “direct” dorsal pathway
2015
In their comment on our recent article [1], Skeide and Friederici [2] claim ‘that some important data not discussed by Bornkessel-Schlesewsky et al. strongly support the view that there are clear qualitative, and not merely quantitative, differences between [human and nonhuman primate] species with respect to both the intrinsic functional connectivity of frontal and temporal cortices, and their direct structural connection via a dorsal white matter fiber tract.’ This obviously refers to work by Friederici and colleagues [3] emphasizing the functional importance of a direct connection between the posterior superior temporal cortex (pSTC) and Brodmann area (BA) 44 in humans, and its absence i…
Event generation and statistical sampling for physics with deep generative models and a density information buffer
2021
Simulating nature and in particular processes in particle physics require expensive computations and sometimes would take much longer than scientists can afford. Here, we explore ways to a solution for this problem by investigating recent advances in generative modeling and present a study for the generation of events from a physical process with deep generative models. The simulation of physical processes requires not only the production of physical events, but to also ensure that these events occur with the correct frequencies. We investigate the feasibility of learning the event generation and the frequency of occurrence with several generative machine learning models to produce events l…
DECORIN EFFECTS ON PROTEOMIC PROFILING OF BREAST CANCER CELLS: AN UPDATED STUDY
2015
The malignant carcinomas are characterized by several capabilities acquired by the neoplastic cells, among which the ability to invade the extracellular matrix (ECM) and to establish a crosstalk with several ECM components. Under this respect, the extracellular microenvironment is an entity extraordinarily rich of information with opposite signals. Our group has long undertaken the study of the effects of ECM molecules on the behavior of cancer cells in vitro. Among the studied molecules, the decorin was found to exert a non-permissive effect on the growth and motility of the transfected tumor cells. The decorin, belongs to the family of small leucine-rich proteoglycans (SLRP) and is involv…
L’èxtasi poètic de Fontanella: metateatre i música a la Lloa per la Tragicomèdia pastoral d’amor, firmesa i porfia
2018
Resum: En absència d’estudis monogràfics sobre la Lloa de Fontanella, aquest article n’ analitza l’estructura dramàtica, començant amb una reflexió sobre llur classificació dintre del gènere i sobre l’espai de la Barcelona del segle XVII que podria haver-la escenificat. La importància funcional que el poeta barceloní atorga a la música i al metateatre condueixen a una interpretació de la Lloa des d’un punt de vista poeticomusical, la qual cosa permet una nova lectura de certs passatges i una valoració crítica que afecta, no només a la peça en qüestió sinó a tota la Tragicomèdia pastoral d’amor, firmesa i porfia i al caràcter d’avantguarda del teatre català de l’Edat Moderna
 Paraules c…
Aportaciones documentales sobre cruces de orfebrería valencianas. Siglos XIV y XV
2020
The article intends to make a contribution of new documentary references, from the notarial funds of the Valencian archives, in which news about parish crosses and Lignum Crucis from the silversmith center of Valencia during the fourteenth and fifteenth centuries are collected. The importance of these typologies lies in being the main elements of Christian worship, so it was an essential piece in each parish that allowed the provision in them of models of varied typology and functionality; for that reason they are conserved from altar crosses, cross-shaped reliquaries ?known as Lignum Crucis or Veracruz ?to processional crosses, larger and representative of the parish community to which it …
Du verbe instrumental dans la musique subsaharienne
2021
Sub-Saharan music results from the spoken language/instrumental language relation, directed by an oral culture. In this culture, these languages transmit ? beyond their singularities ? messages thanks to either a coded signal known by the linguistic community or previously defined among a group of individuals, or is used as a true meta-language copied on the articulated and usual language used every day. Here, an instrumental musical speech can then imitate and reproduce the tonal inflexions of the language to make its matter understandable. This fact is the natural result of a strong interaction and interrelation between the spoken language and the music as well as the conception that the …
Estudios previos y propuesta de intervención en las pinturas murales, esculturas y ornamentos de la Real Parroquia de los Santos Juanes de Valencia
2020
Throughout this article, the most representative aspects of the previous studies and the intervention proposal, carried out for the restoration of the paintings, sculptures and ornaments of the Royal Parish of the Santos Juanes in Valencia, are exposed. A project of this magnitude involves the effort and dedication of a great team, resulting in one-year work with exhaustive and constant research with the purpose of safeguarding the heritage assets of the church. With this article we want to make known the importance that these previous studies acquire. Been essential since they are the starting point and the basis for the execution of the restoration works that will be carried out during fo…
Eclecticismo, Écart y alteridad: Symphony V American, de Leonardo Balada, como paradigma compositivo
2021
Eclecticism is a complex creative trend born as a consequence of both postmodernism and the heterodox treatment of cultural identity borders. This aesthetic path emerges as a compositional model of great communicative power in contemporary creation in the last two decades. Our essay addresses the Symphony V "American" (2003) by Leonardo Balada (1933) as a compositional paradigm. Through this article we demonstrate the importance of including popular sounds and re-signifying materials in the creative conception. A valid model of communication ahead of the challenges of globalization and mass media processes is therefore established hereby.
The role of the thalamus in the human subcortical vestibular system1
2014
Most of our knowledge concerning central vestibular pathways is derived from animal studies while evidence of the functional importance and localization of these pathways in humans is less well defined. The termination of these pathways at the thalamic level in humans is even less known. In this review we summarize the findings concerning the central subcortical vestibular pathways in humans and the role of these structures in the central vestibular system with regard to anatomical localization and function. Also, we review the role of the thalamus in the pathogenesis of higher order sensory deficits such as spatial neglect, pusher syndrome or thalamic astasia and the correlation of these p…