Search results for "Inference"

Affine Invariant Multivariate Sign and Rank Tests and Corresponding Estimates: a Review

1999

The paper reviews recent contributions to the statistical inference methods, tests and estimates, based on the generalized median of Oja. Multivariate analogues of sign and rank concepts, affine invariant one-sample and two-sample sign tests and rank tests, affine equivariant median and Hodges–Lehmann-type estimates are reviewed and discussed. Some comparisons are made to other generalizations. The theory is illustrated by two examples.

Unacceptable implications of the left haar measure in a standard normal theory inference problem

1978

For a very common statistical problem, inference about the mean of a normal random variable, some inadmissible consequences of the left Haar invariant prior measure, which is that recommended as a suitable prior by Jeffreys’ multivariate rule and by the methods of Villegas and Kashyap, are uncovered and investigated.

A Software Tool For Sparse Estimation Of A General Class Of High-dimensional GLMs

2022

Generalized linear models are the workhorse of many inferential problems. Also in the modern era with high-dimensional settings, such models have been proven to be effective exploratory tools. Most attention has been paid to Gaussian, binomial and Poisson settings, which have efficient computational implementations and where either the dispersion parameter is largely irrelevant or absent. However, general GLMs have dispersion parameters φ that affect the value of the log- likelihood. This in turn, affects the value of various information criteria such as AIC and BIC, and has a considerable impact on the computation and selection of the optimal model.The R-package dglars is one of the standa…

A critical evaluation of the current “p-value controversy”

2017

This article has been triggered by the initiative launched in March 2016 by the Board of Directors of the American Statistical Association (ASA) to counteract the current p-value focus of statistical research practices that allegedly "have contributed to a reproducibility crisis in science." It is pointed out that in the very wide field of statistics applied to medicine, many of the problems raised in the ASA statement are not as severe as in the areas the authors may have primarily in mind, although several of them are well-known experts in biostatistics and epidemiology. This is mainly due to the fact that a large proportion of medical research falls under the realm of a well developed bo…

Frequentist and Bayesian approaches for a joint model for prostate cancer risk and longitudinal prostate-specific antigen data

2015

The paper describes the use of frequentist and Bayesian shared-parameter joint models of longitudinal measurements of prostate-specific antigen (PSA) and the risk of prostate cancer (PCa). The motivating dataset corresponds to the screening arm of the Spanish branch of the European Randomized Screening for Prostate Cancer study. The results show that PSA is highly associated with the risk of being diagnosed with PCa and that there is an age-varying effect of PSA on PCa risk. Both the frequentist and Bayesian paradigms produced very close parameter estimates and subsequent 95% confidence and credibility intervals. Dynamic estimations of disease-free probabilities obtained using Bayesian infe…

Statistical inference as a decision problem: the choice of sample size

1997

Analysis of the renal transplant waiting list in the País Valencià (Spain).

2005

In this paper we analyse the renal transplant waiting list of the Pais Valencia in Spain, using Queueing theory. The customers of this queue are patients with end-stage renal failure waiting for a kidney transplant. We set up a simplified model to represent the flow of the customers through the system, and perform Bayesian inference to estimate parameters in the model. Finally, we consider several scenarios by tuning the estimations achieved and computationally simulate the behaviour of the queue under each one. The results indicate that the system could reach equilibrium at some point in the future and the model forecasts a slow decrease in the size of the waiting list in the short and mid…

The “ThreePlusOne” Likelihood-Based Test Statistics: Unified Geometrical and Graphical Interpretations

2014

The presentation of the well known Likelihood Ratio, Wald and Score test statistics in textbooks appears to lack a unified graphical and geometrical interpretation. We present two simple graphical representations on a common scale for these three test statistics, and also the recently proposed Gradient test statistic. These unified graphical displays may favour better understanding of the geometrical meaning of the likelihood based statistics and provide useful insights into their connections.

Testing with a nuisance parameter present only under the alternative: a score-based approach with application to segmented modelling

2016

ABSTRACTWe introduce a score-type statistic to test for a non-zero regression coefficient when the relevant term involves a nuisance parameter present only under the alternative. Despite the non-regularity and complexity of the problem and unlike the previous approaches, the proposed test statistic does not require the nuisance to be estimated. It is simple to implement by relying on the conventional distributions, such as Normal or t, and it justified in the setting of probabilistic coherence. We focus on testing for the existence of a breakpoint in segmented regression, and illustrate the methodology with an analysis on data of DNA copy number aberrations and gene expression profiles from…

Likelihood Inference for Gibbs Processes in the Analysis of Spatial Point Patterns

2001

Plusieurs auteurs ont propose des approximations stochastiques et non-stochastiques au MLE pour les processus de Gibbs utilises pour decrire les interactions entre deux points dans une distribution spatiale de points. Cettes approximations sont necessaires a cause de la difficulte en l'evaluation de la constante qui normalise la f.d.p., Cet article present une comparaison, parmi d'un model de Strauss, des methodes qui utilisent des approximations directes aux MLE et des methodes qui utilisent techniques de Monte Carlo de chaine de Markov. Les techniques de simulation utilisees sont le Gibbs sampler et l'algorithm de Metropolis-Hastings.