Search results for "Injection"

A statistical design of experiments for optimizing the MALDI-TOF-MS sample preparation of polymers. An application in the assessment of the thermo-me…

2011

[EN] The sample preparation procedure for MALDI-TOF MS of polymers is addressed in this study by the application of a statistical Design of Experiments (DoE). Industrial poly (ethylene terephthalate) (PET) was chosen as model polymer. Different experimental settings (levels) for matrixes, analyte/matrix proportions and concentrations of cationization agent were considered. The quality parameters used for the analysis were signal-to-noise ratio and resolution. A closer inspection of the statistical results provided the study not only with the best combination of factors for the MALDI sample preparation, but also with a better understanding of the influence of the different factors, individua…

Assessing the MALDI-TOF MS sample preparation procedure to analyze the influence of thermo-oxidative ageing and thermo-mechanical degradation on poly…

2011

[EN] Multiple processing by means of successive injection cycles was used to simulate the thermo-mechanical degradation effects on the oligomeric distribution of PLA under mechanical recycling. Likewise, an accelerated thermal ageing over PLA glass transition was performed in order to simulate its service life. MALDI-TOF MS was used for the analysis and the sample preparation procedure was assessed by means of a statistical Design of Experiments (DoE). The quality effects in use for the analysis were signal-to-noise ratio and Resolution. Different matrixes, analyte/matrix proportions and the use of NaTFA as cationization agent were considered. A deep inspection of the statistical results pr…

Multimodal approaches to the treatment of hepatocellular carcinoma.

2008

The prevalence of hepatocellular carcinoma in Europe and the US is increasing and is currently the leading cause of death in patients with cirrhosis. Surveillance programs for patients with cirrhosis aim to detect tumors at an early stage, when the greatest therapeutic benefits can be achieved. Curative treatments for early-stage tumors include liver transplantation, resection and percutaneous ablation. Transarterial chemoembolization (TACE) and sorafenib can improve survival for patients with intermediate and advanced tumors, respectively. In clinical practice, combination therapies are often used, despite limited evidence to support this approach from randomized controlled trials. Combina…

Towards minimization of chlorinated solvents consume in Fourier transform infrared spectroscopy determination of Propamocarb in pesticide formulation…

2008

Abstract A method has been developed for Fourier transform infrared (FTIR) spectroscopy determination of Propamocarb in emulsifiable pesticide concentrate formulations. Five microliter sample was directly injected without any pretreatment in a CHCl 3 stream at 2 mL min −1 into a closed system and the FTIR spectra of sample and standard solutions were obtained using a nominal resolution of 4 cm −1 from 4000 to 900 cm −1 spectral region and accumulating 2 scans per spectrum. Propamocarb determination was based on the measurement of flow injection analysis (FIA) recording height established from FTIR peak area measurements from 1713 to 1703 cm −1 corrected using a baseline defined at 2000 cm −…

Cutaneous Exposure to the Superantigen Staphylococcal Enterotoxin B Elicits a T-Cell-Dependent Inflammatory Response

1996

We analyzed the impact of superantigens secreted by skin-colonizing Staphylococci on the skin and the associated lymphoid tissue following epicutaneous application and intracutaneous injection of small amounts of staphylococcal enterotoxin B (SEB). A single intracutaneous injection of 50 ng of SEB elicited a strong inflammatory response in the skin of BALB/c mice. Three to 6 h later, we observed langerhans cell activation, mast cell degranulation, vasodilation, upregulation of ICAM-1, and induction of VCAM-1 on dermal blood vessels, with vascular adhesion of granulocytes. by 12 to 24 h, cell infiltration of the dermis increased, reaching the epidermis. Among the infiltrating leukocytes, a s…

Le specie alloctone invasive in Sicilia: caratterizzazione del fenomeno, strategie di colonizzazione e possibili strategie di contrasto

2014

Analysis of the influence of processor hidden registers on the accuracy of fault injection techniques

2004

Modern processors tend to increase the number of registers, being part of them not accessible by the instruction set. Traditionally, the effect of faults in these hidden registers has not been considered during system validation using fault injection. In this paper, a study of the importance of faults in hidden registers is performed. Firstly, we have analysed the sensitivity of hidden registers to faults in combinational logic. In a second phase, we have analysed the impact of the faults occurred in hidden registers on system behaviour. A broad set of permanent and transient faults have been injected into the models of two typical commercial microcontrollers, using a VHDL-based fault injec…

Platelet rich plasma ( PRP) injection and hydrokinesitherapy for Achilles tendon sprain:our experience .

2011

Pigment epithelium-derived factor is a niche signal for neural stem cell renewal.

2006

Adult stem cells are characterized by self-renewal and multilineage differentiation, and these properties seem to be regulated by signals from adjacent differentiated cell types and by extracellular matrix molecules, which collectively define the stem cell "niche." Self-renewal is essential for the lifelong persistence of stem cells, but its regulation is poorly understood. In the mammalian brain, neurogenesis persists in two germinal areas, the subventricular zone (SVZ) and the hippocampus, where continuous postnatal neuronal production seems to be supported by neural stem cells (NSCs). Here we show that pigment epithelium-derived factor (PEDF) is secreted by components of the murine SVZ a…

Experimental model-based linearization of a S.I. engine gas injector flow chart:

2014

Experimental tests previously executed by the authors on the simultaneous combustion of gasoline and gaseous fuel in a spark ignition engine revealed the presence of strong nonlinearities in the lower part of the gas injector flow chart. These nonlinearities arise via the injector outflow area variation caused by the needle impacts and bounces during the transient phenomena that take place in the opening and closing phases of the injector and may seriously compromise the air-fuel mixture quality control for the lower injection times, thus increasing both fuel consumption and pollutant emissions. Despite the extensive literature about the operation and modelling of fuel injectors, there are …