Search results for "Injection"
showing 10 items of 920 documents
Fault Emulation for Dependability Evaluation of VLSI Systems
2008
Advances in semiconductor technologies are greatly increasing the likelihood of fault occurrence in deep-submicrometer manufactured VLSI systems. The dependability assessment of VLSI critical systems is a hot topic that requires further research. Field-programmable gate arrays (FPGAs) have been recently pro posed as a means for speeding-up the fault injection process in VLSI systems models (fault emulation) and for reducing the cost of fixing any error due to their applicability in the first steps of the development cycle. However, only a reduced set of fault models, mainly stuck-at and bit-flip, have been considered in fault emulation approaches. This paper describes the procedures to inje…
The effect of metals on condition and pathologies of European eel (Anguilla anguilla): in situ and laboratory experiments.
2011
Forty-nine wild eels (Anguilla anguilla) caught in the Albufera Lake (Spain), measuring 24.0-75.0 cm in length and 25.0-637.7 g in weight, were examined for metals (Cd, Co, Cr, Cu, Fe, Hg, Mn, Pb, Se and Zn), condition (CI and HSI indices), as well as for diseases (Anguillicola infestation; bacterial infections). Total metal load significantly increased in eel liver tissue parallel to total length and body weight (log), while silvering females (W(B) > 200 g; L ≥ 500 mm) exhibited the highest amounts of Co, Cu, Hg, Se and Zn. Diverse effects may be expected in these big eels due to long-term metal exposure. In fact, IMBI (individual mean (multi-metal) bioaccumulation index) and copper load (…
Efficacy and tolerability of a fixed dose combination of cortex phospholipid liposomes and cyanocobalamin for intramuscular use in peripheral neuropa…
2019
Peripheral neuropathies are frequently encourtered in clinical practice and are assiociated with a major impairment in quality of life . Howewvwr, their management reamans poor, and current therapies are often burdened with major side effects and can present poor efficacy on pain and functionality. Therefore, it has been suggested that the combination of two or more different drugs may improve analgesis efficacy and reduce side effects. Tricortin 1000 is formulated with 12 mg of Brain cortex phospholipid liposomes + 1000 microgrammi of Cyanocobalamin injectable (PL+ CNCb1) for intramuscolar use and is indicated in the tratment of poly-algo-neuropathic syndromes. This combination exerts a ma…
Signal sequences modulate the immunogenic performance of human hepatitis C virus E2 gene
2005
Abstract Envelope protein E2 of human hepatitis C virus (HCV) is an attractive component of a prototype HCV vaccine. Delivered by DNA immunogens, E2 evokes specific immune response of Th1-type, failing to induce either considerable antibody production, or T-helper cell proliferation. We aimed at modulating the immunogenic performance of E2 gene by changing the mode of protein expression in eukaryotic cells. Plasmids were constructed encoding full-length E2 and nonstructural protein 1 (p7) fused to either 13 or 38 C-terminal amino acids (aa) of HCV E1 that contain second hydrophobic segment of E1 stop-transfer signal, or a complete E1 stop-transfer signal with duplicated second hydrophobic s…
Spinal analgesia for advanced cancer patients: An update
2011
In the nineties, spinal analgesia has been described as an useful means to control pain in advanced cancer patients. The aim of this review was to update this information with a systematic analysis of studies performed in the last 10 years. 27 papers pertinent with the topic selected for review were collected according to selection criteria. Few studies added further information on spinal analgesia in last decade. Despite a lack of a clinical evidence, spinal analgesia with a combination of opioids, principally morphine, and local anesthetics may allow to achieve analgesia in patients who had been intensively treated unsuccessfully with different trials of opioids. Some adjuvant drugs such …
Rains of Solitons in a Fiber Laser
2009
We report a novel and intriguing nonlinear dynamics observed in a fiber laser cavity, in which soliton pulses are created from an extended noisy background and drift until they reach a condensed phase comprising several tens of aggregated solitons. This soliton flow can be adjusted with manual cavity tuning, and can even be triggered by the injection of an external low-power cw laser.
Un mystère : la technique de conservation mise en oeuvre par Honoré Fragonard pour créer ses fameux écorchés
2008
A two part overview of the techniques used by Honoré Fragonard to create and preserve (mainly against the insects) cutaway anatomical figures (" écorchés ") of animals or humans. The first part summarise the techniques preparing the dry anatomical specimens at that time, according to contemporary bibliographical data: selection and preparation of the bodies, then injection of the various organs and tissues (e.g: muscles, nerves, lymph and blood vessels, placenta etc.). The second one gives detailed information on the techniques used by Fragonard to create his " écorchés " : selection of the subjects, highlighting the various organs and tissues, mummification, drying and varnishing. This new…
Regulatory sequences driving expression of the sea urchin Otp homeobox gene in oral ectoderm cells.
2005
Abstract PlOtp (Orthopedia), a homeodomain-containing transcription factor, has been recently characterized as a key regulator of the morphogenesis of the skeletal system in the embryo of the sea urchin Paracentrotus lividus . Otp acts as a positive regulator in a subset of oral ectodermal cells which transmit short-range signals to the underlying primary mesenchyme cells where skeletal synthesis is initiated. To shed some light on the molecular mechanisms involved in such a process, we begun a functional analysis of the cis -regulatory sequences of the Otp gene. Congruent with the spatial expression profile of the endogenous Otp gene, we found that while a DNA region from −494 to +358 is s…
Functional characterization of the enhancer blocking element of the sea urchin early histone gene cluster reveals insulator properties and three esse…
2000
Insulator elements can be functionally identified by their ability to shield promoters from regulators in a position-dependent manner or their ability to protect adjacent transgenes from position effects. We have previously reported the identification of a 265 bp sns DNA fragment at the 3' end of the sea urchin H2A early histone gene that blocked expression of a reporter gene in transgenic embryos when placed between the enhancer and the promoter. Here we show that sns interferes with enhancer-promoter interaction in a directional manner. When sns is placed between the H2A modulator and the inducible tet operator, the modulator is barred from interaction with the basal promoter. However, th…
A comparison of injection pain with articaine with adrenaline, prilocaine with phenylpressin and lidocaine with adrenaline
2008
Kutuk, Nukhet/0000-0001-6563-1899 WOS: 000259667200006 PubMed: 18587306 Objective: The objective of the present study was to investigate the pain on injection of articaine with adrenaline, prilocaine with phenylpressin, and lidocaine with adrenaline. Study Design: The study sample was comprised of 497 consecutively seen patients received 497 maxillary buccal infiltration injections or inferior alveolar block injections of 4% articaine with 1: 200.000 adrenaline, 3% prilocaine with 1.08mcg phenylpressin, or 2% lidocaine with 1: 100.000 adrenaline. Immediately after the injection, patients were asked to rate their injection pain on a six-point scale. Results: There were no significant differe…