Search results for "Interaction"

showing 10 items of 5710 documents

The hedgehog receptor patched is involved in cholesterol transport.

2011

International audience; BACKGROUND: Sonic hedgehog (Shh) signaling plays a crucial role in growth and patterning during embryonic development, and also in stem cell maintenance and tissue regeneration in adults. Aberrant Shh pathway activation is involved in the development of many tumors, and one of the most affected Shh signaling steps found in these tumors is the regulation of the signaling receptor Smoothened by the Shh receptor Patched. In the present work, we investigated Patched activity and the mechanism by which Patched inhibits Smoothened. METHODOLOGY/PRINCIPAL FINDINGS: Using the well-known Shh-responding cell line of mouse fibroblasts NIH 3T3, we first observed that enhancement …

ciliumlcsh:MedicineyeastBiochemistryReceptors G-Protein-CoupledTransmembrane Transport ProteinsMicechemistry.chemical_compound0302 clinical medicineMolecular Cell Biology[SDV.IDA]Life Sciences [q-bio]/Food engineeringMembrane Receptor SignalingBiomacromolecule-Ligand InteractionsSonic hedgehoglcsh:ScienceComputingMilieux_MISCELLANEOUS0303 health sciencesMultidisciplinaryMechanisms of Signal TransductionVeratrum Alkaloids[SDV.IDA] Life Sciences [q-bio]/Food engineeringdrosophilaSmoothened ReceptorLipidsHedgehog signaling pathwayCell biologySterolsSmoothened ReceptorAlimentation et Nutritionembryonic structurescilMembranes and Sorting[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]Signal transductionvesicular traffickingSignal TransductionResearch Articleprimary ciliumPatched ReceptorsPatchedsignal-transductionanimal structuresCyclopamine[SPI.GPROC] Engineering Sciences [physics]/Chemical and Process EngineeringBiophysicsReceptors Cell Surfacepathway activationSaccharomyces cerevisiaetransduction du signalBiology03 medical and health sciencessonic hedgehoglipidAnimalsHumansFood and NutritionHedgehog Proteins[SPI.GPROC]Engineering Sciences [physics]/Chemical and Process EngineeringBiology030304 developmental biologyPatched Receptorsprotein signalsCell Membranelcsh:RProteinscholesterolBiological TransportTransmembrane Proteinssterol-sensing domainchemistry[ SDV.NEU ] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]NIH 3T3 Cellscholesterol;lipid;cell trafficking; yeast;drosophila;cells ; pathway activation; vesicular trafficking; signal-transduction; sonic hedgehog;sterol-sensing domain; primary cilium;protein signalsbiology.proteincellslcsh:Qcell traffickingSmoothened030217 neurology & neurosurgery
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Prácticas docentes, condiciones de enseñanza y posibilidades de aprendizaje inicial de la lengua escrita

2012

El objetivo de este trabajo es explorar la relación entre las prácticas utilizadas por los docentes para enseñar a leer y a escribir en el inicio de la escolaridad y las oportunidades de aprendizaje. Se realiza un análisis cualitativo de una serie de tareas !levadas a cabo en aulas donde desarrollan tres tipos de prácticas diferentes -instruccionales, multidimensionales y sítuacionales-. Los resultados muestran que estas prácticas difieren en cuanto al tipo de tareas llevadas a cabo; en cuanto a las dinámicas desarrolladas para !levar/as a cabo; en cuanto a los contenidos de lectura y escritura trabajados y en cuanto a los materiales utilizados. Muestran, asimismo, que determinados rasgos q…

classroom analysisCultural Studiesenseñanza lengua escritainteraction classroom practicesComputingMilieux_COMPUTERSANDEDUCATIONLlenguatge i llengües EnsenyamentEnseñanza lengua escrita interacción prácticas docentes análisis de situaciones de aula.UNESCO::PEDAGOGÍAanálisis de situaciones de aulaprácticas docentesliteracy teachinginteracciónEducation
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Different student-strategies for interactional power in the IRF pattern in an EFL classroom

2007

classroom discoursevuorovaikutusluokkayhteisöstudent's powerEFLclassroom interactioninteractional and institutional powerIRF patternopettajatoppilaatopettaja-oppilassuhdevalta
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Introduzione al volume "Interaktion im Fremdsprachenunterricht"

2017

classroom interaction analysis della conversation multimodal analysis
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Restricted Neighborhood search clustering revisited: an evolutionary computation perspective

2013

clustering analysisprotein-protein interaction network
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Macro-micro relationship in nanostructured functional composites

2012

This paper examines the results of the characterization of two functional composites: Poly(methyl methacrylate) (PMMA)-Ce:YAG (yttrium aluminium garnet doped with cerium) and PMMA-cobalt hexacyanoferrate (CoHCF). The composites were prepared as possible emitters in the fields of lighting thermal sensors. The prepared composites were char- acterized using transmission electron microscopy (TEM), nuclear magnetic resonance (NMR) spectroscopy, thermogravi- metric analysis (TGA), differential scanning calorimetry (DSC) and dynamic mechanical analysis (DMA) analyses to study the correlation between micro and macro characteristics. We found that the molecular interactions of the two different fill…

cobalt hexacyanoferrateMaterials sciencePolymers and PlasticsGeneral Chemical EngineeringComposite numberchemistry.chemical_elementlcsh:Chemical technologyNanocompositeschemistry.chemical_compoundDifferential scanning calorimetryYttrium aluminium garnetnanocomposites PMMA yttrium aluminium garnet doped with cerium (Ce:YAG) cobalt hexacyanoferrate (CoHCF) interfacial interactionlcsh:TA401-492Materials ChemistryCeYAGlcsh:TP1-1185Physical and Theoretical ChemistryComposite materialMethyl methacrylateSettore CHIM/02 - Chimica Fisicachemistry.chemical_classificationOrganic ChemistryPolymerDynamic mechanical analysisPMMACeriumchemistryTransmission electron microscopyYAG) cobalt hexacyanoferrate (CoHCF) interfacial interaction [nanocomposites PMMA yttrium aluminium garnet doped with cerium (Ce]lcsh:Materials of engineering and construction. Mechanics of materialsinterfacial interactionExpress Polymer Letters
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An experimental, behavioral, and chemical analysis of food limitations in mutualistic Crematogaster ant symbionts inhabiting Macaranga host plants

2023

Obligate mutualistic plant-ants are often constrained by their plant partner's capacity to provide resources. However, despite this limitation, some ant partners actively reject potential prey items and instead drop them from the plant rather than consuming them, leaving the ants entirely reliant on host plant-provided food, including that provided indirectly by the symbiotic scale insects that ants tend inside the plants. This dependency potentially increases the efficiency of these ants in defending their host. We hypothesize that if this ant behavior was beneficial to the symbiosis, prey rejection by ants would be observed across multiple plant host species. We also hypothesize that plan…

coccidproteomicsSettore AGR/11 - Entomologia Generale E ApplicataEcologybehaviorplant–herbivore interactionSettore BIO/03 - Botanica Ambientale E ApplicataGC–MSfood bodiemyrmecophyteisotopeEcology Evolution Behavior and SystematicsNature and Landscape Conservation
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Voluntary Imitation in Alzheimer’s Disease Patients

2016

International audience; Although Alzheimer's disease (AD) primarily manifests as cognitive deficits, the implicit sensorimotor processes that underlie social interactions, such as automatic imitation, seem to be preserved in mild and moderate stages of the disease, as is the ability to communicate with other persons. Nevertheless, when AD patients face more challenging tasks, which do not rely on automatic processes but on explicit voluntary mechanisms and require the patient to pay attention to external events, the cognitive deficits resulting from the disease might negatively affect patients' behavior. The aim of the present study was to investigate whether voluntary motor imitation, i.e.…

cognitionAgingbehaviorsCognitive Neurosciencemedia_common.quotation_subject[ SDV.MHEP.GEG ] Life Sciences [q-bio]/Human health and pathology/Geriatry and gerontologyInterpersonal communicationaction observationperceptionStimulus (physiology)frontotemporal dementiaApraxia050105 experimental psychologylcsh:RC321-571Developmental psychology03 medical and health sciences0302 clinical medicinevisuomotor integrationPerceptionmedicine0501 psychology and cognitive scienceslcsh:Neurosciences. Biological psychiatry. NeuropsychiatryOriginal Researchmedia_commonmechanismsmotor imitationAction observation; Alzheimer's disease; Motor imitation; Movement execution; Social interaction; Aging; Cognitive Neuroscience05 social sciencesapraxiasocial interactiontoolCognitionAlzheimer's diseasemedicine.diseaseSocial relation[ SDV.NEU ] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]movement executionmovementCognitive imitationPsychologyAlzheimer’s disease030217 neurology & neurosurgeryNeuroscienceFrontotemporal dementiaCognitive psychologyFrontiers in Aging Neuroscience
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Creative interpretation in web design experience

2017

Insight into how people mentally represent, and thus, make sense of visual designs is the key to understanding how people interact with technological devices. This paper presents a study in which participants were asked to write their interpretations of two webpage design examples, based on what they thought they would say and what would remain as a thought. The data comprised 80 3E templates (N = 40), a template allowing participants to express experiences through writing and drawing. Inductive data analysis through a phenomenological lens revealed that supposed mental and verbal representations concentrated on the following design properties: colors, themes, interface layout and quality, …

cognitionkognitioComputer sciencemedia_common.quotation_subjectinvolvementArts and Humanities (miscellaneous)Human–computer interactionWeb designluovuus0501 psychology and cognitive sciences050107 human factorscreativitymedia_commonmental representationosallistuminenCognitive scienceta113Interpretation (philosophy)05 social sciences050301 educationCognitionCreativityComputer Graphics and Computer-Aided Designvisual web designMental representationKey (cryptography)visuaalinen suunnittelu0503 education
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Impact of biotic and abiotic factors on bacterial virulence

2013

coincidental evolutionympäristötekijätvirulenssipathogensvirulence evolutionisäntälajitinfektiotpatogeenitbakteeritresistenssiresistancevirulenceravintotaudinaiheuttajatbacteriophageprotozoan predationimmuunivastepredaatiogenotype-environment interactioninfectionsgeneettiset tekijät
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