Search results for "Interaction"
showing 10 items of 5710 documents
Kuule minua
2019
L‐Aspartate as a high‐quality nitrogen source in Escherichia coli : Regulation of L‐aspartase by the nitrogen regulatory system and interaction of L‐…
2020
Escherichia coli uses the C4-dicarboxylate transporter DcuA for L-aspartate/fumarate antiport, which results in the exploitation of L-aspartate for fumarate respiration under anaerobic conditions and for nitrogen assimilation under aerobic and anaerobic conditions. L-Aspartate represents a high-quality nitrogen source for assimilation. Nitrogen assimilation from L-aspartate required DcuA, and aspartase AspA to release ammonia. Ammonia is able to provide by established pathways the complete set of intracellular precursors (ammonia, L-aspartate, L-glutamate, and L-glutamine) for synthesizing amino acids, nucleotides, and amino sugars. AspA was regulated by a central regulator of nitrogen meta…
Binding Properties and Stability of the Ras-Association Domain of Rap1-GTP Interacting Adapter Molecule (RIAM)
2012
The Rap1-GTP interacting adapter protein (RIAM) is an important protein in Rap1-mediated integrin activation. By binding to both Rap1 GTPase and talin, RIAM recruits talin to the cell membrane, thus facilitating talin-dependent integrin activation. In this article, we studied the role of the RIAM Ras-association (RA) and pleckstrin-homology (PH) domains in the interaction with Rap1. We found that the RA domain was sufficient for GTP-dependent interaction with Rap1B, and the addition of the PH domain did not change the binding affinity. We also detected GTP-independent interaction of Rap1B with the N-terminus of RIAM. In addition, we found that the PH domain stabilized the RA domain both in …
The Large Hadron–Electron Collider at the HL-LHC
2021
The Large Hadron-Electron Collider (LHeC) is designed to move the field of deep inelastic scattering (DIS) to the energy and intensity frontier of particle physics. Exploiting energy-recovery technology, it collides a novel, intense electron beam with a proton or ion beam from the High-Luminosity Large Hadron Collider (HL-LHC). The accelerator and interaction region are designed for concurrent electron-proton and proton-proton operations. This report represents an update to the LHeC's conceptual design report (CDR), published in 2012. It comprises new results on the parton structure of the proton and heavier nuclei, QCD dynamics, and electroweak and top-quark physics. It is shown how the LH…
Summary of Week VII
2018
International audience; Week VII of the INT program 2018 “Probing Nucleons and Nuclei in High Energy Collisions” was dedicated to topics at the interface of the electron-ion collider (EIC), heavy ion and proton-nucleus collisions. The EIC will provide complementary tools to investigate and constrain the initial state in HIC collisions, as well as transport properties of QCD matter which can be extracted from observables that are sensitive to final states interactions such as pt-broadening and energy loss. The contributed talks and discussions covered a variety of physics topics from saturation physics and the origin of multi-particle correlations in HIC to jet quenching and the strong coupl…
Improving nanoscale terahertz field localization by means of sharply tapered resonant nanoantennas
2020
Abstract Terahertz resonant nanoantennas have recently become a key tool to investigate otherwise inaccessible interactions of such long-wavelength radiation with nano-matter. Because of their high-aspect-ratio rod-shaped geometry, resonant nanoantennas suffer from severe loss, which ultimately limits their field localization performance. Here we show, via a quasi-analytical model, numerical simulations, and experimental evidence, that a proper tapering of such nanostructures relaxes their overall loss, leading to an augmented local field enhancement and a significantly reduced resonator mode volume. Our findings, which can also be extended to more complex geometries and higher frequencies,…
TAPERING RESONANT NANOANTENNAS FOR ENHANCED THz LIGHT – NANOMATTER INTERACTIONS
2020
Nel corso degli ultimi decenni la tecnologia terahertz (THz) è diventata un fruttuoso campo di ricerca grazie alla spinta ricevuta dal desiderio di sfruttarne le promettenti applicazioni in questa porzione dello spettro elettromagnetico. La biologia, la medicina e l’ingegneria sono soltanto alcuni dei settori che guardano con interesse alle ultime scoperte nella ricerca sulle onde THz. Questo enorme interesse nasce dalle peculiari proprietà di tali onde, come ad esempio: il carattere non ionizzante, l’opacità di svariati materiali solitamente trasparenti in altri intervalli di frequenze e per le potenziali ricadute positive nel campo della tecnologia dell’informazione. Una fra le applicazio…
Enregistrer les interactions au restaurant : atouts et contraintes d’un cadre expérimental
2013
Dans le cadre d’un travail de recherche en Analyse Conversationnelle (Sacks, 1992) traitant des dimensions linguistiques et multimodales des interactions entre le personnel de service et les clients lors d’un repas au restaurant, nous avons élaboré une partie de notre corpus dans un restaurant expérimental équipé d’un système d’enregistrement audio et vidéo. Dans cet article, nous exposerons comment ce dispositif a été utilisé pour la constitution de notre corpus afin de capter des données authentiques enregistrées dans leur contexte naturel de production.Grâce à l’analyse fine de deux extraits, nous montrerons que le dispositif technique à disposition dans cette structure ne peut pas être …
Human Enterovirus Group B Viruses Rely on Vimentin Dynamics for Efficient Processing of Viral Nonstructural Proteins.
2019
A virus needs the host cell in order to replicate and produce new progeny viruses. For this, the virus takes over the host cell and modifies it to become a factory for viral proteins. Irrespective of the specific virus family, these proteins can be divided into structural and nonstructural proteins. Structural proteins are the building blocks for the new progeny virions, whereas the nonstructural proteins orchestrate the takeover of the host cell and its functions. Here, we have shown a mechanism that viruses exploit in order to regulate the host cell. We show that viral protein synthesis induces vimentin cages, which promote production of specific viral proteins that eventually control apo…
No uniform associations between parasite prevalence and environmental nutrients
2014
The resource quality of the host has been shown to affect parasite transmission success, prevalence, and virulence. Seasonal availability of environmental nutrients alters density and stoichiometric quality (carbon–nutrient ratios) of both producers and consumers, suggesting that nutrient availability may drive fluctuations in parasite prevalence patterns observed in nature. We examined the interactions between the population dynamics of a keystone herbivore, Daphnia, and its parasites, and their associations with water nutrient concentrations, resource quantity and quality, and other environmental variables (temperature, pH, oxygen concentration) in a small lake, using general linear model…