Search results for "Interference"
showing 10 items of 573 documents
Demo abstract: Cross-technology TDMA synchronization using energy pattern beacons
2017
When different technologies use the same frequency bands in close proximity, the resulting interference typically results in performance degradation. Coexistence methods exist, but these are often technology specific and require technology specific interference detection methods. To remove the root cause of the performance degradation, devices should be able to negotiate medium access even when using different technologies. To this end, an architecture that allows cross-technology medium access by means of a Time Division Multiple Access (TDMA) scheme was devised. In order to achieve cross-technology synchronization, which is required for the TDMA solution, an energy pattern beacon is trans…
Cigarette smoke increases BLT2 receptor functions in bronchial epithelial cells: in vitro and ex vivo evidence
2013
Summary Leukotriene B4 (LTB4) is a neutrophil chemotactic molecule with important involvement in the inflammatory responses of chronic obstructive pulmonary disease (COPD). Airway epithelium is emerging as a regulator of innate immune responses to a variety of insults including cigarette smoke, the major risk factor for COPD. In this study we have explored whether cigarette smoke extracts (CSE) or soluble mediators present in distal lung fluid samples (mini-bronchoalveolar lavages) from smokers alter the expression of the LTB4 receptor 2 (BLT2) and peroxisome proliferator-activated receptor-α (PPAR-α) in bronchial epithelial cells. We also evaluated the effects of CSE on the expression of i…
HSP27 controls GATA-1 protein level during erythroid cell differentiation.
2010
AbstractHeat shock protein 27 (HSP27) is a chaperone whose cellular expression increases in response to various stresses and protects the cell either by inhibiting apoptotic cell death or by promoting the ubiquitination and proteasomal degradation of specific proteins. Here, we show that globin transcription factor 1 (GATA-1) is a client protein of HSP27. In 2 models of erythroid differentiation; that is, in the human erythroleukemia cell line, K562 induced to differentiate into erythroid cells on hemin exposure and CD34+ human cells ex vivo driven to erythroid differentiation in liquid culture, depletion of HSP27 provokes an accumulation of GATA-1 and impairs terminal maturation. More spec…
eNOS S-nitrosylates β-actin on Cys374 and regulates PKC-θ at the immune synapse by impairing actin binding to profilin-1.
2017
The actin cytoskeleton coordinates the organization of signaling microclusters at the immune synapse (IS); however, the mechanisms involved remain poorly understood. We show here that nitric oxide (NO) generated by endothelial nitric oxide synthase (eNOS) controls the coalescence of protein kinase C-¿ (PKC-¿) at the central supramolecular activation cluster (c-SMAC) of the IS. eNOS translocated with the Golgi to the IS and partially colocalized with F-actin around the c-SMAC. This resulted in reduced actin polymerization and centripetal retrograde flow of ß-actin and PKC-¿ from the lamellipodium-like distal (d)-SMAC, promoting PKC-¿ activation. Furthermore, eNOS-derived NO S-nitrosylated ß-…
New circuital models of grounding systems and PDS for EMI analysis during a lightning strike
2005
In this paper circuital models of a Power Drive System (PDS) and of grounding systems are proposed in order to analyse Electromagnetic Interferences (EMI) induced in a PDS when a lightning current flows in the grounding system. The models have been developed adopting the network approach with lumped parameters and have been implemented using the software MATLAB. A High Frequency (HF) model suitable to simulate the impulse response of a PDS is described and a generalized method in order to calculate the lumped parameters values of grounding system models is presented. The new method takes into account the burial depth of electrodes as regards their length. The validation results of this new …
Resveratrol decreases the levels of miR-155 by upregulating miR-663, a microRNA targeting JunB and JunD.
2010
An inflammatory component is present in the microenvironment of most neoplastic tissues, including those not causally related to an obvious inflammatory process. Several microRNAs, and especially miR-155, play an essential role in both the innate and adaptative immune response. Resveratrol (trans-3,4#,5-trihydroxystilbene) is a natural antioxidant with anti-inflammatory properties that is currently at the stage of preclinical studies for human cancer prevention. Here, we establish that, in human THP-1 monocytic cells as well as in human blood monocytes, resveratrol upregulates miR- 663, a microRNA potentially targeting multiple genes implicated in the immune response. In THP-1 cells, miR-66…
Impact of LoRa Imperfect Orthogonality: Analysis of Link-Level Performance
2018
In this letter, we focus on the evaluation of link-level performance of LoRa technology, in the usual network scenario with a central gateway and high-density deployment of end-devices. LoRa technology achieves wide coverage areas, low power consumption and robustness to interference thanks to a chirp spread-spectrum modulation, in which chirps modulated with different spreading factors (SFs) are quasi-orthogonal. We focus on the performance analysis of a single receiver in presence of collisions. First, we analyze LoRa modulation numerically and show that collisions between packets modulated with different SFs can indeed cause packet loss if the interference power received is strong enough…
LoRa Technology Demystified: From Link Behavior to Cell-Level Performance
2020
In this paper we study the capability of LoRa technology in rejecting different interfering LoRa signals and the impact on the cell capacity. First, we analyze experimentally the link-level performance of LoRa and show that collisions between packets modulated with the same Spreading Factor (SF) usually lead to channel captures, while different spreading factors can indeed cause packet loss if the interference power is strong enough. Second, we model the effect of such findings to quantify the achievable capacity in a typical LoRa cell: we show that high SFs, generally seen as more robust, can be severely affected by inter-SF interference and that different criteria for deciding SF allocati…
A Green Mesh Routers' Placement to Ensure Small Cells Backhauling in 5G Networks
2017
International audience; The wireless industry is preparing the fifth generation wireless systems with several requirements regarding capacity and coverage area. A promising solution to meet this challenge is a densification of the network via a large scale deployment of small cells from different sizes. The advantage here is that small cells are easy to deploy and cost-efficient compared to macro base stations. However, the challenge is to ensure a reliable backhaul links. Mesh routers backhauling is one of the candidate solutions here, since it is easy to deploy, doesn't use wired connections between locations and cost-efficient. Nevertheless, the issue is to deploy routers in the suitable…
Transcription factor NRF2 regulates miR-1 and miR-206 to drive tumorigenesis
2013
The mechanisms by which deregulated nuclear factor erythroid-2–related factor 2 (NRF2) and kelch-like ECH-associated protein 1 (KEAP1) signaling promote cellular proliferation and tumorigenesis are poorly understood. Using an integrated genomics and 13C-based targeted tracer fate association (TTFA) study, we found that NRF2 regulates miR-1 and miR-206 to direct carbon flux toward the pentose phosphate pathway (PPP) and the tricarboxylic acid (TCA) cycle, reprogramming glucose metabolism. Sustained activation of NRF2 signaling in cancer cells attenuated miR-1 and miR-206 expression, leading to enhanced expression of PPP genes. Conversely, overexpression of miR-1 and miR-206 decreased the exp…