Search results for "Intraocular"
showing 10 items of 447 documents
Aseptic Production vs. Terminal Sterilization
2000
The safety of substance use in intraocular surgery ideally requires the absence of all biologically-active components capable of causing an inflammatory reaction. Substance purity is achieved with isolation and cleansing methods (e.g., of the polysaccharide), which remove any biological component with infective potential. The methods of production for polysaccharide isolation should remove biological agents, regardless of its origin. Hyaluronic acid is isolated either from rooster combs or biological fermentation. Use of this substance showed the development of postoperative intraocular inflammatory reactions resulting from contaminations from both sources. OVD should have low endotoxin val…
Possible involvement of nitric oxide in morphine-induced miosis and reduction of intraocular pressure in rabbits.
2006
The role of μ3 opioid receptors in morphine-induced intraocular pressure (IOP) lowering effect and miosis was evaluated in conscious, dark-adapted New Zealand white (NZW) rabbits using a masked-design study. IOP and pupil diameter (PD) measurements were taken at just before and 0.5, 1, 2, 4, 6 h after monolateral instillation of morphine (10, 50 and 100 μg/30 μl) as compared to vehicle administered in the contralateral eye. Morphine-induced ocular effects were challenged by a pre-treatment with the non-selective opioid receptor antagonist, naloxone (100 μg/30 μl), the nitric oxide synthase inhibitor, Nω-nitro-l-arginine methyl ester (l-NAME, 1%, 30 μl), or the non-selective μ3 opioid recept…
Retinal straylight in patients with monofocal and multifocal intraocular lenses
2007
Purpose To determine the differences in retinal straylight perceived by patients with monofocal intraocular lenses (IOLs) and patients with multifocal IOLs. Setting Vissum-Instituto de Oftalmologico de Alicante, Alicante, Spain. Methods In this prospective study, contrast sensitivity and retinal straylight were measured prospectively 6 months postoperatively in 67 eyes of 40 patients with a monofocal or multifocal IOL. In the monofocal group, a ThinOptX IOL (ThinOptX, Inc.) was implanted in 12 eyes and an Acri.Smart 48 S IOL (Acri.Tec) in 20 eyes. In the multifocal IOL group, a ReZoom IOL (Advanced Medical Optics) was implanted in 13 eyes and a ReSTOR IOL (Alcon Laboratories) in 22 eyes. Re…
Imaging quality of multifocal intraocular lenses: automated assessment setup
2012
[EN] Purpose: A new technique for the assessment of the optical quality of multifocal intraocular lenses (MIOLs) under monochromatic and polychromatic illumination is presented. Methods: The system provides, in a totally automated procedure, the modulation transfer function (MTF) of the lens under test for different axial positions of the object. The artificial eye admits different artificial corneas, to optimise the axial resolution in the sampling of the MTF of the MIOL under test, and different pupils, to test the dependence of the optical performance of the MIOL on the eye pupil diameter. Results: The performance and sensitivity of the apparatus is tested with different commercial MIOLs…
Deliberate Arterial Hypotension Does Not Reduce Intraocular Pressure in Pigs
1992
Among the accepted advantages of general anesthesia in ophthalmic surgery is improved control of intraocular pressure (IOP). Although standard textbooks advocate deliberate arterial hypotension to facilitate intraocular surgery by reducing IOP, scientific proof of such an effect is lacking. The authors investigated effects of induced arterial hypotension on IOP in an anesthetized porcine model. Forty-two piglets were anesthetized with piritramide, were placed in the prone position, and had the anterior chamber of one eye punctured with a small Teflon cannula to measure IOP. Six pigs were used in a pilot study to establish dose-response relationships for the hypotensive agents; 36 pigs were …
Topical glaucoma medications – Clinical implications for the ocular surface
2022
Glaucoma is a leading cause of irreversible blindness. The use of topical eye drops to reduce intraocular pressure remains the mainstay treatment. These eye drops frequently contain preservatives designed to ensure sterility of the compound. A growing number of clinical and experimental studies report the detrimental effects of not only these preservatives but also the active pharmaceutical compounds on the ocular surface, with resultant tear film instability and dry eye disease. Herein, we critically appraise the published literature exploring the effects of preservatives and pharmaceutical compounds on the ocular surface. publishedVersion
Optical performance of two new trifocal intraocular lenses: through-focus modulation transfer function and influence of pupil size
2013
Background To compare the in vitro optical quality of two new trifocal intraocular lenses at different focal points as a function of pupil size. Methods Two intraocular lenses having different design approaches were evaluated: the AT LISA tri 839MP with a trifocal diffractive design, and the FineVision, which combines two distinct apodized bifocal diffractive profiles resulting in three foci. A PMTF optical bench was used to assess the intraocular lenses' performance, and as optical quality metrics, the through-focus modulation transfer function was selected; that is, it was measured at 10 focal points and for four different apertures (2.0, 3.0, 3.75 and 4.5 mm). Results For both lenses, th…
Comparison of the Ultraviolet Light Filtering across Different Intraocular Lenses.
2018
SIGNIFICANCE We have analyzed the ultraviolet transmittance of some commercial intraocular lenses (IOLs). The results show differences of wavelength cutoff among them. PURPOSE The purpose of this study was to measure and compare the ultraviolet light transmittance of different IOLs made out of acrylic hydrophobic, hydrophilic, and hydrophilic with hydrophobic surface materials from different manufacturers. METHODS The spectral transmission curves of eight monofocal IOLs with the same dioptric power of +20.0 diopters were measured using a PerkinElmer Lambda 35 ultraviolet/visible spectrometer. Two IOLs of each type were tested three times. The ultraviolet cutoff wavelength at 10% transmissio…
Photoprotection and photoreception of intraocular lenses under xenon and white LED illumination.
2016
Objective. To analyze the photoprotection and phototransmission that various intraocular lenses (10Ls) provide under the illumination of a xenon (Xe) lamp and white LEDs (light emitting diode). Methods. The spectral transmission curves of six representative 10Ls were measured using a Perkin-Elmer Lambda 35 UV/VIS spectrometer. Various filtering simulations were performed using a Xe lamp and white LEDs. The spectral emissions of these lamps were measured with an ILT-950 spectroradiometer. Results. The 10Ls analyzed primarily show transmission of nearly 100% in the visible spectrum. In the ultraviolet (UV) region, the filters incorporated in the various 10Ls did not filter equally, and some o…
In vitro optical quality comparison of 2 trifocal intraocular lenses and 1 progressive multifocal intraocular lens.
2015
Purpose To evaluate the optical quality of 3 multifocal intraocular lenses (IOLs): the Mini Well Ready progressive multifocal aspheric IOL, the AT LISA trifocal diffractive IOL, and the Finevision full diffractive trifocal IOL. Setting University of Valencia, Valencia, Spain. Design Experimental study. Methods An instrument designed for measuring real-time modulation transfer function (MTF) and IOL power was used to measure the optical quality of each IOL for 3.0 mm and 4.5 mm apertures. This instrument measures both sagittal and tangential MTFs. The optical quality of each IOL was evaluated with the MTF, through-focus MTF, defocus tolerance, Strehl ratio MTF, and relative percentage of lig…