Search results for "L-lactate"

showing 10 items of 93 documents

Changes in Salivary Levels of Creatine Kinase, Lactate Dehydrogenase, and Aspartate Aminotransferase after Playing Rugby Sevens: The Influence of Gen…

2020

Rugby sevens is characterised by continuous exertion and great physical contact per unit of time, leading to muscle damage. It is important to identify markers that can quantify muscle damage in order to improve recovery strategies. The objective of this study was to evaluate the release dynamics of muscle damage markers creatine kinase (CK), lactate dehydrogenase (LDH), and aspartate aminotransferase (AST) in saliva samples when playing rugby sevens, analysing the influence of gender, during the rugby sevens university championship of Spain. The total sample included 27 athletes, divided into two teams of 14 men and 13 women between 18 and 31 years of age. CK, LDH, and AST were quantified …

AdultMaleSalivaAdolescentHealth Toxicology and MutagenesisFootballlcsh:MedicinePhysiologyPerceived exertionMuscle damageArticle03 medical and health scienceschemistry.chemical_compoundYoung Adult0302 clinical medicinemuscle damageaspartate aminotransferaseLactate dehydrogenasegenderMedicineHumansrugby sevensExertionAspartate AminotransferasesSalivabiologyL-Lactate DehydrogenaseAthletesbusiness.industrycreatine kinaselcsh:RPublic Health Environmental and Occupational Healthlactate dehydrogenase030229 sport sciencesbiology.organism_classificationchemistrySpainbiology.proteinCreatine kinaseFemalebusiness030217 neurology & neurosurgeryInternational journal of environmental research and public health
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Effects of α-tocopherol, β-carotene and ascorbic acid on oxidative, hormonal and enzymatic exercise stress markers in habitual training activity of p…

2001

Background Intense physical exercise has been associated with an increase of free radical production. When the body's natural defense systems against free radicals are overwhelmed, oxidative stress increases. Aim of the study This study examined the effects of a vitamin antioxidant supplement, (composed of 600 mg α-tocopherol, 1000 mg ascorbic acid and 32 mg β-carotene) on oxidative, hormonal, and enzymatic exercise stress markers during habitual training activity over 35 days. Methods The plasma concentrations of ascorbic acid, α-tocopherol, β-carotene, testosterone, cortisol and lipid peroxides and the serum activities of lactate dehydrogenase and creatine kinase were measured at four tim…

AdultMaleVitaminmedicine.medical_specialtyAntioxidantHydrocortisoneAnabolismmedicine.medical_treatmentalpha-TocopherolMedicine (miscellaneous)Ascorbic AcidBasketballmedicine.disease_causeAntioxidantsLipid peroxidationchemistry.chemical_compoundInternal medicineLactate dehydrogenasemedicineHumansSingle-Blind MethodTestosteroneCreatine KinaseExerciseNutrition and DieteticsL-Lactate Dehydrogenasebeta CaroteneAscorbic acidOxidative StressEndocrinologychemistryDietary SupplementsLipid Peroxidationalpha-TocopherolOxidation-ReductionOxidative stressEuropean Journal of Nutrition
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Mechanism of Free Radical Production in Exhaustive Exercise in Humans and Rats; Role of Xanthine Oxidase and Protection by Allopurinol

2000

Exhaustive exercise generates free radicals, However, the source of this oxidative damage remains controversial. The aim of this paper was to study further the mechanism of exercise-induced production of free radicals, Testing the hypothesis that xanthine oxidase contributes to the production of free radicals during exercise, me found not only that exercise caused an increase in blood xanthine oxidase activity in rats but also that inhibiting xanthine oxidase with allopurinol prevented exercise-induced oxidation of glutathione in both rats and in humans. Furthermore, inhibiting xanthine oxidase prevented the increases in the plasma activity of cytosolic enzymes (lactate dehydrogenase, aspar…

AdultMaleXanthine OxidaseFree RadicalsAllopurinolPhysical ExertionClinical BiochemistryAllopurinolOxidative phosphorylationallopurinolPharmacologyMitochondrionmedicine.disease_causeBiochemistrychemistry.chemical_compoundphysical exerciseMalondialdehydeGeneticsmedicineoxidative stressAnimalsHumansAspartate AminotransferasesEnzyme InhibitorsRats WistarMuscle SkeletalXanthine oxidaseCreatine KinaseExerciseMolecular BiologyOxidase testL-Lactate DehydrogenaseFree Radical ScavengersCell BiologyGlutathioneXanthineGlutathioneMitochondriaRatsOxidative StressLiverchemistryBiochemistryxanthine oxidaseOxidative stressmedicine.drugIUBMB Life (International Union of Biochemistry and Molecular Biology: Life)
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Skeletal muscle fibre types, enzyme activities and physical performance in young males and females

1978

Differences in skeletal muscle characteristics, metabolic profiles and functional performance between males and females were investigated using young (15--24 yrs) male and female twins as subjects. The comparison included such variables as anthropometry, muscle strength, mechanical power, maximum oxygen uptake, electrical activation of muscle, muscle fibre composition (m. vastus lateralis), and activities of several skeletal muscle enzymes. The results disclosed the following primary differences between males and females: In the various functional tests the performance of females was from 61.1 to 84.6% of that in males; distribution of slow twitch fibres in m. vastus lateralis of the female…

AdultMalemedicine.medical_specialtyContraction (grammar)AdolescentPhosphorylasesPhysiologyATPasePhysical ExertionTwinsIsometric exerciseBiologyIsozymeGlycogen phosphorylaseOxygen ConsumptionSex FactorsHeart RatePregnancyHexokinaseInternal medicinemedicineHumansGlycolysisCreatine KinaseAdenosine TriphosphatasesL-Lactate DehydrogenaseMusclesAdenylate KinaseSkeletal muscleVO2 maxIsoenzymesmedicine.anatomical_structureEndocrinologyPhysical FitnessLactatesbiology.proteinFemaleMuscle ContractionActa Physiologica Scandinavica
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Assessment of induced corneal hypoxia in diabetic patients

2002

Comparative Study Address correspondence and reprint requests to Dr. C. Creuzot-Garcher, Service d'Ophtalmologie, CHU, Hopital Général, 3 Rue du Faubourg Raines, BP 1519, 21033 Dijon, France. E-mail: Catherine.creuzot-garcher@chu-dijon.fr; To assess the control of corneal hydration in patients with diabetes during a contact lens-induced hypoxia. Corneal stress was induced in 15 patients with diabetes and 23 healthy patients by having them wear contact lenses for 2 hours. Pachymetries were measured and corneal parameters (percentage recovery per hour [PRPH], time for deswelling [T99%] and induced swelling [IS]) were calculated. In the mean time, tears were collected to assess the activity of…

AdultMalemedicine.medical_specialtyPathologyCell CountCorneachemistry.chemical_compoundStress PhysiologicalOphthalmologyLactate dehydrogenaseDiabetes mellitusHumansMedicineIn patient[SDV.MHEP.OS]Life Sciences [q-bio]/Human health and pathology/Sensory OrgansHypoxiaAged[SDV.MHEP] Life Sciences [q-bio]/Human health and pathologyL-Lactate Dehydrogenasebusiness.industryCorneal EdemaEndothelium CornealMiddle AgedHypoxia (medical)Contact Lenses Hydrophilicmedicine.diseaseeye diseasesOphthalmologyDiabetes Mellitus Type 1Diabetes Mellitus Type 2chemistry[SDV.MHEP.OS] Life Sciences [q-bio]/Human health and pathology/Sensory OrgansTearsTearsFemaleCorneal hypoxiasense organsmedicine.symptomSwellingbusinessAnaerobic exercise[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
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Soluble intercellular adhesion molecule-1 (s-ICAM-1/s-CD54) in diffuse large B-cell lymphoma: association with clinical characteristics and outcome

2003

Background: High serum levels of soluble intercellular adhesion molecule-1(s-ICAM-1/s-CD54) have been associated with adverse clinical features and poor outcome in chronic lymphocytic leukemia, Hodgkin’s disease and non-Hodgkin’s lymphoma, but their value in the different subtypes of non-Hodgkin’s lymphoma has not been well addressed. Patients and methods: Our aim was to study the serum levels of s-ICAM-1 in diffuse large B-cell lymphoma (DLBCL) and to correlate them with clinical characteristics and outcome. We analyzed the serum levels of s-ICAM-1 in a series of 55 patients with DLBCL diagnosed in a single institution. s-ICAM-1 levels were quantified by an immunoenzymatic assay. Median ag…

AdultMalemedicine.medical_specialtyPathologyLymphoma B-CellChronic lymphocytic leukemiaGastroenterologyImmunoenzyme TechniquesInternational Prognostic IndexRisk Factorshemic and lymphatic diseasesInternal medicineAntineoplastic Combined Chemotherapy ProtocolsBiomarkers TumormedicineHumansSurvival analysisAgedAged 80 and overL-Lactate DehydrogenaseBeta-2 microglobulinbusiness.industryLymphoma Non-HodgkinLarge-cell lymphomaHematologyMiddle AgedIntercellular Adhesion Molecule-1Prognosismedicine.diseaseSurvival AnalysisLymphomaTreatment OutcomeOncologyB symptomsCase-Control StudiesLymphatic MetastasisDisease ProgressionFemaleLymphoma Large B-Cell Diffusemedicine.symptombusinessDiffuse large B-cell lymphomaAnnals of Oncology
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Adropin and apelin fluctuations throughout a season in professional soccer players: Are they related with performance?

2015

Myokines are likely to be involved in the whole-body metabolic adaptive changes that occur in response to regular exercise. We aimed to investigate the association of the two myokines (adropin and apelin) with physical performance in professional soccer players. To this purpose, we analyzed the fluctuations of circulating levels of both adropin and apelin in professional soccer players during a season and evaluated the possible association of these myokines with the performance level. Creatine kinase (CK) and lactate dehydrogenase (LDH) activity as well as iron, transferrin and high-sensitivity C-Reactive protein (hsCRP), ferritin, soluble transferrin receptor (sTfR), free testosterone/cort…

AdultMalemedicine.medical_specialtyPhysiologyIronBiochemistryYoung AdultCellular and Molecular NeuroscienceEndocrinologyTotal iron-binding capacityRegular exerciseInternal medicineSoccerMyokinemedicineHumansCreatine KinaseExerciseSoluble transferrin receptorchemistry.chemical_classificationL-Lactate Dehydrogenasebiologymedicine.diagnostic_testbusiness.industryBlood ProteinsApelinFerritinC-Reactive ProteinEndocrinologychemistryTransferrinFerritinsbiology.proteinApelinIntercellular Signaling Peptides and ProteinsCreatine kinaseSeasonsPeptidesbusinesshuman activitiesPeptides
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Enzyme activities in muscle and connective tissue of M. vastus lateralis in habitually training and sedentary 33 to 70-year-old men

1975

A cross-sectional study was carried out to examine the activities of certain enzymes representing aerobic and anaerobic energy metabolism as well as the biosynthesis of collagen of M. vastus lateralis in 23 male endurance athletes in habitual training, aged 33 to 70 years. 23 sedentary healthy men of corresponding ages were selected for the control group. The mean maximal oxygen uptake of the trained subjects was 53.6 ml · kg−1 · min−1 and that of the control subjects 36.3 ml · kg−1 · min−1. As compared to the control group the trained subjects had significantly higher values in the muscle malate dehydrogenase, succinate dehydrogenase and prolyl hydroxylase activities, whereas the opposite …

AdultMalemedicine.medical_specialtyPhysiologyPhysical ExertionProcollagen-Proline DioxygenaseConnective tissueMalate dehydrogenasechemistry.chemical_compoundOxygen ConsumptionMalate DehydrogenaseEndurance trainingHexokinasePhysiology (medical)Internal medicineLactate dehydrogenasemedicineHumansOrthopedics and Sports MedicineCreatine KinaseAgedPhysical Education and TrainingL-Lactate DehydrogenasebiologyMusclesPublic Health Environmental and Occupational HealthVO2 maxSkeletal muscleGeneral MedicineMiddle AgedSuccinate DehydrogenaseEndocrinologymedicine.anatomical_structurechemistrybiology.proteinCreatine kinaseCollagenEnergy MetabolismAnaerobic exerciseSportsEuropean Journal of Applied Physiology and Occupational Physiology
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Lipid metabolism during exercise I: Physiological and biochemical characterization of normal healthy male subjects in relation to their physical fitn…

1978

On the basis of maximal oxygen uptake (\(\dot V\)O2 max) 18 normal, healthy men were divided into two groups of equal size: moderately trained subjects (MTR) each having \(\dot V\)O2 max below 65.0 ml·min−1·kg−1 body weight (54.0±8.3) and well trained subjects (WTR), whose \(\dot V\)O2 max exceeded 65.0 ml·min−1·kg−1 body weight (69.2±4.1). The WTR group had slightly (non significant, n.s.) higher percentage of slow twitch, oxidative (SO) fibers in M. vastus lateralis and higher (n.s.) activities of cytochrome c oxidase (CytOx), succinate dehydrogenase (SDH), 3-hydroxyacyl-CoA-dehydrogenase (HADH), and citrate synthase (CS), while lactate dehydrogenase (LDH) activity was lower (n.s.). In th…

AdultMalemedicine.medical_specialtyPhysiologyPhysical fitnessCitrate (si)-SynthaseOxidative phosphorylationBiologyModels BiologicalElectron Transport Complex IVchemistry.chemical_compoundOxygen ConsumptionPhysiology (medical)Internal medicineLactate dehydrogenasemedicineHumansCytochrome c oxidaseCitrate synthaseOrthopedics and Sports MedicineL-Lactate Dehydrogenasebusiness.industryMusclesSuccinate dehydrogenasePublic Health Environmental and Occupational Health3-Hydroxyacyl CoA DehydrogenasesOxo-Acid-LyasesVO2 maxGeneral MedicineSuccinate DehydrogenaseEndocrinologyBiochemistrychemistryPhysical Fitnessbiology.proteinLean body massOxidoreductasesbusinessEuropean Journal of Applied Physiology and Occupational Physiology
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The week after running a marathon: Effects of running vs elliptical training vs resting on neuromuscular performance and muscle damage recovery

2021

Our aim was to compare the effects of two exercise modalities vs resting on the time course of neuromuscular performance and muscle damage recovery during the week after running a marathon. Sixty-four finishers from a road marathon completed the study (54 men and 10 women; 39 ± 4 years; 3 h 35 min ± 21 min). The day before the race, within 15 min after finishing the marathon and at 24, 48, 96, 144 and 192 h postrace, lactate dehydrogenase and creatine kinase were analysed. Participants also performed a squat jump (SJ) test before and after the marathon and at 48, 96 and 144 h postrace. On their arrival to the finish line, participants were randomized into one of the three intervention group…

AdultMalemedicine.medical_specialtyRestMarathon Running030209 endocrinology & metabolismPhysical Therapy Sports Therapy and RehabilitationMuscle damage03 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitationmedicineHumansOrthopedics and Sports MedicineMuscle SkeletalCreatine KinasemusculoskeletalL-Lactate Dehydrogenasebusiness.industryRecovery of Function030229 sport sciencesGeneral MedicineTime courseFemalefatiguebusinesshuman activitiesBiomarkersperformanceEuropean Journal of Sport Science
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