Search results for "LABOR"

showing 10 items of 3876 documents

In HCV-related liver cirrhosis, local pulse wave velocity increases and in decompensated patients correlates with poorer survival

2018

BackgroundCirrhotic cardiomyopathy (CCM) refers to cardiac dysfunction in patients with liver cirrhosis, in the absence of other known cardiac disease.MethodsControl group and patients diagnosed of liver cirrhosis without known cardiac disease or hepatocellular carcinoma were enrolled for this clinical observation study. Patients with diabetes mellitus, hypertension were excluded. Absolute global longitudinal strain, one-point carotid pulse wave velocity (one-point PWV) and various parameters were measured in resting status.ResultsThere were 29 participants in the control group and 80 patients in the liver cirrhosis group. 27.8% of cirrhotic patients presented with normal systolic but abnor…

Liver CirrhosisMaleRNA virusesCirrhosisEtiologySocial SciencesHepacivirus030204 cardiovascular system & hematologyMathematical and Statistical Techniques0302 clinical medicineMedicine and Health SciencesPsychologyCardiac OutputPulse wave velocityPathology and laboratory medicineMultidisciplinaryHepatitis C virusLiver DiseasesQStatisticsRHepatitis CMiddle AgedMedical microbiologyHepatitis CAddictsCirrhosisHepatocellular carcinomaVirusesPhysical SciencesCardiologyMedicineRegression AnalysisFemale030211 gastroenterology & hepatologyPathogensCardiomyopathiesResearch ArticleAdultHepatitis B virusmedicine.medical_specialtyDeath RatesScienceCardiologyDiastoleAddictionGastroenterology and HepatologyPulse Wave AnalysisResearch and Analysis MethodsMicrobiology03 medical and health sciencesPopulation MetricsInternal medicineDiabetes mellitusmedicineHumansAlcoholicsStatistical MethodsAgedHepatitisBiology and life sciencesFlavivirusesPopulation Biologybusiness.industryOrganismsViral pathogensmedicine.diseaseHepatitis virusesCirrhotic cardiomyopathyMicrobial pathogensbusinessMathematicsPLOS ONE
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Genetic variation in the TLL1 gene is not associated with fibrosis in patients with metabolic associated fatty liver disease.

2020

Metabolic associated fatty liver disease (MAFLD) is the most prevalent liver disease in Western nations, with high heritability. A recent study of Japanese patients with the disease suggested that TLL1 rs17047200 is associated with fibrosis; whether a similar association is observed in Caucasian patients with MAFLD is unknown. We investigated the association of the TLL1 rs17047200 polymorphism with liver fibrosis in a cohort of Caucasian patients with MAFLD (n = 728). We also investigated whether TLL1 expression is altered during liver injury in humans, in murine models of fibrosis, and in in-vitro. While TLL1 expression is upregulated in the liver of humans with MAFLD and in mice, the rs17…

Liver CirrhosisMaleSteatosisGene ExpressionDiseasePathology and Laboratory MedicineInbred C57BLGastroenterologyPathogenesisCytopathologyCohort StudiesLiver diseaseMice0302 clinical medicineFibrosisMedicine and Health SciencesLiver injury0303 health sciencesMultidisciplinaryLiver DiseasesQFatty liverRTLL1Single NucleotideMiddle Aged3. Good healthUp-RegulationAdult; Animals; Cohort Studies; Fatty Liver; Female; Genetic Variation; Humans; Liver Cirrhosis; Male; Mice; Mice Inbred C57BL; Middle Aged; Tolloid-Like Metalloproteinases; Up-Regulation; Polymorphism Single NucleotideMedicineLiver Fibrosis030211 gastroenterology & hepatologyFemaleAnatomyResearch ArticleAdultmedicine.medical_specialtyHistologyTolloid-Like MetalloproteinasesSettore MED/12 - GASTROENTEROLOGIAScienceGastroenterology and HepatologyPolymorphism Single Nucleotide03 medical and health sciencesInternal medicinemedicineGeneticsAnimalsHumansPolymorphism030304 developmental biologyNutritionbusiness.industryAdult Animals Cohort Studies Fatty Liver Female Genetic Variation Humans Liver Cirrhosis Male Mice Mice Inbred C57BL Middle Aged Tolloid-Like Metalloproteinases Up-Regulation Polymorphism Single NucleotideBiology and Life SciencesGenetic Variationmedicine.diseaseFibrosisDietFatty LiverMice Inbred C57BLn/aAnatomical PathologySteatosisbusinessDevelopmental Biology
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Performance of two HCV RNA assays during protease inhibitor-based triple therapy in patients with advanced liver fibrosis and cirrhosis.

2014

Introduction: On-treatment HCV RNA measurements are crucial for the prediction of a sustained virological response (SVR) and to determine treatment futility during protease inhibitor-based triple therapies. In patients with advanced liver disease an accurate risk/benefit calculation based on reliable HCV RNA results can reduce the number of adverse events. However, the different available HCV RNA assays vary in their diagnostic performance. Aim: To investigate the clinical relevance of concordant and discordant results of two HCV RNA assays during triple therapy with boceprevir and telaprevir in patients with advanced liver fibrosis/cirrhosis. Methods: We collected on-treatment samples of 1…

Liver CirrhosisViral DiseasesCirrhosisGastroenterology and hepatologyHepaciviruslcsh:MedicineHepacivirusmedicine.disease_causeGastroenterologyTelaprevirHepatitisLiver diseasechemistry.chemical_compoundMedicinelcsh:ScienceMultidisciplinarybiologyvirus diseasesHepatitis CHepatitis CClinical Laboratory SciencesEuropeClinical LaboratoriesInfectious hepatitisInfectious DiseasesTreatment OutcomeAnti-Retroviral AgentsHCVRNA ViralOligopeptidesmedicine.drugResearch Articlemedicine.medical_specialtyGenotypeProlineHepatitis C virusDiagnostic MedicinePredictive Value of TestsBoceprevirInternal medicineHumansProtease InhibitorsViremiaddc:610Liver diseasesMedicine and health sciencesbusiness.industryClinical Laboratory Techniqueslcsh:RRNAReproducibility of Resultsmedicine.diseasebiology.organism_classificationdigestive system diseaseschemistryImmunologylcsh:Qbusiness
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Collaborative Virtual Reality for Laparoscopic Liver Surgery Training

2019

Virtual reality (VR) has been used in many medical training systems for surgical procedures. However, the current systems are limited due to inadequate interactions, restricted possibilities of patient data visualization, and collaboration. We propose a collaborative VR system for laparoscopic liver surgical planning and simulation. Medical image data is used for model visualization and manipulation. Additionally, laparoscopic surgical joysticks are used to provide an opportunity for a camera assistant to cooperate with an experienced surgeon in VR. Continuous clinical feedback led us to optimize the visualization, synchronization, and interactions of the system. Laparoscopic surgeons were …

Liver surgery0209 industrial biotechnologygenetic structuresbusiness.industryComputer scienceComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISIONUsability02 engineering and technologyVirtual realitySurgical planningVisualization020901 industrial engineering & automationHuman–computer interactionSynchronization (computer science)0202 electrical engineering electronic engineering information engineering020201 artificial intelligence & image processingCollaborative virtual realitybusiness2019 IEEE International Conference on Artificial Intelligence and Virtual Reality (AIVR)
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A collaborative virtual reality environment for liver surgery planning

2021

Abstract Surgical planning software is a key component in the treatment of tumor diseases. However, desktop-based systems provide only limited visualization and interaction opportunities. Moreover, collaborative planning among members of a surgical team is only possible to a limited extent. In this work, a collaborative virtual reality (VR) environment to assist liver surgeons in tumor surgery planning is presented. Our aim is to improve virtual resection planning between surgeons in a remote or co-located environment. The system allows surgeons to define and adjust virtual resections on patient-specific organ 3D surfaces and 2D image slices. Changes on both modalities are synchronized, whi…

Liver surgerySurgical teamModalitiesComputer sciencebusiness.industryComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISIONGeneral EngineeringComputer Graphics and Computer-Aided DesignSurgical planningVisualizationHuman-Computer InteractionSoftwareHuman–computer interactionComponent (UML)Collaborative virtual realitybusinessComputers & Graphics
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A Novel Approach for Faulty Sensor Detection and Data Correction in Wireless Sensor Network

2013

he main Wireless Sensor Networks purpose is represented by areas of interest monitoring. Even if the Wireless sensor network is properly initialized, errors can occur during its monitoring tasks. The present work describes an approach for detecting faulty sensors in Wireless Sensor Network and for correcting their corrupted data. The approach is based on the assumption that exist a spatio-temporal cross- correlations among sensors. Two sequential mathematical tools are used. The first stage is a probabilistic tools, namely Markov Random Field, for a two-fold sensor classification (working or damaged). The last stage is represented by the Locally Weighted Regression model, a learning techniq…

Locally Weighted RegressionSettore ING-INF/05 - Sistemi Di Elaborazione Delle InformazioniBrooks–Iyengar algorithmMarkov random fieldVisual sensor networkComputer scienceProbabilistic logicMarkov processMarkov Random FieldSoft sensorcomputer.software_genresymbols.namesakesymbolsMobile wireless sensor networkData miningInternet of ThingcomputerWireless sensor networkWireless Sensor Network2013 Eighth International Conference on Broadband and Wireless Computing, Communication and Applications
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The process of forming a mobile media habit: results of a longitudinal study in a real-world setting

2018

Media habits are central constructs in audience research. Yet, little is known about the formation of (media) habits. Based on theoretical elaboration and the results of a longitudinal study on the...

Longitudinal studySocial PsychologyProcess (engineering)Communicationmedia_common.quotation_subject05 social sciences050801 communication & media studies050109 social psychology0508 media and communicationsMobile mediaddc:3000501 psychology and cognitive sciencesHabitPsychologyApplied PsychologyElaborationmedia_commonCognitive psychology
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Mapping geographical inequalities in childhood diarrhoeal morbidity and mortality in low-income and middle-income countries, 2000-17: analysis for th…

2020

Background: Across low-income and middle-income countries (LMICs), one in ten deaths in children younger than 5 years is attributable to diarrhoea. The substantial between-country variation in both diarrhoea incidence and mortality is attributable to interventions that protect children, prevent infection, and treat disease. Identifying subnational regions with the highest burden and mapping associated risk factors can aid in reducing preventable childhood diarrhoea. Methods: We used Bayesian model-based geostatistics and a geolocated dataset comprising 15 072 746 children younger than 5 years from 466 surveys in 94 LMICs, in combination with findings of the Global Burden of Diseases, Injuri…

Low income countriesmedicine.medical_treatment030204 cardiovascular system & hematologyGlobal HealthTHERAPYGlobal Burden of Disease0302 clinical medicinePrevalenceGlobal healthMedicineWATER030212 general & internal medicineChildren11 Medical and Health SciencesIncidenceMortality rateIncidence (epidemiology)1. No povertyGeneral Medicine3142 Public health care science environmental and occupational healthDiarrhoea3. Good healthChild PreschoolMiddle income countriesA990 Medicine and Dentistry not elsewhere classifiedTERRITORIESLife Sciences & BiomedicineInfantsDiarrheaAFRICAmedicine.medical_specialtyChildhood deathsRJsanitationDeveloping countryChildhood diarrhoeal morbidityITC-HYBRID03 medical and health sciencesMedicine General & InternalGeneral & Internal MedicineEnvironmental healthSYSTEMATIC ANALYSISLife ScienceHumansHealthcare DisparitiesOral rehydration therapyRisk factorhand washingDeveloping CountriesDisease burdenGlobal NutritionWereldvoedingScience & TechnologySEX-SPECIFIC MORTALITYbusiness.industryCHOLERAPublic healthBayes Theoremdiarrheal diseaseLocal Burden of Disease Diarrhoea CollaboratorsITC-ISI-JOURNAL-ARTICLENAHuman medicineDiarreabusiness
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Frontline Professionals Performing Collaborative Work with Low-Income Families: Challenges across Organizational Boundaries

2020

This article discusses certain challenges relating to interagency collaboration between the Norwegian Labour and Welfare Administration (NAV) and Child Welfare Services (CWS). We have asked what obstacles to holistic work with low-income families who receive measures from NAV and CWS simultaneously can be identified. The departure point is collaboration on a local project at the municipal level. The differences between the views of the individual services (and the mandates based on these views) with regard to parental obligations have proved challenging. Using the theory of institutional logic, we have explored how different logics have influenced these services’ approaches to parenthood an…

Low incomeTrailing researchmedia_common.quotation_subjectlow-income familiesNorwegianholistic interventionTask (project management)Institutional logiclcsh:Social Sciencesinteragency collaboration050602 political science & public administration0501 psychology and cognitive sciencesSociologylcsh:Social sciences (General)media_commonparenthoodPoint (typography)business.industry05 social sciencesGeneral Medicineinstitutional logicsPublic relationslanguage.human_languageVDP::Samfunnsvitenskap: 200::Sosiologi: 2200506 political sciencelcsh:HNegotiationWork (electrical)languagelcsh:H1-99businessWelfare050104 developmental & child psychologyNordic Journal of Social Research
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Preoperative nasopharyngeal swab testing and postoperative pulmonary complications in patients undergoing elective surgery during the SARS-CoV-2 pand…

2021

Abstract Background Surgical services are preparing to scale up in areas affected by COVID-19. This study aimed to evaluate the association between preoperative SARS-CoV-2 testing and postoperative pulmonary complications in patients undergoing elective cancer surgery. Methods This international cohort study included adult patients undergoing elective surgery for cancer in areas affected by SARS-CoV-2 up to 19 April 2020. Patients suspected of SARS-CoV-2 infection before operation were excluded. The primary outcome measure was postoperative pulmonary complications at 30 days after surgery. Preoperative testing strategies were adjusted for confounding using mixed-effects models. Results Of 8…

Lung DiseasesMalexAcademicSubjects/MED00910COVID-19/diagnosisSettore MED/18 - CHIRURGIA GENERALEneoplasms030230 surgeryminorsurgical proceduresMedical and Health SciencesLung Disease0302 clinical medicinePostoperative Complications030202 anesthesiologyaged; aged 80 and over; COVID-19; elective surgical procedures; female; humans; lung diseases; male; middle aged; Nasopharynx; neoplasms; pandemics; postoperative complications; risk assessment; SARS-CoV-2; COVID-19 nucleic acid testingNeoplasmsNasopharynx80 and over030212 general & internal medicine610 Medicine & healthLungCancerlung diseasesAged 80 and overIncidence (epidemiology)ConfoundingPulmonary ComplicationLung Diseases/*etiologyNeoplasms/surgeryGeneral MedicineMiddle AgedElective Surgical Procedures/adverse effectsOncologyElective Surgical Procedures030220 oncology & carcinogenesisCOVID-19 Nucleic Acid TestingOriginal ArticleFemalePatient SafetyAcademicSubjects/MED00010Elective Surgical Procedure6.4 SurgeryHumanCohort studymedicine.medical_specialtypreoperative caresurgical proceduresCOVID-19 nucleic acid testing.elective surgical proceduresPreoperative careRisk AssessmentArticleCOVIDSurg CollaborativeNO*COVID-19 Nucleic Acid TestingVaccine Related03 medical and health sciencesClinical ResearchBiodefensemedicineNasopharynx/*virologyHumansNasopharynx/virologyElective surgeryAdverse effectPandemicsLS7_4AgedElective Surgical ProcedurePandemicbusiness.industrySARS-CoV-2Surgery Sars Cov2PreventionNo key words availableelectivesurgical proceduresLung Diseases/etiologyEvaluation of treatments and therapeutic interventionsCancerPostoperative complicationoperativenasopharynxsurgery specialtypulmonary complicationscancer surgerysars-cov-2covid-19coronavirus pandemicCOVID-19Odds ratiomedicine.diseaseConfidence intervalSurgeryCOVID-19/*diagnosisEmerging Infectious DiseasesGood Health and Well BeingNeoplasmSurgeryPostoperative Complicationpreoperative caresurgical procedures electivesurgical procedures minorsurgical procedures operativenasopharynxsurgery specialtypulmonary complicationscancer surgerysars-cov-2covid-19coronavirus pandemicElective Surgical Procedures/*adverse effectsbusiness[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
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