Search results for "LABOR"

showing 10 items of 3876 documents

Neuronal markers in the rodent pineal gland ? an immunohistochemical investigation

1990

Although some embryological and morphological features speak in favour of a neuronal character of rodent pinealocytes, histochemistry and ultrastructure let this issue appear controversial. Using antibodies to different neurofilaments, the neural adhesion molecule L1, synaptophysin and tubulin as neuronal markers, the pineal glands of rat and guinea-pig were studied by means of immunofluorescence. Neurofilament-immunoreactivity was present in some rat pineal nerve fibers and in the majority of guinea-pig pinealocytes, L1 decorated rat intrapineal nerve fibers, synaptophysin was almost ubiquitously distributed in the pineal of both species, while tubulin-immunofluorescence was seen in nerve …

Malemedicine.medical_specialtyHistologyNeurofilamentL1Cell Adhesion Molecules NeuronalGuinea PigsIntermediate FilamentsSynaptophysinNerve Tissue ProteinsPineal GlandPinealocyteGuinea pigPineal glandTubulinInternal medicinemedicineAnimalsMolecular BiologyCytoskeletonbiologyMembrane ProteinsRats Inbred StrainsCell BiologyGeneral MedicineImmunohistochemistryRatsCell biologyMedical Laboratory TechnologyEndocrinologymedicine.anatomical_structurenervous systemSynaptophysinbiology.proteinUltrastructureImmunohistochemistryAnatomyGeneral Agricultural and Biological SciencesBiomarkersHistochemistry
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The unilateral nigral lesion induces dramatic bilateral modification on rat brain monoamine neurochemistry

2009

6-Hydroxydopamine (6-OHDA) is a neurotoxic compound commonly used to induce dopamine (DA) depletion in the nigrostriatal system, mimicking Parkinson's disease (PD) in animals. The aim of the present study was to evaluate the 7-day effect of unilateral nigral lesion on rat brain monoamine neurochemistry. Five brain regions were examined: the brain stem, cerebellum, hippocampus, striatum, and cortex. 6-OHDA-unilateral lesion dramatically modified DA, serotonin (5-HT) and their metabolites contents in both sides of the different brain nuclei. Furthermore, unilateral 6-OHDA lesion reduced DA and 5-HT contents and produced a robust inversion of their turnover in the nonlesioned side compared to …

Malemedicine.medical_specialtyParkinson's diseaseChromatography High pressure liquidRats as laboratory animalsHippocampusStriatumGeneral Biochemistry Genetics and Molecular BiologyBrain stemLesionRats Sprague-Dawleychemistry.chemical_compoundbrain monoamineHistory and Philosophy of ScienceDopamineInternal medicineCerebellummedicineunilateral nigral lesionAnimalsNeurochemistryratBiogenic MonoaminesOxidopamineChromatography High Pressure Liquidbusiness.industryGeneral NeuroscienceBrainCerebral cortexRatsSubstantia NigraMonoamine neurotransmitterEndocrinologychemistrynervous systemSerotoninmedicine.symptombusinessHippocampus (Brain)NeuroscienceOxidopaminemedicine.drug
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Cell type heterogeneity of intermediate filament expression in epithelia of the human pituitary gland.

1989

In the present study we have localized immunohistochemically the intermediate filament proteins of the human pituitary gland (adenohypophysis, pars intermedia and pars tuberalis) by an indirect immunoperoxidase technique or by double immunofluorescence methods and analysed the individual cytokeratin polypeptides using two-dimensional gel electrophoresis. We found that the expression of cytokeratins in different epithelial cells of the human anterior pituitary gland was heterogeneous. Whereas the endocrine cells only expressed cytokeratins 8 and 18, the folliculo-stellate cells exhibited a reactivity for cytokeratins 7, 8, 18 and 19 as well as for GFAP and vimentin. The squamous epithelial c…

Malemedicine.medical_specialtyPituitary glandHistologyVimentinmacromolecular substancesEpitheliumDesminCytokeratinIntermediate Filament ProteinsInternal medicineGlial Fibrillary Acidic ProteinmedicineIntermediate Filament ProteinHumansVimentinIntermediate filamentMolecular BiologybiologyPars intermediaEpithelial CellsCell BiologyGeneral MedicineMolecular biologyImmunohistochemistryMedical Laboratory Technologymedicine.anatomical_structureEndocrinologyPituitary Glandbiology.proteinKeratinsFemalePars tuberalisAnatomyGeneral Agricultural and Biological SciencesEndocrine glandHistochemistry
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The old and new tests for celiac disease: which is the best test combination to diagnose celiac disease in pediatric patients?

2011

BACKGROUND In the diagnosis of celiac disease (CD), serum assays for anti-endomysium (EMA) and anti-transglutaminase (anti-tTG) antibodies have excellent diagnostic accuracy. However, these assays are less sensitive in young pediatric patients. Recently, a new ELISA test using deamidated gliadin peptides (DGP) as antigen has proved to be very sensitive and specific even in pediatric patients. In addition, anti-actin IgA antibodies (AAA) is another test that can be used in CD patients because antibody concentrations correlate with the degree of villous atrophy. This study evaluated the clinical accuracy of anti-tTG, EMA, AGA, anti-DGP and AAA and the effectiveness of these in different combi…

Malemedicine.medical_specialtySettore MED/09 - Medicina InternaTissue transglutaminaseClinical BiochemistryFluorescent Antibody TechniqueDiagnostic accuracyEnzyme-Linked Immunosorbent AssayDiseaseGastroenterologySensitivity and SpecificityAntigenInternal medicinemedicineHumansceliac disease; diagnostic test; pediatric patientspediatric patientsbiologybusiness.industryClinical Laboratory TechniquesBiochemistry (medical)InfantGeneral MedicineReference StandardsEndomysiummedicine.anatomical_structurediagnostic testCase-Control StudiesChild PreschoolElisa testbiology.proteinFemaleAntibodyGliadinbusinessceliac disease
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PROGNOSTIC VALUE OF LUNG ULTRASOUND IN OLDER NURSING HOME RESIDENTS AFFECTED BY COVID-19

2020

Objectives: Lung ultrasonographic (LUS) imaging may play an important role in the management of patients with COVID-19–associated lung injury, particularly in some special populations. However, data regarding the prognostic role of the LUS in nursing home residents, one of the populations most affected by COVID-19, are not still available. Design: Retrospective. Settings and Participants: Nursing home residents affected by COVID-19 were followed up with an LUS from April 8 to May 14, 2020, in Chioggia, Venice. Methods: COVID-19 was diagnosed through a nasopharyngeal swab. LUS results were scored using a 12-zone method. For each of the 12 zones (2 posterior, 2 anterior, 2 lateral, for both l…

Malemedicine.medical_specialtySpecial populationsCoronavirus disease 2019 (COVID-19)Lung ultrasonographyPneumonia ViralLung injuryUltrasonography lung COVID-19 nursing homeLikelihood ratios in diagnostic testingArticlelungBetacoronavirus03 medical and health sciencesCOVID-19 Testing0302 clinical medicineInternal medicinemedicineHumans030212 general & internal medicinePandemicsGeneral NursingAgedRetrospective StudiesUltrasonographyAged 80 and overClinical Laboratory TechniquesSARS-CoV-2business.industryultrasoundHealth PolicyArea under the curveCOVID-19General MedicineConfidence intervalNursing Homesnursing homeFemaleGeriatrics and GerontologyCoronavirus InfectionsbusinessNursing homes030217 neurology & neurosurgeryJournal of the American Medical Directors Association
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Visual Acuity and Contrast Sensitivity in Eyes Implanted with Aspheric and Spherical Intraocular Lenses

2009

Purpose To compare visual acuity and contrast sensitivity (CS) in eyes implanted with aspheric and spherical intraocular lenses (IOLs) after cataract surgery. Design Randomized, prospective study. Participants Five hundred twenty-four eyes from 262 cataract surgery patients implanted with 2 IOL models: the AcrySof IQ (262 eyes) and AcrySof SN60AT (262 eyes; Alcon Laboratories, Fort Worth, TX). Methods High-contrast photopic best-corrected distance visual acuity (BCVA) and CS under photopic (85 cd/m 2 ) and mesopic (6 cd/m 2 ) conditions were measured. Pupil diameter was analyzed for distance vision under both lighting conditions. Follow-up was carried out for 6 months in all patients. Main …

Malemedicine.medical_specialtyVisual acuityLightPseudophakiagenetic structuresMesopic visionmedia_common.quotation_subjectmedicine.medical_treatmentAcrylic ResinsVisual AcuityDark AdaptationIntraocular lensCataract ExtractionProsthesis DesignContrast SensitivityLens Implantation IntraocularVision MonocularOphthalmologymedicineHumansContrast (vision)Prospective StudiesAgedmedia_commonLenses Intraocularbusiness.industryPupilCataract surgeryeye diseasesOphthalmologyAlcon LaboratoriesIntraocular lensesOptometryFemalesense organsmedicine.symptombusinessPhotopic visionOphthalmology
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Refractive Lens Exchange with Foldable Toric Intraocular Lens

2009

To assess visual and refractive outcomes, and rotational stability after refractive lens exchange (RLE) with toric intraocular lens (IOL) implantation to correct ametropia and preexisting astigmatism.Prospective, nonrandomized, observational case series (self-controlled).This prospective, nonrandomized, and self-controlled study included 32 eyes of 19 consecutive patients with more than 1.00 diopter (D) of preexisting corneal astigmatism having RLE with AcrySof Toric IOL implantation (Alcon Laboratories Inc, Fort Worth, Texas, USA). Uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA), refractive sphere, and keratometric and refractive cylinder were recorded preoperatively …

Malemedicine.medical_specialtyVisual acuitygenetic structuresmedicine.medical_treatmentAcrylic ResinsVisual AcuityIntraocular lensVisual phenomenaAstigmatismRefractive lens exchangeRefraction OcularLens Implantation IntraocularSurveys and QuestionnairesOphthalmologyMyopiamedicineHumansProspective StudiesDioptreAgedLenses IntraocularPhacoemulsificationbusiness.industryAstigmatismMiddle Agedmedicine.diseaseeye diseasesOphthalmologyAlcon LaboratoriesEyeglassesPatient SatisfactionOptometryFemalesense organsmedicine.symptombusinessCorneal astigmatismAmerican Journal of Ophthalmology
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Change in kidney volume after kidney transplantation in patients with autosomal polycystic kidney disease

2018

BackgroundThe indication to bilateral nephrectomy in patients with autosomal dominant polycystic kidney scheduled for kidney transplantation is controversial. Indeed, the progressive enlargement of cysts may increase the risk of complications and the need for nephrectomy. However, very few studies investigated the change in kidney volume after kidney transplantation.Material and methodsIn this prospective cohort study, the change in native kidney volume in polycystic patients was evaluated with magnetic resonance imaging. Forty patients were included in the study. Kidney diameters and total kidney volume were evaluated with magnetic resonance imaging in patients who underwent simultaneous n…

Malemedicine.medical_treatment030232 urology & nephrology030204 cardiovascular system & hematologyKidneyPathology and Laboratory MedicineNephrectomyVascular MedicineDiagnostic Radiology0302 clinical medicineChronic Kidney DiseaseMedicine and Health SciencesRenal TransplantationPolycystic kidney diseaseMedicineProspective StudiesTomographyKidney transplantationPolycystic Kidney DiseasesKidneyMultidisciplinaryRadiology and ImagingQROrgan SizeMiddle AgedMagnetic Resonance ImagingNephrectomyTreatment Outcomemedicine.anatomical_structureNephrologyMedicineFemaleAnatomymedicine.symptomResearch Articlemedicine.medical_specialtyImaging TechniquesScienceUrologySurgical and Invasive Medical ProceduresHemorrhageNeuroimagingKidney VolumeResearch and Analysis MethodsAsymptomaticUrinary System Procedures03 medical and health sciencesSigns and SymptomsDiagnostic MedicineMedical DialysisHumansTransplantationSurgical Excisionurogenital systembusiness.industryBiology and Life SciencesKidneysRenal SystemOrgan Transplantationmedicine.diseaseKidney TransplantationComputed Axial TomographyTransplantationbusinessFollow-Up StudiesNeuroscienceBilateral NephrectomyPLOS ONE
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Langerin+ DCs regulate innate IL-17 production in the oral mucosa during Candida albicans-mediated infection

2018

The opportunistic fungal pathogen Candida albicans frequently causes diseases such as oropharyngeal candidiasis (OPC) in immunocompromised individuals. Although it is well appreciated that the cytokine IL-17 is crucial for protective immunity against OPC, the cellular source and the regulation of this cytokine during infection are still a matter of debate. Here, we directly visualized IL-17 production in the tongue of experimentally infected mice, thereby demonstrating that this key cytokine is expressed by three complementary subsets of CD90+ leukocytes: RAG-dependent αβ and γδ T cells, as well as RAG-independent ILCs. To determine the regulation of IL-17 production at the onset of OPC, we…

Malemedicine.medical_treatment2405 ParasitologyPathology and Laboratory Medicine10263 Institute of Experimental ImmunologyMonocytesMice0302 clinical medicineAnimal CellsCandida albicansBiology (General)Candida albicansMononuclear Phagocyte SystemFungal PathogensInnate Immune Systemeducation.field_of_studyEukaryotaMononuclear phagocyte systemFlow CytometryCorpus albicans3. Good healthSpectrophotometryMedical MicrobiologyCytokinesCytophotometryCellular Types10244 Institute of VirologyQH301-705.5Immune CellsImmunologyMicrobiology03 medical and health sciences1311 GeneticsGenetics1312 Molecular BiologyeducationMicrobial PathogensMolecular BiologyMouth2403 ImmunologyBlood CellsOrganismsBiology and Life SciencesDendritic CellsMolecular DevelopmentYeastMice Inbred C57BLMannose-Binding Lectins030104 developmental biologyImmunologyThy-1 Antigens570 Life sciences; biologyParasitologyImmunologic diseases. AllergyDigestive SystemDevelopmental Biology0301 basic medicineNeutrophilsPhysiologyInterleukin-1betaYeast and Fungal ModelsInterleukin-23White Blood CellsSpectrum Analysis TechniquesCandidiasis OralImmune PhysiologyLeukocytesMedicine and Health SciencesCandidaStainingbiologyInterleukin-172404 MicrobiologyCell StainingSpecific Pathogen-Free OrganismsInfectious DiseasesCytokineExperimental Organism SystemsAntigens SurfaceFemaleAnatomyPathogensResearch ArticleLangerinPopulationMycologyOpportunistic InfectionsResearch and Analysis MethodsTongueImmunityVirologymedicineAnimalsLectins C-TypeInterleukin 6Interleukin-6Mouth MucosaFungiCell BiologyRC581-607biology.organism_classificationSpecimen Preparation and TreatmentImmune Systembiology.protein2406 VirologySpleen030215 immunology
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Ischemic stroke risk during long-term follow up in patients with successful catheter ablation for atrial fibrillation in Korea

2018

The interruption of oral anticoagulation therapy (OAC) after CA of atrial fibrillation (AF) is controversial. The purpose of this study was to evaluate the relationship between successful long-term outcomes of catheter resection and SR maintenance and ischemic stroke risk in Korea. We studied 1,548 consecutive patients who were followed up for more than 2 years after CA of AF. We investigated the incidence of ischemic stroke during long-term follow-up. Compared to the AF recurrence group (n = 619), the sinus rhythm (SR) maintenance group (n = 929) had more paroxysmal AF (74.6% versus 44.4%, p<0.001), smaller LA size (39.9±5.7mm versus 42.3±6.0mm, p<0.001), and younger age (54.2±10.9 years v…

Malemedicine.medical_treatmentAnticoagulant Therapylcsh:Medicine030204 cardiovascular system & hematologyAntiplatelet TherapyPathology and Laboratory MedicineVascular MedicineBrain IschemiaGeographical LocationsElectrocardiography0302 clinical medicineRisk FactorsAtrial FibrillationMedicine and Health SciencesMedicineSinus rhythm030212 general & internal medicinelcsh:ScienceMultidisciplinaryPharmaceuticsIncidence (epidemiology)IncidenceAtrial fibrillationMiddle AgedStrokeCatheterCardiovascular TherapyBioassays and Physiological AnalysisNeurologyCardiologyCatheter AblationFemaleArrhythmiaResearch ArticleBiotechnologymedicine.medical_specialtyCathetersAsiaLong term follow upCerebrovascular DiseasesCardiologyCatheter ablationHemorrhageResearch and Analysis Methods03 medical and health sciencesSigns and SymptomsDrug TherapyDiagnostic MedicineInternal medicineRepublic of KoreaHumansIn patientIschemic StrokeKoreabusiness.industrylcsh:RElectrophysiological TechniquesBiology and Life Sciencesmedicine.diseaseIschemic strokePeople and Placeslcsh:QMedical Devices and EquipmentCardiac ElectrophysiologybusinessFollow-Up StudiesPLoS ONE
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