Search results for "LCA"

showing 10 items of 1995 documents

Ratiocalc: Software for processing data from multicomponent volcanic gas analyzers

2015

Portable gas analyzers have become a powerful tool for the real-time monitoring of volcanic gas composition over the last decade. Gas analyzers make it possible to retrieve in real-time the chemical composition of a fumarole system or a plume in an open-conduit volcano via periodic field-deployments or at permanent stations. The core of a multicomponent volcanic gas analyzer (MultiGAS) consists of spectroscopic and electrochemical sensors that are used to determine the concentrations of the most abundant volcanic gases (H2O, CO2, SO2, H2S, H2, CO and HCl) in a diluted plume and their mutual molar ratios. Processing such data is often difficult due to the high sensitivity of the sensors to e…

MineralogyInformation SystemMultiGASGas sensorsGas analyzerVolcanic GasesVolcanic gaseventGas compositionComputers in Earth SciencesGas analyzer; Gas sensors; MultiGAS; Ratiocalc; Volcanic gas; Information Systems; Computers in Earth SciencesChemical compositionevent.disaster_typegeographygeography.geographical_feature_categoryVolcanic gaProcess (computing)RatiocalcFumaroleGas analyzerPlumeVolcano13. Climate actionEnvironmental scienceGas sensorInformation SystemsComputers & Geosciences
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Scavenging of sulphur, halogens and trace metals by volcanic ash: The 2010 Eyjafjallajökull eruption

2013

The Eyjafjallajökull volcanic eruption in 2010 released considerable amounts of ash into the high troposphere-low stratosphere, leading to unprecedented disruption of air traffic over Europe. The role of such fine-grained tephra in adsorbing, and therefore rapidly scavenging, volcanogenic volatile elements such as sulphur and halogens, is explored here. We report on results (major to trace element chemistry) of leaching experiments carried out on 20 volcanic ash samples, taken from the deposits of the main phases of the eruption (March–April 2010), or directly while falling (5–9 May 2010). Ash leachate solutions from Eyjafjallajökull are dominated – among cations – by Ca and Na, and display…

Mineralogyexplosive volcanismvolcanic eruptionVolcanic GasesGeochemistry and Petrologyddc:550eventTrace metalVOLCANIC ASHmonitoring systemTephraVolatilesScavengingevent.disaster_typeVulcanian eruptionplumeChemistrystratosphere-troposphere interactionTrace elementtephrahalogentrace metalexplosive volcanism; VOLCANIC ASH; EyjafjallajökullEyjafjallajökullsulfurEnvironmental chemistryvolcanic gasVolcanic ashGeochimica et Cosmochimica Acta
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2,3,9- and 2,3,11-Trisubstituted tetrahydroprotoberberines as D2 dopaminergic ligands

2013

Dopamine-mediated neurotransmission plays an important role in relevant psychiatric and neurological disorders. Nowadays, there is an enormous interest in the development of new dopamine receptors (DR) acting drugs as potential new targets for the treatment of schizophrenia or Parkinson's disease. Previous studies have revealed that isoquinoline compounds such as tetrahydroisoquinolines (THIQs) and tetrahydroprotoberberines (THPBs) can behave as selective D-2 dopaminergic alkaloids since they share structural similarities with dopamine. In the present study we have synthesized eleven 2,3,9- and 2,3,11-trisubstituted THPB compounds (six of them are described for the first time) and evaluated…

Models MolecularBerberineStereochemistryCell SurvivalMTT and cytofluorometric analysisTheoretical calculationsMolecular Dynamics SimulationLigandsCiencias BiológicasCompostos orgànics SíntesiDrug DiscoveryAlcaloidesDopamina ReceptorsAnimalsHumansTetrahydroprotoberberinesDopamine receptorsStructure-activity relationships cytotoxicityPharmacologyMolecular StructureChemistryReceptors Dopamine D2Organic ChemistryDopaminergicGeneral MedicineBioquímica y Biología MolecularRatsDopamine receptorStructureeactivity relationships cytotoxicityQuímica orgànicaCIENCIAS NATURALES Y EXACTAS
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Modelling the enantioresolution capability of cellulose tris(3,5-dichlorophenylcarbamate) stationary phase in reversed phase conditions for neutral a…

2018

[EN] To the best of our knowledge, the prediction of the enantioresolution ability of polysaccharides-based stationary phases in liquid chromatography for structurally unrelated compounds has not been previously reported. In this study, structural information of neutral and basic compounds is used to model their enantioresolution levels obtained from an immobilised cellulose tris(3,5-dichlorophenylcarbamate) stationary phase in reversed phase conditions. Thirty-four structurally unrelated chiral drugs and pesticides, from seven families, are studied. Categorical enantioresolution levels (RsC, 0 = no baseline enantioresolution and 1 = baseline enantioresolution) are established from the expe…

Models MolecularTrisPhenylcarbamatesEnantioresolution modelling01 natural sciencesBiochemistryAnalytical Chemistrychemistry.chemical_compoundMolecular descriptorPhase (matter)Tris(35-dichlorophenylcarbamate)MoleculeLeast-Squares AnalysisPesticidesCelluloseCelluloseChromatography High Pressure LiquidReversed phase liquid chromatographyEnantioseparationsChromatography Reverse-PhasePrincipal Component AnalysisChromatography010405 organic chemistry010401 analytical chemistryOrganic ChemistryDiscriminant partial least squaresDiscriminant AnalysisStereoisomerismGeneral MedicineReversed-phase chromatography0104 chemical scienceschemistryStationary phaseAsymmetric carbonStationary phaseJournal of Chromatography A
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A novel caryophyllene type sesquiterpene lactone from Asparagus falcatus (Linn.); Structure elucidation and anti-angiogenic activity on HUVECs

2011

Abstract In this study the novel caryophyllene type sesquiterpene lactone (aspfalcolide) has been isolated from the leaves of Asparagus falcatus (Linn.) and characterized by IR, 1D NMR, 2D NMR, EI–MS, HR–ESI–MS and X-ray single crystal diffraction analysis. The aspfalcolide crystallizes in the orthorhombic space group P212121 with a = 6.37360(10), b = 7.6890(2), c = 27.3281(6) A, α = β = γ = 90° and Z = 4. One intermolecular O–H⋯O hydrogen bond enforces these natural molecules to form infinite chains through the crystal. Aspfalcolide was screened for its anti-angiogenic activity in human umbilical vein endothelial cells (HUVECs) and the result showed the remarkable inhibitory effect of aspf…

Models MolecularVascular Endothelial Growth Factor AStereochemistryMolecular ConformationAngiogenesis InhibitorsSesquiterpene lactoneUmbilical veinLactoneschemistry.chemical_compoundCell MovementDrug DiscoveryHuman Umbilical Vein Endothelial CellsHumansta116Cell ProliferationAsparagus falcatusPolycyclic SesquiterpenesPharmacologychemistry.chemical_classificationTube formationbiologyHydrogen bondCaryophylleneOrganic ChemistryGeneral Medicinebiology.organism_classificationchemistryOrthorhombic crystal systemAsparagus PlantSesquiterpenesTwo-dimensional nuclear magnetic resonance spectroscopyEuropean Journal of Medicinal Chemistry
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Variation of the BrO/SO2 molar ratio in the plume of Tungurahua volcano between 2007 and 2017 and its relationship to volcanic activity

2019

International audience; Recent long-term observations of the bromine monoxide (BrO) to sulphur dioxide (SO2) molar ratio in volcanic plumes have suggested a link between changes in the BrO/SO2 ratio and the volcanic activity. Nevertheless, understanding of the mechanisms determining this link is still limited due to the lack of studies on volcanic bromine release from the melt into the atmosphere. We present the results of 10 years (2007–2017) of observations of the BrO/SO2 molar ratio in the volcanic plume of Tungurahua volcano, Ecuador. Following the nearly continuous eruptive activity from 1999 to 2008, Tungurahua showed alternating phases of eruptive activity separated by periods of qui…

Molarratio010504 meteorology & atmospheric sciencesBromine monoxideMineralogySO2010502 geochemistry & geophysics01 natural sciencesBrOMolar ratio[SDU.STU.VO]Sciences of the Universe [physics]/Earth Sciences/Volcanologylcsh:Science0105 earth and related environmental sciencesObservational databasegeographygeography.geographical_feature_categorydegassingTungurahuaStrombolian eruptionPlumeNOVACvolcanoVolcanic plumeVolcano13. Climate actionDOASGeneral Earth and Planetary SciencesEnvironmental sciencelcsh:Q
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Enzyme-accelerated and structure-guided crystallization of calcium carbonate: Role of the carbonic anhydrase in the homologous system

2014

Abstract The calcareous spicules from sponges, e.g. from Sycon raphanus, are composed of almost pure calcium carbonate. In order to elucidate the formation of those structural skeletal elements, the function of the enzyme carbonic anhydrase (CA), isolated from this species, during the in vitro calcium carbonate-based spicule formation, was investigated. It is shown that the recombinant sponge CA substantially accelerates calcium carbonate formation in the in vitro diffusion assay. A stoichiometric calculation revealed that the turnover rate of the sponge CA during the calcification process amounts to 25 CO2 s−1 × molecule CA−1. During this enzymatically driven process, initially pat-like pa…

Molecular Sequence DataInorganic chemistryBiomedical Engineeringchemistry.chemical_elementCalciumBiochemistryCalcium Carbonatelaw.inventionBiomaterialschemistry.chemical_compoundSponge spiculelawSpectroscopy Fourier Transform InfraredAnimalsAmino Acid SequenceSycon raphanusCrystallizationMolecular BiologyCarbonic AnhydrasesMineralsbiologyGeneral MedicineElementsbiology.organism_classificationPoriferaCrystallographySpongeCalcium carbonatechemistryCrystallizationCalcareousBiotechnologyBiomineralizationActa Biomaterialia
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A NANOPARTICULATE DRUG-DELIVERY SYSTEM FOR RIVASTIGMINE: PHYSICO-CHEMICAL AND IN VITRO BIOLOGICAL CHARACTERIZATION

2007

The preparation and characterization of surface-PE Gylated polymeric nanoparticles are described. These systems were obtained by UV irradiation of PHM and PHM-PEG(2000) as an inverse microemulsion, using an aqueous solution of the PHM/PHM-PEG(2000) copolymer mixture as the internal phase and triacetin saturated with water as the external phase, and characterized by dimensional analysis, zeta-potential measurements and XPS. in vitro biological tests demonstrated their cell compatibility and their ability to escape from phagocytosis. Rivastigmine was encapsulated into the nanoparticle structure and drug-release profiles from loaded samples were investigated in PBS at pH = 7.4 and human plasma.

Molecular StructureCell SurvivalUltraviolet RaysPhenylcarbamatesRivastigmineHemolysisPolyethylene GlycolsPOLYMERIC NANOPARTICLES RIVASTIGMINE DRUG DELIVERYDrug Delivery SystemsPolymethacrylic AcidsSettore CHIM/09 - Farmaceutico Tecnologico ApplicativoCell Line TumorDelayed-Action PreparationsHumansNanoparticlesPeptidesTriacetin
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Demonstracion historico-chronologica de un engaño, o inconsideracion, que padeciò, y trasladò a la prensa ... Fr. Marcos de Alcala ... sobre, y en…

1737

Port. amb orla tip. i cites literàries orlades al verso Caplletres ornades, fris, banda Sign.: œ-œœœ4, A-P4, Q2 Postil·les marginals Reclams

Monasterio de las Descalzas Reales (Madrid) Obres anteriors a 1800Alcalá Marcos de (O.F.M.) Crítica i interpretació Obres anteriors a 1800
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Speciation of vanadium in urban, industrial and volcanic soils by a modified Tessier method

2016

Vanadium (V) concentrations in industrial, urban and volcanic soils were sequentially extracted using a modified Tessier's method. The voltammetric technique was used to determine V concentrations in solutions obtained from the various extraction steps. At the reference stations, the V concentrations (sum of four individual fractions) in soils ranged from 0.72 to 0.24 g kg(-1) dry weight (d.w.) with a mean value of 0.18 g kg(-1) d.w. V concentrations in soils of the Palermo urban area ranged from 0.34 to 2.1 g kg(-1) d.w., in the Milazzo (industrial) area between 0.26 and 5.4 g kg(-1) d.w. and in the volcanic area near Mt. Etna from 0.91 to 2.9 g kg(-1) d.w. When the V concentrations around…

Monitoringmedia_common.quotation_subject0211 other engineering and technologiesVanadiumchemistry.chemical_elementVolcanic Eruptions02 engineering and technologyChemical Fractionation010501 environmental sciencesManagement Monitoring Policy and Law01 natural sciencesManagement Monitoring Policy and Law.Dry weightIndustrySoil PollutantsEnvironmental ChemistryCities0105 earth and related environmental sciencesmedia_common021110 strategic defence & security studiesgeographygeography.geographical_feature_categoryPolicy and LawMean valueChemical fractionationExtraction (chemistry)Environmental and Occupational HealthPublic Health Environmental and Occupational HealthVanadiumElectrochemical TechniquesGeneral MedicineManagementSpeciationItalychemistryVolcanoEnvironmental chemistryPolicy and Law.Soil waterEnvironmental sciencePublic HealthEnvironmental Monitoring
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