Search results for "LF"
showing 10 items of 12543 documents
El 31 congreso federal del PSOE. Madrid, 22-24 enero 1988
2014
El 31 congreso federal del PSOE. Madrid, 22-24 enero 1988. Previo al Vº Congreso del PSPV-PSOE, se celebraba en Madrid el 31 Congreso Federal del PSOE, del 22 al 24 enero 1988. El peso orgánico del PSPV·PSOE en el congreso federal del PSOE se concretaba en ser la segunda federación en afiliación, tras Andalucía, con 29.804 militantes, y 119 delegados, un 13,8% de los 860 delegados electos. PSPV·PSOE: Estos son sus poderes: 29.804 militantes. 119 delegados al congreso federal del partido, que equivalían, casi, al 15% del total de delegados. 453 organizaciones locales, repartidas entre las tres provincias, y 36 ejecutivas comarcales. Militantes suyos presiden la Generalidad, las Cortes Valenc…
Vidējā pirmsskolas vecuma bērnu pašapkalpošanās prasmju pilnveide lomu rotaļās
2019
Bakalaura darba temats – Vidējā pirmsskolas vecumā bērnu pašapkalpošanās prasmes pilnveide lomu rotaļās. Darba autore – Aļina Artjuka Darba zinātniskais vadītājs – prof. Dr.paed. Maruta Sīle Pētījuma objekts – Lomu rotaļa Pētījuma priekšmets – vidējā pirmsskolas vecumā bērnu pašapkalpošanas prasmes Pētījuma mērķis – pētīt četrgadīgu bērnu pašapkalpošanas prasmes pilnveides iespējas lomu rotaļās Pētījuma hipotēze - četrgadīgu bērnu pašapkalpošanas prasmes pilnveide lomu rotaļās būs sekmīgāka, ja •bērnu interesēs lomu rotaļu saturs un tematika; •tiks vaicāts un cienīts bērnu viedoklis; •ģimenē un pirmsskolas izglītības iestādē būs vienādas prasības Pētījuma uzdevumi: 1.Analizēt pedagoģijas un…
Statistikas jēdzienu apguves novērtēšana Latvijas Universitātē
2022
Bakalaura darba tēma ir “Statistikas jēdzienu apguves novērtēšana Latvijas Universitātē”, kas veltīta mērisntrumenta (testa) izstrādei un adaptācijai latviešu valodā, lai sekmīgi novērtētu studentu statistikas jēdzienu apguvi. Testa izstrāde un tulkošana ir balstīta uz Oklahamas Universitātē jau izstrādāto un vairāku gadu veikto (2002-2005) statistikas koncepta izvērtēšanu, un tā izstrādāto testu. Darbā tiek aprakstīti soļi, kas nepieciešami statistiskā instrumenta (testa) adaptācijai un darba praktiskajā daļā tiek analizēti pirmie iegūtie tulkotā statistisko jēdzienu apguves novērtēšanas testa rezultāti un salīdzināts testā kopējo pareizo iegūto punktu skaits ar studentu Latvijas Universit…
Produzione di vini bianchi senza l’uso di solfiti
2014
Measurement of dielectron production in central Pb-Pb collisions at √sNN = 2.76 TeV
2019
Published by the American Physical Society under the terms of the Creative Commons Attribution 4.0 International license. Further distribution of this work must maintain attribution to the author(s) and the published article's title, journal citation, and DOI. The first measurement of dielectron (e + e −) production in central (0 – 10 %) Pb – Pb collisions at √sNN=2.76TeV at the LHC is presented. The dielectron invariant-mass spectrum is compared to the expected contributions from hadron decays in the invariant-mass range 0 < mee < 3.5 GeV / c2. The ratio of data and the cocktail of hadronic contributions without vacuum ρ0 is measured in the invariant-mass range 0.15 < mee < 0.7 GeV / c2, w…
Pathogenic mechanisms of how human parvovirus breaks self-tolerance
2017
It is known that viral infections can cause acute, chronic, and autoimmune diseases (ADs). However, the mechanism of how a persistent viral infection contributes to ADs remains still unclear. In this thesis, pathological and immunological aspects of how common viruses can initiate autoimmunity were investigated, and human parvovirus B19 (B19V) was employed as a model virus. B19V non-structural protein 1 (NS1), a superfamily 3 (SF3) helicase, initiated DNA damage resulting in cellular apoptosis. The apoptotic bodies (ApoBods) induced by B19V NS1 were purified and characterized. These ApoBods contained viral NS1 proteins with modified autoimmune-associated self-antigens, e.g. DNA, Smith, Apol…
DNA-induced structural changes in the papillomavirus capsid.
2001
ABSTRACT Human papillomavirus capsid assembly requires intercapsomeric disulfide bonds between molecules of the major capsid protein L1. Virions isolated from naturally occurring lesions have a higher degree of cross-linking than virus-like particles (VLPs), which have been generated in eukaryotic expression systems. Here we show that DNA encapsidation into VLPs leads to increased cross-linking between L1 molecules comparable to that seen in virions. A higher trypsin resistance, indicating a tighter association of capsomeres through DNA interaction, accompanies this structural change.
Papillomavirus assembly requires trimerization of the major capsid protein by disulfides between two highly conserved cysteines.
1998
ABSTRACT We have used viruslike particles (VLPs) of human papillomaviruses to study the structure and assembly of the viral capsid. We demonstrate that mutation of either of two highly conserved cysteines of the major capsid protein L1 to serine completely prevents the assembly of VLPs but not of capsomers, whereas mutation of all other cysteines leaves VLP assembly unaffected. These two cysteines form intercapsomeric disulfides yielding an L1 trimer. Trimerization comprises about half of the L1 molecules in VLPs but all L1 molecules in complete virions. We suggest that trimerization of L1 is indispensable for the stabilization of intercapsomeric contacts in papillomavirus capsids.
Glie et neurones : vers un partenariat actif influençant le comportement sensoriel chez la drosophile
2014
Turystyczny przewodnik po Piekle Mikołaja Reja, czyli o międzyplanetarnych podróżach duszy ludzkiej
2020
The article deals with the complex issue of presenting the underworld in the Reja's Wizerunk. The author draws attention to the presence in the output of the old Polish poet of many visionary elements borrowed from the most varied traditions and religious systems. The popular pattern of searching for spiritual perfection, fixed in the archetype of the topographic movement of the hero (Latin: Homo viator) turns out to be particularly visible. It turns out that at the very foundations of this imaginative pattern there is an ancient doctrine or interplanetary wandering of the soul. Most of the work was focused on the description of XI songs of Reja’s WizerunV, where a description of hell appea…