Search results for "LIES"

Production of polymeric micro- and nanostructures with tunable properties as pharmaceutical delivery systems

2020

Abstract The production of novel graft copolymers based on poly-e-caprolactone (PCL) and polyaspartamide are useful to realize structures for potential biomedical applications. Here, the synthesis of pegylated PCL/polyhydroxyethyl aspartamide (PHEA) graft copolymers (PHEA-g-SUCC-PCL-g-PEG) with tunable composition, was achieved by followpling a synthetic strategy that involved first the grafting of preformed PCL on PHEA backbone, then polyethylen glycol (PEG), by using 1,1′-carbonyldiimidazole (CDI) to speed up the condensation reaction. Graft copolymers with a Derivatization Degree (DD) in PCL ranging between 1.1 and 4.4 mol% were obtained, and processable with different technologies for t…

Clinical evaluation of neodymium-iron-boron (Ne2Fe14B) rare earth magnets in the treatment of mid line diastemas

2015

Background: To evaluate the closure of midline diastema using the Neodymium-Iron-Boron magnets and to compare the treatment duration of midline diastemas with the use of magnets compared to regular orthodontic treatment. Materials and Methods: Thirty patients with age group 12 to 30 years with the midline diastema ranging from 0.5 to 3mm were selected. These patients were divided into two groups. Diastema closure in one group was accomplished by conventional method, in other group was done with Ne 2 Fe 14 B magnets. These magnets were fitted to the labial surfaces of the maxillary central incisors such a way that the opposite poles of the magnets face each other. At each appointment, study …

2020

We sought to determine the effects of the use of a Bioengineered Combo Dual-Therapy CD34 Antibody-Covered Sirolimus-Eluting Coronary Stent (Combo® DTS) in patients with chronic total occlusion (CTO) by evaluating clinical outcomes and by performing an optical coherence tomography (OCT) analysis. We retrospectively analyzed data from 39 patients who had successfully undergone OCT-guided revascularization of a CTO being treated with a Combo® DTS. Clinical assessment, angiography (with quantitative coronary angiography analysis) and OCT examination were performed at baseline and at follow-up. The median follow-up period was 189 days, ranging from 157 to 615 days. At follow-up, revascularizatio…

Unilateral multicystic dysplastic kidney in infants exposed to antiepileptic drugs during pregnancy

2007

Prenatal exposure to antiepileptic drugs (AEDs) increases the risk of major congenital malformations (MCM) in the fetus. AED-related abnormalities include heart and neural tube defects, cleft palate, and urogenital abnormalities. Among the various congenital anomalies of the kidney and urinary tract (CAKUT), multicystic dysplastic kidney (MCDK) disease is one of the most severe expressions. Although prenatal ultrasound (US) examination has increased the prenatal diagnosis of MCDK, the pathogenesis is still unclear. We report on four cases of MCDK in infants of epileptic women treated with AEDs during pregnancy. From October 2003 to June 2006, we observed four infants with unilateral MCDK bo…

Il Nero d’Avola “sui lieviti” per migliorare i caratteri sensoriali

2008

New Physics adventures in the LHC age

2017

La física de partículas está viviendo actualmente una era de exploración que comenzó con la observación en el LHC del bosón de Higgs, proporcionando así al Modelo Estándar de la Física de Partículas la elusiva pieza final que lo completa. Si bien esta teoría es extremadamente exitosa, se acepta comúnmente que no es la teoría final ya que no puede responder a todas las preguntas teóricas ni a ciertas observaciones experimentales. Por lo tanto, se espera que Nueva Física que extienda al Modelo Estándar aparezca pronto, aunque esto bien podría ser sólo una esperanza. Esta tesis recoge algunas de las aventuras en la búsqueda de Nueva Física. Se organiza en tres partes: la Parte I introduce, en …

Genetic and Environmental Controls on Nitrous Oxide Accumulation in Lakes

2015

We studied potential links between environmental factors, nitrous oxide (N2O) accumulation, and genetic indicators of nitrite and N2O reducing bacteria in 12 boreal lakes. Denitrifying bacteria were investigated by quantifying genes encoding nitrite and N2O reductases (nirS/nirK and nosZ, respectively, including the two phylogenetically distinct clades nosZ(I) and nosZ(II)) in lake sediments. Summertime N2O accumulation and hypolimnetic nitrate concentrations were positively correlated both at the inter-lake scale and within a depth transect of an individual lake (Lake Vanajavesi). The variability in the individual nirS, nirK, nosZ(I), and nosZ(II) gene abundances was high (up to tenfold) a…

Contrast-Enhanced Magnetic Resonance Angiography of the Pulmonary Vasculature

1998

Magnetic resonance angiography (MRA) has been established as a powerful noninvasive imaging modality. Its applications to the study of the pulmonary vasculature have been hampered by a multitude of factors, such as respiratory and cardiac motion artifacts, saturation problems, long acquisition times

Genome Evolution in the Primary Endosymbiont of Whiteflies Sheds Light on Their Divergence

2015

International audience; Hemipteran insects are well-known in their ability to establish symbiotic relationships with bacteria. Among them, heteropteran insects present an array of symbiotic systems, ranging from the most common gut crypt symbiosis to the more restricted bacteriome-associated endosymbiosis, which have only been detected in members of the superfamily Lygaeoidea and the family Cimicidae so far. Genomic data of heteropteran endosymbionts are scarce and have merely been analyzed from the Wolbachia endosymbiont in bed bug and a few gut crypt-associated symbionts in pentatomoid bugs. In this study, we present the first detailed genomic analysis of a bacteriome-associated endosymbi…

Family involvement in the intensive care unit in four Nordic countries

2021

BackgroundRelevance to clinical practice The findings from the study highlighting family involvement, high-quality communication and flexible visiting policy as central aspects of family care may inspire clinicians to identify aspects of everyday family care in their ICUs calling for further improvement.Aims and objectivesTo describe family involvement, communication practices and visiting policies in adult ICUs.DesignA cross-sectional survey.MethodA questionnaire consisting of 11 sections was developed, pilot tested and e-mailed to 196 ICUs. The participants were intensive care nurses in adult ICUs in four Nordic countries.ResultsThe survey was conducted in October to December 2019. The re…