Search results for "LIPIDS"
showing 10 items of 2228 documents
The effect of high-intensity interval exercise program on blood lipids and hormones in recreationally active adults
2015
Johdanto. Tyypin 2 diabetes sekä verenkieroelimistön sairaudet ovat yleistyneet ja niiden tehokkaimpana ehkäisynä pidetään liikuntaa. Suomessa ihmiset eivät noudata liikuntasuosi-tuksia ja syyksi inaktiivisuuteen sanotaankin olevan ajan ja motivaation puute. Korkeate-hoinen intervalliharjoittelu on ollut suosittua siksi, että se säästää aikaa ja sen vaikutuksien terveyteen ja kuntoon ajatellaan olevan vähintäänkin samanlaiset kun aerobisen harjoittelun. Tämän tutkimuksen tarkoituksena oli tutkia onko kahden erityyppisen intervalliharjoittelun (juoksu ja kuntopiiri) välillä eroja veren lipideissä ja hormoneissa, kun työmäärä ja intensiteetti pysyvät samana. Tällä hetkellä tutkimuksia tästä a…
Efecto del polimorfismo de la apolipoproteína E en el perfil lipoproteico y riesgo cardiovascular en una población mediterránea
2002
Fundamento La asociacion de las variantes comunes del gen de la apolipoproteina E (apo E)con arteriosclerosis varia segun las poblaciones. Nuestro objetivo fue estimar la asociacion entreestas variantes geneticas (alelos e2, e3 y e4) con las concentraciones de lipidos plasmaticosy el riesgo de enfermedad cardiovascular (ECV) en una poblacion mediterranea espanola. Pacientes y metodo Se ha realizado un estudio transversal en 486 individuos (144 varones y342 mujeres) procedentes de poblacion general mediterranea (7-85 anos). Se determino el genotipode la apo E y variables antropometricas, bioquimicas y del estilo de vida. Resultados La frecuencia alelica para e2 y e4 fue baja (0,052; interval…
Prenatal exposure to cannabinoids evokes long-lasting functional alterations by targeting CB 1 receptors on developing cortical neurons
2015
The CB1 cannabinoid receptor, the main target of Δ(9)-tetrahydrocannabinol (THC), the most prominent psychoactive compound of marijuana, plays a crucial regulatory role in brain development as evidenced by the neurodevelopmental consequences of its manipulation in animal models. Likewise, recreational cannabis use during pregnancy affects brain structure and function of the progeny. However, the precise neurobiological substrates underlying the consequences of prenatal THC exposure remain unknown. As CB1 signaling is known to modulate long-range corticofugal connectivity, we analyzed the impact of THC exposure on cortical projection neuron development. THC administration to pregnant mice in…
N-glycosylation efficiency is determined by the distance to the C-terminus and the amino acid preceding an Asn-Ser-Thr sequon
2011
N-glycosylation is the most common and versatile protein modification. In eukaryotic cells, this modification is catalyzed cotranslationally by the enzyme oligosaccharyltransferase, which targets the β-amide of the asparagine in an Asn-Xaa-Ser/Thr consensus sequon (where Xaa is any amino acid but proline) in nascent proteins as they enter the endoplasmic reticulum. Because modification of the glycosylation acceptor site on membrane proteins occurs in a compartment-specific manner, the presence of glycosylation is used to indicate membrane protein topology. Moreover, glycosylation sites can be added to gain topological information. In this study, we explored the determinants of N-glycosylati…
Possible Roles of Mannoproteins in the Construction of Candida Albicans Cell Wall
1993
The shape of Candida albicans cells depends on their cell walls and some of their mannoproteins may act as modulators of the final molecular architecture. If that were the case, the wall mannoproteins might form part of what could be called a “morphogenetic code”.
A review of the biological and pharmacological activities of saponins.
1996
Summary This paper reviews the important biological and pharmacological activities of saponins reported over the last few years. These include cancer-related activity, as well as antiphlogistic and antiallergic, immunomodulating, antihepatotoxic, antiviral, hypoglycemic, antifungal and molluscicidal activities. The action of saponins on the cardiovascular, central nervous, and endocrine systems and other miscellaneous effects are also discussed.
Synthetic Inhibitors of Cell Adhesion: A Glycopeptide from E-Selectin Ligand 1 (ESL-1) with the Arabino Sialyl Lewisx Structure
2001
Particularly selective methods are required for the synthesis of arabino sialyl Lewisx glycopeptides owing to the acid-labile β-arabinopyranoside bond. It is important for the inhibition of cell adhesion that the arabino sialyl Lewisx glycopeptide 1, which contains the Gly 672 -Asp 681 sequence of the E-selectin Ligand 1 (ESL-1), binds ten times more strongly than sialyl Lewisx to E-selectin, although it is monovalent and does not contain L-fucose, which is considered essential.
Chemosignals ‘designed for’ neonates in mammals
2014
Focused Meeting of the Animal Behaviour Society and the Biochemical Society; absent
An attachment-independent biochemical timer of the spindle assembly checkpoint. Qian et al.
2017
Original data of cell images and western blots of the manuscript "An attachment-independent biochemical timer of the spindle assembly checkpoint." by Qian et al.
Enzyme und Biokatalyse
1996
Enzyme (Fermente) sind biologische Katalysatoren. Die Substanz (Metabolit), deren chemische Umsetzung sie katalysieren, nennt man Substrat.