Search results for "LOCI"
showing 10 items of 1277 documents
In HCV-related liver cirrhosis, local pulse wave velocity increases and in decompensated patients correlates with poorer survival
2018
BackgroundCirrhotic cardiomyopathy (CCM) refers to cardiac dysfunction in patients with liver cirrhosis, in the absence of other known cardiac disease.MethodsControl group and patients diagnosed of liver cirrhosis without known cardiac disease or hepatocellular carcinoma were enrolled for this clinical observation study. Patients with diabetes mellitus, hypertension were excluded. Absolute global longitudinal strain, one-point carotid pulse wave velocity (one-point PWV) and various parameters were measured in resting status.ResultsThere were 29 participants in the control group and 80 patients in the liver cirrhosis group. 27.8% of cirrhotic patients presented with normal systolic but abnor…
Hemodynamic changes in splanchnic circulation after orthotopic liver transplantation in patients with liver cirrhosis
2002
Background: Liver cirrhosis increases portal vein pressure and alters the splanchnic circulation. With Doppler sonography, we investigated the hemodynamic changes in the portal vein, superior mesenteric artery, hepatic and splenic arteries and spleen size in a group of patients with end-stage liver disease before and after orthotopic liver transplantation (OLT). Methods: Ten patients (seven male, three female; mean age = 48.8 ± 7.6 years) who underwent OLT for liver cirrhosis mainly associated with hepatitis C virus infection completed the study. The control group consisted of 10 patients matched by sex and age who had no gastroenterologic or vascular diseases. All patients underwent duplex…
Genome-wide meta-analyses identify three loci associated with primary biliary cirrhosis.
2010
A genome-wide association screen for primary biliary cirrhosis risk alleles was performed in an Italian cohort. The results from the Italian cohort replicated IL12A and IL12RB associations, and a combined meta-analysis using a Canadian dataset identified newly associated loci at SPIB (P = 7.9 × 10−11, odds ratio (OR) = 1.46), IRF5-TNPO3 (P = 2.8 × 10−10, OR = 1.63) and 17q12-21 (P = 1.7 × 10−10, OR = 1.38).
Method to find the Minimum 1D Linear Gradient Model for Seismic Tomography
2016
The changes in the state of a geophysical medium before a strong earthquake can be found by studying of 3D seismic velocity images constructed for consecutive time windows. A preliminary step is to see changes with time in a minimum 1D model. In this paper we develop a method that finds the parameters of the minimum linear gradient model by applying a two-dimensional Taylor series of the observed data for the seismic ray and by performing least-square minimization for all seismic rays. This allows us to obtain the mean value of the discrete observed variable, close to zero value.
ADV measurements of velocity distributions in a gravel-bed flume
2003
Velocity measurements carried out by an acoustic doppler velocimeter (ADV) in a rectangular laboratory flume having a gravel bed are presented. The velocity profiles are measured in six verticals of the channel cross-section having an increasing distance (from 4 to 38.5 cm) from the flume wall. The experimental runs are carried out for five different bed arrangements, characterized by different concentrations of coarser elements, and for the two conditions of small- and large-scale roughness. For both hydraulic conditions, the velocity measurements are first used to test the applicability of the Dean profile and of the logarithmic profile corrected by a divergence function proposed in this …
Characterization of a medium size Xe/TMA TPC instrumented with microbulk Micromegas, using low-energy gamma-rays
2014
NEXT-MM is a general-purpose high pressure (10 bar, $\sim25$ l active volume) Xenon-based TPC, read out in charge mode with an 8 cm $\times$8 cm-segmented 700 cm$^2$ plane (1152 ch) of the latest microbulk-Micromegas technology. It has been recently commissioned at University of Zaragoza as part of the R&D of the NEXT $0\nu\beta\beta$ experiment, although the experiment's first stage is currently being built based on a SiPM/PMT-readout concept relying on electroluminescence. Around 2 million events were collected during the last months, stemming from the low energy $\gamma$-rays emitted by a $^{241}$Am source when interacting with the Xenon gas ($\epsilon$ = 26, 30, 59.5 keV). The localized…
Instability of relativistic sheared jets and distinction between FRI and FRII sources
2002
We investigate the shear-driven instability of nonmagnetic relativistic jets with the bulk velocity, V , dependent on the cylindric radius, r. It is shown that instability can arise for any dependence of the velocity (or the Lorentz factor that is the same) on r. The shear-driven instability can e ectively operate in the whole volume of a jet. The growth time can be shorter than that of the Kelvin-Helmholtz instability. The considered instability leads to a turbulization of jets and can account for a distiction between the jets in the FRI and FRII sources. Urpin, V., Vadim.Urpin@uv.es
A DERIVATION OF THE VLASOV-NAVIER-STOKES MODEL FOR AEROSOL FLOWS FROM KINETIC THEORY
2016
This article proposes a derivation of the Vlasov-Navier-Stokes system for spray/aerosol flows. The distribution function of the dispersed phase is governed by a Vlasov-equation, while the velocity field of the propellant satisfies the Navier-Stokes equations for incompressible fluids. The dynamics of the dispersed phase and of the propellant are coupled through the drag force exerted by the propellant on the dispersed phase. We present a formal derivation of this model from a multiphase Boltzmann system for a binary gaseous mixture, involving the droplets/dust particles in the dispersed phase as one species, and the gas molecules as the other species. Under suitable assumptions on the colli…
Comparison of two techniques (in vivo and ex-vivo) for evaluating the elastic properties of the ascending aorta: Prospective cohort study.
2021
Introduction Aneurysms of the ascending aorta (AA) correspond to a dilatation of the ascending aorta that progressively evolves over several years. The main complication of aneurysms of the ascending aorta is type A aortic dissection, which is associated with very high rates of morbidity and mortality. Prophylactic ascending aorta replacement guidelines are currently based on maximal AA diameter. However, this criterion is imperfect. Stretching tests on the aorta carried out ex-vivo make it possible to determine the elastic properties of healthy and aneurysmal aortic fragments (tension test, resistance before rupture). For several years now, cardiac magnetic resonance imaging (MRI) has pro…
Guided flows in coronal magnetic flux tubes
2018
There is evidence for coronal plasma flows to break down into fragments and to be laminar. We investigate this effect by modeling flows confined along magnetic channels. We consider a full MHD model of a solar atmosphere box with a dipole magnetic field. We compare the propagation of a cylindrical flow perfectly aligned to the field to that of another one with a slight misalignment. We assume a flow speed of 200 km/s, and an ambient magnetic field of 30 G. We find that while the aligned flow maintains its cylindrical symmetry while it travels along the magnetic tube, the misaligned one is rapidly squashed on one side, becoming laminar and eventually fragmented because of the interaction and…