Search results for "LONG"

showing 10 items of 3969 documents

Supratransmission-induced traveling breathers in long Josephson junctions

2022

The emergence of travelling sine-Gordon breathers due to the nonlinear supratransmission effect is theoretically studied in a long Josephson junction driven by suitable magnetic pulses, taking into account the presence of dissipation, a current bias, and a thermal noise source. The simulations clearly indicate that, depending on the pulse's shape and the values of the main system parameters, such a configuration can effectively yield breather excitations only. Furthermore, a nonmonotonic behavior of the breather-only generation probability is observed as a function of the noise intensity. Finally, the dynamics of the supratransmission-induced breathers is characterized by looking at quantit…

Numerical AnalysisSettore FIS/02 - Fisica Teorica Modelli E Metodi MatematiciStatistical Mechanics (cond-mat.stat-mech)Condensed Matter - Mesoscale and Nanoscale PhysicsLong Josephson junctions; Traveling sine-Gordon breathers; Nonlinear supratransmission; Stochastic fluctuationsApplied MathematicsFOS: Physical sciencesStochastic fluctuationsNonlinear supratransmissionLong Josephson junctionsTraveling sine-Gordon breathersModeling and SimulationMesoscale and Nanoscale Physics (cond-mat.mes-hall)Nonlinear Sciences::Pattern Formation and SolitonsCondensed Matter - Statistical MechanicsCommunications in Nonlinear Science and Numerical Simulation
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Impact of long chain fatty acids on sweet taste sensitivity in mice. Role of the GPR120/GLP-1 signaling

2011

Nutrition and DieteticsBiochemistryGPR120Sweet tasteSensitivity (control systems)BiologyLong chainGeneral PsychologyAppetite
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Economic impact of mepolizumab in uncontrolled severe eosinophilic asthma, in real life

2021

Abstract Background and aims Severe asthma is burdened by frequent exacerbations and use of oral corticosteroids (OCS) which worsen patients’ health and increase healthcare spending. Aim of this study was to assess the clinical and economic effect of adding mepolizumab (MEP) for the treatment of these patients. Methods Patients >18 years old, referred to 8 asthma clinics, starting MEP between May 2017 and December 2018, were enrolled and followed-up for 12 months. Information in the 12 months before mepolizumab were collected retrospectively. The evaluation parameters included: OCS use, number of exacerbations/hospitalizations, concomitant therapies, comorbidity, and annual number of workin…

OR Odds RatioPediatricsSevere asthmaExacerbationAnti IL-5; Comorbidities; Mepolizumab; OCS; Pharmacoeconomics; Severe asthmagastroesophageal reflux diseaseSettore MED/10 - MALATTIE DELL'APPARATO RESPIRATORIOICS inhaled corticosteroidRate ratioOCS Oral Corticosteroidslaw.inventionComorbiditiesLAMA long acting muscarinic antagonist0302 clinical medicineRandomized controlled trialfractional nitric oxideInterquartile rangelawlong acting beta 2 agonistOdds RatioImmunology and AllergyRR Rate Ratio030223 otorhinolaryngologyPharmacoeconomicLOS Length of stayLOSIQRLAMAMEP MepolizumabORCISD Standard DeviationMEPPharmacoeconomicsACT Asthma Control TestComorbiditieCI Confidence Intervalsmedicine.druglcsh:Immunologic diseases. AllergyPulmonary and Respiratory Medicinemedicine.medical_specialtyinterquartile rangelong acting muscarinic antagonistImmunologyLABALABA long acting beta 2 agonistComorbidities Mepolizumab OCS Pharmacoeconomics Severe asthma Anti IL-5RRArticleRate Ratiochronic obstructive pulmonary disease03 medical and health sciencesPharmacoeconomicsOCS Oral CorticosteroidAsthma Control TestConfidence IntervalsFeNO fractional nitric oxideRCTs Randomized Controlled TrialmedicineCOPDGERD gastroesophageal reflux diseaseFeNOIQR interquartile rangeMepolizumabSDAsthmaRCTsOral Corticosteroidsbusiness.industryGERDmedicine.diseaseICS inhaled corticosteroidsACTComorbidityRandomized Controlled TrialsCI Confidence IntervalRCTs Randomized Controlled TrialsOCSCOPD chronic obstructive pulmonary disease030228 respiratory systemICSStandard DeviationLength of stayAnti IL-5inhaled corticosteroidslcsh:RC581-607businessMepolizumab
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Association Between Long-Term Job Strain and Metabolic Syndrome Factor Across Sex and Occupation

2006

The present study investigated whether long-term job strain increases the prevalence of risk for metabolic syndrome, a cluster of risk factors for cardiovascular diseases, across sex and occupation. The participants (64 men, 62 women) were drawn from the Jyväskylä Longitudinal Study of Personality and Social Development, Finland. Job strain was measured by a combination of high job demands and low job control ( Karasek, 1979 ) at ages 36 and 42. Metabolic syndrome was measured at age 42. The results indicated that both sex and occupational group moderated the association between long-term job strain and the metabolic syndrome factor but in an unexpected way. In women, low long-term job str…

Occupational groupLongitudinal studyJob strainJob controlmedia_common.quotation_subject05 social sciencesmedicine.diseaseDisease clusterDevelopmental psychology03 medical and health sciences0302 clinical medicine0502 economics and businessmedicinePersonality030212 general & internal medicineMetabolic syndromePsychologyAssociation (psychology)050203 business & managementBiological PsychiatryGeneral Psychologymedia_commonDemographyJournal of Individual Differences
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Life-Space Mobility in Parkinson's Disease: Associations with Motor and Non-Motor Symptoms.

2019

Background To describe life-space mobility and explore associations of motor and non-motor symptoms with life-space mobility in people with Parkinson’s disease (PD). Methods About 164 community-dwelling persons with PD (mean age 71.6 years, 64.6% men) received a postal survey and a subsequent home visit. Motor assessments included perceived walking difficulties (Walk-12G), mobility (Timed Up and Go test), motor symptoms (UPDRS-III), and freezing of gait (item 3, FOG-Qsa). Non-motor symptoms included depressive symptoms (GDS-15), pain, fatigue (NHP-EN), and global cognition (MoCA). Life-space mobility was assessed with the life-space assessment (LSA). Calculations included composite score (r…

Occupational therapyMaleAgingmedicine.medical_specialtyNeurologyParkinson's diseaseParkinsonin tautiDiseaseTimed Up and Go testelämänlaatuMotor Activity03 medical and health sciences0302 clinical medicineliikuntakykyparticipationMedicineassistive devicesHumans030212 general & internal medicineLongitudinal StudiesMobility LimitationFatigueosallistuminenAgedAged 80 and overbusiness.industryConfoundingCognitionParkinson Diseaseta3142apuvälineetMiddle Agedmedicine.diseaseGaitmobilityliikkuvuusPhysical therapyLinear ModelsFemaleIndependent LivingGeriatrics and Gerontologybusinesshuman activities030217 neurology & neurosurgerywalking difficultiesThe journals of gerontology. Series A, Biological sciences and medical sciences
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Physiological advantages of dwarfing in surviving extinctions in high-CO2 oceans

2015

Excessive CO2 in the present-day ocean-atmosphere system is causing ocean acidification, and is likely to cause a severe biodiversity decline in the future, mirroring effects in many past mass extinctions. Fossil records demonstrate that organisms surviving such events were often smaller than those before, a phenomenon called the Lilliput effect. Here, we show that two gastropod species adapted to acidified seawater at shallow-water CO2 seeps were smaller than those found in normal pH conditions and had higher mass-specific energy consumption but significantly lower whole-animal metabolic energy demand. These physiological changes allowed the animals to maintain calcification and to partial…

Ocean Acidification International Coordination Centre (OA-ICC)IdentificationSalinityTemperateBicarbonate ion standard deviationBottles or small containers/Aquaria (<20 L)Alkalinity total standard deviationinorganicAlkalinityExperimentTemperature waterCarbon inorganic dissolvedWidthCalculated using seacarb after Nisumaa et al 2010Aragonite saturation stateRespiration rate oxygenAlkalinity totalBottles or small containers Aquaria 20 LtotalCO2 ventpHRespirationCalcification rate of calcium carbonateTemperatureMonthdissolvedCarbonate ionLaboratory experimentPartial pressure of carbon dioxide (water) at sea surface temperature (wet air)Temperature water standard deviationRespiration rateEarth System ResearchField observationstandard deviationThicknessCalcification/DissolutionPotentiometric titrationCalcite saturation statePotentiometricwaterPartial pressure of carbon dioxideSiteGrowth MorphologyFigureAragonite saturation state standard deviationBenthosMediterranean SeaOcean Acidification International Coordination Centre OA ICCCalcite saturation state standard deviationAnimaliaBicarbonate ionLONGITUDECalculated using seacarb after Nisumaa et al. (2010)SpeciesCyclope neriteaBottles or small containers/Aquaria (&lt;20 L)Calculated using CO2SYSHeightPartial pressure of carbon dioxide standard deviationCarbonate system computation flagpH standard deviationCarbonate ion standard deviationFugacity of carbon dioxide (water) at sea surface temperature (wet air)CarbonHeight/width ratioTreatmentPartial pressure of carbon dioxide water at sea surface temperature wet airCarbon dioxideMolluscaGrowth/MorphologySingle speciesCalcification DissolutionLATITUDEHeight width ratioBenthic animalsFugacity of carbon dioxide water at sea surface temperature wet airCoast and continental shelfNassarius corniculusoxygenTable
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Could the acid-base status of Antarctic sea urchins indicate a better-than-expected resilience to near-future ocean acidification?

2015

Increasing atmospheric carbon dioxide concentration alters the chemistry of the oceans towards more acidic conditions. Polar oceans are particularly affected due to their low temperature, low carbonate content and mixing patterns, for instance upwellings. Calcifying organisms are expected to be highly impacted by the decrease in the oceans' pH and carbonate ions concentration. In particular, sea urchins, members of the phylum Echinodermata, are hypothesized to be at risk due to their high-magnesium calcite skeleton. However, tolerance to ocean acidification in metazoans is first linked to acid-base regulation capacities of the extracellular fluids. No information on this is available to dat…

Ocean Acidification International Coordination Centre (OA-ICC)SalinityNotocidaris gaussensisBicarbonate ion standard deviationinorganicAlkalinity total standard deviationAlkalinityCoulometric titrationExperimentCarbon inorganic dissolvedTemperature waterSizeCoelomic fluidCalculated using seacarb after Nisumaa et al 2010CalculatedAragonite saturation stateCtenocidaris giganteaAlkalinity totaltotalAmphipneustes loriolipHTemperaturedissolvedAcid base regulationCarbonate ionPartial pressure of carbon dioxide (water) at sea surface temperature (wet air)Carbon dioxide standard deviationSterechinus neumayeriEarth System ResearchAporocidaris eltanianaδ13Cstandard deviationField observationPolarStation labelEchinodermataPotentiometric titrationCalcite saturation stateCoelomic fluid alkalinityPotentiometricwaterPartial pressure of carbon dioxideAmphipneustes similisAragonite saturation state standard deviationBenthosDATE TIMEOcean Acidification International Coordination Centre OA ICCSterechinus antarcticusAnimaliaCalcite saturation state standard deviationBicarbonate ionLONGITUDECalculated using seacarb after Nisumaa et al. (2010)SpeciesCalculated using CO2SYScarbonEvent labelPartial pressure of carbon dioxide standard deviationCoelomic fluid carbon inorganic dissolvedCarbonate system computation flagAcid-base regulationpH standard deviationCarbonate ion standard deviationFugacity of carbon dioxide (water) at sea surface temperature (wet air)Amphipneustes rostratusPartial pressure of carbon dioxide water at sea surface temperature wet airDATE/TIMECarbon dioxideDifferenceSingle speciesCoelomic fluid pHLATITUDEFugacity of carbon dioxide water at sea surface temperature wet airAntarcticBenthic animalsCoast and continental shelfAbatus cavernosus
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Ocean acidification impairs vermetid reef recruitment

2014

Vermetids form reefs in sub-tropical and warm-temperate waters that protect coasts from erosion, regulate sediment transport and accumulation, serve as carbon sinks and provide habitat for other species. The gastropods that form these reefs brood encapsulated larvae; they are threatened by rapid environmental changes since their ability to disperse is very limited. We used transplant experiments along a natural CO2 gradient to assess ocean acidification effects on the reef-building gastropod Dendropoma petraeum. We found that although D. petraeum were able to reproduce and brood at elevated levels of CO2, recruitment success was adversely affected. Long-term exposure to acidified conditions…

Ocean Acidification International Coordination Centre (OA-ICC)SalinityTemperateSurvivalAbundance per areainorganicAlkalinityIncubation durationExperimentTemperature waterCarbon inorganic dissolvedNeogoniolithon brassica-floridaCalculated using seacarb after Nisumaa et al 2010Aragonite saturation stateAlkalinity totalSalinity standard errortotalCO2 ventMortality SurvivalpHReproductionTemperaturePartial pressure of carbon dioxide (water) at sea surface temperature (wet air) standard errorStrontium/Calcium ratiodissolvedMagnesium/Calcium ratioCarbonate ionPartial pressure of carbon dioxide (water) at sea surface temperature (wet air)Field experimentstandard errorEarth System ResearchRecruitmentMortality/SurvivalFOS: Medical biotechnologygeographic locationsPotentiometric titrationCalcite saturation stateCoveragePotentiometricwaterSiteGrowth MorphologyFigureAlkalinity total standard errorBenthosReplicateMediterranean SeaOcean Acidification International Coordination Centre OA ICCAnimaliaBicarbonate ionNeogoniolithon brassica floridaLONGITUDETemperature water standard errorCalculated using seacarb after Nisumaa et al. (2010)SpeciespH standard errorCalculated using CO2SYSfungiCarbonate system computation flagFugacity of carbon dioxide (water) at sea surface temperature (wet air)CarbonAragonite saturation state standard errorPartial pressure of carbon dioxide water at sea surface temperature wet airCarbon dioxideMolluscaGrowth/MorphologySingle speciesLATITUDEBenthic animalsFugacity of carbon dioxide water at sea surface temperature wet airMagnesium Calcium ratioCoast and continental shelfDendropoma petraeumStrontium Calcium ratio
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Seaweed fails to prevent ocean acidification impact on foraminifera along a shallow-water CO2 gradient

2015

Ocean acidification causes biodiversity loss, alters ecosystems, and may impact food security, as shells of small organisms dissolve easily in corrosive waters. There is a suggestion that photosynthetic organisms could mitigate ocean acidification on a local scale, through seagrass protection or seaweed cultivation, as net ecosystem organic production raises the saturation state of calcium carbonate making seawater less corrosive. Here, we used a natural gradient in calcium carbonate saturation, caused by shallow-water CO2 seeps in the Mediterranean Sea, to assess whether seaweed that is resistant to acidification (Padina pavonica) could prevent adverse effects of acidification on epiphytic…

Ocean Acidification International Coordination Centre (OA-ICC)TemperateIdentificationSalinityCommunity composition and diversityTriloculinella dilatatainorganicAlkalinityElphidium spMiliolinella sp.Miliolinella subrotundaQuinqueloculina sp.Daitrona spTemperature waterCarbon inorganic dissolvedCalculated using seacarb after Nisumaa et al 2010Adelosina longirostraPercentageAragonite saturation stateMiliolinella spRosalina globularisAlkalinity totaltotalElphidium sp.Elphidium crispumCO2 ventElphidium advenumpHTemperaturedissolvedPseudotriloculina spCarbonate ionPartial pressure of carbon dioxide (water) at sea surface temperature (wet air)Rosalina spQuinqueloculina annectensEarth System ResearchHaynesina depressulaField observationElphidium margaritaceumPotentiometric titrationCalcite saturation statePotentiometricwaterMassilina gualtierianaRocky-shore communitySpiroloculina ornataQuinqueloculina auberianaBenthosDaitrona sp.Pileolina patelliformisOcean Acidification International Coordination Centre OA ICCMediterranean SeaBicarbonate ionCalculated using seacarb after Nisumaa et al. (2010)SpeciesVertebralina striataAffinetrina gualtierianaElphidium macellumCalculated using CO2SYSIndividualsCarbonate system computation flagFugacity of carbon dioxide (water) at sea surface temperature (wet air)Rosalina sp.CarbonBiomass/Abundance/Elemental compositionBolivina pseudoplicataPartial pressure of carbon dioxide water at sea surface temperature wet airCarbon dioxideQuinqueloculina stelligeraQuinqueloculina spPeneroplis pertususRocky shore communityEntire communityPeneroplis planatusFugacity of carbon dioxide water at sea surface temperature wet airCornuspira involvensBiomass Abundance Elemental compositionCoast and continental shelfLobatula lobatulaQuinqueloculina boscianaPseudotriloculina sp.
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Shallow water marine sediment bacterial community shifts along a natural CO2 gradient in the Mediterranean Sea Off vulcano, Italy

2014

The effects of increasing atmospheric CO(2) on ocean ecosystems are a major environmental concern, as rapid shoaling of the carbonate saturation horizon is exposing vast areas of marine sediments to corrosive waters worldwide. Natural CO(2) gradients off Vulcano, Italy, have revealed profound ecosystem changes along rocky shore habitats as carbonate saturation levels decrease, but no investigations have yet been made of the sedimentary habitat. Here, we sampled the upper 2 cm of volcanic sand in three zones, ambient (median pCO(2) 419 µatm, minimum Omega (arag) 3.77), moderately CO(2)-enriched (median pCO(2) 592 µatm, minimum Omega (arag) 2.96), and highly CO(2)-enriched (median pCO(2) 1611…

Ocean Acidification International Coordination Centre (OA-ICC)TemperateSalinityPotentiometric titrationCalcite saturation stateCommunity composition and diversityPotentiometricinorganicwaterAlkalinitySiteFigureBenthosTemperature waterCarbon inorganic dissolvedAbundanceCalculated using seacarb after Nisumaa et al 2010Ocean Acidification International Coordination Centre OA ICCMediterranean SeaBicarbonate ionAragonite saturation stateSoft-bottom communityAlkalinity totalLONGITUDEtotalCalculated using seacarb after Nisumaa et al. (2010)CO2 ventSpeciesShannon Diversity IndexpHCalculated using CO2SYSTemperatureCarbonate system computation flagdissolvedFugacity of carbon dioxide (water) at sea surface temperature (wet air)Carbonate ionCarbonPartial pressure of carbon dioxide (water) at sea surface temperature (wet air)Partial pressure of carbon dioxide water at sea surface temperature wet airCarbon dioxideSoft bottom communityEntire communityEarth System ResearchLATITUDEFugacity of carbon dioxide water at sea surface temperature wet airGroupCoast and continental shelfField observationClass
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