Search results for "LPI"

H7, a protein kinase C inhibitor, increases the glutathione content of neuroblastoma cells

1992

AbstractIt is shown that the intracellular glutathione (GSH) concentration of neuroblastoma-2a cells in culture increases with a maximum at 24 h after starting treatment with 1-(5-isoquinolinylsulfonyl)-2-methylpiperazine (H7), an inhibitor of protein kinase C (PKC). Other inhibitors of this and other protein kinases, e.g. sphingosine, staurosporine, and HA 1004, at the concentrations tested, had a less marked or negligible effect on intracellular GSH concentration. 12-O-Tetradecanoylphorbol-13-acetate (TPA) was also tested and showed no significant effect 24 h after addition.

Distribution, floristic structure and habitat requirements of the riparian forest community Populetum talassicae ass. nova in the Central Pamir-Alai …

2013

This paper discusses the floristic structure, distribution and habitat requirements of a new forest syntaxon, <em>Populetum talassicae </em>ass. nova. The potential range of the <em>Populetum talassicae </em>association comprises the central Pamir-Alai and Tian-Shan Mountains in Middle Asia. The biotope of this community comprises high mountain river valleys and shore zones of mountain lakes situ- ated at elevations between 2200 and 2750 m. Phytocoenoses of the <em>Populetum talassicae </em>association are characterized by a clear predominance in the tree layer of a characteristic species of the association ‒ <em>Populus talassica</em>. Shrubs…

How to resist subduction: evidence for large-scale out-of-sequence thrusting during Eocene collision in western Turkey

2001

Significant along-strike variations have locked large parts of the Alpine subduction complex in the Eastern Mediterranean in the Eocene, and defined the end of high-pressure accretion in western Turkey. Structural analysis reveals that the Anatolide belt in western Turkey formed under greenschist facies metamorphic conditions in the Eocene when a high-pressure metamorphic fragment of the Adriatic plate (the Cycladic blueschist unit) was thrust onto the imbricated mid-crustal units of the Anatolian microcontinent (the Menderes nappes). The contact between the Cycladic blueschist unit and the Menderes nappes, the Cyclades–Menderes thrust, represents an out-of-sequence ramp which cuts up-sect…

Horizontal contraction or horizontal extension? Heterogeneous Late Eocene and early Oligocene general shearing during blueschist and greenschist faci…

1995

Mylonitic structures related to two orogenic events are described from the upper and lower contacts of the Combin zone and the immediately overlying upper Austroalpine Dent Blanche nappe/Mont Mary klippe and the directly underlying lower Austroalpine Etirol-Levaz slice. The first event, Late Eocene in age, commenced during blueschist facies P-T conditions, but pre-dated the peak of subsequent greenschist facies overprint. The second event, Early Oligocene in age, took place during retrograde greenschist facies conditions. Most sense of shear indicators associated with the retrograde mylonites indicate top SE shearing, but subordinate top NW displacing shear sense indicators have also been m…

A case of arrhythmogenic right ventricular cardiomyopathy without ventricular arrhythmias

2014

Abstract We submit a case report of a 21-year-old man admitted to our emergency room for acute right heart failure. Arrhythmogenic right ventricular cardiomyopathy (ARVC) was diagnosed but ventricular arrhythmias have never been detected. On the basis of the diagnosis of ARVC and for the frequent episodes of symptomatic bradycardia, the patient underwent implantation of a biventricular defibrillator (CRT-D). In ARVC symptoms usually appear between the ages of 30–50. Especially in young patients the most common clinical presentation of ARVC are palpitations and syncope due to ventricular tachycardia with left bundle branch morphology. In cases of older patients in whom the disease has been d…

Bridging the gap between research and practice : using phenomenographic findings to develop training for career practitioners

2021

AbstractThis study contends that phenomenography offers both a useful research method and practical tools for developing education and training for career practitioners. After introducing the basic principles of phenomenography, the study reviews previous research on its potential in developing pedagogical practices. It explores how the phenomenographic findings were utilized to design an online skills training programme for career practitioners. The study finds that phenomenographic research serves three practical pedagogical purposes: (1) revealing how learners understand certain concepts or phenomena, (2) elucidating how these understandings differ; and (3) identifying critical aspects i…

A method of data structuring for the study of diffusion processes of raw materials and manufactured objects

2017

International audience; Workgroup 3 of the ArchaeDyn II programme aims at studying the diffusion systems of products in ancient times. In order to be able to structure data in GIS in an appropriate way, we propose to go through three levels of modelling: the first one aims at gathering together the different components of the diffusion systems taking into account their interactions; the second corresponds to a conceptual data model created with the help of the HBDS method, that will, as we get to the third stage, lead to the creation of a "three-dimensional" geodatabase. Here we point out the fact that the approach through the simple notion of “site” is not sufficient to study the products’…

Professional educators and burnout

2004

In recent years the risk of developing a burnout syndrome among workers in the helping professions has been clearly stated. Although burnout syndrome, in fact, is threatening different professional activities, incidence was reported higher in sanitary and social professions. In this work the risk of developing a Burnout syndrome was evidenced to occur in Educators working in the socio-sanitary area. Causal relationships where indicated not only in the working context and in the peculiar characteristic of the patients, but also in the precarious, from the juridical point of view, working conditions.

Aligot d'estepa, Ratonero de las estepas (VER0000134)

Altres noms vulgars: Common Buzzard (Western Steppe) (Anglès), Buse variable (vulpinus) (Francès), Mäusebussard-vulpinus (Alemany) Gabinet de Vertebrats (Departament de Zoologia), Facultat de Ciències Biològiques (Campus de Burjassot), C/ Doctor Moliner, s/n, Bloque B. 5é plant, Burjassot (Valencia). Armari: 1-2

Atlas Lingüístico de la Península Ibérica (ALPI): Estudi i edició del País Valencià

2001

La tesi doctoral “Atlas Lingüístico de la Península Ibérica (ALPI): Estudi i edició del País Valencià” pretén recuperar un material lingüístic (fonètic, morfosintàctic i lèxic) inèdit recollit al País Valencià entre 1934 (pobles castellanoparlants) i 1935 (pobles valencianoparlants) per investigadors de la talla de M. Sanchis Guarner i F. de B. Moll. La recuperació d’aquest material està feta de forma digital, escrita (edició de les enquestes) i il·lustrada per mapes lingüístics (cartografia selectiva). Es tracta d’unes enquestes lingüístiques projectades pel Centre d’Estudis Històrics de Madrid (precedent de l’actual CSIC), presidit per R. Menéndez Pidal, qui va encarregar el projecte al m…