Search results for "LTE"
showing 10 items of 4531 documents
The triterpenoid ursolic acid ameliorates stress in Caenorhabditis elegans by affecting the depression-associated genes skn-1 and prdx2.
2021
Abstract Introduction Depression is one of the leading causes of death worldwide. Lower antioxidant concentrations and increased oxidative stress levels contribute to the development of depression. Effective and tolerable medications are urgently needed. Nrf2 and PRDX2 are promising targets in the treatment of oxidative stress and, therefore, promising for the development of novel antidepressants. Ursolic acid (UA), a natural triterpenoid found in various plants is known to exert neuroprotective and antioxidant effects. Skn-1 (which corresponds to human Nrf2) and prdx2 deficient mutants of the nematode Caenorhabditis elegans are suitable models to study the effect of UA on these targets. Ad…
Flavonoids from Erythrina schliebenii
2017
Prenylated and O-methylflavonoids including one new pterocarpan (1), three new isoflavones (2–4), and nineteen known natural products (5–23) were isolated and identified from the root, stem bark, and leaf extracts of Erythrina schliebenii. The crude extracts and their constituents were evaluated for antitubercular activity against Mycobacterium tuberculosis (H37Rv strain), showing MICs of 32–64 μg mL–1 and 36.9–101.8 μM, respectively. Evaluation of their toxicity against the aggressive human breast cancer cell line MDA-MB-231 indicated EC50 values of 13.0–290.6 μM (pure compounds) and 38.3 to >100 μg mL–1 (crude extracts).
Journal Club
2013
Antonio Belguardo. Un maestro nella Palermo tra XV e XVI secolo: il regesto documentario
2016
Le informazioni documentarie emerse in questi ultimi anni sulla figura di Antonio Belguardo permettono di tracciare con maggiore compiutezza il profilo biografico e la parabola professionale di uno dei più prolifici protagonisti della stagione tardogotica dell’architettura siciliana; la sua attività, per quanto sinora noto, si concentra prevalentemente a Palermo tra l’ultimo quarto del XV secolo e i primi decenni del XVI. New documents that have come to light on Antonio Belguardo allow us to draw a more complete biographic profile of one of the most prolific protagonists of Late Gothic Sicilian architecture; His activity, as far as we know, was mainly carried out in Palermo, between the las…
Editoriale
2019
Il numero che proponiamo ha per titolo “Antropologia del viaggio e del prendersi cura dell’Altro” e propone cinque articoli che da diversi punti di os- servazione si occupano del rapporto con l’alterità. Viene indagata la relazione con l’altro che arriva nel nostro territorio attraverso viaggi al limite della sopravvivenza, che fugge da miserie, guerre e maltratta- menti.
A Tool for Predicting the Dynamic Response of Biotrickling Filters for VOC Removal
2016
This article presents the development of a MATLAB® computer program to simulate the performance of biotrickling filters. Since these filters behave differently during spraying and nonspraying cycles, the presented simulation tool is built on top of a mathematical description of each situation. The resulting variable-structure model is then used as the basis for simulation experiments. The model presented herein represents the first attempt to take into account the variable spraying pattern usually found in industrial installations. Overall, the software is flexible and easy to use, allowing the user to specify the emission concentration pattern, the gas concentration pattern, as well as the…
We are Still Learning from Death: After CPR, Balloon Expanding Valve (Intuity Aortic Valve) Revealed to be in Position
2021
Patients with high predicated risk undergo TAVI as an alternative treatment to surgical valve replacement...
Vascular Activity of (-)-Anonaine, (-)-Roemerine and (-)-Pukateine, Three Natural 6a(R)-1,2-Methylenedioxyaporphines with Different Affinities for α1…
2004
We have studied the mechanism of action of three 6a( R)-1,2-methylenedioxyaporphines as vasorelaxant compounds. The alkaloids assayed showed different affinities for the three human cloned alpha (1)-adrenoceptor (AR) subtypes stably expressed in rat-1 fibroblasts, showing lower affinity for alpha(1B)-AR with regard to the alpha(1A)- or alpha(1D)-subtypes. These three natural compounds are more potent inhibitors of [ (3)H]-prazosin binding than of [ (3)H]-diltiazem binding to rat cerebral cortical membranes. As all these alkaloids inhibited noradrenaline (NA)-induced [ (3)H]-inositol phosphate formation in cerebral cortex and rat tail artery, they may be safely viewed as alpha (1)-AR antagon…
Sturmian words and overexponential codimension growth
2018
Abstract Let A be a non necessarily associative algebra over a field of characteristic zero satisfying a non-trivial polynomial identity. If A is a finite dimensional algebra or an associative algebra, it is known that the sequence c n ( A ) , n = 1 , 2 , … , of codimensions of A is exponentially bounded. If A is an infinite dimensional non associative algebra such sequence can have overexponential growth. Such phenomenon is present also in the case of Lie or Jordan algebras. In all known examples the smallest overexponential growth of c n ( A ) is ( n ! ) 1 2 . Here we construct a family of algebras whose codimension sequence grows like ( n ! ) α , for any real number α with 0 α 1 .