Search results for "Lag"

showing 10 items of 3124 documents

Collagen copolymer posterior chamber phakic intraocular lens supported by the ciliary sulcus to treat myopia: One-year follow-up

2014

Purpose To evaluate the predictability, stability, safety, and efficacy of Visian V4b Implantable Collamer Lens phakic intraocular lens (pIOL) implantation to treat varying degrees of myopia. Setting Fernandez-Vega Ophthalmological Institute, Oviedo, Spain. Design Prospective nonrandomized clinical study. Methods The uncorrected (UDVA) and corrected (CDVA) distance visual acuities, refraction, pIOL vault, and adverse effects were evaluated 12 months postoperatively. Results The study enrolled 121 eyes (68 patients). The mean spherical equivalent decreased from −8.61 diopters (D) ± 3.41 (SD) (range −18.75 to −2.25 D) preoperatively to −0.18 ± 0.29 D (range −1.25 to 0.50 D) 12 months postoper…

AdultMalePhakic Intraocular Lensesmedicine.medical_specialtyCiliary sulcusgenetic structuresOne year follow upPolymersVisual AcuityBiocompatible MaterialsPhakic intraocular lensYoung AdultLens Implantation IntraocularOphthalmologyMyopiamedicineHumansProspective StudiesIntraoperative ComplicationsProspective cohort studyDioptreImplantable collamer lensEfficacy indexbusiness.industryCiliary Bodyeye diseasesSensory SystemsPosterior chamber phakic intraocular lensOphthalmologyFemaleSurgeryCollagenbusinessJournal of Cataract and Refractive Surgery
researchProduct

Metabolic Evaluation of 94 Patients 5 to 16 Years After Ileocecal Pouch (Mainz Pouch 1) Continent Urinary Diversion

2003

PURPOSE In continent urinary diversion metabolic disturbances may be encountered in long-term followup. We evaluated metabolic consequences in patients with a minimum followup of 5 years after Mainz pouch 1 urinary diversion.At our institution continent urinary diversion using the ileocecal segment was performed between 1983 and 1995 in 458 patients. A total of 94 patients with an ileocecal pouch for a minimum of 5 years were reevaluated for metabolic changes. Median followup was 9.0 years. Routine laboratory parameters, blood gas analysis, vitamin B12, vitamin D25, cross-laps, bone specific alkaline phosphatase, osteocalcin and propeptide of type I collagen were obtained. Bone density was …

AdultMalePhosphopeptidesmedicine.medical_specialtyBone diseaseBone densityUrologymedicine.medical_treatmentUrinary systemOsteocalcinOsteoporosisSodium CitratePostoperative ComplicationsCalcitriolBone DensityReference ValuesPotassium CitrateHumansMedicineCitratesMegaloblastic anemiaAgedbusiness.industryUrinary Reservoirs ContinentUrinary diversionMiddle AgedAlkaline Phosphatasemedicine.diseaseSurgeryVitamin B 12FemaleCollagenBlood Gas AnalysisPouchAcidosisEnergy MetabolismbusinessContinent Urinary DiversionProcollagenFollow-Up StudiesJournal of Urology
researchProduct

Reaction time and electromyographic activity during a sprint start.

1990

Eight male sprinters were filmed running three maximal starts over 3 m on a long force platform. The subjects were divided into two groups (n = 4) according to the leg on which the electromyograph (EMG) electrodes were fixed. When in the set position one group had electrodes on the front leg (FLG) and the other group on the rear leg (RLG). The EMG activities of the gastrocnemius caput laterale muscle (GA), vastus lateralis muscle (VL), biceps femoris caput longum muscle (BF), rectus femoris muscle (RF) and gluteus maximus muscle (GM) were recorded telemetrically using surface electrodes. Total reaction time (TRT) was defined as the time from the gun signal until a horizontal force was produ…

AdultMalePhysiologyVastus lateralis musclePostureElectromyographyRectus femoris muscleFilaggrin ProteinsBicepsRunningPhysiology (medical)medicineReaction TimeHumansOrthopedics and Sports MedicineForce platformGluteus maximus muscleLegPhysical Education and Trainingmedicine.diagnostic_testChemistryElectromyographyMusclesPublic Health Environmental and Occupational HealthBody movementGeneral MedicineAnatomySprintEuropean journal of applied physiology and occupational physiology
researchProduct

Extracellular matrix composition in COPD

2012

Extracellular matrix (ECM) composition has an important role in determining airway structure. We postulated that ECM lung composition of chronic obstructive pulmonary disease (COPD) patients differs from that observed in smoking and nonsmoking subjects without airflow obstruction. We determined the fractional areas of elastic fibres, type-I, -III and -IV collagen, versican, decorin, biglycan, lumican, fibronectin and tenascin in different compartments of the large and small airways and lung parenchyma in 26 COPD patients, 26 smokers without COPD and 16 nonsmoking control subjects. The fractional area of elastic fibres was higher in non-obstructed smokers than in COPD and nonsmoking controls…

AdultMalePulmonary and Respiratory MedicineLumicanPathologymedicine.medical_specialtyDecorinLumicanTenascinSettore MED/10 - Malattie Dell'Apparato RespiratorioPulmonary Disease Chronic ObstructiveBiglycanParenchymamedicineHumansCOPDLungAgedCOPDLungbiologybusiness.industryBiglycanSmokingTenascinMiddle Agedrespiratory systemmedicine.diseaseImmunohistochemistryExtracellular MatrixFibronectinsRespiratory Function Testsrespiratory tract diseasesmedicine.anatomical_structureChondroitin Sulfate ProteoglycansKeratan SulfateCase-Control Studiesbiology.proteinVersicanFemaleCollagenDecorinbusiness
researchProduct

Haematopoietic stem cell transplantation for vasculitis including Behçet's disease and polychondritis: a retrospective analysis of patients recorded …

2006

Objective: To evaluate the feasibility of haematopoietic stem cell transplantation (HSCT) in vasculitis. Methods: This is a retrospective analysis of patients who had received HSCT for vasculitic diseases and have been reported to the European League Against Rheumatism autoimmune disease or European Bone Marrow Transplantation ProMISe databases. Information about the disease and outcome was obtained by a questionnaire sent to the referring centres. Response of the disease to HSCT was defined as partial or complete responses according to the ability to reduce immunosuppression after HSCT. In addition, the Medline database was searched for reports on HSCT in patients with vasculitis. Results:…

AdultMaleReoperationVasculitisDatabases Factualmedicine.medical_treatmentMEDLINEImmunologyBehcet's diseasecomputer.software_genreTransplantation AutologousGeneral Biochemistry Genetics and Molecular BiologyRheumatologyimmune system diseasesRecurrencehemic and lymphatic diseasesmedicineImmunology and AllergyHumansTransplantation HomologousRetrospective StudiesImmunosuppression TherapyDatabasePolyarteritis nodosabusiness.industryBehcet SyndromeHematopoietic Stem Cell TransplantationRetrospective cohort studyImmunosuppressionmedicine.diseaseConnective tissue diseaseTransplantationExtended ReportEuropesurgical procedures operativeTreatment OutcomeFemalebusinessVasculitiscomputerCartilage DiseasesRheumatism
researchProduct

[Myringoplasties. A retrospective analysis of our surgical outcomes].

2010

Objective: The aim of this study was to present myringoplasty case results in our department. Different factors were studied to confirm their prognostic value. Materials and methods: A total of 126 myringoplasties from 2006 until 2010 were reviewed, collecting patient-related details, descriptions of the anatomical defect and the most interesting surgical aspects. Results: Subtotal perforations (35.7%) were the most frequently observed. In 89.7% of the operations, the transcanal approach was preferred. The medial technique (underlay) to the tympanic membrane was the most performed (97.6%). Cartilage was the principal graft used (82.5%). Complete closure of the perforation was obtained in 71…

AdultMaleReoperationmedicine.medical_specialtyAdolescentPerforation (oil well)MyringoplastyYoung AdultEar CartilageAudiometryMyringoplastyMiddle ear mucosaRetrospective analysisMedicineHumansChildAgedRetrospective StudiesTympanic Membrane Perforationbusiness.industryCartilageGeneral MedicineRecovery of FunctionMiddle AgedSurgerymedicine.anatomical_structureTreatment OutcomeChild PreschoolFemalebusinessFollow-Up StudiesActa otorrinolaringologica espanola
researchProduct

Long-term bony integration and resorption kinetics of a xenogeneic bone substitute after sinus floor augmentation: histomorphometric analyses of huma…

2013

In this case series, a systematic histomorphometric analysis of two human bone biopsy specimens was conducted 1 and 5 years after grafting with a xenogeneic bovine bone substitute material (BSM). While the 1-year specimen still showed extensive signs of an active desmal ossification, the specimen after 5 years mainly showed mature lamellar bone without bone turnover or remodeling. A completed bony integration without extensive resorption of the BSM particles could be detected. Altogether, a good integration in the bone with osteoconduction and a high biocompatibility was seen.

AdultMaleSinus Floor AugmentationBone RegenerationBone substituteBiopsyHuman boneDentistryBone MatrixSinus Floor AugmentationOsteocytesBone remodelingImaging Three-DimensionalOsseointegrationOsteogenesisBiopsymedicineMaxillaAnimalsHumansLongitudinal StudiesBone ResorptionMineralsBone Transplantationmedicine.diagnostic_testOssificationbusiness.industryDental Implantation EndosseousMembranes ArtificialX-Ray MicrotomographyMiddle AgedResorptionBovine boneBone SubstitutesPeriodonticsHeterograftsCattleFemaleCollagenOral Surgerymedicine.symptombusinessFollow-Up Studies
researchProduct

Ultrastructural study by backscattered electron imaging and elemental microanalysis of biomaterial-to-bone interface and mineral degradation of bovin…

2012

Objectives The aim of this study was to perform an ultrastructural study of the bone-to-biomaterial interface and biomaterial mineral degradation in retrieved bone biopsies following maxillary sinus augmentation using bovine xenografts (Endobon®) in 15 clinical cases. Materials and methods Nine months after sinus lifting, bone cores were harvested from the maxillary sinus. The specimens were processed for observation under a scanning electron microscope with backscattered electron imaging (SEM-BSE). In addition, chemical analysis and elemental mapping of the mineral composition were generated using a microanalytical system based on energy-dispersive X-ray spectrometry (EDX). Results No clin…

AdultMaleSinus Floor AugmentationMaxillary sinusScanning electron microscopeSurface PropertiesBiopsyDentistrySinus Floor AugmentationMicroanalysisSurgical FlapsmedicineAnimalsHumansSinus (anatomy)Chemistrybusiness.industryJaw Edentulous PartiallyDental Implantation EndosseousBiomaterialSpectrometry X-Ray EmissionMaxillary SinusMiddle AgedResorptionmedicine.anatomical_structureTreatment OutcomeElemental analysisMicroscopy Electron ScanningHeterograftsCattleFemaleCollagenOral SurgerybusinessBiomedical engineeringClinical oral implants research
researchProduct

T2 Mapping of the Sacroiliac Joints in Patients with Axial Spondyloarthritis

2020

Purpose: To test whether T2 mapping of the sacro-iliac joints (SIJs) might help identifying patients with spondyloarthritis. Method: This study included 20 biologic-naive patients with axial spondyloarthritis (10 females; mean age: 38 ± 9years; range, 19–47) and 27 controls (16 males; mean age = 39 ± 13years; range = 28–71) who prospectively underwent SIJs MRI at 1.5 T, including a multislice multiecho spin-echo sequence. Standard MRIs were reviewed to assess the SIJs according to the Assessment of SpondyloArthritis International Society (ASAS) criteria and SPondyloArthritis Research Consortium of Canada (SPARCC) MRI index. T2 maps obtained from multiecho sequences were used to draw regions…

AdultMaleT2 mappingSacroiliac joint030218 nuclear medicine & medical imagingYoung Adult03 medical and health sciences0302 clinical medicineMagnetic resonance imagingSpondylarthritisChi-square testHumansMedicineRadiology Nuclear Medicine and imagingIn patientMultisliceProspective StudiesSacroiliitisAxial spondyloarthritisBASDAISacroiliitis.Observer Variationbusiness.industrySacroiliitisCurve analysisReproducibility of ResultsGeneral MedicineMiddle Agedmedicine.diseaseCross-Sectional StudiesCartilageCase-Control Studies030220 oncology & carcinogenesisFemalebusinessNuclear medicine
researchProduct

Fracture Mechanics of Collagen Fibrils: Influence of Natural Cross-Links

2013

AbstractTendons are important load-bearing structures, which are frequently injured in both sports and work. Type I collagen fibrils are the primary components of tendons and carry most of the mechanical loads experienced by the tissue, however, knowledge of how load is transmitted between and within fibrils is limited. The presence of covalent enzymatic cross-links between collagen molecules is an important factor that has been shown to influence mechanical behavior of the tendons. To improve our understanding of how molecular bonds translate into tendon mechanics, we used an atomic force microscopy technique to measure the mechanical behavior of individual collagen fibrils loaded to failu…

AdultMaleTailMechanical PhenomenaBiophysicsModulusFibrilta3111Collagen fibrilPatellar LigamentTensile StrengthUltimate tensile strengthmedicineAnimalsHumansMolecular Machines Motors and Nanoscale Biophysicsta315Mechanical PhenomenaChemistryFracture mechanicsta3141AnatomyHydrogen-Ion ConcentrationMiddle Agedmusculoskeletal systemTendonBiomechanical PhenomenaRatsmedicine.anatomical_structureSolubilityBiophysicsCollagenType I collagenBiophysical Journal
researchProduct