Search results for "Large"

showing 10 items of 2197 documents

Oculoectodermal syndrome: Report of a new case with a broad clinical spectrum

2014

Oculoectodermal syndrome (OMIM 600268) is rare and characterized by aplasia cutis congenita, epibulbar dermoids, and other abnormalities. We report herein on a newly recognized patient with oculoectodermal syndrome, which is the 19th reported patient with OES. The boy aged six years demonstrated a broad clinical spectrum of this condition, including aplasia cutis congenita, epibulbar dermoids, hyperkeratotic papule, mildly enlarged cisterna magna, and an enlarged fluid space in the quadrigeminal cistern, suggesting a cyst. He also manifested anomalies not reported associated with this disorder, including systematized epidermal nevus following Blaschko's lines, hypopigmented skin lesions, an…

Malemusculoskeletal diseasescongenital hereditary and neonatal diseases and abnormalitiesmedicine.medical_specialtyAplasia cutis congenitaHypopigmented skin lesionsEctodermal DysplasiaOculoectodermal syndromeGeneticsmedicineHumansCystGenetics (clinical)Dermoid CystSkinHyperkeratotic papuleHypopigmentationSystematized epidermal nevusbusiness.industryEpibulbar dermoidsBrainmedicine.diseaseMagnetic Resonance ImagingDermatologyEnlarged cisterna magnaPhenotypeChild Preschoolmedicine.symptombusinessAmerican Journal of Medical Genetics Part A
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Prognostic factors in a large multi-institutional series of papillary renal cell carcinoma.

2011

OBJECTIVES To investigate cancer-related outcomes and prognostic factors of papillary renal cell carcinoma (pRCC) in a large multicentre data set. Oncological outcome and prognostic factors of pRCC have been limitedly evaluated in comparison with the most common RCC subtype, clear cell RCC. PATIENTS AND METHODS From a multicentre retrospective database, including 5463 patients who were surgically treated for RCC at 16 Italian academic centres between 1995 and 2007, 577 patients with pRCC were identified. Univariable and multivariable Cox regression models were performed to identify prognostic factors predictive of recurrence-free survival (RFS) and cancer-specific survival (CSS) after surge…

Malerenal cell carcinomaTime FactorsPapillary renal cell carcinoma; Prognostic factorsPrognosiFEATURESkidney cancer; papillaryrenal cell carcinoma; papillary adenocarcinoma; prognostic factorspapillary renal cell carcinomaNephrectomyCLASSIFICATIONFollow-Up Studiecancer-specific survivalpapillaryRisk FactorsRetrospective StudieCause of DeathPrevalenceHumansrecurrence-free survivalprognostic factorCarcinoma Renal CellTYPE-1Proportional Hazards ModelsRetrospective StudiesNeoplasm StagingAcademic Medical Centerspapillary adenocarcinomaRisk Factorkidney cancerKidney Neoplasmprognostic factorsMiddle AgedPrognosisTUMORSKidney NeoplasmsHISTOLOGIC SUBTYPESPrognostic factors in a large multi-institutional series of papillary renal cell carcinoma.Survival RateAcademic Medical CenterItalySURVIVALProportional Hazards ModelFemaleprognostic factors; papillary renal cell carcinoma; recurrence-free survival; cancer-specific survivalFollow-Up StudiesHuman
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Export Barriers and Strategic Grouping

2007

Abstract The purpose of our work is to investigate the export strategy of international business by explicitly comparing exporting firms with non-exporting ones. This task has been undertaken by having recourse to a very large sample with more than 55,000 registered Spanish enterprises from all commercial sectors. Using this sample, we try to demonstrate that exporters and non-exporters belong to different strategic groups, with different profit levels. The existence of three kinds of barriers (managerial, organisational and external) constrains migration of non-exporting enterprises to the exporting group. However, the conclusions herein presented point at some ways of avoiding these barri…

MarketingInternationalizationCross sectorEconomicsInternational businessBusiness and International ManagementMarketingIndustrial organizationProfit (economics)Large sampleJournal of Global Marketing
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Multiplicity dependence of light (anti-)nuclei production in p–Pb collisions at sNN=5.02 TeV

2020

The measurement of the deuteron and anti- deuteron production in the rapidity range −1 < y < 0 as a function of transverse momentum and event multiplicity in p–Pb collisions at √sNN= 5.02 TeV is presented. (Anti-)deuterons are identified via their specific energy loss dE/dxand via their time-of-flight. Their production in p–Pb collisions is compared to pp and Pb–Pb collisions and is discussed within the context of thermal and coalescence models. The ratio of integrated yields of deuterons to protons (d/p) shows a significant increase as a function of the charged-particle multiplicity of the event starting from values similar to those observed in pp collisions at low multiplicities and appro…

Mass numberCoalescence (physics)PhysicsNuclear and High Energy PhysicsLarge Hadron Collider010308 nuclear & particles physicsNuclear TheoryMultiplicity (mathematics)01 natural sciencesSpectral lineNuclear physicsTime of flightDeuterium0103 physical sciencesRapidityNuclear Experiment010306 general physicsPhysics Letters B
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Effect of the height-to-diameter ratio on the mass transfer and mixing performance of a biotrickling filter

2017

BACKGROUND Biotrickling filters (BTFs) are among the most widely used biological technologies for air pollution control. The pollutant removal rate in BTFs relies to a large extent on its gas–liquid mass transfer performance. Therefore, knowledge of the design parameters affecting the mass transfer and mixing performance of full-scale BTFs is of paramount importance. RESULTS This work showed that the height-to-diameter (H/D) ratio is an important parameter in the design of BTFs devoted to air pollution control. The H/D ratio significantly affected the mass transfer and mixing performance of the BTF with and without additional stirring in the holding tank. It was observed that under the same…

Mass transfer coefficientWork (thermodynamics)Materials scienceRenewable Energy Sustainability and the EnvironmentGeneral Chemical EngineeringOrganic ChemistryMixing (process engineering)Environmental engineering02 engineering and technologyMechanics010501 environmental sciences021001 nanoscience & nanotechnology01 natural sciencesPollutionInorganic ChemistryDiameter ratioFilter (large eddy simulation)Fuel TechnologyLiquid velocityMass transferHolding tank0210 nano-technologyWaste Management and Disposal0105 earth and related environmental sciencesBiotechnologyJournal of Chemical Technology &amp; Biotechnology
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Design of a multifunctionalizable BODIPY platform for the facile elaboration of a large series of gold(i)-based optical theranostics.

2018

A simple trifunctional BODIPY platform was designed. The high potential of this platform was validated via the elaboration of twelve optical theranostics. More specifically, we reported on the synthesis, the characterization, the photophysical properties, and the evaluation of the hydrophilicity properties of the different BODIPY derivatives, as well as a theoretical rationalization of the intriguing chemical behavior of some of them. The antiproliferative evaluation and confocal imaging of the different compounds in three human and murine cancer cell lines were performed and analysed, along with the measurement of gold(I) uptake in one cancer cell line via ICP-MS.

Materials science010405 organic chemistryLarge seriesNanotechnology010402 general chemistry01 natural sciences0104 chemical sciencesInorganic Chemistrychemistry.chemical_compoundchemistryConfocal imagingBODIPYCancer cell linesHigh potentialElaborationDalton transactions (Cambridge, England : 2003)
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Turbulence structures over irregular rough surfaces

2010

Turbulent flow in a channel with irregular two-dimensional rough surfaces is analysed through wall-resolving large eddy simulation (LES). Both walls of the channel are roughened through the superimposition of sinusoidal functions having random amplitude and four different wavelengths. The downward shift of the velocity profile in the log region due to the roughness, known as roughness function, is well captured in the simulations. The spanwise and wall-normal turbulence intensities are found to increase with the roughness height, while the streamwise component decreases. The analysis of the Reynolds stress anisotropy tensor highlights a tendency towards isotropisation, confirmed by the vort…

Materials scienceComputational MechanicsGeneral Physics and Astronomyturbulence; irregular rough wall; LESSurface finishReynolds stresschannel flowSettore ICAR/01 - IdraulicaPhysics::Fluid Dynamicsirregular rough wallOpticsirregular roughneAnisotropyturbulence structureTurbulencebusiness.industryturbulenceMechanicsVorticityCondensed Matter PhysicsOpen-channel flowRoughness lengthMechanics of MaterialsLESbusinessLarge eddy simulation
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Large area perovskite light-emitting diodes by gas-assisted crystallization:

2019

Halide perovskites have been gaining considerable attention recently for use in light-emitting applications, due to their bandgap tunability, color purity and low cost fabrication methods. However, current fabrication techniques limit the processing to small-area devices. Here, we show that a facile N 2 gas-quenching technique can be used to make methylammonium lead bromide-based perovskite light-emitting diodes (PeLEDs) with a peak luminance of 6600 cd m −2 and a current efficiency of 7.0 cd A −1 . We use this strategy to upscale PeLEDs to large-area substrates (230 cm 2 ) by developing a protocol for slot-die coating combined with gas-quenching. The resulting large area devices (9 device…

Materials scienceFabricationBand gapSlot-die coatings02 engineering and technologySubstrate (electronics)Large area devicesengineering.material010402 general chemistry01 natural sciencesLuminancelaw.inventionCoatinglawQuenchingMaterials ChemistryMaterialsDiodePerovskite (structure)Industrial Innovationbusiness.industryGeneral Chemistry021001 nanoscience & nanotechnologyPerovskite light emitting diodes0104 chemical sciencesLuminanceManufacturing techniquesHalide perovskitesengineeringOptoelectronics0210 nano-technologybusinessLight-emitting diode
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The CERN/ISOLDE Laser Ion Source

2017

Laser resonance photo-ionization an essential aspect of radioactive ion beam production for fundamental and applied physics research. The laser ion source of the ISOLDE facility, described here, is the most versatile of its type worldwide.

Materials scienceLarge Hadron ColliderApplied physicsIon beambusiness.industry02 engineering and technology021001 nanoscience & nanotechnologyLaser01 natural sciencesIon sourcelaw.invention010309 opticsOpticslaw0103 physical sciencesPhysics::Accelerator PhysicsLaser resonancePhysics::Atomic PhysicsNuclear Experiment0210 nano-technologybusinessLaser beamsConference on Lasers and Electro-Optics
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The manipulation of ions using electromagnetic traps

1992

Electromagnetic traps, in addition to providing very clean and gentle confinement for very precise and sensitive observation of charged particles, are very versatile devices for collecting and preparing charged particles from outside sources for observation by devices which are also outside, devices which may in themselves be other electromagnetic traps. This paper introduces the basic principles of using electromagnetic traps for collecting and cooling and presents some preliminary test results from using Paul traps for these purposes. Specifically, in relatively modest Paul traps with 28 mm between end electrodes a collection efficiency of 0.2% was achieved for a 60 keV DC beam of 132Xe i…

Materials scienceLarge Hadron Colliderbusiness.industryCondensed Matter PhysicsAtomic and Molecular Physics and OpticsCharged particleIonBooster (electric power)ElectrodeOptoelectronicsPhysics::Atomic PhysicsIon trapAtomic physicsbusinessMathematical PhysicsPhysica Scripta
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