Search results for "Lebanon"

showing 10 items of 33 documents

Phytochemical Analysis and Cytotoxicity Towards Multidrug-Resistant Leukemia Cells of Essential Oils Derived from Lebanese Medicinal Plants

2012

Juniperus excelsa fruit essential oil as well as J. oxycedrus, Cedrus libani, and Pinus pinea wood essential oils have been obtained with yields between 2.2 ± 0.3 % to 3.4 ± 0.5 % and analyzed by gas chromatography. Sesquiterpenes mainly characterized C. libani and J. oxycedrus essential oils, while in P. pinea and J. excelsa, monoterpenes were the most abundant compounds. In J. oxycedrus, cis-calamenene (7.8 %), cuparene (3.8 %), and cis-thujopsenal (2.0 %) have been detected for the first time. The cytotoxic activity of these essential oils against drug-sensitive CCRF-CEM and multidrug-resistant P-glycoprotein-expressing CEM/ADR5000 leukemia cells has been investigated (IC₅₀ values: 29.46…

Cupressaceaegas chromatographyPharmaceutical ScienceAnalytical Chemistrylaw.inventionlawDrug DiscoveryTumor Cells CulturedLebanonMedicinal plantsLeukemiabiologyTraditional medicinePinaceaeWoodDrug Resistance MultiplePhytochemicalJuniperus excelsaPinaceaeMolecular MedicineSesquiterpenesJuniperus oxycedruscancer; essential oils; gas chromatography; multidrug resistance; Juniperus excelsa; Juniperus oxycedrus; Cupressaceae; Cedrus libani; Pinus pinea; PinaceaeNOmultidrug resistanceBotanyOils VolatileHumanscancerCedrusessential oilsEssential oilCedrus libaniPharmacologyPlants MedicinalOrganic ChemistryCupressaceaePinusbiology.organism_classificationCedrus libaniAntineoplastic Agents PhytogenicComplementary and alternative medicineDrug Resistance NeoplasmFruitJuniperusMonoterpenesPinus pineaJuniperus excelsaJuniperus oxycedrusPhytotherapyPlanta Medica
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Associations of nutrition and body composition with cardiovascular disease risk factors in soldiers during a 6-month deployment

2020

Objectives This observational follow-up study investigated the associations of nutrition and body composition with cardiovascular disease (CVD) risk factors, including pro-inflammatory biomarkers, in soldiers during a 6-month deployment. Material and Methods Thirty-five male soldiers were assessed at months 0, 3 and 6, and their parameters, i.e., M±SD, were as follows: age 30.0±8.7 years, height 179±6 cm, and BMI 24.2±2.5 kg/m 2 . Three-day food diaries were used for monitoring macronutrient intake. Body composition was estimated using bioimpedance. Fasting blood samples for lipids and pro-inflammatory biomarkers were collected, and blood pressure measurements were performed. Results Carboh…

Dietary FiberMaleSYMPTOMSkolesteroliPhysical fitness0211 other engineering and technologieslcsh:MedicinePROTEINBlood lipidsPhysiologyBLOOD-PRESSURE02 engineering and technologyruokavaliotBody fat percentagesoldierchemistry.chemical_compoundFiber intakeRisk FactorsMedicinesotilaatLebanonFinland05 social sciencesblood pressureGeneral MedicinerauhanturvaoperaatiotDiet Records3142 Public health care science environmental and occupational health0506 political sciencebody fatMilitary PersonnelAdipose TissueCardiovascular DiseasesLow-density lipoproteinBody CompositionSERUM-LIPIDSComposition (visual arts)3143 NutritionAdultPHYSICAL-FITNESS050601 international relationsINFLAMMATIONterveysvaikutuksetHumanscrisis managementkehonkoostumus021110 strategic defence & security studiesCholesterolbusiness.industryterveydentilalcsh:RPublic Health Environmental and Occupational HealthcholesterolCholesterol LDLfiber intakeDietverenpaineBlood pressurechemistryFATravintokuitubusinessInternational Journal of Occupational Medicine and Environmental Health
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Constituents of leaves and flowers essential oils of Helichrysum pallasii (Spreng.) Ledeb. growing wild in Lebanon.

2009

The chemical compositions of the essential oils obtained from leaves and flowers of Helichrysum pallasii were analyzed by gas chromatography and gas chromatography-mass spectrometry. Among the 102 identified constituents, hexadecanoic acid (16.2%), (Z,Z)-9,12-octadecadienoic acid (6.8%), tetradecanoic acid (2.6%), and (Z)-caryophyllene (4.2%) were the main constituent of the oil from leaves, while in the oil from flowers hexadecanoic acid (14.7%), (Z,Z)-9,12-octadecadienoic acid (14.2%), (Z)-caryophyllene (3.6%), and delta-cadinene (3.1%) predominated. The oils were both characterized by sesquiterpenes (33.4% for leaves and 33.7% for flowers, respectively) and fatty acids and esters (30.3% …

Helichrysum pallasii (Spreng.) Ledeb.Palmitic AcidMedicine (miscellaneous)Myristic acidFlowersMyristic Acidlaw.inventionPalmitic acidMinimum inhibitory concentrationchemistry.chemical_compoundlawBotanyOils VolatileStaphylococcus epidermidisPlant OilsFood scienceLebanonEssential oilHelichrysumPolycyclic SesquiterpenesNutrition and DieteticsbiologyBacteriaPlant ExtractsAnti-Inflammatory Agents Non-SteroidalFatty AcidsEstersAsteraceaebiology.organism_classificationAnti-Bacterial AgentsPlant LeaveschemistryHelichrysumFatty Acids UnsaturatedStearic acidGas chromatographySesquiterpenesJournal of medicinal food
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New chronology for Ksâr ‘Akil (Lebanon) supports Levantine route of modern human dispersal into Europe

2015

Modern human dispersal into Europe is thought to have occurred with the start of the Upper Paleolithic around 50,000-40,000 y ago. The Levantine corridor hypothesis suggests that modern humans from Africa spread into Europe via the Levant. Ksâr 'Akil (Lebanon), with its deeply stratified Initial (IUP) and Early (EUP) Upper Paleolithic sequence containing modern human remains, has played an important part in the debate. The latest chronology for the site, based on AMS radiocarbon dates of shell ornaments, suggests that the appearance of the Levantine IUP is later than the start of the first Upper Paleolithic in Europe, thus questioning the Levantine corridor hypothesis. Here we report a seri…

HistorygastropodHuman MigrationPhorcus turbinatusNew ChronologySocial SciencesOxygen IsotopesAncient historyAncientradiometric datinglaw.inventionModern human dispersalPaleolithicCavelawZooarcheologyHumansPhorcus turbinatusskeletonCarbon RadioisotopeshumanRadiocarbon datingAmino AcidsLebanonUpper paleolithicgeographyfossilMultidisciplinarygeography.geographical_feature_categorybiologyChronology; Modern human dispersal; Near east; Upper paleolithic; Zooarcheology; Africa; Amino Acids; Bayes Theorem; Carbon Radioisotopes; Europe; History Ancient; Humans; Lebanon; Oxygen Isotopes; Stereoisomerism; Human Migration; Multidisciplinary; Medicine (all)Medicine (all)articleBayes TheoremStereoisomerismchronologybiology.organism_classificationArchaeologypopulation dispersalEuropepriority journalAfricaNear eastUpper PaleolithicmaxillaBiological dispersalhypothesisAurignacianChronologyProceedings of the National Academy of Sciences
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Characterisation of the essential oil of Nepeta glomerata Montbret et Aucher ex Bentham from Lebanon and its biological activities.

2011

The essential oil of Nepeta glomerata from Lebanon was studied by means of GC and GC/MS analysis; 70 compounds were identified. The oil was constituted mainly by monoterpenes and the most abundant components were α-pinene, spathulenol and carvacrol. Nepeta glomerata oil showed antibacterial activity, particularly towards Gram-positive bacteria, and also inhibited LPS-induced NO production in macrophage cell line RAW 264.7, with an IC(50) value of 78.1 µg mL(-1). Furthermore, an in vitro cytotoxic assay showed that the oil was more active on a renal adenocarcinoma cell line (48% of inhibition of proliferation at 100 µg mL(-1)) in comparison to an amelanotic melanoma.

LipopolysaccharidesPlant ScienceMicrobial Sensitivity TestsNitric OxideBiochemistryAnalytical Chemistrylaw.inventionchemistry.chemical_compoundMicelawNepetaCell Line TumorBotanyOils VolatileAnimalsHumansCarvacrolNo productionLebanonEssential oilbiologyOrganic ChemistryMs analysisbiology.organism_classificationAnti-Bacterial AgentschemistryMonoterpenesNepetaRenal adenocarcinomaDrug Screening Assays AntitumorAntibacterial activityBacteriaNatural product research
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Antispasmodic Effects and Structure−Activity Relationships of Labdane Diterpenoids from Marrubium globosum ssp. libanoticum

2009

Marrubium globosum ssp. libanoticum is a medicinal plant used in Lebanon to reduce pain and smooth muscle spasms. A chloroform extract obtained from M. globosum aerial parts reduced acetylcholine-induced contractions in the isolated mouse ileum. The purification of this extract identified, among 12 isolated labdane diterpenoids, four new compounds, named 13-epicyllenin A (4), 13,15-diepicyllenin A (5), marrulibacetal (9), and marrulactone (11). Their structures were determined by spectroscopic methods. Compound 9, which exerted antispasmodic activity, is likely the active ingredient of the extract. Preliminary structure-activity relationships for this class of compounds are suggested.

MaleAntispasmodic effectditerpenoidPharmaceutical SciencePharmacognosyAnalytical ChemistryLabdaneMiceStructure-Activity Relationshipchemistry.chemical_compoundIleumDrug DiscoveryBotanymedicineAnimalsLebanonMedicinal plantsPharmacologyMarrubium globosum ssp. libanoticumPlants MedicinalMolecular StructurebiologyPlant ExtractsfungiOrganic ChemistryParasympatholyticsfood and beveragesMuscle SmoothSettore CHIM/06 - Chimica Organicabiology.organism_classificationAcetylcholineTerpenoidAntispasmodic AgentComplementary and alternative medicinechemistryMolecular MedicineAntispasmodicDiterpenesDiterpeneMarrubiumMarrubiummedicine.drugJournal of Natural Products
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Evaluation of occupational physical load during 6-month international crisis management operation

2018

Objectives Generally, operational military duties are associated with a variety of stressors, such as prolonged physical activity (PA). However, limited information is available on the occupational workload or changes in PA during international military operations. Thus, the aim of the study was to investigate the changes in body composition, stress biomarkers, PA, and heart rate (HR) responses of 79 male soldiers during a 6-month international crisis management operation. Material and Methods Measurements were conducted 3 times in South-Lebanon during the operation. Body composition was assessed by the bioelectrical impedance method. Blood samples were analyzed for serum testosterone, sex-…

MaleSalivaHydrocortisone0211 other engineering and technologieslcsh:Medicine02 engineering and technologyworkload0302 clinical medicineSex hormone-binding globulinHeart RateSex Hormone-Binding GlobulinTestosteronesotilaatLebanonta315TestosteroneFinlandphysical exertionbiologyGeneral Medicineta3142Body CompositionBioelectrical impedance analysisWorking environmentAdultmedicine.medical_specialtyfyysinen rasitustyömäärä03 medical and health sciencesSomatomedinsStress PhysiologicalInternal medicineHeart ratemedicineaccelerometryHumanssotilaslääketiedeExertionSalivaExercise021110 strategic defence & security studiesbusiness.industrytyöterveysrauhanturvaajatlcsh:RPublic Health Environmental and Occupational Health030229 sport sciencesfyysinen kuormittavuusEndocrinologyPhysical loadsotilashenkilöstöoccupational healthbiology.proteinPhysical therapymilitary personnelalpha-Amylasesbusinessmilitary medicineInternational Journal of Occupational Medicine and Environmental Health
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Lebanon and Egypt: The construction of a vital space in women’s writing

2023

This paper try to outline the developments of the literary production of the Mashriq, departing from a gender perspective. Approaching the female literary universe of Lebanon and Egypt entails referring to cultural contexts in which women have historically suffered forms of exclusion and marginalisation, when not outright oppression, and in which solidly patriarchal and hierarchical family structures have often found in religious faith an alibi which justifies and facilitates the perpetration and diffusion of such discrimination. In this context literary writing plays a fundamental role: having been long described and interpreted by the male literary world, women begin to speak their truth …

Mashriq Lebanon Egypt Gender Literature French-speaking literatureSettore L-FIL-LET/14 - Critica Letteraria E Letterature Comparate
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PERCORSI DI ESEGESI CORANICA : per un rinnovamento del pensiero islamico contemporaneo

2019

Muhammad Hussein Fadlallah è stato uno degli intellettuali di punta dello sciismo imamita del XX secolo, e si colloca in quella scuola di pensiero e azione che, a partire da 'Ali Shariati e passando per Baqir al-Sadr e Musa al-Sadr, ha illustrato íl pensiero sciita contemporaneo. La pubblicazione di questa antologia commentata degli scritti di Fadlallah risulta particolarmente opportuna nel quarantennale della rivoluzione iraniana di Khomeini. Convinto della necessità che la scienza si trasformi in abbrivio all'azione, la tesi capitale di Fadlallah è che l'Islam rifiuta il quietismo e incita alla ribellione, poiché è íl Corano stesso che mobilita gli oppressi secondo il principio della pote…

Muhammad Hussein Fadlallah Sciismo LibanoSettore L-OR/10 - Storia Dei Paesi IslamiciMuhammad Hussein Fadlallah Shi'ism Lebanon
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Volatile constituents of Stachys palaestina L. (Palestine woundwort) growing in Lebanon

2014

The hydrodistillation of the aerial parts of Stachys palaestina L. collected in Lebanon in the Kadisha Valley, yielded 0.1% (w/w) of essential oil. GC and GC-MS analyses enabled the identification of 87 compounds representing 90.8% of the total oil. Hexadecanoic acid (10%), hexahydrofarnesyl acetone (6.9%), eugenol (4.3%) and (E)-caryophyllene (4.3%) were the main components. On the whole, the oil was constituted mainly of sesquiterpenes (37.7%), among which sesquiterpene hydrocarbons (20.7%) slightly prevailed over oxygenated sesquiterpenes (17.0%). This is the first report on the chemical composition of S. palaestina essential oil.

Palmitic AcidPlant ScienceSesquiterpeneBiochemistryhexahydrofarnesylacetoneAnalytical Chemistrylaw.invention(E)-caryophyllenechemistry.chemical_compoundlawessential oilBotanyEugenolAcetoneOils VolatileStachys palaestinaPalestineLebanonChemical compositionEssential oileugenolPolycyclic SesquiterpenesbiologyTerpenesOrganic ChemistryStachysPlant Components Aerialbiology.organism_classificationhexadecanoic acidEugenolchemistryStachysSesquiterpenes
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