Search results for "Lee"
showing 10 items of 1847 documents
Respiratory gas exchange in the rat spleen in situ and intrasplenic oxyhemoglobin saturation.
1979
Measurements of splenic respiratory gas exchange and of HbO2 saturations in the red pulp of the rat spleen have shown that there are no indications of a reduced intrasplenic O2 availability during normoxia. The present studies provide evidence that, in the normal spleen, the intrasplenic sequestration of red blood cells cannot be explained by an O2 deficiency in the red pulp since the commonly accepted notion of an intrasplenic hypoxia is not true.
SHIPPING 4.0: GENERAL FRAMEWORK FOR A NEW CYBERSHIPPING ERA
2019
The fourth industrial revolution, also referred to as Industry 4.0, is a disruptive transformation process aimed which, by means of digital technologies, is substantially innovating the value creation processes in all industry contexts. With such premise, industry 4.0 is in particular expected to have a substantial impact on the maritime transport and shipping sectors, where smart ships and autonomous vessels are expected to be the building blocks of a new interconnected maritime ecosystem. The application of Industry 4.0 principles to the shipping domain (Shipping 4.0) has thus raised a scientific debate about the efficiency, sustainability, and safety of maritime transport. Recent researc…
The role of reactive oxygen species in obesity therapeutics.
2019
Obesity is a major risk factor for multiple severe health conditions, including cardiovascular diseases, diabetes and cancer. It is often related to an increased risk of morbidity and mortality and, as it can be accompanied by non-fatal health problems, quality of life is seriously reduced due to related conditions including hypertension, sleep apnea, osteoarthritis, respiratory problems and infertility. Evidence suggests that oxidative stress is related to obesity and its complications. In obese patients, there is an increase in levels of reactive oxygen species and nitrogen species and antioxidant defenses are undermined in comparison to normal-weight counterparts. In addition, these para…
Mechanical ventilation and Streptococcus pneumoniae pneumonia alter mitochondrial homeostasis.
2018
Abstract Required mechanical ventilation (MV) may contribute to bacterial dissemination in patients with Streptococcus pneumoniae pneumonia. Significant variations in plasma mitochondrial DNA (mtDNA) have been reported in sepsis according to the outcome. The impact of lung stretch during MV was addressed in a model of pneumonia. Healthy or S. pneumoniae infected rabbits were submitted to MV or kept spontaneously breathing (SB). Bacterial burden, cytokines release, mitochondrial DNA levels, integrity and transcription were assessed along with 48-hour mortality. Compared with infected SB rabbits, MV rabbits developed more severe pneumonia with greater concentrations of bacteria in the lungs, …
Splenic Graulomatosis
2015
Learning objectives Background Findings and procedure details Conclusion Personal information References
Modelling and forecasting mortality in Spain
2008
[EN] Experience shows that static life tables overestimate death probabilities. As a consequence of this overestimation the premiums for annuities, pensions and life insurance are not what they actually should be, with negative effects for insurance companies or policy-holders. The reason for this overestimation is that static life tables, through being computed for a specific period of time, cannot take into account the decreasing mortality trend over time. Dynamic life tables overcome this problem by incorporating the influence of the calendar when graduating mortality. Recent papers on the topic look for the development of new methods to deal with this dynamism. Most methods used in dyna…
Information Transfer Between Respiration and Heart Rate During Sleep Apnea
2016
It is well-known that sleep apnea affects the respiration and the heart rate (HR), and studies have shown that the cardiorespiratory coupling is also compromised during obstructive sleep apnea (OSA). Furthermore, the classification of hypopneas is challenging, in particular when only ECG-derived features are used. In this context, this study investigates how different ECG-derived respiratory (EDR) signals resemble the respiratory effort during different types of apneas, and how the amount of information transferred from respiration to HR varies according to the respiratory signal used, real or ECG-derived. ECG and respiratory signals of 10 patients suffering from sleep apnea were analysed, …
Assessment of Cardiorespiratory Interactions during Apneic Events in Sleep via Fuzzy Kernel Measures of Information Dynamics
2021
Apnea and other breathing-related disorders have been linked to the development of hypertension or impairments of the cardiovascular, cognitive or metabolic systems. The combined assessment of multiple physiological signals acquired during sleep is of fundamental importance for providing additional insights about breathing disorder events and the associated impairments. In this work, we apply information-theoretic measures to describe the joint dynamics of cardiorespiratory physiological processes in a large group of patients reporting repeated episodes of hypopneas, apneas (central, obstructive, mixed) and respiratory effort related arousals (RERAs). We analyze the heart period as the targ…
Oral Communication
2012
Inherited factor VII (FVII) deficiency is the most common of the rare autosomal recessive bleeding disorders (RBD), with an estimated prevalence of 1 per 300,000 in European countries.1,2 It is likely that the prevalence is higher in those countries where consanguineous marriages are frequent.We here report STER study results on 112 evaluable enrolled cases
Innowacyjne rozwiązania w logistyce transportu
2016
The article discusses the main issues of innovative solutions for transportation, which affect the maximization of companies’ profits. The article pointed out the multitude of technological advances that due to its scope will cover all modes of transport. The author tried to show the most interesting, sometimes even futuristic solutions, which today’s realization is impossible, but in the near future they might contribute to revolutionization of the transportation market.