Search results for "Lies"
showing 10 items of 1093 documents
Clinical whole-exome sequencing for the diagnosis of rare disorders with congenital anomalies and/or intellectual disability: substantial interest of…
2017
International audience; PurposeCongenital anomalies and intellectual disability (CA/ID) are a major diagnostic challenge in medical genetics—50% of patients still have no molecular diagnosis after a long and stressful diagnostic “odyssey.” Solo clinical whole-exome sequencing (WES) was applied in our genetics center to improve diagnosis in patients with CA/ID.MethodsThis retrospective study examined 416 consecutive tests performed over 3 years to demonstrate the effectiveness of periodically reanalyzing WES data. The raw data from each nonpositive test was reanalyzed at 12 months with the most recent pipeline and in the light of new data in the literature. The results of the reanalysis for …
Proteomics Reveals the Potential Protective Mechanism of Hydrogen Sulfide on Retinal Ganglion Cells in an Ischemia/Reperfusion Injury Animal Model
2020
Glaucoma is the leading cause of irreversible blindness and is characterized by progressive retinal ganglion cell (RGC) degeneration. Hydrogen sulfide (H2S) is a potent neurotransmitter and has been proven to protect RGCs against glaucomatous injury in vitro and in vivo. This study is to provide an overall insight of H2S&rsquo
The influence of tin compounds on the dynamic properties of liposome membranes: A study using the ESR method
2005
AbstractThe influence of organic and inorganic compounds of tin on the dynamic properties of liposome membranes obtained in the process of dipalmitoylphosphatidylcholine (DPPC) sonication in distilled water was investigated. This was carried out by means of the spin ESR probe method. The probes were selected in such a way as to penetrate different areas of the membrane (a TEMPO probe, 5-DOXYL stearic acid, 16-DOXYL stearic acid). Four compounds of tin were chosen: three organic ones, (CH3)4Sn, (C2H5)4Sn and (C3H7)3SnCl, and one inorganic one, SnCl2. The investigated compounds were added to a liposome dispersion, which was prepared prior to that. The concentration of the admixture was change…
The usefulness of a mathematical model of exposure for environmental risk assessment
2011
We respond to the Comment of Lang et al . [[1][1]] regarding our mathematical model [[2][2]] of exposure of non-target Lepidoptera to Bt -maize pollen expressing Cry1Ab within Europe. Lang et al . remark on the degree to which the model was subject to uncertainty. Perry et al . [[2][2]] did indeed
A mathematical model of exposure of nontarget Lepidoptera to Bt-maize pollen expressing Cry1Ab within Europe
2010
Genetically modified (GM) maize MON810 expresses a Cry1Ab insecticidal protein, derived from Bacillus thuringiensis ( Bt ), toxic to lepidopteran target pests such as Ostrinia nubilalis . An environmental risk to non-target Lepidoptera from this GM crop is exposure to harmful amounts of Bt -containing pollen deposited on host plants in or near MON810 fields. An 11-parameter mathematical model analysed exposure of larvae of three non-target species: the butterflies Inachis io (L.), Vanessa atalanta (L.) and moth Plutella xylostella (L.), in 11 representative maize cultivation regions in four European countries. A mortality–dose relationship was integrated with a dose–distance relationship t…
Lamotrigine use in pregnancy and risk of orofacial cleft and other congenital anomalies
2016
Objective: To test previous signals of a risk of orofacial cleft (OC) and clubfoot with exposure to the antiepileptic lamotrigine, and to investigate risk of other congenital anomalies (CA).Methods: This was a population-based case–malformed control study based on 21 EUROCAT CA registries covering 10.1 million births (1995–2011), including births to 2005 in which the clubfoot signal was generated and a subsequent independent study population of 6.3 million births. A total of 226,806 babies with CA included livebirths, stillbirths, and terminations of pregnancy following prenatal diagnosis. First-trimester lamotrigine monotherapy exposure in OC cases and clubfoot cases was compared to other …
Physico-chemical investigation of the state of cyanamide confined in AOT and lecithin reversed micelles
2004
Sodium bis(2-ethylhexyl)sulfosuccinate (AOT) and lecithin reversed micelles containing cyanamide have been investigated by small-angle X-ray scattering, FT-IR, and 1H NMR spectroscopy at various cyanamide-to-surfactant molar ratio (X) and at fixed surfactant concentration (0.1 mol kg-1). Experimental data are consistent with a model of cyanamide molecules confined in reversed micelles, quite uniformly distributed among them and mainly located among surfactant headgroups. SAXS data analysis leads also to hypothesize a unidimensional growth of the reversed micelles with increasing the X value. Moreover, the cyanamide state and the cyanamide/cyanamide interactions in reversed micelles have bee…
The first COVID-19 lockdown reveals an ambivalent relation of French parents with food pleasure: the struggle to find a balance
2021
International audience; In France, a first COVID-19 lockdown took place from March-May 2020. Using an online survey including three open-ended questions, this study explored parents' experiences regarding changes in their family's eating behaviors during this lockdown. French parents (n = 498, 71% mothers) of young children were invited to describe which food-related changes they (1) perceived as positive during the lockdown, (2) perceived as negative, and (3) would like to maintain after the lockdown. A thematic analysis revealed that parents appreciated the choice of more local, fresh and high-quality foods, the time to prepare foods (homemade dishes, new recipes) and cooking and eating w…
"Table 2" of "Measurement of the inclusive jet cross-section in p anti-p collisions at s**(1/2) =1.96-TeV"
1970
Measured inclusive jet cross section as a function of jet transverse momentum for absolute values of the jet rapidity from 0.4 to 0.8 for cone radius R = 0.7.
"Table 6" of "Measurement of the inclusive jet cross-section in p anti-p collisions at s**(1/2) =1.96-TeV"
1970
Measured inclusive jet cross section as a function of jet transverse momentum for absolute values of the jet rapidity from 2.0 to 2.4 for cone radius R = 0.7.