Search results for "Linkage"
showing 10 items of 363 documents
Bagging, bumping, multiview, and active learning for record linkage with empirical results on patient identity data
2011
Record linkage or deduplication deals with the detection and deletion of duplicates in and across files. For this task, this paper introduces and evaluates two new machine-learning methods (bumping and multiview) together with bagging, a tree-based ensemble-approach. Whereas bumping represents a tree-based approach as well, multiview is based on the combination of different methods and the semi-supervised learning principle. After providing a theoretical background of the methods, initial empirical results on patient identity data are given. In the empirical evaluation, we calibrate the methods on three different kinds of training data. The results show that the smallest training data set, …
Late Cardiac Events after Childhood Cancer: Methodological Aspects of the Pan-European Study PanCareSurFup.
2016
Background and AimChildhood cancer survivors are at high risk of long-term adverse effects of cancer and its treatment, including cardiac events. The pan-European PanCareSurFup study determined the incidence and risk factors for cardiac events among childhood cancer survivors. The aim of this article is to describe the methodology of the cardiac cohort and nested case-control study within PanCareSurFup.MethodsEight data providers in Europe participating in PanCareSurFup identified and validated symptomatic cardiac events in their cohorts of childhood cancer survivors. Data on symptomatic heart failure, ischemia, pericarditis, valvular disease and arrhythmia were collected and graded accordi…
Genome-wide significant association between alcohol dependence and a variant in the ADH gene cluster
2011
Alcohol dependence (AD) is an important contributory factor to the global burden of disease. The etiology of AD involves both environmental and genetic factors, and the disorder has a heritability of around 50%. The aim of the present study was to identify susceptibility genes for AD by performing a genome-wide association study (GWAS). The sample comprised 1333 male in-patients with severe AD according to the Diagnostic and Statistical Manual of Mental Disorders, 4th edition, and 2168 controls. These included 487 patients and 1358 controls from a previous GWAS study by our group. All individuals were of German descent. Single-marker tests and a polygenic score-based analysis to assess the …
Impact of the position isomer of the linkage in the double D–A branch-based organic dyes on the photovoltaic performance
2014
Abstract Three organic dyes with double D–A system were synthesized and applied in the dye-sensitized solar cells. These dyes contain phenothiazine as an electron donor and cyanoacetic acid as an acceptor/anchor. Linkages were incorporated at the ortho-, meta- and para-positions and their impact on the performance of photovoltaic was observed. Among them, the dye with a para-position linkage exhibited the highest short-circuit photocurrent density (12.26 mA cm−2) and open-circuit photovoltage (756 mV), leading to the best overall efficiency (6.14%) due to better light harvesting capacity under standard global 1.5 AM conditions. Under similar measuring conditions the dyes with ortho and meta…
Spanning Trees and bootstrap reliability estimation in correlation based networks
2007
We introduce a new technique to associate a spanning tree to the average linkage cluster analysis. We term this tree as the Average Linkage Minimum Spanning Tree. We also introduce a technique to associate a value of reliability to links of correlation based graphs by using bootstrap replicas of data. Both techniques are applied to the portfolio of the 300 most capitalized stocks traded at New York Stock Exchange during the time period 2001-2003. We show that the Average Linkage Minimum Spanning Tree recognizes economic sectors and sub-sectors as communities in the network slightly better than the Minimum Spanning Tree does. We also show that the average reliability of links in the Minimum …
722: Maternal solid organ transplantation and pregnancy outcome; a national population-based cohort study
2013
outcome; a national population-based cohort study Nils-Halvdan Morken, Cesar Diaz-Garcia, Mats Brannstrom University of Bergen, Public Health and Primary Health care, Bergen, Norway, University of Valencia, Gynecology and Obstetrics, Valencia, Spain, University of Gothenburg, Obstetrics and Gynecology, Valencia, Sweden OBJECTIVE: The first pregnancy with a live birth after solid organ transplantation in the human occurred more than 50 years ago. Still, knowledge about this very special patient group is limited. The objective was to assess the risk of adverse pregnancy outcome after transplant compared to pregnancies before transplant in females. We also compared the risk after transplant wi…
Linkage analysis and disease models in benign familial infantile seizures: a study of 16 families.
2006
Summary: Purpose: Benign familial infantile seizures (BFIS) is a genetically heterogeneous condition characterized by partial seizures, onset age from 3 to 9 months, and favorable outcome. BFIS loci were identified on chromosomes 19q12-13.1 and 16p12-q12, allelic to infantile convulsions and choreathetosis. The identification of SCN2A mutations in families with only infantile seizures indicated that BFNIS and BFIS may show overlapping clinical features. Infantile seizures also were in a family with familial hemiplegic migraine and mutations in the ATP1A2 gene. We have examined the heterogeneous genetics of BFIS by means of linkage analysis. Methods: Sixteen families were examined. Probands …
Genetic heterogeneity in ADHD: DAT1 gene only affects probands without CD
2008
Contains fulltext : 70183.pdf (Publisher’s version ) (Closed access) Previous studies have found heterogeneous association between DAT1-3'-UTR-VNTR and attention deficit hyperactivity disorder (ADHD). Various proportions of conduct disorder (CD) comorbidity in their ADHD samples may partially explain the observational discrepancies. Evidence for this comes from family and twin studies which found ADHD probands with CD (ADHD + CD) are genetically different from those without CD (ADHD - CD). Genotypes of 20 DAT1 markers were analyzed in 576 trios, consisting of 141 ADHD + CD and 435 ADHD - CD. In addition to the classical TDT test, a specific genetic heterogeneity test was performed to identi…
Tourism planning and innovation: The Caribbean under the spotlight
2018
International audience; The importance of the islands working together toward a multicentre product for tourists has been highlighted asearly as the 1980s, and yet hardly anything has been done in that sense. Can cluster be considered as the wayforward for the sustainable development of the Caribbean? This question could be considered as the first step ofthe tourism planning process. Hierarchical method or linkage method that works by identifying entities thatmatch each other based on the investigator selection of similar attribute categories is the most suitable clusteringapproach for the Caribbean. Despite the fact that cluster appears as a potential solution for issues faced by someCarib…
Peran Sektor Pertanian Arti Luas dalam Perekonomian Papua (Pendekatan Model Input-Output)
2018
The aim of this study is to know contribution of agriculture sectors on Gross Domestic Product of Papua in 2002 based on input-output table analysis. The result of analyzing shows that contribution of agriculture sectors in broad meaning to Gross Domestic Regional Product of Papua about 20,11% . Based on backward linkage analysis, it describes that plantations subsector; animal husbandry subsector and fishery subsector have an increase number in backward linkage, on the other hand backward linkage of food crops goes down. Furthermore, forward linkage of agriculture sectors which have link with others sector is fall in 2002. In conclusion, contribution of agriculture setors on Gross Domestic…