Search results for "Lip"

showing 10 items of 8306 documents

A new and versatile method for iodofunctionalization of 1,3-dienes

1986

Abstract We wish to report the reactions of conjugated dienes with I(py) 2 BF 4 . This simple and general method allows the regiospecific 1,2-addition of iodine and a nucleophile to terminal dienes and the 1,4-addition to internal dienes.

Addition reactionchemistry.chemical_compoundGeneral methodNucleophileChemistryOrganic ChemistryDrug DiscoveryPyridineHalogenationOrganic chemistryConjugated systemAliphatic compoundBiochemistryTetrahedron Letters
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The visceral adiposity index is associated with insulin sensitivity and IGF-I levels in adults with growth hormone deficiency

2016

The visceral adiposity index, based on anthropometric and metabolic parameters, has been shown to be related to adipose tissue function and insulin sensitivity. We aimed to evaluate the performance of the visceral adiposity index in adult patients with growth hormone deficiency. We enrolled 52 patients(mean age 51 ± 13 years) with newly diagnosed growth hormone deficiency and 50 matched healthy subjects as controls at baseline. At baseline and after 12 and 24 months of treatment we evaluated anthropometric measures, lipid profile, glucose and insulin during an oral glucose tolerance test, hemoglobin A1c, homeostasis model assessment estimate of insulin resistance, quantitative insulin sensi…

AdenomaAdultMalemedicine.medical_specialtyEndocrinology Diabetes and Metabolismmedicine.medical_treatmentAdipose tissue030209 endocrinology & metabolism030204 cardiovascular system & hematologyGrowth hormone deficiencySettore MED/13 - Endocrinologia03 medical and health sciences0302 clinical medicineEndocrinologyInsulin resistanceInternal medicineDiabetes mellitusmedicineHumansPituitary NeoplasmsInsulin-Like Growth Factor IDwarfism PituitaryAdiposityAgedmedicine.diagnostic_testbusiness.industryInsulinQuantitative insulin sensitivity check indexMiddle Agedmedicine.diseaseGrowth hormone treatmentEndocrinologygrowth hormoneFemaleInsulin ResistanceWaist CircumferencebusinessLipid profile
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Myxoid lipoadenorna of the parathyroid gland

1980

A myxoid lipoadenoma of the parathyroid gland causing primary hyperparathyroidism is reported. The very rare and histologically unusual tumor consists of an epithelial component which is combined with a stromal component in a characteristic way. Slender, irregularly branched trabeculae which mainly consist of chief cells as well as a few oxyphil cells are found as epithelial component. The predominantly myxomatous and only focally lipomatous stromal component is interpreted as an integrated tumor component of the lipoadenoma which is derived from the parathyroid adipose tissue.

AdenomaMaleHyperparathyroidismmedicine.medical_specialtyPathologyStromal cellAdenomaParathyroid neoplasmHyperparathyroidismAdipose tissueCell BiologyMiddle AgedBiologymedicine.diseasePathology and Forensic MedicineParathyroid Neoplasmsmedicine.anatomical_structureLipoadenomaEndocrinologyInternal medicinemedicineHumansParathyroid glandPrimary hyperparathyroidismPathology - Research and Practice
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Age affects myosin relaxation states in skeletal muscle fibers of female but not male mice

2018

The recent discovery that myosin has two distinct states in relaxed muscle–disordered relaxed (DRX) and super-relaxed (SRX)–provides another factor to consider in our fundamental understanding of the aging mechanism in skeletal muscle, since myosin is thought to be a potential contributor to dynapenia (age-associated loss of muscle strength independent of atrophy). The primary goal of this study was to determine the effects of age on DRX and SRX states and to examine their sex specificity. We have used quantitative fluorescence microscopy of the fluorescent nucleotide analog 2′/3′-O-(N-methylanthraniloyl) ATP (mantATP) to measure single-nucleotide turnover kinetics of myosin in skinned skel…

Adenosine TriphosphataseMale0301 basic medicineAgingMuscle PhysiologyPhysiologyMuscle RelaxationATPaseMuscle Fibers Skeletallcsh:MedicineMale miceSkeletal Muscle FibersBiochemistrymyosinsMiceMyosin headContractile Proteins0302 clinical medicineAnimal Cellsskeletal muscle fibresMyosinMedicine and Health SciencesgenderLipid HormonesPost-Translational ModificationPhosphorylationlcsh:Scienceta315Musculoskeletal SystemSex Characteristics0303 health sciencesMultidisciplinaryEstradiolRelaxation (psychology)biologyChemistryMusclesanimal experimentsEnzymesmedicine.anatomical_structurePhosphorylationFemaleCellular TypesAnatomyResearch ArticleMuscle ContractionSex characteristicsmedicine.medical_specialtyMotor ProteinssukupuolierotActin MotorseläinkokeetMuscle Fibersmyosiinitsukupuoli03 medical and health sciencesAtrophyMolecular MotorsInternal medicinemedicineAnimalslihassolut030304 developmental biology030102 biochemistry & molecular biologylcsh:RPhosphatasesBiology and Life SciencesProteinsSkeletal muscleCell BiologySkeletal Muscle Fibersmedicine.diseaseHormonesCytoskeletal Proteins030104 developmental biologyEndocrinologySkeletal MusclesageEnzymologybiology.proteinlcsh:QSteady state (chemistry)ikä030217 neurology & neurosurgery
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Response of membrane-bound ATPase of Micrococcus luteus to heat and ultraviolet light.

1976

It is shown that the properties of ATPase (EC 3.6.1.3) of Micrococcus luteus depend only to some extent on the state of the membrane to which it is attached. Its interaction with the membrane appears to be largely controlled by polar forces. It is shown, however, that the UV-sensitivity of the membrane-bound ATPase is also significantly influenced by the state of membrane lipids.

Adenosine TriphosphatasesRadiationHot TemperatureMembranesbiologyChemistryMembrane boundUltraviolet RaysMembrane lipidsATPaseBiophysicsMicrococcusDose-Response Relationship RadiationPhospholipasebiology.organism_classificationMicrococcusRadiation EffectsMembraneBiochemistryPhospholipasesUltraviolet lightbiology.proteinMicrococcus luteusGeneral Environmental ScienceRadiation and environmental biophysics
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A computational model of postprandial adipose tissue lipid metabolism derived using human arteriovenous stable isotope tracer data

2019

Given the association of disturbances in non-esterified fatty acid (NEFA) metabolism with the development of Type 2 Diabetes and Non-Alcoholic Fatty Liver Disease, computational models of glucose-insulin dynamics have been extended to account for the interplay with NEFA. In this study, we use arteriovenous measurement across the subcutaneous adipose tissue during a mixed meal challenge test to evaluate the performance and underlying assumptions of three existing models of adipose tissue metabolism and construct a new, refined model of adipose tissue metabolism. Our model introduces new terms, explicitly accounting for the conversion of glucose to glyceraldehye-3-phosphate, the postprandial …

Adipose Tissue/metabolismDIETARY FATTY-ACIDSmedicine.medical_treatmentFatty Acids NonesterifiedBiochemistry0302 clinical medicineEndocrinologyModelsInsulinGlucose/metabolismBiology (General)Organic CompoundsFatty AcidsChemical ReactionsPostprandial Period/physiologyPostprandial PeriodLipidsPostprandialBloodComputational Theory and MathematicsAdipose TissueModeling and SimulationPhysical Sciencesmedicine.medical_specialtyQH301-705.5LipolysisCarbohydratesLIPOPROTEIN-LIPASECarbohydrate metabolism03 medical and health sciencesNEFASDG 3 - Good Health and Well-beingGeneticsLipolysisHumansComputer SimulationMolecular BiologyEcology Evolution Behavior and SystematicsBlood Glucose/metabolismArteriovenous AnastomosisChemical CompoundsBiology and Life SciencesComputational BiologyComputational Biology/methodsmedicine.diseaseLipid MetabolismBiologicalHormonesLipid Metabolism/physiology030104 developmental biologyEndocrinologyBiological TissueGlucoseMOBILIZATION030217 neurology & neurosurgery0301 basic medicineGlycerolBlood GlucosePhysiologyPATHOGENESISAdipose tissueLipids/physiologySDG 3 – Goede gezondheid en welzijnVoeding Metabolisme en GenomicaGlucose MetabolismIsotopesMedicine and Health SciencesMetabolitesINSULIN-RESISTANCEEcologyChemistryHydrolysisMonomersMonosaccharidesArteriovenous Anastomosis/metabolismMetabolism and GenomicsBody FluidsChemistryFatty Acids/metabolismMetabolisme en GenomicaCarbohydrate MetabolismNutrition Metabolism and GenomicsFatty Acids Nonesterified/metabolismAnatomyResearch ArticleInsulin/metabolismINHIBITIONWEIGHT-LOSSModels BiologicalBlood PlasmaMECHANISMSCellular and Molecular NeuroscienceInsulin resistanceVoedingInternal medicinemedicineLife ScienceNonesterified/metabolismNutritionDiabetic EndocrinologyInsulinOrganic ChemistryLipid metabolismECTOPIC FATPolymer ChemistryMetabolism
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Chicken adaptive response to low energy diet: main role of the hypothalamic lipid metabolism revealed by a phenotypic and multi-tissue transcriptomic…

2019

AbstractBackgroundProduction conditions of layer chicken can vary in terms of temperature or diet energy content compared to the controlled environment where pure-bred selection is undertaken. The aim of this study was to better understand the long-term effects of a 15%-energy depleted diet on egg-production, energy homeostasis and metabolism via a multi-tissue transcriptomic analysis. Study was designed to compare effects of the nutritional intervention in two layer chicken lines divergently selected for residual feed intake.ResultsChicken adapted to the diet in terms of production by significantly increasing their feed intake and decreasing their body weight and body fat composition, whil…

Adipose tissueadaptationEnergy homeostasisTranscriptome0302 clinical medicinehypothalamusBeta oxidation2. Zero hunger0303 health sciencesprise alimentaireEndocannabinoid systemAdaptation PhysiologicalCell biologyAlimentation et NutritionBody Composition[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]BiotechnologyResearch Articlelcsh:QH426-470FADS1FADS2lcsh:BiotechnologychickenpouletBiologyModels Biological03 medical and health sciencesQuantitative Trait Heritablelipidlcsh:TP248.13-248.65GeneticsAnimalsFood and Nutritionlipide030304 developmental biologyCaloric RestrictionNeurosciencesLipid metabolismLipid MetabolismDietlcsh:GeneticsGene Expression RegulationNeurons and Cognitionfeed intakeEnergy MetabolismChickenstranscriptome;lipid;feed intake;adaptation;hypothalamus;chickentranscriptome[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition030217 neurology & neurosurgery
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Topical anti-inflammatory activity of some Asian medicinal plants used in dermatological disorders.

2001

The topical anti-inflammatory activity of extracts from Cassia angustifolia, Rheum palmatum, Coptis chinensis, Phellodendron amurense and Scutellaria baicalensis, plants used in traditional East Asian medicine against different skin disorders, was studied. Though in different degree, all the extracts significantly inhibited the edema induced by 12-O-tetradecanoylphorbol-13-acetate (TPA), in both single or multiple application, oxazolone, and arachidonic acid (AA). None of the extracts inhibited in vitro the activity of phospholipase A(2) (PLA(2)) from Naja naja.

Administration TopicalAnti-Inflammatory AgentsPharmacognosyCassia angustifoliaPhospholipases Alaw.inventionMicelawCassiaDrug DiscoveryMedicineAnimalsEdemaRosalesPharmacologyRheum palmatumPlants MedicinalTraditional medicinebiologybusiness.industryOxazoloneGeneral MedicineCoptis chinensisbiology.organism_classificationPolygonaceaePhellodendron amurenseScutellaria baicalensisFemalebusinessPhytotherapyDrugs Chinese HerbalFitoterapia
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Aneurysm clipping following endovascular coil embolization: A report of two cases

2009

Abstract BACKGROUND: Treatment of intracranial aneurysms by Guglielmi detachable coil (GDC) embolization is a useful therapeutic alternative to surgery. This procedure is attractive as a minimally invasive approach to treat cerebral aneurysms; however, is not devoid of complications or failure and retreatment, with either a surgical or endovascular technique, may often be required. CASE REPORTS: Two cases are presented in which surgery was required after coil embolization. In one case, surgical treatment was performed one month later because of regrowth and subsequent bleeding of the aneurysm. In the second case, surgical treatment was carried out six months later because of recanalization …

AdolescentSettore MED/27 - Neurochirurgiaaneurysm rest; cerebral aneurysm; guglielmi detachable coils; retreatmentIntracranial AneurysmMiddle AgedEmbolization Therapeuticcerebral aneurysmguglielmi detachable coilsCerebral aneurysm coli embolizzation subharachnoid hemorrhageCerebral aneurysm clippingHumansFemaleaneurysm restretreatment
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Los años de la hegemonía socialista. 1983-1995

2007

"Los años de la hegemonía socialista. 1983-1995" es un capítulo escrito por Benito Sanz en la obra colectiva editada por el diario Levante: "La Gran Historia de la Comunitat Valenciana. La democracia reconquistada. De la Transición a la normalización democrática (1975-2008)", tomo 10, dirigida por Francesc A. Martínez y Antonio Laguna. Valencia 2007. "Los años de la hegemonía socialista. 1983-1995" recoge las tres legislaturas en las que el PSPV-PSOE gobernó de forma hegemónica casi todas las instituciones publicas de España, la Comunidad Valenciana, así como las tres diputaciones provinciales, los tres ayuntamientos de las capitales de las provincias y la gran mayoría de los municipios. Jo…

Adolfo SuárezAltos Hornos del Mediterráneo (AHM) de Sagunto:CIENCIA POLÍTICA [UNESCO]transiciónAlfonso GuerraUNESCO::CIENCIA POLÍTICACCOO del País ValenciaPartido Socialista Obrero Español:SOCIOLOGÍA [UNESCO]Eduardo ZaplanaComunitat ValencianapantanadaRafael BlascoUNESCO::SOCIOLOGÍARicard Pérez CasadoAlianza PopularCiprià CíscarFelipe GonzálezAntonio García Miralles
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