6533b7defe1ef96bd127680c

RESEARCH PRODUCT

Topical anti-inflammatory activity of some Asian medicinal plants used in dermatological disorders.

Rosa-maría GinerJosé-luis RíosM. J. CuéllarMaría-carmen RecioSalvador Máñez

subject

Administration TopicalAnti-Inflammatory AgentsPharmacognosyCassia angustifoliaPhospholipases Alaw.inventionMicelawCassiaDrug DiscoveryMedicineAnimalsEdemaRosalesPharmacologyRheum palmatumPlants MedicinalTraditional medicinebiologybusiness.industryOxazoloneGeneral MedicineCoptis chinensisbiology.organism_classificationPolygonaceaePhellodendron amurenseScutellaria baicalensisFemalebusinessPhytotherapyDrugs Chinese Herbal

description

The topical anti-inflammatory activity of extracts from Cassia angustifolia, Rheum palmatum, Coptis chinensis, Phellodendron amurense and Scutellaria baicalensis, plants used in traditional East Asian medicine against different skin disorders, was studied. Though in different degree, all the extracts significantly inhibited the edema induced by 12-O-tetradecanoylphorbol-13-acetate (TPA), in both single or multiple application, oxazolone, and arachidonic acid (AA). None of the extracts inhibited in vitro the activity of phospholipase A(2) (PLA(2)) from Naja naja.

yearjournalcountryeditionlanguage
2001-03-01Fitoterapia
10.1016/s0367-326x(00)00305-1https://pubmed.ncbi.nlm.nih.gov/11295297