Search results for "Llanto"

showing 10 items of 29 documents

Micromechanical forces regulate vascular patterning in the chick chorioallantoic membrane (15.3)

2014

ChemistryGeneticsVascular patterningMolecular BiologyBiochemistryBiotechnologyChick chorioallantoic membraneCell biologyThe FASEB Journal
researchProduct

Ferrocenyl-Coupled N-Heterocyclic Carbene Complexes of Gold(I)

2016

Four gold(I) carbene complexes featuring 4-ferro-cenyl-substituted imidazol-2-ylidene ligands were investigated for antiproliferative and antivascular properties. They were active against a panel of seven cancer cell lines, including multidrug-resistant ones, with low micromolar or nanomolar IC50 (72 h) values, according to their lipophilicity and cellular uptake. The delocalized lipophilic cationic complexes 8 and 10 acted by increasing the reactive oxygen species in two ways: through a genuine ferrocene effect and by inhibiting the thioredoxin reductase. Both complexes gave rise to a reorganization of the F-actin cytoskeleton in endothelial and melanoma cells, associated with a G1 phase c…

StereochemistryMetallocenesThioredoxin reductaseANTITUMOR-ACTIVITYDNA-BINDINGAntineoplastic AgentsCARCINOMA-CELLSCELLULAR UPTAKEPOTENTIAL ANTICANCER010402 general chemistrymetal-based drugs01 natural sciencesCatalysisantitumor agentschemistry.chemical_compoundMiceCoordination ComplexesAnimalsQDFerrous CompoundsIC50CANCER CELLSantivascular activitychemistry.chemical_classificationTube formationReactive oxygen species010405 organic chemistryChemistryOrganic ChemistryCell migrationGeneral ChemistryIN-VITROgold0104 chemical sciencescarbenesChorioallantoic membraneLipophilicityMETAL-COMPLEXESReactive Oxygen SpeciesTHIOREDOXIN REDUCTASE INHIBITORSCHORIOALLANTOIC MEMBRANE MODELCarbeneChemistry
researchProduct

Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery …

2020

BACKGROUND: The aim of this study was to evaluate and compare the postoperative effect of a topic gel containing chlorhexidine, chitosan, allantoine and dexpanthenol versus a placebo for pain and inflammation control after third molar surgery. MATERIAL AND METHODS: A gel combining 0.2% chlorhexdine, 0.5% chitosan, 5% dexpanthenol, 0.15% allantoin and 0.01% sodium saccharin was selected for this split mouth randomized controlled and double-blind trial including 36 patients with bilaterally and symmetrically impacted lower third molars. The teeth (n=72) were randomly divided into two groups before surgical removal: control group (CG; in which a placebo was given) and experimental group (EG). …

MolarallantoinTrismusPantothenic Acidsurgerychemistry.chemical_compound0302 clinical medicineEdemaMedicinepainProspective StudiesBIOADHESIVE GELAllantoinPain PostoperativeChlorhexidinechlorhexidineTooth Impactedpostoperative wound healing:CIENCIAS MÉDICAS [UNESCO]Dry socketIThird molarAnesthesiaUNESCO::CIENCIAS MÉDICASOral Surgerymedicine.symptomDexpanthenolLife Sciences & Biomedicinemedicine.druggeldexpanthenolEXTRACTIONPlacebo03 medical and health sciencesAllantoinDouble-Blind MethodDentistry Oral Surgery & MedicineHumansGeneral DentistryInflammationChitosanScience & Technologybusiness.industryResearchINTRAALVEOLAR PLACEMENTChlorhexidine030206 dentistrymedicine.diseaseALVEOLAR OSTEITISPREVENTIONClinical trialOtorhinolaryngologychemistryTooth ExtractionMolar ThirdTrismusSurgerychitosanbusiness
researchProduct

Über den Ureidstoffwechsel beim Laubmoosprotonema von Funaria hydrometrica L. (Sibth.)1)1)Herrn Prof. Dr. Dr. Kurt Mothes zum 75. Geburtstag gewidmet.

1975

Summary The activity of allantoinase (EC 3.5.2.5) is influenced by light and darkness. The extracts of dark-grown moss protonema showed a very higher enzyme activity than the extracts of light-grown plants. The allantoinase activity was increased by light-dark and decreased by dark-light transitions. DMAP mimicked light effects by stabelizing the charakteristic light depending enzyme avctivities in the dark. The inhibitors DCMU, DNP and CCCP increased the enzyme activity of light-grown moss protonema, to some extend they induced a “physiological dark condition”.

chemistry.chemical_classificationgenetic structuresbiologyAllantoinaseDCMUGeneral MedicineGeneral Chemistrybiology.organism_classificationMossEnzyme assayFunaria hygrometricachemistry.chemical_compoundEnzymechemistryBiochemistryBotanyDarknessbiology.proteinsense organsProtonemaBiochemie und Physiologie der Pflanzen
researchProduct

Maria Magdalena dins l'univers barroc: entre el plor i l'èxtasi

2008

Una de las imágenes más características de Maria Magdalena, en los albores del Barroco, es la que la representa en la soledad de su vida retirada del mundo, con los cabellos al viento, jugando a cubrir sensual-mente su cuerpo desnudo y en el instante en que el acto de penitencia, asociado frecuentemente a su llanto, se convierte en espasmo extático. El pequeño trabajo que proponemos pretende tratar la evolución hacia esta representación del personaje, su contenido dramático generador de catarsis y construir a la vez un itinerario a través de sus identidades y de la leyenda que la ha dotado de peripecia y caracteres.

PenitenciaUNESCO::HISTORIA::Historia por especialidades::Historia del arteIconografía religiosaPintura religiosaDesnudo femeninoSantasRepresentación iconográficaCristianismoÉxtasisLlantoSensualidadIconografía femeninaPintura barroca:HISTORIA::Historia por especialidades::Historia del arte [UNESCO]
researchProduct

The effects of a topical gel containing chitosan, 0,2% chlorhexidine, allantoin and despanthenol on the wound healing process subsequent to impacted …

2016

Background Despite efforts to prevent postoperative discomfort, there are still many immediate side effects associated with the surgical extraction of impacted lower third molars. Cicatrization is a physiological process through which the loss of integrity of oral mucosa is recovered and damaged tissues are repaired. Bexident Post (ISDIN, Spain) is a topical gel that contains chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol. While this gel has many clinical indications, there are no published clinical trials evaluating its use in impacted mandibular third molar surgery. This study aims to clinically evaluate the efficacy of a gel containing chitosan, 0.2% chlorhexidine, allantoin an…

Molarmedicine.medical_specialtyDentistryMandiblelaw.invention03 medical and health scienceschemistry.chemical_compound0302 clinical medicineAllantoinRandomized controlled triallawmedicineHumansOral mucosaAllantoinGeneral DentistryChitosanPain PostoperativeWound Healingbusiness.industryResearchChlorhexidineChlorhexidineTooth ImpactedSurgical wound030206 dentistry:CIENCIAS MÉDICAS [UNESCO]Surgerymedicine.anatomical_structureOtorhinolaryngologychemistrySpain030220 oncology & carcinogenesisUNESCO::CIENCIAS MÉDICASTooth ExtractionAnti-Infective Agents LocalSurgeryMolar ThirdDexpanthenolOral SurgerybusinessWound healingmedicine.drug
researchProduct

Effects of thrombin and of the phospholipase C inhibitor, D609, on the vascularity of the chick chorioallantoic membrane.

2000

Abstract Microvascular corrosion casting was used to assess the effects of thrombin and D609, a phospholipase C inhibitor, on the vascularity of the chick embryo chorioallantoic membrane (CAM). Discs containing vehicle, thrombin or D609 were placed on the CAM of fertilized white Leghorn eggs on Day 9 of gestation and vascularity was assessed on Day 11. Thrombin caused significant increases in the numbers (43%), diameters (5%) and lengths (17%), of both pre- and postcapillaries (first-order vessels by centripetal ordering). Conversely, D609 caused a decrease in the numbers (27%), lengths (12%) and diameters (8%) of first-order vessels. D609 decreased the total vascular volume of first- to th…

Bridged-Ring Compoundsmedicine.medical_specialtyanimal structuresAngiogenesisPhosphodiesterase InhibitorsNeovascularization PhysiologicChick EmbryoBiologyHemostaticsMicrocirculationThrombinVascularityAllantoisThiocarbamatesInternal medicinemedicineAnimalsOvumPharmacologyBlood VolumePhospholipase CThrombinThionesChorionNorbornanesChorioallantoic membraneEndocrinologymedicine.anatomical_structureType C PhospholipasesCirculatory systemMicroscopy Electron Scanningmedicine.symptommedicine.drugBlood vesselGeneral pharmacology
researchProduct

COMBINATION OF ARGAN OIL AND PHOSPHOLIPIDS FOR THE DEVELOPMENT OF AN EFFECTIVE LIPOSOME-LIKE FORMULATION ABLE TO IMPROVE SKIN HYDRATION AND ALLANTOIN…

2016

Allantoin is traditionally employed in the treatment of skin ulcers and hypertrophic scars. In the present work, to improve its local deposition in the skin and deeper tissues, allantoin was incorporated in conventional liposomes and in new argan oil enriched liposomes. In both cases, obtained vesicles were unilamellar, as confirmed by cryo-TEM observation, but the addition of argan oil allowed a slight increase of the mean diameter (∼130nm versus ∼85nm). The formulations, especially those containing argan oil, favoured the allantoin accumulation in the skin, in particular in the dermis (∼8.7μg/cm(2)), and its permeation through the skin (∼33μg/cm(2)). The performances of vesicles as skin d…

3003Pig skinfood.ingredientSwineChemistry PharmaceuticalSkin AbsorptionPharmaceutical ScienceArgan oil02 engineering and technologyAdministration Cutaneous030207 dermatology & venereal diseases03 medical and health scienceschemistry.chemical_compoundDrug Delivery Systems0302 clinical medicineAllantoinfoodDermisElastic ModulusSkin rheologymedicineAnimalsPlant OilsAllantoinSofteningPhospholipidsSkinDrug CarriersLiposomeChromatographyintegumentary systemChemistryVesicleLiposomes; Argan oil; Phospholipids; Pig skin; Turbiscan lab; Skin rheology; Skin hydrationPermeation021001 nanoscience & nanotechnologyTurbiscan labmedicine.anatomical_structureSkin hydrationArgan oilLiposomesDermatologic Agents0210 nano-technologyDrug carrierargan oil; liposomes; phospholipids; pig skin; skin hydration; skin rheology; turbiscan lab; 3003
researchProduct

Plasma Metabolomics Profiles are Associated with the Amount and Source of Protein Intake: A Metabolomics Approach within the PREDIMED Study.

2020

SCOPE: The plasma metabolomics profiles of protein intake has been rarely investigated. We aimed to identify the distinct plasma metabolomics profiles associated with overall intakes of protein as well as with intakes from animal and plant protein sources. METHODS AND RESULTS: Cross-sectional analysis using data from 1,833 participants at high risk of cardiovascular disease. Plasma metabolomics analysis was performed using LC-MS. Associations between 385 identified metabolites and the intake of total, animal protein (AP) and plant protein (PP), and plant-to-animal ratio (PR) were assessed using elastic net continuous regression analyses. A double 10-cross-validation (CV) procedure was used …

0301 basic medicineMalePlasmalogenPlant Proteins DietaryArticleDimethylglycine03 medical and health scienceschemistry.chemical_compoundMetabolomicsAllantoinTrigonellineLipidomicsmedicineAnimalsHumansMetabolomicsFood scienceCarnitineAged030109 nutrition & dieteticsMiddle Aged030104 developmental biologyBloodCross-Sectional StudieschemistryDiabetes Mellitus Type 2Plant proteinCardiovascular DiseasesFemaleDietary ProteinsFood ScienceBiotechnologymedicine.drugMolecular nutritionfood research
researchProduct

Extracellular HSP27 mediates angiogenesis through Toll-like receptor 3.

2013

The heat-shock protein 27 (HSP27) is up-regulated in tumor cells and released in their microenvironment. Here, we show that extracellular HSP27 has a proangiogenic effect evidenced on chick chorioallantoic membrane. To explore this effect, we test the recombinant human protein (rhHSP27) at physiopathological doses (0.1-10 μg/ml) onto human microvascular endothelial cells (HMECs) grown as monolayers or spheroids. When added onto HMECs, rhHSP27 dose-dependently accelerates cell migration (with a peak at 5 μg/ml) and favors spheroid sprouting within 12-24 h. rhHSP27 increases VEGF gene transcription and promotes secretion of VEGF-activating VEGF receptor type 2. Increased VEGF transcription is…

Vascular Endothelial Growth Factor AImmunoprecipitationAngiogenesisHSP27 Heat-Shock ProteinsNeovascularization PhysiologicBiochemistry03 medical and health sciences0302 clinical medicineHsp27GeneticsExtracellularAnimalsSecretionReceptorMolecular BiologyCells Cultured030304 developmental biology0303 health sciencesbiologyNF-kappa BEndothelial CellsCell migrationMolecular biologyToll-Like Receptor 3Chorioallantoic membraneGene Expression Regulation030220 oncology & carcinogenesisbiology.proteinCalciumBiotechnologyFASEB journal : official publication of the Federation of American Societies for Experimental Biology
researchProduct