Search results for "Location"

Scheduling of Real-Time Networks with a Column Generation Approach

2013

We present an algorithm based on column generation for the real-time scheduling problem of allocating periodic tasks to electronic control units in multiple subsystems connected by a global bus. The allocation has to ensure that tasks can be scheduled, and messages between tasks in different subsystems can be transmitted over the global bus and meet their deadlines. Also tasks and messages occurring in a task chain must be scheduled in a way such that the sequence of execution meets their end-to-end deadline. We show that our approach computes the optimal allocation in our model and due to the column generation approach early provides lower bounds on the optimal value.

Predicting the environmental suitability for onchocerciasis in Africa as an aid to elimination planning

2021

Recent evidence suggests that, in some foci, elimination of onchocerciasis from Africa may be feasible with mass drug administration (MDA) of ivermectin. To achieve continental elimination of transmission, mapping surveys will need to be conducted across all implementation units (IUs) for which endemicity status is currently unknown. Using boosted regression tree models with optimised hyperparameter selection, we estimated environmental suitability for onchocerciasis at the 5 × 5-km resolution across Africa. In order to classify IUs that include locations that are environmentally suitable, we used receiver operating characteristic (ROC) analysis to identify an optimal threshold for suitabil…

Capecitabine and irinotecan with and without bevacizumab for advanced colorectal cancer patients

2009

AIM: To investigate the efficacy and safety of cape-citabine plus irinotecan ± bevacizumab in advanced or metastatic colorectal cancer patients. METHODS: Forty six patients with previously untreated, locally-advanced or metastatic colorectal cancer (mCRC) were recruited between 2001-2006 in a prospective open-label phase II trial, in German community-based outpatient clinics. Patients received a standard capecitabine plus irinotecan (CAPIRI) or CAPIRI plus bevacizumab (CAPIRI-BEV) regimen every 3 wk. Dose reductions were mandatory from the first cycle in cases of > grade 2 toxicity. The treatment choice of bevacizumab was at the discretion of the physician. The primary endpoints were respon…

Spontaneous regression of chronic myeloid leukemia during pregnancy.

2010

Development and Validation of a New Prognostic System for Patients with Hepatocellular Carcinoma

2016

Background Prognostic assessment in patients with hepatocellular carcinoma (HCC) remains controversial. Using the Italian Liver Cancer (ITA.LI.CA) database as a training set, we sought to develop and validate a new prognostic system for patients with HCC. Methods and Findings Prospective collected databases from Italy (training cohort, n = 3,628; internal validation cohort, n = 1,555) and Taiwan (external validation cohort, n = 2,651) were used to develop the ITA.LI.CA prognostic system. We first defined ITA.LI.CA stages (0, A, B1, B2, B3, C) using only tumor characteristics (largest tumor diameter, number of nodules, intra- and extrahepatic macroscopic vascular invasion, extrahepatic metas…

Improving uptake of screening for colorectal cancer: a study on invitation strategies and different test kit use

2015

Objective The aim of this study was to compare the uptake of mail-delivered tests for colorectal cancer screening. We assessed the effect of an advance notification letter and a reminder letter, and analysed the proportion of inappropriately handled tests. Materials and methods Fifteen thousand randomly selected residents of Latvia aged 50–74 years were allocated to receive one of three different test systems: either a guaiac faecal occult blood test (gFOBT) or one of two laboratory-based immunochemical tests (FIT) – FOB Gold or OC-Sensor. Half of the target population received an advance notification letter; all nonresponders were sent a reminder letter. Results The uptake of screening was…

Prognostic heterogeneity of adult B-cell precursor acute lymphoblastic leukaemia patients with t(1;19)(q23;p13)/TCF3-PBX1 treated with measurable res…

2021

Programa para el Tratamiento de Hemopatias Malignas (PETHEMA) Group (Spanish Society of Hematology, SEHH).

Metastatic site location may influence the diagnostic accuracy of plasma EGFR-mutation testing in NSCLC: A pooled analysis

2017

The Location of an International Logistics Center in Poland as a Part of the One Belt One Road Initiative

2019

Wstęp: Inicjatywa Jednego Pasa i Drogi otwiera wiele możliwości rozwoju dla krajów Europy Środkowo-Wschodniej. Niektóre z nich są związane z możliwością budowy centrum logistycznego w tym rejonie. Dla Polski taka inwestycja przyniosłaby wiele korzyści, nie tylko z powodu rozwoju infrastruktury, ale także z tytułu przyśpieszenia wzrostu gospodarczego i tworzenia nowych miejsc pracy. W tym kontekście kluczowa staje się rola i lokalizacja takiego centrum logistycznego. Ze względu na nowość zagadnienia, zauważa się znaczny niedobór artykułów naukowych związanych z tą kwestią. Celem naukowym niniejszego artykułu jest wypełnienie istniejącej luki, określenie roli jaką powinno spełniać polskie cen…

The location of an international logistics center in Poland as a part of The One Belt One Road Initiative

2019

Background: The One Belt One Road initiative opens up many development opportunities for Central and Eastern European countries, some related to the possible construction of a logistics center in this area. For Poland, such an investment would also bring many benefits, not only due to infrastructure development, but also through acceleration of economic growth and job creation. In this context, the crucial issue becomes, what should be the role of an international logistics center and where should it be located. Due to the novelty of the subject, there is a shortcoming of scientific papers related to this issue. The scientific goal of the present paper is to fulfill the gap and to address …