Search results for "Locator"

showing 10 items of 60 documents

Aryl hydrocarbon receptor activation by cAMP vs. dioxin: divergent signaling pathways.

2005

Even before the first vertebrates appeared on our planet, the aryl hydrocarbon receptor ( AHR ) gene was present to carry out one or more critical life functions. The vertebrate AHR then evolved to take on functions of detecting and responding to certain classes of environmental toxicants. These environmental pollutants include polycyclic aromatic hydrocarbons (e.g., benzo[ a ]pyrene), polyhalogenated hydrocarbons, dibenzofurans, and the most potent small-molecular-weight toxicant known, 2,3,7,8-tetrachlorodibenzo- p -dioxin (TCDD or dioxin). After binding of these ligands, the activated AHR translocates rapidly from the cytosol to the nucleus, where it forms a heterodimer with aryl hydroc…

Conservation of Natural ResourcesAryl hydrocarbon receptor nuclear translocatorPolychlorinated DibenzodioxinsTime FactorsTranscription GeneticGenetic VectorsGreen Fluorescent ProteinsImmunoblottingActive Transport Cell NucleusEnvironmentDioxinsLigandschemistry.chemical_compoundMiceCytosolGenes ReporterCell Line TumorCyclic AMPAnimalsImmunoprecipitationReceptorFluorescent Antibody Technique IndirectCell NucleusMultidisciplinarybiologyChemistryColforsinEndogenous mediatorrespiratory systemBiological SciencesAryl hydrocarbon receptorCyclic AMP-Dependent Protein KinasesCytosolProtein TransportBiochemistryBucladesineMicroscopy FluorescenceReceptors Aryl HydrocarbonSecond messenger systembiology.proteinProstaglandinsEnvironmental PollutantsSignal transductionDimerizationToxicantPlasmidsProtein BindingSignal TransductionProceedings of the National Academy of Sciences of the United States of America
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Coordinated Punishment and the Evolution of Cooperation

2015

In this paper, we analyze a team trust game with coordinated Q1 punishment of the allocator by investors and where there is also a final stage of peer punishment. We study the effect of punishment on the reward and the investment decisions, when the effectiveness and cost of coordinated punishment depend on the number of investors adhering to this activity. The interaction takes place in an overlapping-generations model with heterogeneous preferences and incomplete information. The only long-run outcomes of the dynamics are either a fully cooperative culture (FCC) with high levels of trust and cooperation and fair returns or a non-cooperative culture with no cooperation at all. The basin of…

Economics and EconometricsLabour economicsSociology and Political SciencePunishment (psychology)MicroeconomicsAllocatorDictator gameInvestment decisionsPeer punishmentInstitutional capacityComplete informationEconomicsPeer pressureFinanceJournal of Public Economic Theory
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Ocean acidification affects fish spawning but not paternity at CO2 seeps

2016

Fish exhibit impaired sensory function and altered behaviour at levels of ocean acidification expected to occur owing to anthropogenic carbon dioxide emissions during this century. We provide the first evidence of the effects of ocean acidification on reproductive behaviour of fish in the wild. Satellite and sneaker male ocellated wrasse (Symphodus ocellatus) compete to fertilize eggs guarded by dominant nesting males. Key mating behaviours such as dominant male courtship and nest defence did not differ between sites with ambient versus elevated CO2 concentrations. Dominant males did, however, experience significantly lower rates of pair spawning at elevated CO2 levels. Despite the higher r…

Eggs standard errorOcean Acidification International Coordination Centre (OA-ICC)TemperateRegistration number of speciesIdentificationSalinityEggsinorganicAlkalinityExperimentNumber standard errorDominant male paternityTemperature waterCarbon inorganic dissolvedNumber of individualsCalculated using seacarb after Nisumaa et al 2010Number of spawning events standard errorAragonite saturation stateFish standard lengthChordataAlkalinity totalSalinity standard errortotalCO2 ventReplicatesCourtship standard errorpHPelagosReproductionSymphodus ocellatusTemperatureNumberPartial pressure of carbon dioxide (water) at sea surface temperature (wet air) standard errordissolvedCarbonate ionPartial pressure of carbon dioxide (water) at sea surface temperature (wet air)standard errorIndividuals standard errorEarth System ResearchField observationFOS: Medical biotechnologyUniform resource locator link to referencePotentiometric titrationCalcite saturation stateLocationPotentiometricwaterNumber of spawning eventsAgeUniform resource locator/link to referenceOcean Acidification International Coordination Centre OA ICCMediterranean SeaAnimaliaEggs areaBehaviourTypeBicarbonate ionNektonEggs area standard errorTemperature water standard errorCalculated using seacarb after Nisumaa et al. (2010)SpeciespH standard errorWet massDominant male paternity standard errorCalculated using CO2SYSEvent labelIndividualsCourtshipCarbonate system computation flagstandard lengthFugacity of carbon dioxide (water) at sea surface temperature (wet air)CarbonTreatmentPartial pressure of carbon dioxide water at sea surface temperature wet airFishCarbon dioxideSingle speciesFugacity of carbon dioxide water at sea surface temperature wet airCoast and continental shelf
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A comparative assessment of the accuracy of electronic apex locator (Root ZX) in the presence of commonly used irrigating solutions

2013

Objectives: This study aimed to evaluate the accuracy of Root ZX in determining working length in presence of normal saline, 0.2% chlorhexidine and 2.5% of sodium hypochlorite. Material and Methods: Sixty extracted, single rooted, single canal human teeth were used. Teeth were decoronated at CEJ and actual canal length determined. Then working length measurements were obtained with Root ZX in presence of normal saline 0.9%, 0.2% chlorhexidine and 2.5% NaOCl. The working length obtained with Root ZX were compared with actual canal length and subjected to statistical analysis. Results: No statistical significant difference was found between actual canal length and Root ZX measurements in pres…

Electronic apex locatorbusiness.industryResearchmedicine.medical_treatmentSignificant differenceChlorhexidineStatistical differenceDentistryOdontología:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludThird generationchemistry.chemical_compoundchemistrySodium hypochloriteUNESCO::CIENCIAS MÉDICASmedicineIRRIGATING SOLUTIONSNew technologies in DentistrybusinessGeneral DentistrySalinemedicine.drugJournal of Clinical and Experimental Dentistry
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First pollen-based REVEALS reconstruction of vegetation abundance in Europe for five time windows between 6k years BP and present

2019

The submitted dataset includes the pollen-based REVEALS estimates of 11 plant functional types (PFTs) and 3 land-cover types (LCTs) for Europe, published in Trondman et al. (2015) as part of the results from the Swedish project LandClim I (Gaillard et al., 2010). In this project, pollen-based REVEALS estimates of land cover for 5 time windows of the Holocene were used to evaluate the scenarios of anthropogenic land-cover change (ALCC) KK and HYDE (Kaplan et al., 2017) and to study the biogeophysical forcing of ALCC between the time windows 6200-5700 years BP and CE 1600-1850 (Strandberg et al., 2014). The reconstruction is based on 25 pollen taxa for which pollen productivity of the corresp…

File nameFile sizeUniform resource locator link to fileFile contentUniform resource locator/link to fileEarth System ResearchFile format
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Raster maps for 29 environmental variables in three geographical regions

2015

Aim: Greater understanding of the processes underlying biological invasions is required to determine and predict invasion risk. Two subspecies of olive (Olea europaea subsp. europaea and Olea europaea subsp. cuspidata) have been introduced into Australia from the Mediterranean Basin and southern Africa during the 19th century. Our aim was to determine to what extent the native environmental niches of these two olive subspecies explain the current spatial segregation of the subspecies in their non-native range. We also assessed whether niche shifts had occurred in the non-native range, and examined whether invasion was associated with increased or decreased occupancy of niche space in the no…

File nameFile sizeUniform resource locator link to fileUniform resource locator/link to fileEarth System Research
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Isomer-nonspecific action of dichlorodiphenyltrichloroethane on aryl hydrocarbon receptor and G-protein-coupled receptor 30 intracellular signaling i…

2014

Abstract Extended residual persistence of the pesticide dichlorodiphenyltrichloroethane (DDT) raises concerns about its long-term neurotoxic effects. Little is known, however, about DDT toxicity during the early stages of neural development. This study demonstrated that DDT-induced apoptosis of mouse embryonic neuronal cells is a caspase-9-, caspase-3-, and GSK-3β-dependent process, which involves p,p’ -DDT-specific impairment of classical ERs. It also provided evidence for DDT-isomer-nonspecific alterations of AhR- and GPR30-mediated intracellular signaling, including changes in the levels of the receptor and receptor-regulated mRNAs, and also changes in the protein levels of the receptors…

GPR30Time FactorsGSK-3 betaEstrogen receptorApoptosisStimulationBiochemistryReceptors G-Protein-CoupledGlycogen Synthase Kinase 3MiceEndocrinologyneurotoxicityestrogenReceptorCells CulturedNeuronsbiologyCaspase 3estrogen receptorsCaspase InhibitorsCell biologycaspasesReceptors EstrogenQuinolinesGPERNeural developmentSignal Transductionmedicine.medical_specialtyAryl hydrocarbon receptor nuclear translocatorneuronal cell culturesDDT17-beta-estradiolIsomerismbeta-NaphthoflavoneInternal medicineparasitic diseasesCytochrome P-450 CYP1A1medicineAnimalsBcl-2BenzodioxolesRNA MessengerMolecular BiologyG protein-coupled receptorBenzoflavonesGlycogen Synthase Kinase 3 betaL-Lactate DehydrogenaseAryl hydrocarbon receptorPyrimidinesEndocrinologyReceptors Aryl Hydrocarbonbiology.proteinPyrazolesMolecular and Cellular Endocrinology
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Growth rates of F0 and F1 larval and juvenile European seabass Dicentrarchus labrax in resonse to ocean acidification and warming

2022

Ongoing climate change is leading to warmer and more acidic oceans. The future distribution of fish within the oceans depends on their capacity to adapt to these new environments. Only few studies have examined the effects of ocean acidification (OA) and warming (OW) on the metabolism of long-lived fish over successive generations. We therefore aimed to investigate the effect of OA on larval and juvenile growth and metabolism on two successive generations of European sea bass (Dicentrarchus labrax L.) as well as the effect of OAW on larval and juvenile growth and metabolism of the second generation. European sea bass is a large economically important fish species with a long generation time…

GenerationTank numberLife stagedry massType of studyocean warmingjuvenile growthAgeUniform resource locator/link to referenceWeightedDATE TIMEDicentrarchus labraxTreatment temperatureSpeciesbody lengthlarval growthteleostCaliperOcean acidificationTreatment partial pressure of carbon dioxideLaboratory experimentTreatment: temperatureDATE/TIMESample IDTreatment: partial pressure of carbon dioxideDicentrarchus labrax body lengthEarth System Researchmassmetabolic ratesUniform resource locator link to referenceDicentrarchus labrax dry massDicentrarchus labrax mass
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Deletion of myosin VI causes slow retinal optic neuropathy and age-related macular degeneration (AMD)-relevant retinal phenotype

2015

The unconventional myosin VI, a member of the actin-based motor protein family of myosins, is expressed in the retina. Its deletion was previously shown to reduce amplitudes of the a- and b-waves of the electroretinogram. Analyzing wild-type and myosin VI-deficient Snell’s Waltzer mice in more detail, the expression pattern of myosin VI in retinal pigment epithelium, outer limiting membrane, and outer plexiform layer could be linked with differential progressing ocular deficits. These encompassed reduced a-waves and b-waves and disturbed oscillatory potentials in the electroretinogram, photoreceptor cell death, retinal microglia infiltration, and formation of basal laminar deposits. A pheno…

Genotypegenetic structuresOuter retinaTranslocator protein TSPOOuter plexiform layermacromolecular substancesBiologyRetinaPhotoreceptor cellMouse modelStereociliaMacular DegenerationMiceCellular and Molecular Neurosciencechemistry.chemical_compoundOptic Nerve DiseasesMyosinmedicineAnimalsBipolar cellMolecular BiologyPharmacologyRetinaRetinal pigment epitheliumMyosin Heavy ChainsNeurodegenerationInner retinaChoriocapillarisRetinalCell BiologyAnatomyMacular degenerationmedicine.diseaseSynapseeye diseasesCell biologyMice Inbred C57BLmedicine.anatomical_structurechemistryMolecular MedicineMicrogliasense organsGene DeletionResearch ArticlePhotoreceptor Cells VertebrateCellular and Molecular Life Sciences
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Global distributions of diazotrophs abundance and biomass - Depth integrated values computed from a collection of source datasets - Contribution to t…

2013

The MAREDAT atlas covers 11 types of plankton, ranging in size from bacteria to jellyfish. Together, these plankton groups determine the health and productivity of the global ocean and play a vital role in the global carbon cycle. Working within a uniform and consistent spatial and depth grid (map) of the global ocean, the researchers compiled thousands and tens of thousands of data points to identify regions of plankton abundance and scarcity as well as areas of data abundance and scarcity. At many of the grid points, the MAREDAT team accomplished the difficult conversion from abundance (numbers of organisms) to biomass (carbon mass of organisms). The MAREDAT atlas provides an unprecedente…

Go-Flo bottlesSalinityCAIBEX-IRV Kilo MoanaDiazotrophs total biomass as carbonUniform resource locator link to source data fileNitrateRichelia carbon per cellCTD/RosetteLatitude of eventNiskinRoger A RevelleTemperature waterCalculatedtop minbiomass as carbonTrichodesmium biomass as carbontotalbottom maxCTD Seabirdareal concentrationMultiple investigationsTemperatureDepth top/minRichelia abundance cellsCTD RosetteSeabirdCalothrixRoger A. RevelleTrichodesmiumTrichodesmium carbon per trichomeEarth System ResearchRichelia abundanceCAIBEX-IICalothrix abundanceMARine Ecosystem Model Intercomparison Project MAREMIPDiazotrophsLongitude of eventRichelia associated speciesSample methodIronChlorophyll total areal concentrationBottle NiskinwaterTrichodesmium abundance free trichomesMARine Ecosystem Model Intercomparison Project (MAREMIP)PhosphateSarmiento de GamboaSample commentCAIBOXUniform resource locator/link to source data filetotal biomass as carbonCalothrix carbon per cellHeterocyst biomassGo Flo bottlescoloniesDate/Time of eventChlorophyll totalTrichodesmium abundance totalRicheliaDEPTH waterTrichodesmium abundance coloniesMP-6biomassBottleDepthEvent labelDate Time of eventCAIBEX IIcarbon per cellMeasured at sea surfacefree trichomesMP-9CTDCalothrix abundance cellscarbon per trichomeTrichodesmium abundanceCalothrix associated speciesMP 9MP 6CAIBEX IcellsDepth bottom/maxassociated speciesHeterocyst
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