Search results for "M3"
showing 10 items of 175 documents
Activation of Muscarinic Receptors by Non-neuronal Acetylcholine
2011
The biological role of acetylcholine and the cholinergic system is revisited based particularly on scientific research early and late in the last century. On the one hand, acetylcholine represents the classical neurotransmitter, whereas on the other hand, acetylcholine and the pivotal components of the cholinergic system (high-affinity choline uptake, choline acetyltransferase and its end product acetylcholine, muscarinic and nicotinic receptors and esterase) are expressed by more or less all mammalian cells, i.e. by the majority of cells not innervated by neurons at all. Moreover, it has been demonstrated that acetylcholine and “cholinergic receptors” are expressed in non-neuronal organism…
Constraining the invisible neutrino decay with KM3NeT-ORCA
2019
Several theories of particle physics beyond the Standard Model consider that neutrinos can decay. In this work we assume that the standard mechanism of neutrino oscillations is altered by the decay of the heaviest neutrino mass state into a sterile neutrino and, depending on the model, a scalar or a Majoron. We study the sensitivity of the forthcoming KM3NeT-ORCA experiment to this scenario and find that it could improve the current bounds coming from oscillation experiments, where three-neutrino oscillations have been considered, by roughly two orders of magnitude. We also study how the presence of this neutrino decay can affect the determination of the atmospheric oscillation parameters $…
A Case Study on the Implementation of Stakeholder Management in Organizational Practice
2017
Recent research makes a strong argument for studying how organizations can implement a strategic stakeholder management approach. In this paper, we analyze an empirical case study in order to gain refined knowledge and develop ‘best’ implementation tactics, building on Plaza-Ubeda et al., (A case study of stakeholder identification and prioritization by managers, Journal of Business Ethics, 75: 1–23, 2010) conceptualization of the implementation of stakeholder integration (SI). The case study draws on a project concerning our own university, a private higher-education provider, which faces a new regulatory environment. In response to new legal measures, which include accounting for stakehol…
Inside service-intensive projects: Analyzing inbuilt tensions
2015
The purpose of this research is to identify typical professional and occupational groups in service-intensive projects, and illustrate the inbuilt tensions among them through the lens of institutional theory. The cases used for the study are a wind turbine business and a content management system project business. Our findings suggest that there are two professional groups (problem solvers, technology developers) and two occupational groups (lead generators, relationship developers) involved in these businesses. More importantly, their intergroup tensions are related to different institutionalized logics toward the conception of time (project temporality) and prioritization of different asp…
Expansion cone for the 3-inch PMTs of the KM3NeT optical modules
2013
[EN] Detection of high-energy neutrinos from distant astrophysical sources will open a new window on the Universe. The detection principle exploits the measurement of Cherenkov light emitted by charged particles resulting from neutrino interactions in the matter containing the telescope. A novel multi-PMT digital optical module (DOM) was developed to contain 31 3-inch photomultiplier tubes (PMTs). In order to maximize the detector sensitivity, each PMT will be surrounded by an expansion cone which collects photons that would otherwise miss the photocathode. Results for various angles of incidence with respect to the PMT surface indicate an increase in collection efficiency by 30% on average…
ANTARES: The first undersea neutrino telescope
2011
The ANTARES Neutrino Telescope was completed in May 2008 and is the first operational Neutrino Telescope in the Mediterranean Sea. The main purpose of the detector is to perform neutrino astronomy and the apparatus also offers facilities for marine and Earth sciences. This paper describes the design, the construction and the installation of the telescope in the deep sea, offshore from Toulon in France. An illustration of the detector performance is given. © 2011 Elsevier B.V. All rights reserved.
How does the online service level influence consumers’ purchase intentions before a transaction? A formative approach
2016
AbstractThe present paper tries to study the impact of online services level in contexts where transactions have not been done yet, through the adoption of a formative approach. In this scene, the present research considers two main dimensions of online services (pre-purchase services and transaction-related services) in a context of clothing purchasing process. Before defining the research and determining the sector to be analyzed, 7 focus groups were conducted. From the obtained conclusions, this study was carried on in the textile sector. A survey with 370 effective respondents was carried out. To measure the different concepts in the model, several scales were used based on literature p…
The combined use of quality management programs and work teams
2006
PurposeThe main goal of the work presented here is the study and comparative analysis of the changes that take place in the structure of organizations when managers decide to establish work teams in the context of quality management. It can be observed that team characteristics change and adapt to evolving management programs.Design/methodology/approachThe authors selected a qualitative research method, in particular the case study methodology. The comparative analysis of organizational changes was analyzed in three different business units that had implanted advanced quality management programs using work teams.FindingsThere is a relationship between the quality management approach and the…
La elección de la marca del distribuidor en productos duraderos: factores de influencia
2010
[ES] La apuesta de la distribución por la extensión de su marca a las categorías de productos duraderos, como electrodomésticos y productos electrónicos para el hogar, ha demostrado ser acertada, a pesar de las críticas en contra de esta estrategia. Posiblemente, la mayor familiaridad del consumidor con las marcas del distribuidor, el cambio de actitud favorable hacia éstas, la disponibilidad de la tecnología, y por qué no, la crisis económica internacional que afecta a las economías domésticas, pueden ser factores explicativos de este éxito. El escaso número de trabajos que tratan de explicar las razones de aceptación de estas marcas en productos duraderos nos ha llevado a plantear si las …
Causas y consecuencias de la insatisfacción en consumidores con atribuciones externas
2011
[ES] Este trabajo aborda el estudio de la formación de la insatisfacción, desde la perspectiva cognitiva y afectiva, y de sus consecuencias en forma de intenciones de comportamientos de queja. El objetivo es investigar la influencia directa e indirecta, a través de los afectos negativos, que ejerce la desconfirmación de expectativas sobre la insatisfacción, y analizar la contribución de estos juicios sobre las intenciones de respuestas de queja, a terceras partes y privadas. A partir de una muestra de clientes insatisfechos con restaurantes que manifiestan distintos niveles de atribución externa, se ha construido un modelo causal para estudiar las relaciones. Los resultados confirman la exi…