Search results for "MAI"

showing 10 items of 6279 documents

Neuroethics 1995-2012. A bibliometric analysis of the guiding themes of an emerging research field

2016

International audience; In bioethics, the first decade of the twenty-first century was characterized by the emergence of interest in the ethical, legal and social aspects of neuroscience research. At the same time an ongoing extension of the topics and phenomena addressed by neuroscientists was observed alongside its rise as one of the leading disciplines in the biomedical science. One of these phenomena addressed by neuroscientists and moral psychologists was the neural processes involved in moral decision-making. Today both strands of research are often addressed under the label of neuroethics. To understand this development we recalled literature from 1995 to 2012 stored in the Mainz Neu…

Bibliometric analysis0603 philosophy ethics and religionscientometricsneuroethics03 medical and health sciencesBehavioral Neuroscience0302 clinical medicine[SHS.ECO] Humanities and Social Sciences/Economics and FinanceBiological PsychiatryOriginal ResearchField (Bourdieu)bibliography06 humanities and the artsBioethicsScientometricsscience studies[SHS.ECO]Humanities and Social Sciences/Economics and FinancePsychiatry and Mental healthNeuropsychology and Physiological PsychologyNeurologyMainz Neuroethics Databasehistory of neuroethics[SHS.GESTION]Humanities and Social Sciences/Business administrationEngineering ethics060301 applied ethicsNeuroscience researchScience studiesPsychologyNeuroethics[SHS.GESTION] Humanities and Social Sciences/Business administrationNeuroscience030217 neurology & neurosurgeryNeuroscience
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Latvijas Universitātes Bibliotēkas sadarbības iespējas gadsimta griezumā (1919-2019)

2020

Latvijas Universitātes 78. zinātniskās konferences Bibliotēkzinātnes un informācijas zinātnes sekcijas sēdes ietvaros sniegts ieskats LU Bibliotēkas vēsturē no tās dibināšanas brīža līdz par šodienai. Ziņojuma tēma veltīta LU Bibliotēkas sadarbības iespēju izpētei laika posmā no 1919. līdz 2019. gadam. Tajā aplūkoti divi LU Bibliotēkas sadarbības aspekti: grāmatu apmaiņas process krājuma komplektēšanas nolūkā un bibliotēkas darbinieku kvalifikācijas paaugstināšana, ietverot pieredzes apmaiņas vizītes padomju periodā līdz pat mūsdienām. Izpētes gaitā izmantoti nepublicēti materiāli : LU Bibliotēkas dokumentu kopa no 1983. līdz 1999. gadam un LU Bibliotēkas atskaites Latvijas valsts arhīvā pa…

Bibliotēkas sadarbībaLatvijas Universitātes Bibliotēka - vēstureBibliotēkas darbinieku kvalifikācijas paaugstināšanaGrāmatu apmaiņa:SOCIAL SCIENCES::Other social sciences::Library and information science [Research Subject Categories]
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Mirklis 100 gadi: Latvijas Universitātes Bibliotēka 1919 -2019 : izstādes plakāti

2019

LU Bibliotēkas veidotā stendu izstāde “Mirklis 100 gadi: Latvijas Universitātes Bibliotēka 1919 -2019” ir veltīta Latvijas Universitātes 100. gadadienai un ir pēdējā izstāžu sērijā. Lai gan Latvijas Universitātes Bibliotēkas pirmsākumi ir atrodami jau 1862. gadā, kad dibināts Rīgas Politehnikums un Bibliotēka, izstādē sniegts ieskats LU Bibliotēkas attīstībā no Latvijas Augstskolas dibināšanas un Centrālās Bibliotēkas veidošanas 1919. gadā līdz 2019. gadam. Izstādē atspoguļota Bibliotēkas un fakultāšu bibliotēku attīstība, to atrašanās vietas, raksturoti tās vadītāji, kā arī ikdienas darbā izmantotās tehnoloģijas, gadu gaitā paveiktais bibliotekāro darba procesu un pakalpojumu pilnveidošanā…

Bibliotēkas sadarbībaLatvijas Universitātes Bibliotēka - vēstureSērija "Mirkļu izstāde"Bibliotēkas struktūras izmaiņaBibliotēkas atrašanās vietas maiņaBibliotekārā darba palīglīdzekļiBibliotēkas vadītāji/direktoriBibliotēkas publikācijas un biobibliogrāfijas:SOCIAL SCIENCES [Research Subject Categories]Bibliotēkas automatizācija
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2013

Currently, a growing number of programs become available in statistical software for multiple imputation of missing values. Among others, two algorithms are mainly implemented: Expectation Maximization (EM) and Multiple Imputation by Chained Equations (MICE). They have been shown to work well in large samples or when only small proportions of missing data are to be imputed. However, some researchers have begun to impute large proportions of missing data or to apply the method to small samples. A simulation was performed using MICE on datasets with 50, 100 or 200 cases and four or eleven variables. A varying proportion of data (3% - 63%) was set as missing completely at random and subsequent…

Binary responseSample size determinationStatisticsExpectation–maximization algorithmEconometricsMain effectImputation (statistics)Missing dataInteractionLogistic regressionMathematicsOpen Journal of Statistics
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Specific Zn(II)-binding site in the C-terminus of Aspf2, a zincophore from Aspergillus fumigatus

2022

Abstract Aspergillus fumigatus, one of the most widespread opportunistic human fungal pathogens, adapts to zinc limitation by secreting a 310 amino acid Aspf2 zincophore, able to specifically bind Zn(II) and deliver it to a transmembrane zinc transporter, ZrfC. In this work, we focus on the thermodynamics of Zn(II) complexes with unstructured regions of Aspf2; basing on a variety of spectrometric and potentiometric data, we show that the C-terminal part has the highest Zn(II)-binding affinity among the potential binding sites, and Ni(II) does not compete with Zn(II) binding to this region. The 14 amino acid Aspf2 C-terminus coordinates Zn(II) via two Cys thiolates and two His imidazoles and…

Binding SitesAspergillus fumigatusZn(II)- and Ni(II)-binding peptidesMetals and AlloysBiophysicsBiochemistryBiomaterialsZincthermodynamicsProtein DomainsChemistry (miscellaneous)zincophorepotentiometryHumansAmino AcidsMetallomics
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In vivo detection, RNA-binding properties and characterization of the RNA-binding domain of the p7 putative movement protein from carnation mottle ca…

1999

Biochemical and structural characterization studies on the p7 putative movement protein from a Spanish isolate of carnation mottle carmovirus (CarMV) have been conducted. The CarMV p7 gene was fused to a sequence coding for a six-histidine tag and expressed in bacteria, allowing the purification of CarMV p7 and the production of a specific antiserum. This antiserum led to the immunological identification of CarMV p7 in infected leaf tissue from the experimental host Chenopodium quinoa. Putative nucleic acid-binding properties of the CarMV p7 have been explored and demonstrated with both electrophoretic mobility shift and RNA-protein blot in vitro assays using digoxigenin-labeled riboprobes.…

Binding SitesCarmovirusRecombinant Fusion ProteinsMolecular Sequence DataCooperative bindingRNARNA-Binding ProteinsBiologybiology.organism_classificationMolecular biologyPlant Viral Movement ProteinsViral ProteinsBiochemistryVirologyNucleic acidEscherichia coliCarmovirusAmino Acid SequenceMovement proteinPeptide sequenceGeneBinding domainVirology
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Exponential Relaxation out of Nonequilibrium

1989

Simulation results are presented for a quench from a disordered state to a state below the coexistence curve. The model which we consider is the Ising model but with the dynamics governed by the Swendsen-Wang transition probabilities. We show that the resulting domain growth has an exponential instead of a power law behaviour and that the system is non-self-averaging while in nonequilibrium. The simulations were carried out on a parallel computer with up to 128 processors.

BinodalPhysicsCondensed Matter::Statistical MechanicsGeneral Physics and AstronomyRelaxation (physics)Non-equilibrium thermodynamicsIsing modelStatistical physicsState (functional analysis)Power lawDomain (mathematical analysis)Exponential functionEurophysics Letters (EPL)
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Metodes viena un vairāku maiņas punktu atrašanai laikrindu datiem

2019

Maiņas punkti ir pēkšņas izmaiņas laikrindu datos. Maiņas punktu analīze ir būtiska laikrindu modelēšanā un prognozēšanā. Tā ir svarīga tādās nozarēs kā medicīna, vides zinātne, ekonomika u.c. Darba mērķis ir iepazīties ar maiņas punktu meklēšanas metodēm, pārbaudītšīsmetodesgansimulētiemdatiem,ganreāliemlaikrindupiemēriem.Darbateorētiskajādaļātiekaprakstītamaiņaspunktuproblemātikaganvienamaiņaspunktagadījumā, gan vairāku maiņas punktu gadījumā. Teorētiskajā daļā tiek apskatītas tādas viena maiņas punkta meklēšanas metodes kā CUSUM un robusta maiņas punkta meklēšanas metode, kas balstīta uz divu izlašu Hodža- Lēmaņa novērtējumu. Teorētiskajā daļā tiek apskatītas tādas vairāku maiņas punkta …

Binārās segmentācijas algoritmsPELTCUSUMMatemātikaRobusta maiņas punktu atrašanas metodeMaiņas punkts
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Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

2015

Cells exposed to extreme physicochemical or mechanical stimuli die in an uncontrollable manner, as a result of their immediate structural breakdown. Such an unavoidable variant of cellular demise is generally referred to as ?accidental cell death' (ACD). In most settings, however, cell death is initiated by a genetically encoded apparatus, correlating with the fact that its course can be altered by pharmacologic or genetic interventions. "Regulated cell death" (RCD) can occur as part of physiologic programs or can be activated once adaptive responses to perturbations of the extracellular or intracellular microenvironment fail. The biochemical phenomena that accompany RCD may be harnessed to…

Biochemical Manifestations of Cell DeathISCHEMIA-REPERFUSION INJURYApoptosisReviewTransduction (genetics)0302 clinical medicineCASPASE INHIBITION SWITCHESAnimals; Humans; Terminology as Topic; Apoptosis; Signal Transduction610 Medicine & healthCaspaseTUMOR-NECROSIS-FACTOR0303 health sciencesSettore BIO/17biologySettore BIO/11NeurodegenerationSettore BIO/13APOPTOSIS3. Good healthMedicina Básicacell death030220 oncology & carcinogenesiscell death; Morphologic Aspects of Cell Death; Biochemical Manifestations of Cell DeathSignal transductionDOMAIN-LIKE PROTEINIntracellularHumanSignal TransductionNecroptosiCYTOCHROME-C RELEASEOUTER-MEMBRANE PERMEABILIZATIONProgrammed cell deathCIENCIAS MÉDICAS Y DE LA SALUDSettore BIO/06Inmunología610 Medicine & healthCELL DEATHNOQ-VD-OPH03 medical and health sciencesSettore MED/04 - PATOLOGIA GENERALEddc:570Terminology as TopicAPOPTOSIS-INDUCING FACTORMIXED LINEAGE KINASEmedicineAnimalsHumansAnimals; Humans; Terminology as Topic; Apoptosis; Signal Transduction; Molecular Biology; Cell BiologyMorphologic Aspects of Cell DeathSettore BIO/10Molecular Biology030304 developmental biologyAnimalCell growthApoptosiBiology and Life SciencesCell Biologymedicine.diseaseMITOCHONDRIAL PERMEABILITY TRANSITIONApoptosisImmunologybiology.proteinNeuroscienceCell death and differentiation
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Kopīgo resursu pārvaldība krīžu saplūšanas laikā

2022

Kolektīvā monogrāfija “Kopīgo resursu pārvaldība krīžu saplūšanas laikā” apkopo galvenās pētnieciskā projekta “Gatavi pārmaiņām? Kopīgo dabas resursu ilgtspējīga pārvaldība” (LZP-2019/1-0319) (projekta vadītājs LU SZF SPPI vadošais pētnieks Jurijs Ņikišins) atziņas.

Bioloģiskā lauksaimniecība - LatvijaKlimata pārmaiņasEkosistēmas izturētspējaDabas resursu menedžmentsMežsaimniecība - LatvijaGadījumu analīze:NATURAL SCIENCES [Research Subject Categories]
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