Search results for "MAb"

showing 10 items of 1716 documents

Design of a mezzanine card with bandwidth aggregation for HPGe gamma spectroscopy

2016

In experimental nuclear physics, HPGe segmented detectors are used to provide high energy resolution of the gamma rays. Besides, 4pi configuration is common to get a full coverage of the interaction point and detection of all the products of the collisions. In this type of experiments, the number of electronic channels can be high (>100) and also the sampling frequency of the digitizing system (>100 Msps). This results in a high data rate per channel (> 2 Gbps) and thus a high aggregated bandwidth to process. In principle, this problem can be solved using a parallel data acquisition system where the input channels (commonly arriving through optical fibers) are read and processed accordingly…

Engineeringbusiness.product_categoryData acquisitionbusiness.industryBandwidth (signal processing)Electronic engineeringNetwork switchElectronicsTransceiverbusinessField-programmable gate arrayMultiplexingCommunication channel2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD)
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Using the Microcontroller and the PLC in a RPP Robot Control

2012

This paper presents some aspects regarding the possibility of combining microcontroller and programmable logic controller (PLC) for robot control. The RPP robot is designed and manufactured within the Faculty of Engineering from “Lucian Blaga” University of Sibiu, as a patent: BRAŢ TELESCOPIC, Nr. 112418 B1, Int.CI.6 B 25 J 18/02, from 17.02.1997. Classical systems for programming and control of industrial robot are based on numerical control equipment, developed around a PC. Programmable Logic Controllers (PLC) haves proven to be viable alternatives to driving machine tools, industrial systems and Robots. Microcontrollers as computers offer advantage due to programmable inputs and outputs …

Engineeringbusiness.product_categorybusiness.industrySimatic S5 PLCGeneral EngineeringProgrammable logic controllerControl engineeringlaw.inventionMachine toolRobot controlIndustrial robotMicrocontrollerlawNumerical controlRobotbusinessComputer hardwareAdvanced Materials Research
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Warehouse threats and loss prevention management in case of fire

2016

Abstract Warehouses play an important role when it comes to the reception, delivery and storage of various types of goods. Due to the complex scenarios that may occur, as well as the heterogeneous nature of goods, warehouses bear a higher risk of accidents. Regardless if we’re taking about removing hassle or standardizing operations we speak the same language: insuring efficiency and increased efficiency leads to smart cost maintenances. In the article hear by we will observe the behavior of different warehouse materials in the case of trigger fired. Starting from the results obtained during the low scale tests and completing the premises with the large scale experiment (warehouse scale), w…

Engineeringflammable substances.business.industryScale (chemistry)010401 analytical chemistry0211 other engineering and technologieshealth and safety at work02 engineering and technologyComputer securitycomputer.software_genre01 natural sciences0104 chemical sciencesWarehouseRisk analysis (engineering)021105 building & constructionfire protectionGeneral Earth and Planetary Scienceswarehouseflammable substancesbusinessOSH culture fire fire protection warehousehealth and safety at work flammable substancescomputerfireGeneral Environmental ScienceOSH culture
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Exploring FPGA‐Based Lock‐In Techniques for Brain  Monitoring Applications

2017

Functional near‐infrared spectroscopy (fNIRS) systems for e‐health applications usually suffer from poor signal detection, mainly due to a low end‐to‐end signal‐to‐noise ratio of the electronics chain. Lock‐in amplifiers (LIA) historically represent a powerful technique helping to improve performance in such circumstances. In this work a digital LIA system, based on a Zynq® field programmable gate array (FPGA) has been designed and implemented, in an attempt to explore if this technique might improve fNIRS system performance. More broadly, FPGA‐based solution flexibility has been investigated, with particular emphasis applied to digital filter parameters, needed in the digital LIA, and its …

Engineeringhardware description language (HDL) near‐infrared  spectroscopy (NIRS)light emitting diode (LED)Computer Networks and Communicationslcsh:TK7800-836002 engineering and technologysilicon photomultiplier (SiPM)Settore ING-INF/01 - Elettronica01 natural sciencesSignaldigital lock‐in amplifier (DLIA)law.invention hardware description language (HDL)microprocessorslawVHDL0202 electrical engineering electronic engineering information engineeringElectronic engineeringDetection theoryElectrical and Electronic EngineeringField-programmable gate arraycomputer.programming_languagebusiness.industryNoise (signal processing)lcsh:Electronics010401 analytical chemistryEmphasis (telecommunications)near‐infrared spectroscopy (NIRS)020206 networking & telecommunications0104 chemical sciences light emitting diode (LED) microprocessorsfield programmable gate array (FPGA)Microprocessordigital lock‐in amplifier (DLIA)Hardware and ArchitectureControl and Systems EngineeringSignal Processingbusinessdigital lock‐in amplifier (DLIA); field programmable gate array (FPGA); near‐infrared  spectroscopy (NIRS); hardware description language (HDL); light emitting diode (LED); silicon  photomultiplier (SiPM); microprocessors field programmable gate array (FPGA) silicon  photomultiplier (SiPM)Digital filtercomputerComputer hardwareElectronics
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Towards ductilization of high strength 7XXX aluminium alloys via microstructural modifications obtained by friction stir processing and heat treatmen…

2021

Abstract High strength 7XXX aluminium series reach exceptional strength, higher than all other industrial aluminium alloys. However, they suffer from a lack of ductility compared to softer series. This work presents a procedure to improve the ductility of 7475 Al alloy in high strength condition, reaching a true fracture strain of 70% at full 500 MPa T6 yield strength. Using friction stir processing (FSP) and post-FSP heat treatments, 100% of industrial rolled material T6 yield stress is maintained but a 180% increase in fracture strain is measured for the processed material. This ductility improvement is studied by in-situ synchrotron X-ray tomography and is explained by the reduction of i…

Equiaxed crystalsFriction stir processingMaterials scienceAlloyIntermetallicchemistry.chemical_element02 engineering and technologyengineering.material030226 pharmacology & pharmacy[SPI.MAT]Engineering Sciences [physics]/Materials03 medical and health sciences0302 clinical medicineAluminiumFormabilityGeneral Materials ScienceComposite materialDuctilityMicrostructureCrack propagationPhysicsDuctilizationAluminium alloysFriction stir processing (FSP)021001 nanoscience & nanotechnologyMicrostructurechemistryengineering0210 nano-technology
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Marine Anticancer Agents: An Overview with a Particular Focus on Their Chemical Classes

2020

The marine environment is a rich source of biologically active molecules for the treatment of human diseases, especially cancer. The adaptation to unique environmental conditions led marine organisms to evolve di erent pathways than their terrestrial counterparts, thus producing unique chemicals with a broad diversity and complexity. So far, more than 36,000 compounds have been isolated from marine micro- and macro-organisms including but not limited to fungi, bacteria, microalgae, macroalgae, sponges, corals, mollusks and tunicates, with hundreds of new marine natural products (MNPs) being discovered every year.Marine-based pharmaceuticals have started to impactmodern pharmacology and diff…

Eribulin MesylateAquatic OrganismsEnfortumab vedotinLurbinectedinPharmaceutical ScienceAntineoplastic AgentsMarine drugsComputational biologyReviewBiology03 medical and health scienceschemistry.chemical_compound0302 clinical medicineSDG 3 - Good Health and Well-beingNeoplasmsmedicineAnimalsHumansSDG 14 - Life Below WaterBrentuximab vedotinlcsh:QH301-705.5Pharmacology Toxicology and Pharmaceutics (miscellaneous)030304 developmental biologyFludarabine Phosphate0303 health sciencesBiological ProductsDrug discoveryDrug discoveryClinical pipelinePolatuzumab vedotinAnticancerlcsh:Biology (General)chemistry030220 oncology & carcinogenesisMarine natural productsMarine ToxinsPlitidepsinWater Microbiologymedicine.drug
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Rheological blood behaviour is not related to gender in morbidly obese subjects.

2012

To the Editor. We have read with interest the recently published article by Wiewiora et al. [7] regarding hemorheological differences related to gender in morbidly obese subjects. In this study authors found several hemorheological differences between male and female. In this sense, males showed higher blood viscosity and higher erythrocyte deformability than females and native blood viscosity correlated with several erythrocyte aggregation parameters evaluated with the Laser-Assisted Optical Rotational Cell Analyser (LORCA) [3]. In studies with small sample sizes (18 men and 20 women) there is always the risk that differences in certain variables may appear by chance or by imbalances in th…

Erythrocyte AggregationMalePhysiologybusiness.industryErythrocyte indicesmedia_common.quotation_subjectBlood viscosityPhysiologySmall sampleHematologyMorbidly obeseBlood ViscosityErythrocyte aggregationObesity MorbidPhysiology (medical)Erythrocyte deformabilityMedicineHumansHemorheologyFemaleCardiology and Cardiovascular MedicinebusinessNormalitymedia_commonClinical hemorheology and microcirculation
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Association of erythrocyte deformability with red blood cell distribution width in metabolic diseases and thalassemia trait.

2016

Abstract Increased red blood distribution width (RDW) in anemia is related to disturbances in the cellular surface/volume ratio, usually accompanied by morphological alterations, while it has been shown in inflammatory diseases that the activity of pro-inflammatory cytokines disturbing erythropoiesis increases RDW. Recently it has been reported that higher RDW is related with decreased erythrocyte deformability, and that it could be related with the association of RDW and increased risk of cardiovascular diseases. In order to analyze the influence of morphological alterations and proinflammatory status on the relationship between RDW and erythrocyte deformability, we analyzed erythrocyte de…

Erythrocyte IndicesMalemedicine.medical_specialtyErythrocytesPhysiologyAnemiaThalassemia030204 cardiovascular system & hematologyBiologyProinflammatory cytokine03 medical and health sciences0302 clinical medicinePhysiology (medical)Internal medicineErythrocyte DeformabilitymedicineErythrocyte deformabilityHumansMetabolic SyndromeRed blood cell distribution widthHematologymedicine.diseaseEndocrinology030220 oncology & carcinogenesisImmunologyErythrocyte CountErythropoiesisAnisocytosisThalassemiaMetabolic syndromeCardiology and Cardiovascular MedicineClinical hemorheology and microcirculation
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Estimation of selected skin parameters during a series of beauty treatments in women with acne: a pilot study

2021

Background: Acne vulgaris occurs most often in young people and can significantly decrease the quality of life. Properly selected dermatological therapy and cosmetic procedures can effectively improve the skin condition of acne patients. Aim of the study: The aim of this study was to examine how various cosmetics treatments affect facial sebum levels, skin hydration, and desquamation in young women with acne vulgaris. Material and Methods: 101 women with acne aged 19–29 (M = 22.5 years, SD = 2.3 years) were included in the study. The following cosmetic treatments were used over a 12-week period: intensive pulsing light, alpha-hydroxy acids, cavitation peeling, non-needle mesotherapy, diamon…

Estimationmedicine.medical_specialtySeries (mathematics)business.industrymedia_common.quotation_subjectcavitation peelingmedicine.diseaseDermatologyAHABeautysonophoresismedicineacne vulgarismicrodermabrasionbusinessAcnemedia_commonMedical Science Pulse
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A new preprocessing and control board for the phase 2 electronics of AGATA experiment

2016

The electronics of AGATA HPGe segmented gamma ray detector faces a new challenge in the search of a bigger integration and cost reduction for the phase 2 of the experiment going beyond 45 crystals. This opportunity can be used to introduce a new architecture based on commercial standards while keeping backward compatibility with current electronics. In this sense, new FPGA devices and fast Ethernet links can be used to ease the preprocessing and control task and allowing for processor farms to distribute the processing load. At the same time, modularity should be a key feature of the design in the aim to make it upgradable in time and technology. This paper presents the design of a new prep…

EthernetEngineering010308 nuclear & particles physicsbusiness.industryBandwidth (signal processing)Fast EthernetChange control board01 natural sciencesBackward compatibilityCost reduction0103 physical sciencesElectronic engineeringElectronicsbusinessField-programmable gate array2016 IEEE-NPSS Real Time Conference (RT)
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