Search results for "MCD"

showing 10 items of 58 documents

Multi‐criteria decision‐making approach for modular enterprise resource planning sorting problems

2021

[EN] Implementing Enterprise Resource Planning (ERP) systems is currently recognized as a best practice with wide associated possibilities of business improvement for companies. Integrating these kinds of systems with business processes in the most efficient way requires to endeavour as much as possible simplifications for final users, which can be pursued by optimizing crucial software characteristics. The present article proposes a novel Multi-Criteria Decision-Making (MCDM) approach to deal with such an issue. Specifically, the ELECTRE (ELimination Et Choix Traduisant la REalite) TRI technique is suggested to assign ERP modules into predefined and ordered categories according to maintain…

Operations researchComputer sciencebusiness.industryStrategy and ManagementUsabilityMaintainabilitySortingGeneral Decision SciencesUsabilityModular designMultiple-criteria decision analysisMulti criteria decisionEnterprise resource planningMaintainabilityELECTRE TRIMATEMATICA APLICADAbusinessEnterprise resource planningMCDMJournal of Multi-Criteria Decision Analysis
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An Introduction to Multiobjective Optimization

2016

Multiobjective optimization in industry has rapidly grown in importance, as it provides the possibility for a designer or an engineer to consider the problem in hand as a whole. Solution to a multiobjective optimization problem involves several optimal solutions with different trade-offs. As a result upon optimization s(he) can understand the trade-offs between different solutions and subsequently choose the most preferred solution. In this paper, we provide a bird’s eye view of the different methods available in the literature to solve multiobjective optimization problems. Specifically, in literature there exists at least two different research fields i.e. multiple criteria decision making…

Pareto optimalityEMOMCDM
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Mboat7 down-regulation by hyper-insulinemia induces fat accumulation in hepatocytes.

2020

Background: Naturally occurring variation in Membrane-bound O-acyltransferase domain-containing 7 (MBOAT7), encoding for an enzyme involved in phosphatidylinositol acyl-chain remodelling, has been associated with fatty liver and hepatic disorders. Here, we examined the relationship between hepatic Mboat7 down-regulation and fat accumulation. Methods: Hepatic MBOAT7 expression was surveyed in 119 obese individuals and in experimental models. MBOAT7 was acutely silenced by antisense oligonucleotides in C57Bl/6 mice, and by CRISPR/Cas9 in HepG2 hepatocytes. Findings: In obese individuals, hepatic MBOAT7 mRNA decreased from normal liver to steatohepatitis, independently of diabetes, inflammatio…

Research paperTGFβ Transforming Growth Factor BetaIntracellular SpaceCRISPR Clustered Regularly Interspaced Short Palindromic RepeatshHEPS Human HepatocytesMice0302 clinical medicineLPIAT1DAG Diacylglyceroli.p. Intraperitonealmedia_commonFatty AcidsGeneral Medicine3. Good health030220 oncology & carcinogenesisHOMA-IR homeostasis Model Assessment of Insulin ResistanceMPO morpholinolcsh:Medicine (General)medicine.medical_specialtyPE Phosphatidyl-EthanolamineNashGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciencesTNFα tumor Necrosis Factor AlphaLDL Low Density LipoproteinsHyperinsulinismNAFLDSD Standard Dietmedia_common.cataloged_instanceHumansCPT1 Carnitine Palmitoyltransferase IPhosphatidylinositolGene SilencingEuropean unionVLDL Very Low Density Lipoproteinlcsh:RhHSC Human Hepatic Stellate Cellsmedicine.diseaseLipid MetabolismOA Oleic AcidCI Confidence IntervalMboat7 Membrane bound O-acyltransferase domain containing 7MCD methionine choline deficient diet030104 developmental biologyEndocrinologychemistryCDP Cytidine-DiphosphateFOXO1 Forkhead Box protein O1NAFLD nonalcoholic fatty liver diseaseSteatohepatitisBMI Body Mass IndexCL CardiolipinAcyltransferases0301 basic medicineAlcoholic liver diseaseCXCL10 C-X-C Motif Chemokine 10lcsh:Medicinechemistry.chemical_compoundNon-alcoholic Fatty Liver DiseaseIFG Impaired Fasting GlucoseAPOB Apolipoprotein BNonalcoholic fatty liver diseasePIP Phosphatidyl-Inositol-PhosphateSteatohepatitisqRT-PCR quantitative Real Time Polymerase Chain ReactionMice Knockoutlcsh:R5-920ORO Oil Red O StainingPI PhosphatidylinositolFatty liverTM6SF2 Transmembrane 6 Superfamily Member 2PhospholipidTAG TriglyceridesNASH Nonalcoholic SteatohepatitisLipogenesisLPA Lyso-Phosphatidic AcidPhosphatidylinositolSignal TransductionPS Phosphatidyl-SerinePA Palmitic AcidALD alcoholic liver diseasePC Phosphatidylcholinei.v. IntravenousFATP1 Fatty Acid Transport Protein 1Models BiologicalInternal medicinemedicineAnimalsNonalcoholic fatty liver diseasePPARα Peroxisome Proliferator-Activated Receptor alphaObesityG3P Glyceraldehyde-3-PhosphateSREBP1c Sterol Regulatory Element-Binding Protein 1HDL High Density Lipoproteinsbusiness.industryPI3K Phosphatidylinositol 3 KinaseMembrane ProteinsNHEJ Non-Homologues End JoiningPNPLA3 Patatin-like Phospholipase Domain-containing-3MTTP Microsomal Triglyceride Transfer ProteinLPIAT1 Lysophosphatidylinositol Acyltransferase 1TMC4 Transmembrane Channel-Like 4Disease Models AnimalGene Expression RegulationHepatocytesFOXA2 Forkhead Box A2mTOR mammalian target of RapamycinSteatosisInsulin ResistancebusinessPG Phosphatidyl-GlycerolFABP1 Fatty Acid-Binding Protein 1 FAS Fatty Acid SynthaseT2DM Type 2 Diabetes MellitusEBioMedicine
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Ejaculation Disorders in Male Patients with Cancer: A Systematic Review and Meta-Analysis of Prevalence

2021

PURPOSE: Ejaculatory dysfunction (EjD) and erectile dysfunction after cancer treatment are clinically important complications, but their exact prevalence by various kinds of cancer site and type of treatment is unknown. The aim of this systematic review and meta-analysis was to examine the available evidence and provide pooled estimates for prevalence of EjD and erectile dysfunction in relation to all cancer sites and identify characteristics associated with EjD in cancer patients. MATERIALS AND METHODS: We performed a systematic review and meta-analysis of cross-sectional and case-control studies. We searched 4 electronic databases (Medline®, CINAHL, PsychInfo and Embase®) until July 22, 2…

Retrograde ejaculationmedicine.medical_specialtyejaculationEjaculationbusiness.industryerectile dysfunctionUrologyprevalenceA Systematic Review and Meta-Analysis of Prevalence.- The Journal of urology 2021 [Pizzol D. Trott M. Grabovac I. Yang L. Barnett Y. Parris C. McDermott D. T. Veronese N. Kronbichler A. Ghayda R. A. et al. -Ejaculation Disorders in Male Patients With Cancer]neoplasmsCancermedicine.diseaseCancer treatmentmeta-analysisErectile dysfunctionMale patientInternal medicineMeta-analysisDry Orgasmmedicineejaculation erectile dysfunction meta-analysis neoplasms prevalence Erectile Dysfunction Humans Male NeoplasmsPrevalence Sexual Dysfunction Physiological Ejaculationbusiness
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Introduzione. Mutamenti paradigmatici e nuovi modelli nel dibattito contemporaneo su razionalità, verità e mente.

2008

Searle McDowell Kuhn Gadamer Nietzsche Dennett razionalità verità mente percezione dare e chiedere ragione tribunale dell'esperienza responsabilità cognitiva contenuto concettuale mito del dato.
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Fuzzy ServPerf model combined with ELECTRE III to comparatively evaluate service quality of international airports in Sicily

2015

In this paper a new approach was proposed so as to comparatively evaluate the quality of service alternatives. In particular, a fuzzy extension of the ServPerf service conceptual model was considered to estimate quality scores of fundamental service criteria, whereas the non-compensative multi-criteria decision-making ELECTRE III method was employed to point out the quality ranking of service alternatives on the basis of which the comparative service quality analysis was performed. In order to show the effectiveness of the proposed approach, an empirical study concerning service quality evaluation of the three international airports in Sicily (Italy) was conducted with detailed proposals fo…

Service (business)Service qualityEngineeringOperations researchbusiness.industryStrategy and Managementmedia_common.quotation_subjectQuality of serviceTransportationManagement Monitoring Policy and LawAirport services quality Service quality benchmarking ServPerf model Multi criteria decision making (MCDM) ELECTRE method Fuzzy sets theoryEmpirical researchRankingConceptual modelQuality (business)ELECTREbusinessSettore ING-IND/16 - Tecnologie E Sistemi Di LavorazioneLawmedia_commonJournal of Air Transport Management
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A composite indicator index as a proxy for measuring the quality of water supply as perceived by users for urban water services

2021

Abstract The objective of this study is to develop a composite indicator (CI) to measure the quality of water supply based on the variables that are considered to affect users’ perceptions of water supply quality. The proposed CI includes six relevant aspects that determine users’ perceptions of water supply quality (network quality, water quality, water price, complaints, inconvenience caused by upgrading the network, and continuity of service) in a simple, economical, and objective way, using multi-criteria decision analysis (MCDA) with weights based on data envelopment analysis (DEA). The CI was applied to 32 municipalities in the metropolitan area of Valencia (Spain). The results show t…

Service (business)Water supply qualitybusiness.industryIT service continuitymedia_common.quotation_subjectWater supplyWater economyEconomía AplicadaWater industryEfficiencyEnvironmental economicsMultiple-criteria decision analysisMCDA-DEAManagement of Technology and InnovationData envelopment analysisQuality (business)Water supply managementWater qualityBusiness and International ManagementbusinessApplied Psychologymedia_common
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DEMATEL-based consensual selection of suitable maintenance KPIs

2018

This paper aims to highlight the fundamental role of Multi-Criteria Decision-Making (MCDM) tools to perform efficiently in such a complex field as industrial maintenance. Typically, a strategic plan of maintenance interventions has to be first implemented and then continuously checked by maintenance management. Given the importance to monitor the quality and suitability of the undertaken choices, the Decision-Making Trial and Evaluation Laboratory (DEMATEL) method is herein suggested to evaluate some of the most important maintenance Key Performance Indicators (KPIs) on the basis of their mutual relationships. DEMATEL is particularly adequate to take into account interdependencies existing …

Settore ING-IND/17 - Impianti Industriali MeccaniciDEMATELmaintenance KPIsMCDM
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Quantum computing challenges in the software industry. A fuzzy AHP-based approach

2022

Context The current technology revolution has posed unexpected challenges for the software industry. In recent years, the field of quantum computing (QC) technologies has continued to grow in influence and maturity, and it is now poised to revolutionise software engineering. However, the evaluation and prioritisation of QC challenges in the software industry remain unexplored, relatively under-identified and fragmented. Objective The purpose of this study is to identify, examine and prioritise the most critical challenges in the software industry by implementing a fuzzy analytic hierarchy process (F-AHP). Method First, to identify the key challenges, we conducted a systematic literature rev…

Software process automationMultiple-criteria decision-making (MCDM):Teknologi: 500::Informasjons- og kommunikasjonsteknologi: 550 [VDP]Quantum computingFuzzy analytic hierarchy processVDP::Teknologi: 500::Informasjons- og kommunikasjonsteknologi: 550SoftwareQuantum software requirementComputer Science ApplicationsInformation Systems
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Some consistency issues in multi-criteria decision making

2017

The complexity of decision-making problems included under the multi-criteria decision-making (MCDM) paradigm has favored the proliferation of many schools of thought and varied methodologies. It has not yet been possible to prove the supremacy of any of these approaches. Moreover, in some cases it is difficult to combine the theoretical validity of the approximations with their practical appropriateness. It seems that rigor and applicability are two opposing concepts, something that should not be so. It is our responsibility to bridge the gap. To reduce the gap between theory and practice and use effective methodological approaches, it is necessary to combine the rigor and objectivity of tr…

Strategy and Management1409 Tourism Leisure and Hospitality ManagementOrganizational Behavior and Human Resource ManagementAHPManagement of Technology and InnovationLinearization proceConsistencyBusiness and International ManagementManagement Science and Operations ResearchSafety Risk Reliability and QualityWaste Management and DisposalMCDMIndustrial and Manufacturing Engineering
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