Search results for "MEDICINES"

Estudio de la marca en la prescripción de genéricos en 6 centros de salud durante el año 2001

2003

ObjetivoEstudiar la marca prescrita de los medicamentos genéricos por los médicos de familia de 6 centros de salud de un área de atención primaria mediante el análisis de las recetas facturadas durante el año 2001.DiseñoEstudio descriptivo de la prescripción por receta médica.EmplazamientoÁrea de salud de atención primaria.Participantes/contextoSeis centros de salud, 3 de ubicación urbana y 3 de ubicación metropolitana.MétodoAnálisis de la prescripción farmacéutica a través del proceso de facturación de las recetas médicas con la ayuda del gestor para la prestación farmacéutica GAIA. El estudio se ha realizado con el 50% del total de los envases de medicamentos de alguna especialidad farmac…

Consumo de hierbas medicinales y medicamentos

2001

ObjetivoDada la posibilidad de efectos adversos, interacciones con medicamentos e intoxicaciones por contaminantes entre consumidores de hierbas medicinales (HM), nuestro objetivo es describir el consumo de HM en usuarios de los centros de salud en tratamiento con medicamentos.DiseñoEstudio observacional, transversal.EmplazamientoTrece centros de salud de la Comunidad Valenciana.Pacientes u otros participantesUsuarios, de sexo indistinto, mayores de 14 años, seleccionados para un estudio de utilización de medicamentos para encontrar diferencias entre sexos. Mediciones y resultados principales. Las variables de estudio, edad, sexo, nivel educativo, consumo de medicamentos y uso de HM se reco…

Media and Science Policy: Who Influences Whom Regarding Complementary and Alternative Medicines Regulation

2021

This paper analyses the synergies between press and politics in the debate on the regulation of complementary and alternative medicines (CAM) in Spain between 1979 and 2018. We argue that longitudinal analysis and comparison of this interaction and synergy reveal how the mainstream discourse has shifted. We use a dataset of news ( N  =  2,059), a news sample ( n  =  325) and a dataset of parliamentary records ( N  =  86). Using both quantitative and qualitative approaches, the dynamics of the interaction between the different institutions and actors involved is assessed. Specifically, the study analyses the media and parliamentary attention to CAM issues (agenda setting), how CAM is addres…

SPIONs embedded in polyamino acid nanogels to synergistically treat tumor microenvironment and breast cancer cells.

2018

Abstract The extremely complex tumor microenvironment (TME) in humans is the major responsible for the therapeutic failure in cancer nanomedicine. A new concept of disease-driven nanomedicine, henceforth named “Theranomics”, which attempts to target cancer cells and TME on the whole, represents an attractive alternative. Herein, a nanomedicine able to co-deliver doxorubicin and a tumor suppressive proteolytic protein such as collagenase-2 was developed. We successfully obtained superparamagnetic nanogels (SPIONs/Doco@Col) via the intermolecular azide-alkyne Huisgen cycloaddition. We demonstrated that a local ECM degradation and remodeling in solid tumors by means of collagenase-2 could enha…

Psychotropic drugs and driving: prevalence and types

2013

Background Some psychotropic medications (e.g., benzodiazepines, sedative antidepressants, etc.) may impair cognitive and psychomotor functions and, therefore, endanger traffic safety (Ravera, Br J Clin Pharmacol, 72(3):505–513, 2011). They affect detection, registration, and information processing, problem solving, and decision-making processes, and they also affect emotional and social aspects. The objective of this research was to clarify three closely related issues that are significant for traffic safety: the prevalence of psychotropic drugs on driving, the most frequently used psychotropic drugs to treat depression, anxiety, insomnia, or any tranquilizers (whether it is a medical pres…

Alnus glutinosa (L.) Gaertn. and Alnus cordata (Loisel) Duby as new sources of safe cosmetic and pharmacological anti-melanogenic agents

2018

The genus Alnus (Betulaceae) comprises many species with a long history in traditional medicines. The crude extracts and isolated compounds from Alnus species exhibit a wide spectrum of in vitro and in vivo pharmacological activities (1). Phytochemical investigations revealed the presence of diarylheptanoids, a class of natural products typically found in Alnus genus with two aryl groups joined by a heptane chain in the main skeleton that have drawn attention due to their multiple biological properties and their therapeutic potential (2). A previous study reported that oregonin and other structurally analogous diarylheptanoids isolated from the bark of A. hirsuta showed inhibitory effects o…

USE OF HERBAL REMEDIES AMONG CANCER AND TRANSPLANT PATIENTS IN THE TOWN OF PALERMO, SICILY

2010

Concomitant use of herbal remedies may lead to toxicity or failure of conventional therapies in different patients. The objectives of this survey were to assess: (1) the prevalence of the use of vegetal remedies by cancer and transplanted patients (2) the level of communication about such use to the physicians (3) whether such use might be associated to adverse reactions or interactions with conventional drugs. The study was carried out on 100 consecutive cancer patients attending the outpatient medical oncology clinic of the University Hospital "P. Giaccone", Palermo and on other 100 transplanted patients who were hospitalized or followed up at ISMETT, Palermo. Another group was composed o…

“The European Medicines Agency (EMEA) guideline on oncology drug development”

2007

Medikamentu administrēšana vispārējās aprūpes nodaļā

2021

Bakalaura darba tēma – „Medikamentu administrēšana vispārējās aprūpes nodaļā” aktualitāte pamatota ar to, ka mūsdienās arvien vairāk parādās kļūdas medikamentu administrēšanā. Bakalaura darba mērķis ir noskaidrot kāda ir medikamentu administrēšana vispārējas aprūpes nodaļās. Darbā ir izvēlēta kvantitatīvā pētniecības metode – anketa. Darba hipotēze ir apstiprinājusies daļēji, jo pastāv kļūdu iespēja pareizā medikamentu administrēšanā vispārējās aprūpes nodaļā, kas var ietekmēt pacientu atveseļošanos. Atslēgas vārdi: medikamenti, administrēšana, vispārējās aprūpes nodaļa.

Synergistic Anticancer Therapy by Ovalbumin Encapsulation-Enabled Tandem Reactive Oxygen Species Generation

2020

Abstract The anticancer efficacy of photodynamic therapy (PDT) is limited due to the hypoxic features of solid tumors. We report synergistic PDT/chemotherapy with integrated tandem Fenton reactions mediated by ovalbumin encapsulation for improved in vivo anticancer therapy via an enhanced reactive oxygen species (ROS) generation mechanism. O2 .− produced by the PDT is converted to H2O2 by superoxide dismutase, followed by the transformation of H2O2 to the highly toxic .OH via Fenton reactions by Fe2+ originating from the dissolution of co‐loaded Fe3O4 nanoparticles. The PDT process further facilitates the endosomal/lysosomal escape of the active agents and enhances their intracellular deliv…