Search results for "MICI"
showing 10 items of 1671 documents
Un texto académico del ocaso del siglo XVII: el "Discurso sobre el microscopio" de José Ortí y Moles (Estudio y edición)
2010
El Discurso sobre el microscopio del Dr. José Ortí Moles (1650-1728) es el texto de una conferencia impartida en Valencia a finales del siglo XVII. Su autor un conocido jurista, dramaturgo y poeta fue invitado por alguna de las academias a las que perteneció ¿del Conde de la Alcudia? ¿Valenciana? a disertar sobre un tema que supuestamente dominaba como amateur. La exposición superficial, obsoleta, sesgada hacia la metáfora político-moral y basada en la obra de los jesuitas PP. Kircher, Schott y Milliet Dechales nos proporciona un magnífico testimonio del estado de conocimientos y del grado de aspiraciones intelectuales alcanzado por las academias valencianas de notables. (A)
Review & meta-analysis: isopropanolic black cohosh extract iCR for menopausal symptoms - an update on the evidence
2020
A systematic literature search revealed 35 clinical studies and one meta-analysis comprising 43,759 women, of which 13,096 were treated with isopropanolic Cimicifuga racemosa extract (iCR). Compared to placebo, iCR was significantly superior for treating neurovegetative and psychological menopausal symptoms, with a standardized mean difference of 0.694 in favor of iCR (p<0.0001). Effect sizes were larger when higher dosages of iCR as monotherapy or in combination with St. John's wort (Hypericum perforatum [HP]) were given ( 1.020 and 0.999, respectively), suggesting a dose-depend- ency. For psychological symptoms, the iCRþHP combination was superior to iCR monotherapy. Efficacy of iCR was c…
Isopropanolic Cimicifuga racemosa is favorable on bone markers but neutral on an osteoblastic cell line
2009
Postmenopausal women treated with an isopropanolic extract of Cimicifuga racemosa underwent a decrease in the urinary concentration of N-telopeptides, a marker of bone resorption, and an increase in alkaline phosphatase, a marker of bone formation, at the third month of therapy. Serum from treated women did not modify the activity of alkaline phosphatase or the expression of three genes, runt-related transcription factor-2 (Runx-2), alkaline phosphatase, and osteocalcin, when added to the MC3T3-E1 osteoblastic cell line.
Microwave-assisted chemical modification of g-C3N4 for photoinduced processes: organic degradation, hydrogen production and selective oxidation of al…
2023
g-C3N4 powders were treated by means of the microwave technique in three different aqueous and organic media (HNO3, NaOH and N,N-dimethylformamide). All powders were analyzed by XRD reveling that g-C3N4 maintains its structure. The morphology of the samples was analyzed with scanning electron microscopy, where the micrographs reveals that the modifcation occurs on the surface of the g-C3N4. The photocatalytic activity of the samples was evaluated in the degradation of ciprofoxacin, hydrogen production and for the selective partial oxidation of 4-methoxybenzylalcohol (4-MBA) to its aldehyde. The sample treated with HNO3 (C3N4-HNO3) shows the best photocatalytic performance in the degradation…
Le modifiche all'articolo 577 del codice penale (art. 11, l. 19 luglio 2019, n. 69)
2020
Il contributo si sofferma sulle modifiche all'art. 577 c.p., dovute all'art. 11 della legge 19 luglio 2019, n. 69.
Characterization of gramicidin A in an inverted micellar environment. A combined high-performance liquid chromatographic and spectroscopic study
1992
We have investigated the conformational adaptability of gramicidin A incorporated into reverse micelles of sodium bis(2-ethylhexyl)sulfosuccinate (AOT)/isooctane/water, a so far unexplored "host" membrane-mimetic model system for this peptide. A high-performance liquid chromatographic strategy previously developed for the study of gramicidin in phospholipid vesicles and normal micelles [Bañó et al. (1989) FEBS Lett. 250, 67; Bañó et al. (1991) Biochemistry 30, 886] has been successfully extended to this system. The method has permitted the separation of peptide conformational species, namely, double-stranded dimers and monomers, and an accurate quantitation of their proportion in the invert…
Conformational transitions of gramicidin A in phospholipid model membranes. A high-performance liquid chromatography assessment.
1991
We have investigated the conformation of gramicidin A reconstituted in different phospholipid environments, small unilamellar vesicles, extensive bilayers, and micelles by exploiting a recently proposed experimental approach based on high-performance liquid chromatography [Bano et al. (1988) J. Chromatogr. 458, 105; Bano et al. (1989) FEBS Lett. 250, 67]. The method allows the separation of conformational species of the peptide namely, antiparallel double-stranded (APDS) dimers and β 6.3 -helical monomers, and quantitation of their proportions in the lipid environment. Various experimental parameters (e.g., nature of organic solvent, time of incubation in organic solvent, lipid-to-peptide m…
Carboxylated-xyloglucan and peptide amphiphile co-assembly in wound healing.
2021
Abstract Hydrogel wound dressings can play critical roles in wound healing protecting the wound from trauma or contamination and providing an ideal environment to support the growth of endogenous cells and promote wound closure. This work presents a self-assembling hydrogel dressing that can assist the wound repair process mimicking the hierarchical structure of skin extracellular matrix. To this aim, the co-assembly behaviour of a carboxylated variant of xyloglucan (CXG) with a peptide amphiphile (PA-H3) has been investigated to generate hierarchical constructs with tuneable molecular composition, structure, and properties. Transmission electron microscopy and circular dichroism at a low c…
A semi-empirical approach for the simulation of circular dichroism spectra of gramicidin A in a model membrane
1992
In an extension of our previous work (Bañó, M. C., Braco, L., and Abad, C. 1991. Biochemistry. 30:886-94), the kinetics of dissociation of gramicidin A double-stranded dimers into beta 6.3-helical monomers in small unilamellar vesicles prepared following different protocols, were investigated using in combination circular dichroism (CD) and high-performance liquid chromatography (HPLC). The analysis of the data from both techniques according to a two-component model strongly supports that any given CD pattern of gramicidin incorporated in the phospholipid bilayer can be deconvoluted essentially as a linear combination of the reference subspectra calculated for the double-stranded dimer and …
HPLC study on the ‘history’ dependence of gramicidin A conformation in phospholipid model membranes
1989
AbstractA novel HPLC methodology for the study of gramicidin A reconstituted in model membranes has been tested in comparison with circular dichroism data. It is shown that this chromatographic technique not only corroborates most of the recent spectroscopic results but allows one to explain them in terms of mass fractions of different actual conformational species of GA in the phospholipid assemblies. In particular, the dependence of the inserted peptide configuration on the organic solvent and other parameters involved in the ‘history’ of the sample preparation and handling has been analyzed by HPLC in two phospholipid model systems: small unilamellar vesicles and micelles. Moreover, a sl…