Search results for "MMA"

showing 10 items of 13609 documents

Socializācijas sekmēšana 1.klašu skolēniem ar smagiem garīgiem attīstības traucējumiem

2020

Diplomdarba temats: „Socializācijas sekmēšana 1. klašu skolēniem ar smagiem garīgiem attīstības traucējumiem” Pētījums veikts ar mērķi atklāt piemērotākās pieejas skolēnu ar garīgās attīstības traucējumiem socializācijas sekmēšanai speciālās izglītības iestādes pedagoģiskā procesa ietvaros. Lai sasniegtu minēto mērķi, darbā teorētiski pētīta skolēnu ar smagiem garīgās attīstības traucējumiem (GAT) attīstības raksturojums un pedagoģiskās iespējas, galveno uzmanību pievēršot skolēnu socializācijas dažādiem aspektiem, kuras sekmēšanas pedagoģiskais pamatuzdevums ir nodrošināt maksimāli iespējamo skolēnu patstāvību. Empīriskajā daļā raksturots pedagoģiskā darba īpatnības četros pamatvirzienos: …

sākumskolas skolēni ar smagiem garīgās attīstības traucējumiemPedagoģijaorientācija sociālā vidēpašapkalpošanās un higiēnas prasmessocializācijapiktogrammas
researchProduct

Dexamethasone premedication suppresses vaccine-induced immune responses against cancer

2020

ABSTRACT Glucocorticosteroids (GCS) have an established role in oncology and are administered to cancer patients in routine clinical care and in drug development trials as co-medication. Given their strong immune-suppressive activity, GCS may interfere with immune-oncology drugs. We are developing a therapeutic cancer vaccine, which is based on a liposomal formulation of tumor-antigen encoding RNA (RNA-LPX) and induces a strong T-cell response both in mice as well as in humans. In this study, we investigated in vivo in mice and in human PBMCs the effect of the commonly used long-acting GCS Dexamethasone (Dexa) on the efficacy of this vaccine format, with a particular focus on antigen-specif…

t-cell primingPremedicationmedicine.medical_treatmentImmunologyPriming (immunology)dexamethasoneglucocorticosteroidsProinflammatory cytokineMice03 medical and health sciences0302 clinical medicineImmune systemAntigenCancer immunotherapyNeoplasmsAnimalsHumansImmunology and AllergyMedicineRC254-282Original ResearchMice Inbred BALB Ccancer immunotherapybusiness.industryrna vaccineImmunityNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC581-607Mice Inbred C57BLCytokineOncology030220 oncology & carcinogenesisImmunologyt-cell vaccineFemaleCancer vaccineImmunologic diseases. AllergybusinessT-cell vaccineResearch Article030215 immunologyOncoImmunology
researchProduct

Genetic Factors as Promising Biomarkers of Sporadic Ascending Aortic Aneurysm

2014

Thoracic aorta shows various changes with advancing age and a progressive deterioration in structure and function. As a result, vascular remodeling (VR) and medial degeneration (MD) occur. VR and MD are typical entities of sporadic thoracic aortic aneurysm (TAA), actually considered a common and serious health risk and a pathology by unclear mechanisms. Increased activity of the coagulation system, inflammation, activation of extracellular matrix remodeling and endothelial dysfunction pathways have been recently evidenced to have a key role in its onset. Thus, polymorphisms of the coagulation system [fibrinogen (rs1800790); Factor II ( rs1799963); Factor V (rs6025); Factor VII (rs121964926)…

tPA ( rs2020918)ACE (rs1799752)]PAI-1 (rs1799768)TAFI (rs2146881)] inflammation [TLR4 (rs4986790)Factor V (rs6025)CCR5 (rs333)] extra-cellular matrix remodeling [MMP9 (rs3918242)vascular remodeling (VR) and medial degeneration (MD)sporadic thoracic aortic aneurysm (TAA)polymorphisms of the coagulation system [fibrinogen (rs1800790)MMP2 (rs243865)] endothelium dysfunction [eNOs (rs 1799983)Factor II ( rs1799963)Factor VII (rs121964926)
researchProduct

The Reform of Vocational Education and Training in Finland: Insights from Twitter

2018

This paper aims to analyse and describe relationships and communication in Twitter in relation to vocational education and training reform in Finland. Data were collected during the early implementation phase of the reform from January 2018 to early June 2018. The data included 2400 tweets containing the hashtag #amisreformi (VET reform). Social network analysis was utilised to study the network and communities. The main themes of the tweets were analysed using thematic analysis, and automated sentiment analysis was used to examine the tones of the tweets and public opinion. The study showed that the official actors were central influencers in the network that lacked connectivity. Overall, …

ta113ammatillinen koulutussocial mediaTwittervocational educationsosiaalinen mediayleinen mielipide113 Computer and information sciencesammattikoulutuspublic opinionuudistukset516 Educational sciencesreform
researchProduct

Elementary Math to Close the Digital Skills Gap

2018

All-encompassing digitalization and the digital skills gap pressure the current school system to change. Accordingly, to ’digi-jump’, the Finnish National Curriculum 2014 (FNC-2014) adds programming to K-12 math. However, we claim that the anticipated addition remains too vague and subtle. Instead, we should take into account education recommendations set by computer science organizations, such as ACM, and define clear learning targets for programming. Correspondingly, the whole math syllabus should be critically viewed in the light of these changes and the feedback collected from SW professionals and educators. These findings reveal an imbalance between supply and demand, i.e., what is ove…

ta113effectiveness of educationmatematiikkaComputer sciencetaidotDigital skillsdigital skills gaptietotekniikkaElementary mathematicscontinuous vs. discrete mathcomputing in math syllabusprofessional development of software professionalsMathematics educationammattitaitoK-12 computer science education
researchProduct

Habituating Students to IPR Questions During Creative Project Work

2017

ta113opiskelijatstudentscopyrightprojektioppiminenopen dataintellectual property lawCreative projecttekijänoikeusWork (electrical)project learningimmateriaalioikeusEngineering ethicsta516Sociologyavoin tieto
researchProduct

Social support in the workplace for physicians in specialization training

2018

ABSTRACT When becoming a specialist, learning-through-service plays a significant role. The workplace affords good opportunities for learning, but the service-learning period may also impose stress on phycisians in specialization training. In medical work, social support has proved to be a very important factor in managing stress. Social support may afford advantages also for learning and professional identity building. However, little was known about how social support is perceived by doctors in specialization training. This study aimed to understand the perceptions of physicians in specialization training regarding social support communication in their workplace during their learning-thro…

ta520020205 medical informaticsWorkplace relationshipsworkplace interactionIdentity (social science)continuing medical educationworkplace relationships02 engineering and technologyammatti-identiteettiOccupational Stress0302 clinical medicineContinuing medical educationMuut yhteiskuntatieteet - Other social sciencestyössäoppiminen0202 electrical engineering electronic engineering information engineeringTerveystiede - Health care science030212 general & internal medicineta518Situational ethicsWorkplaceta316lcsh:LC8-6691lcsh:R5-920työelämän suhteetEducation MedicalCommunicationGeneral MedicinePsychologylcsh:Medicine (General)SpecializationResearch Articlejatkuva oppiminensairaalatvuorovaikutusAttitude of Health Personnellearning through serviceControl (management)sosiaalinen tukiContinuing medical educationEducation03 medical and health sciencesSocial supportSpecialization (functional)HumansInterpersonal RelationsMedical educationlcsh:Special aspects of educationelinikäinen oppiminentyöpaikatstressisocial supportSocial relationMedia- ja viestintätieteet - Media and communicationshoitohenkilöstöphysicians in specialization trainingPerception
researchProduct

Foreign captains in elite hockey markets: mediatized discourses of professionalization between routes and roots

2018

The commercial internationalization of professional ice hockey is shaped by tensions of (re)routing and (up)rooting since it involves (i) crossing geographic, ethnic, and linguistic boundaries to c...

ta520Cultural StudiesjääkiekkojääkiekkoilijatrajatEthnic groupta6121ProfessionalizationulkomaalaisetIce hockeyvoitotice hockeytahtoPolitical scienceSuomi0502 economics and businesskielimaantiedeta315060201 languages & linguisticskielitiedelahjakkuus05 social sciencesammattiurheilutaidotammatillisuus06 humanities and the artsInternationalizationKanadaammatillinen kehitysPolitical economy0602 languages and literatureEliteetnisyys050212 sport leisure & tourismSport in Society
researchProduct

Agentic perspective on fostering work-related learning

2017

Despite the increased recognition of the role that professional agency plays in work-related learning, little is known about what supports it. Based on current theoretical notions, the first purpose of this paper is to show that professional agency is closely intertwined with work-related learning. The second purpose is to introduce some main principles that promote professional agency and describe three work-related training settings that are aimed at fostering learning by taking into account agentic perspectives. These complementary settings include an identity coaching programme, a leadership coaching programme, and a work conference. Based on the qualitative meta-synthesis, the paper fu…

ta520Higher educationtraining settingsoppiminenCoachingProfessional studiesExperiential learningWork relatedEducationammatti-identiteettiProfessional learning community0502 economics and businessPedagogyAgency (sociology)työssäoppiminenta516professional identitybusiness.industry05 social sciences050301 educationprofessional agencytoimijuusammatillinen toimijuuswork-related learningbusinessPsychology0503 education050203 business & managementQualitative research
researchProduct

Moral distress among social workers : the role of insufficient resources

2015

The present study examined moral distress among Finnish social workers and the role of perceived resource insufficiencies in explaining it. The aim was to shed light on this understudied phenomenon in the field of social welfare. The study focused on work-related moral distress, defined as impaired wellbeing that is connected to the continual inability to implement actions that one considers morally appropriate. The survey data were collected with an electronic questionnaire between the years 2011 and 2012. The respondents (n = 817) were social workers in the public social welfare services and the overall response rate was 46.5 per cent. Nearly 11 per cent of the respondents reported experi…

ta520Resource (biology)Sociology and Political SciencetyöhyvinvointiammattietiikkaSocial Welfareresurssit050906 social workmoral distressPhenomenonMoral distress0501 psychology and cognitive scienceswork-related wellbeingSocial worksocial welfare professionals05 social sciencesta5142sosiaalityöntekijäthumanitiesSick leaveProfessional ethicsSurvey data collection0509 other social sciencesprofessional ethicsPsychologySocial psychology050104 developmental & child psychologyInternational Journal of Social Welfare
researchProduct