Search results for "MOTILITY"
showing 10 items of 303 documents
Beeinflussung der Darmmotorik durch Xylit
1963
Mit Hilfe der Tuschetransportmethode wurde an Mausen die Darmwirksamkeit von Xylit gepruft. Durch perorale Xylitgaben in Mengen von 0,5–1,0 g/kg Korpergewicht wurde die Darmtatigkeit deutlich angeregt. Kleinere Xylit-Dosen hatten demgegenuber keinen Einflus auf die Darmperistaltik. Die Anregung der Darmmotorik durch hohe Xylitgaben wird als osmotischer Effekt gedeutet.
Lemon Oils Attenuate the Pathogenicity of Pseudomonas aeruginosa by Quorum Sensing Inhibition
2021
The chemical composition of three Citrus limon oils: lemon essential oil (LEO), lemon terpenes (LT) and lemon essence (LE), and their influence in the virulence factors production and motility (swarming and swimming) of two Pseudomonas aeruginosa strains (ATCC 27853 and a multidrug-resistant HT5) were investigated. The main compound, limonene, was also tested in biological assays. Eighty-four compounds, accounting for a relative peak area of 99.23%, 98.58% and 99.64%, were identified by GC/MS. Limonene (59–60%), γ-terpinene (10–11%) and β-pinene (7–15%) were the main compounds. All lemon oils inhibited specific biofilm production and bacterial metabolic activities into biofilm in a dose-dep…
In Vivo Imaging of Enteric Neuronal Networks in Humans Using Confocal Laser Endomicroscopy
2012
Tu1656 Endomicroscopy of Intramuscular Neuronal Network Using Confocal Laser Endomicroscopy: A New Diagnostic Approach for Enteral Motility Disorders
2012
Dynamics and interactions of parvoviral NS1 protein in the nucleus
2007
Summary Nuclear positioning and dynamic interactions of viral proteins with nuclear substructures play essen- tial roles during infection with DNA viruses. Visual- ization of the intranuclear interactions and motility of the parvovirus replication protein (NS1) in living cells gives insight into specific parvovirus protein- cellular structure interactions. Confocal analysis of highly synchronized infected Norden Laboratory Feline Kidney cells showed accumulation of nuclear NS1 in discrete interchromosomal foci. NS1 fused with enhanced yellow fluorescence protein (NS1- EYFP) provided a marker in live cells for dynamics of NS1 traced by photobleaching techniques. Fluo- rescence Recovery after…
Chemotaxis and Haptotaxis on Cellular Level
2018
Chemotaxis and haptotaxis have been a main theme in the macroscopic study of bacterial and cellular motility. In this work, we use a successful model that describes cellular motility and investigate the influence these processes have on the shape and motility of fast migrating cells. We note that, despite the biological and modelling differences of chemotaxis and haptotaxis, the cells exhibit many similarities in their migration. In particular, after an initial adjustment phase, the cells obtain a stable shape, similar in both cases, and move with constant velocity.
Deguna vārsta kustīguma kvantitatīvo noteikšanas metožu salīdzinoša analīze
2019
Ievads 4-fāžu rinomanometrija šobrīd ir vienīgā nazālo elpceļu funkcionalitātes mērīšanas metode, kura ņem vērā nazālo elpceļu elastīgās struktūras. Sekojot līdz jaunākajiem atklājumiem par to kā nazālās vārstules kustīgums iedarbojas jau agri elpošanas ciklā, fundamentāli ir izveidot ilgtspējīgu diagnostikas instrumentu, kas mēra nazālo elpceļu elastīgās struktūras, it īpaši deguna vārstules. Mērķis Šī pilotpētījuma mērķis ir virzīt uz priekšu zinātnisko pētniecību fizioloģiskas un patoloģiskas deguna gaisa plūsmas diagnostikā. Mērķis ir attīstīt provizoriskas mērīšanas tehnikas, kas veicinātu nazālās vārstules elastogrāfijas ierīces ieviešanu medicīnā. Materiāli un metodes Tika testēti da…
Role of NK1 and NK2 receptors in mouse gastric mechanical activity
2006
1. The aim of the present study was to examine the role of NK1 and NK2 receptors in the control of mechanical activity of mouse stomach. In this view, the motor effects induced by NK1 and NK2 receptor agonists and antagonists were analyzed, measuring motility as intraluminal pressure changes in mouse-isolated stomach preparations. In parallel, immunohistochemical studies were performed to identify the location of NK1 and NK2 receptors on myenteric neurons and smooth muscle cells. 2. Substance P (SP) induced biphasic effects: a contraction followed by relaxation; neurokinin A (NKA) and [beta-Ala8]-NKA(4-10), selective agonist of NK2 receptors, evoked concentration-dependent contractions, whe…
Unraveling the behavior of oral drug products inside the human gastrointestinal tract using the aspiration technique: History, methodology and applic…
2020
Fluid sampling from the gastrointestinal (GI) tract has been applied as a valuable tool to gain more insight into the fluids present in the human GI tract and to explore the dynamic interplay of drug release, dissolution, precipitation and absorption after drug product administration to healthy subjects. In the last twenty years, collaborative initiatives have led to a plethora of clinical aspiration studies that aimed to unravel the luminal drug behavior of an orally administered drug product. The obtained drug concentration-time profiles from different segments in the GI tract were a valuable source of information to optimize and/or validate predictive in vitro and in silico tools, freque…