Search results for "Macro"
showing 10 items of 3471 documents
Outlining the impact of intellectual capital accumulation and depletion processes on the performance of an insurance firm: a dynamic resource-based p…
2014
This paper aims to develop a conceptual framework on how Intellectual Capital (IC) accumulation and depletion processes are dynamically interrelated with firm performance. Such a framework makes explicit the relationships between policy levers, strategic resources, drivers, end-results and performance indicators through a Dynamic Resource-based perspective. Such an approach matches the Resource based perspective and the System Dynamics (SD) methodology. This paper argues that in order to explain a firm superior performance, it is not sufficient to look at the endowment of strategic resources in a given moment of time; it is instead required to investigate the dynamics of company strategic r…
Revisited mixed-value method via symmetric BEM in the substructuring approach
2012
Abstract Within the Symmetric Boundary Element Method, the mixed-value analysis is re-formulated. This analysis method contemplates the subdivision of the body into substructures having interface kinematical and mechanical quantities. For each substructure an elasticity equation, connecting weighted displacements and tractions to nodal displacements and forces of the same interface boundary and to external action vector, is introduced. The assembly of the substructures is performed through both the strong and weak regularity conditions of the displacements and tractions. We obtain the solving equations where the compatibility and the equilibrium are guaranteed in the domain Ω for the use of…
Comparison of the effect of different medicaments on surface reproduction of two commercially available Polyvinyl Siloxane impression materials - An …
2013
Objective:To determine the effect of different retraction cord medicaments on surface detail reproduction of polyvinyl siloxane impression materials and compare this effect on any two brands of commercially available polyvinyl siloxane impression materials. Material and methods: Four stainless steel dies were made according to ADA specification no.19. Three dies were treated with aluminium chloride (5%), ferric sulphate (13.3%) and epinephrine (0.1%) while the fourth one was left untreated to serve as control. Two impression materials (Dentsply and 3M ESPE) were used. Results: All the three medicaments adversely affected the surface detail reproduction of both the brands of the polyvinyl si…
Investment and Control Decisions in Foreign Markets: Evidence from Service Industries
2010
We empirically investigate the entry mode choice in the service sector. In contrast to current models, we propose a model for choice of entry mode that breaks down the decision into two levels of analysis: first, at the more macro level, the choice of the degree of commitment is influenced mainly by country-related variables; second, at the more micro level, the choice of the degree of control is addressed by firm-related variables. Based on a sample of 328 foreign market entries, our study contributes to the literature of entry mode in two ways: first, by showing the explanatory capacity of the hierarchical model in the analysis of entry mode choice in the service sector; and second, throu…
For Whom is MAI? A Theoretical Perspective on Multilateral Agreements on Investments
2001
Why do we observe some LDCs objecting the prospect of a Multilateral Agreement on Investment (MAI), although they have been keen to liberalize investment in preferential agreements in recent years? In this paper, we analyse the issue of MAI implementation and assess the welfare consequences of such kind of agreements. In our model, participation to MAI involves a trade-off between less rent extraction from multinational firms (MNEs) and more abundant FDI inflows. At equilibrium, either all countries enter MAI, or all countries stay out, or only some of them enter. Coordination problems may induce multiple equilibria: the three typesof equilibria may coexist. So, the implementation of MAI ma…
B cells assume the command
2015
A proinflammatory B cell cytokine activates autoimmunity, and B cell depletion treats multiple sclerosis (Li et al., this issue).
An Effective Double Sampling Scheme for thecControl Chart
2013
In the present paper is developed a statistical process control inspection procedure based on a new simple-to-implement and effective double sampling scheme for the c control chart, aimed at the minimization of the number of inspected observation units and warranting fixed levels for the type I and II error risks. In particular, the formulations of the false alarm risk α, the power P of the chart, and the expected number of inspected observation units for the developed inspection procedure are given, whereas a macro of Microsoft Excel is adopted to solve the tackled problem. In order to illustrate the application of the developed approach and to investigate on the influence of several opera…
CCDC 1524058: Experimental Crystal Structure Determination
2017
UDAKUI : 6,12,18,24-tetramethoxy-2,8,14,20-tetrapropyl-4,10,16,22-tetrahydroxycalix[4]arene acetone solvate Space Group: P21/n, Cell: a 11.7707(4)Å b 17.4447(6)Å c 21.7775(7)Å, α 90.00° β 105.261(2)° γ 90.00° Work published 2017 via Cambridge Crystallographic Data Centre.
Alfavīrusu vektoru izstrāde makrofāgu aktvācijai vēža imunoterapijā
2016
Audzēju-iefiltrējošiem makrofāgiem piemīt gan spēja veicināt audzēja attīstību, gan inhibēt, attiecībā no to aktivācijas stāvokļa. In vitro pētījumos ir ticis parādīts, ka, iedarbojoties ar interferonu-g (IFN-γ) kopā ar Toll-like receptora (TLR) ligandu, tika ierosināts M1 makrofāgu fenotips, kas tiek asociēts ar audzēja iznīcināšanu. Audzēja imūnterapiju varētu nodrošināt M1 makrofāgu fenotipa inducēšana audzēju-iefiltrējošos makrofāgos. Šajā darbā mēs izvērtējām Semliki meža vīrusa (SFV) vektoru potenciālu makrofāgu aktivācijā pret vēzi. SFV tika izmantots, lai konstruētu replikācijas defektīvus konstruktus ar ieklonētiem peļu audzēja nekrozes faktora (mTNFα), peļu IFNγ un cilvēka IFNγ gē…
Instruction of haematopoietic lineage choices, evolution of transcriptional landscapes and cancer stem cell hierarchies derived from an AML1-ETO mous…
2013
The t(8;21) chromosomal translocation activates aberrant expression of the AML1-ETO (AE) fusion protein and is commonly associated with core binding factor acute myeloid leukaemia (CBF AML). Combining a conditional mouse model that closely resembles the slow evolution and the mosaic AE expression pattern of human t(8;21) CBF AML with global transcriptome sequencing, we find that disease progression was characterized by two principal pathogenic mechanisms. Initially, AE expression modified the lineage potential of haematopoietic stem cells (HSCs), resulting in the selective expansion of the myeloid compartment at the expense of normal erythro- and lymphopoiesis. This lineage skewing was foll…