Search results for "Magydaris"

showing 3 items of 3 documents

Cytotoxic Activity and Composition of Petroleum Ether Extract from Magydaris tomentosa (Desf.) W. D. J. Koch (Apiaceae)

2015

The petroleum ether extract of Magydaris tomentosa flowers (Desf.) W. D. J. Koch has been analyzed by GC-MS. It is mainly constituted by furanocoumarins such as xanthotoxin, xanthotoxol, isopimpinellin, and bergaptene. Other coumarins such as 7-methoxy-8-(2-formyl-2-methylpropyl) coumarin and osthole also occurred. The antiproliferative activity of Magydaris tomentosa flower extract has been evaluated in vitro on murine monocye/macrophages (J774A.1), human melanoma (A375) and human breast cancer (MCF-7) tumor cell lines, showing a major activity against the latter.

AlkanePharmaceutical ScienceAnalytical ChemistryMicechemistry.chemical_compoundxanthotoxinDrug DiscoveryCytotoxic T cellPetroleum etherSettore BIO/15 - Biologia FarmaceuticaCell DeathbiologyTraditional medicineisopimpinellinxanthotoxolFlowerChemistry (miscellaneous)Molecular MedicineHumanIsopimpinellinFlowersCoumarinMagydaris tomentosaGas Chromatography-Mass SpectrometryArticlePlant Extractfuranocoumarinslcsh:QD241-441<i>Magydaris tomentosa</i>ostholelcsh:Organic chemistryCell Line TumorFuranocoumarinAlkanesBotanyAnimalsHumansPhysical and Theoretical Chemistryether extractMagydaris tomentosa; coumarins; furanocoumarins; xanthotoxin; xanthotoxol; isopimpinellin; osthole; bergaptene; MCF-7Cell ProliferationApiaceaecoumarinsAnimalPlant ExtractsOrganic ChemistrySettore CHIM/06 - Chimica Organicabiology.organism_classificationCoumarinIn vitrochemistryMCF-7XanthotoxolMCF-7ApiaceaebergapteneMolecules
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A new irregular diterpenoid of biogenetic interest from the flowers of Magydaris tomentosa (Desf.) DC. (Apiaceae)

2007

A new irregular acyclic diterpene, magytomol acetate (2), has been isolated from the light petroleum extract of the flowers of Magydaris tomentosa (Desf.) DC. (Apiaceae) and its structure has been elucidated by means of extensive spectroscopic experiments. The new compound can be considered the acetyl derivative of the biogenetic precursor of other irregular diterpenes isolated from other species belonging to the family Apiaceae.

PharmacologyApiaceaebiology010405 organic chemistryChemistryPlant ScienceGeneral Medicinebiology.organism_classification01 natural sciencesTerpenoid0104 chemical sciences010404 medicinal & biomolecular chemistryComplementary and alternative medicineDrug DiscoveryBotanyMagydaris
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Characterization and antimicrobial activity of the volatile components of the flowers of Magydaris tomentosa (Desf.) DC. collected in Sicily and Alge…

2014

The essential oils of the flowers of Magydaris tomentosa (Desf.) DC. (Apiaceae) collected in Sicily (MSi) and Algeria (MAl), respectively, were obtained by hydrodistillation, and their compositions were analysed. The analyses allowed the identification and quantification of 23 components in MSi and 60 compounds in MAl, respectively, showing a very different profile in the composition of the two populations. The main components of MSi were cembrene (28.2%), α-springene (17.5%) and β-springene (14.8%), also present in MAl but in lesser amount (0.4%, 1.8% and 0.9%, respectively), whereas the principal constituents of MAl were (E)-nerolidol (35.4%), α-costol (13.3%) and β-costol (6.8%). Both MS…

β-springeneFlowersMicrobial Sensitivity TestsPlant ScienceBiochemistryMagydaris tomentosaGas Chromatography-Mass Spectrometryessential oilAnalytical ChemistryAnti-Infective Agentsα\-springeneStaphylococcus epidermidisparasitic diseasesOils VolatileMagydarisSicilyApiaceaeantimicrobial activitybiologyTraditional medicineOrganic ChemistrySettore CHIM/06 - Chimica Organicabiology.organism_classificationAntimicrobialαspringeneAnti-Bacterial AgentsPlant LeavesChemotaxonomyAlgerialipids (amino acids peptides and proteins)Composition (visual arts)DiterpenesAntibacterial activitySesquiterpenesApiaceae
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