Search results for "Malin"

Nemaline myopathy with intranuclear rods--intranuclear rod myopathy.

1997

Among the different nosological forms of nemaline/rod myopathy, one morphological variant is marked by intranuclear rods in addition to sarcoplasmic rods. Such patients fall into two categories: firstly, adults and secondly, young infants suffering from the severe form. Intranuclear rods indicate unfavourable prognosis. Recently, intranuclear rods without sarcoplasmic rods have also been encountered. Intranuclear rods, largely solitary, are often found large in size with the ultrastructural lattice pattern of sarcoplasmic rods and Z-disks. They contain alpha-actinin and actin. The origin of intranuclear rods is still enigmatic. Their presence within nuclei without sarcoplasmic rods points t…

Structural congenital myopathies (excluding nemaline myopathy, myotubular myopathy and desminopathies): 56th European Neuromuscular Centre (ENMC) spo…

1999

Petrogenesis of tourmaline rocks associated with Fe-carbonate-graphite metapelite, metabasite and strata-bound polymetallic sulphide mineralisation, …

2007

Abstract Tourmalinite and tourmaline-rich rocks associated with Fe-carbonate–graphite phyllite, strata-bound polymetallic sulphide deposits, metabasite and marble were studied, for information on the mechanism of tourmaline formation in the pre-Hercynian low-grade metamorphic sequence of the Mandanici Unit in the Peloritani Mountains of Sicily, southern Italy. The major and trace element compositions of the tourmaline rocks suggest the existence of a sedimentary protolith with pre-metamorphic black shale and bedded chert. Boron was interpreted to be accumulated in a restricted sedimentary basin, between platform carbonate formations, with abundant organic matter and Fe–Al–Ti-rich laterite–b…

Die Wirkung von Harmalin auf die Konzentration von Noradrenalin und Adrenalin im Herzen

1959

A single injection of harmaline increases the noradrenaline and adrenaline concentration in the rat heart. The maximum effect is obtained after about 40 min.

Investigation of the Alkaloid Content of Rauwolfia serpentina Roots from Regenerated Plants.

1991

The indole alkaloid content of RAUWOLFIA SERPENTINA roots from regenerated plants (from stem-and root-callus) was compared with the parental stock. Although the total alkaloid content seems to be slightly higher in the roots from regenerated plants, HPLC-analysis of individual alkaloids indicated that the contents of the alkaloids ajmaline ( 1), serpentine ( 2), and reserpine ( 3) are lower than in the roots of the parental stock. The glucoalkaloid raucaffricine ( 4) was identified as a constituent of all samples, thus providing the first evidence for its occurrence in roots of RAUWOLFIA SERPENTINA.

Isolation, Identification, and Chemical Synthesis of 6α-Hydroxyraumacline: A Novel Alkaloid from CultivatedRauwolfia serpentinaCells

1992

From RAUWOLFIA SERPENTINA cells cultivated in the presence of ajmaline ( 2) the new indole alkaloid, 6alpha-hydroxyraumacline ( 1), was isolated. This alkaloid also occurs in significant amounts in the nutrition medium. A simple chemical synthesis of 1 was developed starting from ajmaline ( 2).

Enzymatic formation of the sarpagan-bridge: a key step in the biosynthesis of sarpagine- and ajmaline-type alkaloids.

1995

The glucoalkaloid strictosidine has been converted under cell-free conditions into 10-deoxysarpagine (= normacusine B) in the presence of a crude soluble enzyme extract and microsomal protein isolated from cell suspensions of Rauwolfia serpentina. The enzymatic formation of this alkaloid bearing the C-5/C-16 bond (sarpagan-bridge), which is characteristic for all sarpagine- and ajmaline-type alkaloids, is dependent on NADPH and oxygen. Inhibition studies indicate that for the synthesis of 10-deoxysarpagine a cytochrome P450 dependent monoxygenase is necessary.

Online Civic Identity. Extraction of Features

2013

Abstract The paper presents the importance of study the reactions of the readers and writers of online journals forums from the civic identity point of view, in order to put in evidence categories of publics in the benefit of media, persons and groups. The method is intended to help journalists, PR specialists who are motivated to understand their publics and to target them in a more precise way, in order to upgrade the impact of their online discourse on the people in the community, to know how deep the civic involvement of the people is to the problems of the community.

Releasing rates of inorganic ions in lichens monitored by capillary zone electrophoresis as indicators of atmospheric pollution

2000

Abstract The releasing rates of inorganic ions in lichens when a thallus sample is sonicated under water, were studied. Ramalina farinacea samples taken from two locations exposed to atmospheric pollution sources at Els Ports (Castellon, Spain), and from three control locations, were used. Samples without visual symptoms of injuries were sonicated from 3 to 6 successive 10-min periods while renewing the water layer in between. Experiments with successive 2-min-sonication periods were also performed. The extracts were analysed by capillary zone electrophoresis, and K + , NH 4 + , Na + , Ca 2+ , Mg 2+ , Cl − , SO 4 2− and NO 3 − were detected. The apparently undamaged lichens sampled at locat…

Increased oxidative stress and impaired antioxidant response in Lafora disease.

2014

15 páginas, 10 figuras