Search results for "Mania"

showing 10 items of 710 documents

In vivo and in vitro cytokine profiles and mononuclear cell subsets in sicilian patients with active visceral leishmaniasis

1995

Sera from Sicilian patients with confirmed visceral leishmaniasis (Leishmania donovani infantum) were analysed at the moment of the diagnosis, during the course of the disease and after clinical recovery, for the concentration of IL-10, IFN-gamma, IL-4 and IL-2. The results show high concentrations of IL-10 and IFN-gamma in the sera at the beginning of infection that return to the normal range following successful chemotherapy. By contrast, PBMC stimulated in vitro with Ag and mitogen produced low levels of IL-10 and IFN-gamma when collected at the time of the diagnosis and normal levels when assayed after recovery. IL-2 was undetected in the sera and was significantly reduced in the supern…

MaleCD3medicine.medical_treatmentImmunologyAntigens ProtozoanBiochemistryPeripheral blood mononuclear cellAntigenIn vivomedicineAnimalsHumansImmunology and AllergyMacrophagePhytohemagglutininsSicilyMolecular BiologybiologyHematologymedicine.diseaseStimulation ChemicalRatsVisceral leishmaniasisCytokineCase-Control StudiesImmunologyDisease ProgressionLeukocytes Mononuclearbiology.proteinLeishmaniasis VisceralFemaleCD8Cytokine
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Oral lichenoid drug reaction by lithium in a patient with bipolar disorder

2005

Bipolar disorder (BD) is a psychiatric disease characterized by recurrent and alternated episodes of depression and mania. For the treatment of BD, anticonvulsants drugs as lithium, carbamazepine and oxcarbazepine can be used. These drugs can be associated with potential adverse effects: weight gain, tremors, thyroid abnormalities, and cognitive, gastrointestinal, cardiac or dermatological problems. We describe a case of BD with oral lichenoid drug reaction probably because of the mood stabilizers.

MaleCancer Researchmedicine.medical_specialtyBipolar DisorderLichenoid EruptionsLithium (medication)antipsychotics bipolar disorders drug reaction lichenoid lesions lithium therapyPathology and Forensic Medicinechemistry.chemical_compoundLithium CarbonateAntimanic Agentsmental disordersmedicineHumansBipolar disorderOxcarbazepineAdverse effectbusiness.industryLithium carbonateCarbamazepineMiddle Agedmedicine.diseaseDermatologySurgeryOtorhinolaryngologychemistryLichenoid eruptionPeriodonticsOral Surgerymedicine.symptomMouth DiseasesbusinessManiamedicine.drugJournal of Oral Pathology and Medicine
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Prediction of the mesiodistal size of unerupted canines and premolars for a group of Romanian children: a comparative study

2013

Objectives The aim of the present study was to develop an optimization method of multiple linear regression equation (MLRE), using a genetic algorithm to determine a set of coefficients that minimize the prediction error for the sum of permanent premolars and canine dimensions in a group of young people from a central area of Romania represented by a city called Sibiu. Material and Methods To test the proposed method, we used a multiple linear regression equation derived from the estimation method proposed by Mojers, to which we adjusted regression coefficients using the Breeder genetic algorithm. A total of 92 children were selected with complete permanent teeth with no clinically visible …

MaleCuspidCorrelation coefficientAdolescentDentistryCorrelationPredictive Value of TestsReference ValuesLinear regressionGenetic algorithmStatisticsHumansOdontometryBicuspidTooth UneruptedChildGeneral DentistryMathematicsPermanent teethbusiness.industryRomaniaLinear modelReproducibility of ResultsRegression analysisOriginal ArticlesOrgan SizeGenetic algorithmsDentition mixedlcsh:RK1-715Mesiodistal crown diametersRomanian populationlcsh:DentistryLinear ModelsCalipersFemalebusinessRegression analysisAlgorithms
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Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countrie…

2015

Summary Background Up-to-date evidence about levels and trends in disease and injury incidence, prevalence, and years lived with disability (YLDs) is an essential input into global, regional, and national health policies. In the Global Burden of Disease Study 2013 (GBD 2013), we estimated these quantities for acute and chronic diseases and injuries for 188 countries between 1990 and 2013. Methods Estimates were calculated for disease and injury incidence, prevalence, and YLDs using GBD 2010 methods with some important refinements. Results for incidence of acute disorders and prevalence of chronic disorders are new additions to the analysis. Key improvements include expansion to the cause an…

MaleGerontologyNutrition and DiseaseEpidemiologyyears lived with disability Global burden of disease acute and chronic diseases countriesPrevalenceDiseaseGlobal HealthMedical and Health SciencesConduct disorderOtitis-mediaCost of IllnessResidence CharacteristicsVoeding en ZiekteEpidemiologyPrevalence80 and overGlobal health2.2 Factors relating to the physical environment2.1 Biological and endogenous factorscountriesAetiologyChildAged 80 and overMedicine(all)education.field_of_studyATTENTION-DEFICIT/HYPERACTIVITY DISORDERIncidenceMortality rateIncidence (epidemiology)Pain ResearchNeglected DiseasesAlcohol dependenceGeneral MedicineMiddle AgedGlobal burden of diseaseGlobal Burden of Disease Study 2013 CollaboratorsMental HealthInfectious DiseasesAttention deficit/Hyperactivity disorderBurden of IllnessChild PreschoolAcute DiseaseFemaleLife Sciences & BiomedicineAdultmedicine.medical_specialtyAdolescentGBD 2013Populationacute and chronic diseasesYoung AdultMental-disordersAge DistributionMedicine General & InternalWeightsGeneral & Internal MedicinemedicineHumansLife ScienceDisabled PersonsSex DistributionPreschooleducationDeveloping CountriesVLAGAgedScience & Technologybusiness.industryDeveloped CountriesCutaneous LeishmaniasisInfant NewbornInfantHealth outcomesNewbornmedicine.diseaseComorbidityBrain Disordersyears lived with disabilityGood Health and Well BeingDisease injury incidence prevalence YLDs GBD 2010Chronic DiseaseWounds and Injuriesbusiness2.4 Surveillance and distributionIron-deficiencyDemography
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Knowledge, stigma, health seeking behaviour and its determinants among patients with post kalaazar dermal leishmaniasis, Bihar, India

2018

Background Lesishmaniasis is a neglected tropical disease endemic in Bihar, India. Inappropriate health seeking behaviour of post kala-azar dermal leishmaniasis (PKDL) patients may increase the disease duration, severity and transmissibility. Simultaneously, lack of knowledge and perceived stigma may also increase the length of delay in receiving treatment. This ultimately effects the kala-azar elimination program. Methods A cross sectional study was conducted in 120 confirmed PKDL patients, aged 18 years and older. Data related to knowledge and health seeking behaviour was collected by a pre-tested questionnaire. EMIC stigma scale was used for assessing the perceived stigma. Patients were …

MaleHealth Knowledge Attitudes PracticePediatricsTime FactorsSocial stigmaCross-sectional studyHealth Care ProvidersHealth BehaviorSocial Stigmalcsh:MedicineDiseaseDisease VectorsPathology and Laboratory Medicine0302 clinical medicineInformed consentZoonosesMedicine and Health SciencesMedicinePublic and Occupational Health030212 general & internal medicineYoung adultlcsh:ScienceLeishmaniasisMultidisciplinaryMiddle AgedInfectious DiseasesLeishmaniasis VisceralFemaleBehavioral and Social Aspects of HealthResearch ArticleNeglected Tropical DiseasesAdultmedicine.medical_specialtyAdolescentPatients030231 tropical medicineAntiprotozoal AgentsIndiaLeishmaniasis CutaneousStigma (botany)DermatologySkin DiseasesYoung AdultKala-Azar03 medical and health sciencesSigns and SymptomsDiagnostic Medicineparasitic diseasesParasitic DiseasesHumansAgedProtozoan Infectionsbusiness.industrylcsh:RBiology and Life SciencesTropical diseasePatient Acceptance of Health CareTropical Diseasesmedicine.diseaseInsect VectorsSand FliesHealth CareSpecies InteractionsCross-Sectional StudiesLesionslcsh:QbusinessLeishmania donovaniPatient educationPLOS ONE
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Perceived effectiveness, restrictiveness and compliance with containment measures against the Covid-19 pandemic: an international comparative study i…

2021

National governments took action to delay the transmission of the coronavirus (SARS-CoV-2) by implementing different containment measures. We developed an online survey that included 44 different containment measures. We aimed to assess how effective citizens perceive these measures, which measures are perceived as violation of citizens’ personal freedoms, which opinions and demographic factors have an effect on compliance with the measures, and what governments can do to most effectively improve citizens’ compliance. The survey was disseminated in 11 countries: UK, Belgium, Netherlands, Bulgaria, Czech Republic, Finland, India, Latvia, Poland, Romania, and Sweden. We acquired 9543 unique r…

MaleHealth Toxicology and Mutagenesiscoronaviruscontainment measureslcsh:MedicineEffectivenessrestrictiveness0302 clinical medicineBelgiumPandemicHuman rights030212 general & internal medicineBulgariaFinlandhealth care economics and organizationsmedia_commonCzech RepublicNetherlandsHuman rightsPublic economicsHälsovetenskaperproportionality principle3. Good healthpublic health measuresCovid-19medicine.medical_specialtyCoronavirus disease 2019 (COVID-19)media_common.quotation_subjecteffectivenessIndiahuman rightscomplianceArticleCompliance (psychology)03 medical and health sciencesHealth SciencesmedicineHumansFinancial compensationProportionality principleRestrictivenessPandemicsSwedenPandemicRomaniaSARS-CoV-2Public healthpandemiclcsh:RPublic Health Environmental and Occupational HealthCOVID-19LatviaCoronavirusContainmentBusinessPoland030217 neurology & neurosurgery
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Bioaccumulation of persistent organic pollutants in the gonads of Barbus barbus (Linnaeus, 1758)

2020

Maps with grey or even white spaces are still present in spite of the fact that persistent organic pollutants (POPs) are at the forefront of research in aquatic toxicology and environmental safety. This is also the case for the Mureș River basin. The intensive use of industrial substances such as polychlorinated biphenyls (PCBs) and pesticides such as organochlorine compounds (OCPs) has caused global contamination of the aquatic environment. In our study we have found very high concentrations of both PCBs (2110-169,000 ng/g lipid weight ΣPCB, 1950-166,000 ng/g lipid weight ΣPCB7) and OCPs (1130-7830 ng/g lipid weight ΣDDT, 47.6-2790 ng/g lipid weight ΣHCH, 5.53-35.6 ng/g lipid weight ΣChlor…

MaleHealth Toxicology and Mutagenesismedia_common.quotation_subjectCyprinidae0211 other engineering and technologies02 engineering and technology010501 environmental sciences01 natural sciencesAquatic toxicologyRiversEnvironmental safetyHydrocarbons ChlorinatedAnimalsPesticidesGonads0105 earth and related environmental sciencesmedia_commonPollutant021110 strategic defence & security studiesbiologyRomaniaChemistryPublic Health Environmental and Occupational HealthGeneral MedicineContaminationPesticideBarbus barbusbiology.organism_classificationBioaccumulationPolychlorinated BiphenylsPollutionEnvironmental chemistryBioaccumulationFemaleReproductionWater Pollutants ChemicalEnvironmental MonitoringEcotoxicology and Environmental Safety
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The genus Tuponia Reuter, 1875 in Romania, with two new synonymies (Heteroptera: Miridae)

2021

Based on recently collected material and on type specimens deposited in the collections of Muzeul de Istorie Naturală “Grigore Antipa”, Bucharest, Romania, and of the Zoologische Museum, Universität Hamburg, Germany, the following new synonymies are proposed: Tuponia (Chlorotuponia) prasina (Fieber, 1864) = Tuponia (Chlorotuponia) linnavuorii Wagner, 1961, syn. n.; Tuponia (Tuponia) montandoni Reuter, 1899 = Tuponia (Tuponia) macedonica Wagner, 1957, syn. n. Lectotype and paralectotype are designated for Tuponia (Tuponia) montandoni Reuter, 1899. Tuponia (Chlorotuponia) hippophaes (Fieber, 1861), Tuponia (Tuponia) arcufera Reuter, 1879 and Tuponia (Tuponia) elegans (Jakovlev, 1867) are reco…

MaleInsectaArthropodaMale genitaliaIdentification keyZoologyPhylinaeHeteropteraHemipteraType (biology)GenusAnimalsAnimaliaEcology Evolution Behavior and SystematicsTaxonomybiologyRomaniaHeteropteraAnimal StructuresOrgan SizeBiodiversitybiology.organism_classificationMiridaeSynonym (taxonomy)Animal Science and ZoologyMiridaeAnimal DistributionZootaxa
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A 6 day course of liposomal amphotericin B in the treatment of infantile visceral leishmaniasis: the Italian experience

2004

Objectives To evaluate in a retrospective analysis the efficacy and safety of a 6 day course of liposomal amphotericin B (L-AmB) in infantile cases of Mediterranean visceral leishmaniasis (VL) diagnosed over a 10 year period in Italy. Patients and methods Patients included were diagnosed as having VL consecutively admitted from December 1992 to December 2001 at four main referral children's hospitals in Italy and treated with six intravenous doses of 3 mg/kg L-AmB given on days 1-5 and 10 (a total dose of 18 mg/kg). Demographic data, nutritional status, underlying diseases, clinical and laboratory findings, and therapy outcome were considered. Results A total of 164 HIV-negative children (m…

MaleMicrobiology (medical)medicine.medical_specialtyAdolescentFeverAntiprotozoal AgentsFluorescent Antibody TechniqueNutritional Statusitaly; leishmania infantum; therapyBone MarrowRecurrenceAmphotericin BInternal medicineAmphotericin BmedicineHumansPharmacology (medical)ChildAdverse effectleishmaniasisRetrospective StudiesPharmacologyDrug Carriersbiologybusiness.industryInfantRetrospective cohort studyLeishmaniasismedicine.diseasebiology.organism_classificationSurgeryRegimenTreatment OutcomeInfectious DiseasesVisceral leishmaniasisItalyEl NiñoChild PreschoolLiposomesLeishmaniasis VisceralFemaleLeishmania infantumbusinessmedicine.drug
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Leishmaniasis, autoimmune rheumatic disease, and anti–tumor necrosis factor therapy, Europe.

2009

We report 2 cases of leishmaniasis in patients with autoimmune rheumatic diseases in Greece. To assess trends in leishmaniasis reporting in this patient population, we searched the literature for similar reports from Europe. Reports increased during 2004–2008, especially for patients treated with anti–tumor necrosis factor agents.

MaleNecrosisgenetic structuresEpidemiologymedicine.medical_treatmentAnti-Inflammatory Agentslcsh:MedicineAnti-TNF0302 clinical medicineRisk FactorsMedicine030212 general & internal medicinerheumatic diseaseLeishmaniasisLeishmaniaimmunosuppressionbiologyDispatchAntibodies MonoclonalRheumatic diseaseImmunosuppressionMiddle Aged3. Good healthEuropeTreatment OutcomeInfectious DiseasesRheumatic feverFemaleTumor necrosis factor alphaImmunotherapymedicine.symptomMicrobiology (medical)medicine.medical_specialtytumor necrosis factor030231 tropical medicineletterparasiteslcsh:Infectious and parasitic diseases03 medical and health sciencesRheumatic DiseasesAnimalsHumansautoimmune diseaseslcsh:RC109-216Letters to the EditorAged030203 arthritis & rheumatologyTumor Necrosis Factor-alphabusiness.industryscreeninglcsh:RLeishmaniasisImmunotherapyLeishmaniabiology.organism_classificationmedicine.diseaseDermatologyInfliximabAnti-Tumor Necrosis Factor TherapyImmunologysense organsbusinessEmerging Infectious Diseases
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