Search results for "Mediator"
showing 10 items of 339 documents
Four News Media Roles Shaping Agenda-building Processes
2019
This chapter identifies, defines and explores four news media roles of conduit, facilitator, mediator and political actor through which the media participate with corporate, social and political actors in agenda-building processes. The framework of the media’s four agenda-building roles sheds light on how the news media perform their various roles as well as how other actors, such as organizations and media audiences, are able to mobilize the media performing these roles. This framework helps explain how and why media roles affect the way actors are able to influence the media agenda with the intention of shaping the public agenda. peerReviewed
The Life Cycle of the Mu-Opioid Receptor
2020
Opioid receptors (ORs) are undisputed targets for the treatment of pain. Unfortunately, targeting these receptors therapeutically poses significant challenges including addiction, dependence, tolerance, and the appearance of side effects, such as respiratory depression and constipation. Moreover, misuse of prescription and illicit narcotics has resulted in the current opioid crisis. The mu-opioid receptor (MOR) is the cellular mediator of the effects of most commonly used opioids, and is a prototypical G protein-coupled receptor (GPCR) where new pharmacological, signalling and cell biology concepts have been coined. This review summarises the knowledge of the life cycle of this therapeutic …
"Fuelling" Cognitive Judgments: Worry as a Mediator Between Risk Perceptions and Intentions to Quit Smoking
2012
Published version of an article in the journal: Europe's Journal of Psychology. Also available from the publisher at: http://dx.doi.org/10.5964/ejop.v8i3.479 Open access. The aim of the present study was to assess the importance of cognitive and affective risk perceptions along with measures of self-prediction of future smoking status and confidence in one’s ability to quit on intentions to quit smoking. Additionally, the purpose was to explore the mediating effect of worry on the relation between risk perception and quitting smoking intentions. The data consist of 415 participants defined as daily and “sometimes” smokers who were interviewed by telephone. The results showed significant dir…
Identity and socio-educational responsibilities of the educational mediator and the intercultural mediator: towards a clarification of functions
2012
El presente artículo reconoce que, ante la creciente presencia en escenarios socioeducativos de la figura profesional del mediador en los dos ámbitos principales relacionados con la educación (el escolar y el intercultural), deben identificarse los rasgos idiosincrásicos de cada uno de ellos, lo que no es óbice para reconocer cómo, a pesar de que existen, en efecto, diferencias en la definición de estos dos modelos de mediación, se evidencian aspectos coincidentes que los vinculan a un tronco común: las competencias y responsabilidades socioeducativas que adquieren cada uno de ellos. Las autoras del artículo aplican la metodología comparada para demostrar ambas realidades compatibles en las…
Mediación y jurisdicción voluntaria en el marco de la modernización de la justicia. una aproximación a la legislación española
2013
ResumenLa máxima legal Justicia retrasada es justicia denegada, es hoy sin embargo una realidad. Las personas demandan agilidad y requieren de una solución medianamente pronta y cercana a sus intereses, no es acertado que en un mundo dominado por la tecnología, la burocracia jurídica y administrativa en torno a la impartición de la justicia mantenga un ritmo lento. A nivel internacional se buscan fórmulas de solución pronta y económica de los conflictos, en este camino se impulsan entre varias vías jurídicas, por una parte la jurisdicción voluntaria, por otra parte la mediación, en ambas se trata de agilizar procedimientos, sin embargo la naturaleza jurídica de cada una de ellas es diferent…
Tumors of the labial mucosa: a retrospective study of 1045 biopsies
2020
Background To investigate the relative frequency of localized mucosal swellings of the upper and lower labial mucosa, the clinical-pathological diagnosis agreement and whether patient’s age and gender and tumor’s site and size may raise the suspicion of neoplasm. Material and Methods Retrospective analysis was performed on upper or lower labial mucosal tumors, histopathologically diagnosed between 2009-2018. The diagnostic categories developmental/reactive tumors, benign and malignant neoplasms were associated with patient’s age and gender and tumor’s site and size; clinical-pathological diagnosis agreement was, also, evaluated. Results Overall, 1000 (95.7%) developmental/reactive tumors, 3…
Models for non-alcoholic fatty liver disease: a link with vascular risk.
2008
Non alcoholic fatty liver disease (NAFLD) is often part of the metabolic syndrome which includes central obesity, dyslipidaemia, insulin resistance/type 2 diabetes mellitus and hypertension. In turn, NAFLD may be associated with an increased vascular risk. Several experimental models which express histological steatosis or steatohepatitis with fibrosis have been described. This review identifies those models of NAFLD with features of vascular risk.
Effects of alcohol-free beer on lipid profile and parameters of oxidative stress and inflammation in elderly women
2009
We assessed the influence of alcohol-free beer on factors implicated in atherosclerosis, such as lipid profile, oxidative stress parameters, and proinflammatory cytokines, in postmenopausal women, a population particularly at risk for atherosclerotic disease.The study was carried out in 29 nuns, 58 to 73 y old, who live in a convent with a disciplined, regular, and homogeneous lifestyle. The nuns maintained their habits and diet routine, but their meals were supplemented with 500 mL/d of alcohol-free beer (0.0%) divided into two doses over a 45-d period. Lipid profile, inflammatory markers such as C-reactive protein, interleukins 1 and 6, and tumor necrosis factor-alpha, and parameters of o…
Inflammatory mediators as biomarkers in brain disorders.
2013
Neurodegenerative diseases such as Alzheimer, Parkinson, amyotrophic lateral sclerosis, and Huntington are incurable and debilitating conditions that result in progressive death of the neurons. The definite diagnosis of a neurodegenerative disorder is disadvantaged by the difficulty in obtaining biopsies and thereby to validate the clinical diagnosis with pathological results. Biomarkers are valuable indicators for detecting different phases of a disease such as prevention, early onset, treatment, progression, and monitoring the effect of pharmacological responses to a therapeutic intervention. Inflammation occurs in neurodegenerative diseases, and identification and validation of molecules…
Inflammation and Aortic Stiffness: An Individual Participant Data Meta‐Analysis in Patients With Inflammatory Bowel Disease
2017
Background The recent finding that aortic pulse wave velocity ( aPWV ) is increased in patients with inflammatory bowel disease may explain why the cardiovascular risk is increased despite the low prevalence of traditional cardiovascular risk factors. We aimed to test whether inflammation is associated with aortic stiffening in this setting after adjustment for major confounders and to perform subgroup analyses. Methods and Results A systematic literature search for aPWV in inflammatory bowel disease was performed using PubMed, Scopus, Web of Science, and Google Scholar databases (last accessed May 7, 2017). Inclusion criterion was peer‐reviewed publications on clinical studies reporting o…