Search results for "Memory"
showing 10 items of 2004 documents
RNA Transfer by Electroporation into Mature Dendritic Cells Leading to Reactivation of Effector-Memory Cytotoxic T Lymphocytes: A Quantitative Analys…
2005
Previous studies have analyzed transfer of RNA-encoded tumor-associated antigens (TAAs) into immature dendritic cells (DCs) because of their exceptional ability to internalize antigens. Concerns have been raised regarding the use of immature DCs in clinical studies because of their capacity to tolerize T cells. Therefore, we focused on optimizing RNA transfer into mature DCs using the method of electroporation and obtained high protein expression in 90% of mature DCs. Particular emphasis was placed on quantifying RNA transfer. Reconstitution of peptide-MHC (pMHC) ligands on RNA-pulsed DCs was measured with the help of effector-memory cytotoxic T lymphocytes (CTLs) specific for the melanoma-…
La oscura memoria: cine negro y brechas fantásticas en Enterrar a los muertos (2005) y Las serpientes ciegas (2008) [Una contraposición]
2021
La literatura en torno a la memoria es uno de los puntales de la narrativa hispánica reciente. Lo que este artículo pretende es adentrarse en una de sus áreas más inexploradas (las purgas estalinistas en España durante la Guerra Civil) a través del análisis y la confrontación de dos obras tan reconocidas como heterodoxas: la novela Enterrar a los muertos, de Ignacio Martínez de Pisón, y el cómic Las serpientes ciegas, de Felipe Hernández Cava y Bartolomé Seguí. La pasarela que comunica ambos textos es la estética de cine negro que ambienta el cómic y que –como intentaremos demostrar– modula la tensión de la novela. El final del camino lo marca el empleo de lo fantástico por parte de Cava y …
Assembly of Polycomb complexes and silencing mechanisms
2003
Polycomb complexes assemble at their target sites and silence neighboring genes when these are not actively transcribed. The action of these complexes and of Trithorax complexes bound to the Polycomb Response Element establish alternative silent or derepressed states that are remembered through cell division and maintained for the rest of development. Recent results that may help explain the properties of these states are reviewed.
Body image and depression
2021
Abstract This chapter presents research findings on body image in depression sufferers. Body image is here considered to consist of three elements: image properties, body-self, and body memory. In depressed patients, the body image has characteristics typical to the disorder, influencing how they relate to themselves and their environment. Typical to the body image of depression sufferers experience low energy, discomfort in the body during social interaction, and a tendency to distance oneself from sensing the body. While having this fragmented connection to their own bodies, patients tend to ruminate on how others perceive them. Compared with standard care, dance movement therapy group tr…
Event-based encoding from digital magnetic compass and ultrasonic distance sensor for navigation in mobile systems
2016
Event-based encoding reduces the amount of generated data while keeping relevant information in the measured magnitude. While this encoding is mostly associated with spiking neuromorphic systems, it can be used in a broad spectrum of tasks. The extension of event-based data representation to other sensors would provide advantages related to bandwidth reduction, lower computing requirements, increased processing speed and data processing. This work describes two event-based encoding procedures (magnitude-event and rate-event) for two sensors widely used in industry, especially for navigation in mobile systems: digital magnetic compass and ultrasonic distance sensor. Encoded data meet Address…
Atmiņā esošu datubāžu funkcionalitātes un veiktspējas analīze
2016
Bakalaura darba “Atmiņā esošu datubāžu funkcionalitātes un veiktspējas analīze” mērķis ir izpētīt atmiņā esošu jeb in-memory datubāžu tehnoloģiju, kas pēc būtības ir datubāzes satura glabāšana operatīvajā atmiņā. Šī tehnoloģija pašos pamatos atšķiras no tradicionālās disku bāzētas datubāžu tehnoloģijas un dod lielu veiktspējas uzlabojumu. Darba uzdevumi ir izpētīt atmiņā esošu datubāžu darbību un pieejamo mūsdienu risinājumu funkcionalitāti, kā arī izveidot TPC-C etalonuzdevumu, lai varētu novērtēt veiktspēju. Rezultātā šī tehnoloģija tika izpētīta un tika izstrādāts etalonuzdevums uz Microsoft Hekaton risinājuma pamata, kas parāda biznesa caurlaides spēju pie dažāda lietotāju skaita ar dis…
Mašīnmācīšanās pielietojums sporta notikumu prognozēšanā
2017
Dažādu notikumu prognozēšana cilvēcei ir vienmēr bijusi aktuāla. Mūsdienās ir attīstījušās tehnoloģijas, lai to būtu iespējams paveikt balstoties uz pagātnes datiem. Darbā tiek apskatīta sporta notikumu prognozēšana, konkrēti futbola maču iznākumi. Tiek apskatītas vairākas mašīnmācīšanās metodes, kas būtu piemērotākās šī uzdevuma veikšanai. Tiek realizēti un optimizēti divi multi-slāņu perceptrona tīkli un viens vairākkārtējā neironu tīkla, konkrēti LSTM algoritms. Ar tiem tiek veikta simulācija izmantojot reālus datus. Vienā no simulācijām tiek sasniegts pozitīvs rezultāts, sezonas laikā algoritms gūst 65% peļņu.
The effects of associative and semantic priming in the lexical decision task.
2001
Four lexical decision experiments were conducted to examine under which conditions automatic semantic priming effects can be obtained. Experiments 1 and 2 analyzed associative/semantic effects at several very short stimulus-onset asynchronies (SOAs), whereas Experiments 3 and 4 used a single-presentation paradigm at two response-stimulus intervals (RSIs). Experiment 1 tested associatively related pairs from three semantic categories (synonyms, antonyms, and category coordinates). The results showed reliable associative priming effects at all SOAs. In addition, the correlation between associative strength and magnitude of priming was significant only at the shortest SOA (66 ms). When prime-t…
Probabilistic Logic under Coherence‚ Model−Theoretic Probabilistic Logic‚ and Default Reasoning in System P
2016
We study probabilistic logic under the viewpoint of the coherence principle of de Finetti. In detail, we explore how probabilistic reasoning under coherence is related to model-theoretic probabilistic reasoning and to default reasoning in System P. In particular, we show that the notions of g-coherence and of g-coherent entailment can be expressed by combining notions in model-theoretic probabilistic logic with concepts from default reasoning. Moreover, we show that probabilistic reasoning under coherence is a generalization of default reasoning in System P. That is, we provide a new probabilistic semantics for System P, which neither uses infinitesimal probabilities nor atomic bound (or bi…
Conceptual design of the TRACE detector readout using a compact, dead time-less analog memory ASIC
2015
[EN] The new TRacking Array for light Charged particle Ejectiles (TRACE) detector system requires monitorization and sampling of all pulses in a large number of channels with very strict space and power consumption restrictions for the front-end electronics and cabling. Its readout system is to be based on analog memory ASICs with 64 channels each that sample a View the MathML source window of the waveform of any valid pulses at 200 MHz while discarding any other signals and are read out at 50 MHz with external ADC digitization. For this purpose, a new, compact analog memory architecture is described that allows pulse capture with zero dead time in any channel while vastly reducing the tota…