Search results for "Mental disorders"
showing 10 items of 1528 documents
Stick around: Cell–Cell Adhesion Molecules during Neocortical Development
2021
The neocortex is an exquisitely organized structure achieved through complex cellular processes from the generation of neural cells to their integration into cortical circuits after complex migration processes. During this long journey, neural cells need to establish and release adhesive interactions through cell surface receptors known as cell adhesion molecules (CAMs). Several types of CAMs have been described regulating different aspects of neurodevelopment. Whereas some of them mediate interactions with the extracellular matrix, others allow contact with additional cells. In this review, we will focus on the role of two important families of cell–cell adhesion molecules (C-CAMs), classi…
Cranio-Facial Characteristics in Children with Autism Spectrum Disorders (ASD)
2019
Background: Cranio-facial anomalies frequently occur in neurodevelopmental disorders because both face and brain are derived from neuroectoderm. The identification of differences in the facial phenotype of children with Autism Spectrum Disorders (ASD) may reflect alterations in embryologic brain development in children with ASD. Methods: we evaluated 33 caucasian children with ASD using a 2D computerized photogrammetry. Anthropometric euclidean measurements and landmarks located on the soft tissue of the face and head, were based on five cranio-facial indexes. Relationships between anthropometric z-scores and participant characteristics (i.e., age, Global IQ, severity of autistic symptoms m…
Reproducibility of Brain Responses: High for Speech Perception, Low for Reading Difficulties
2019
Neuroscience findings have recently received critique on the lack of replications. To examine the reproducibility of brain indices of speech sound discrimination and their role in dyslexia, a specific reading difficulty, brain event-related potentials using EEG were measured using the same cross-linguistic passive oddball paradigm in about 200 dyslexics and 200 typically reading 8–12-year-old children from four countries with different native languages. Brain responses indexing speech and non-speech sound discrimination were extremely reproducible, supporting the validity and reliability of cognitive neuroscience methods. Significant differences between typical and dyslexic readers were fou…
School achievement in adolescence and the risk of mental disorders in early adulthood: a Finnish nationwide register study
2023
AbstractSchool grades in adolescence have been linked to later psychiatric outcomes, but large-scale nationwide studies across the spectrum of mental disorders are scarce. In the present study, we examined the risk of a wide array of mental disorders in adulthood, as well as the risk of comorbidity, associated with school achievement in adolescence. We used population-based cohort data comprising all individuals born in Finland over the period 1980–2000 (N = 1,070,880) who were followed from age 15 or 16 until a diagnosis of mental disorder, emigration, death, or December 2017, whichever came first. Final grade average from comprehensive school was the exposure, and the first diagnosed ment…
The Role of Teacher Closeness in Emotions and Achievement for Adolescents With and Without Learning Difficulties
2022
Student–teacher relationships are crucial for adolescents’ adjustment in the school context. The aim of the present study was to examine the role of teacher closeness in academic emotions and achievement among adolescents with and without learning difficulties during the first year in lower secondary school. Students’ learning difficulties (LDs) were identified based on tested reading and math skills. In addition, students evaluated their teacher relationships and rated academic emotions in literacy and math domains. The results indicated that higher teacher closeness was related to increasing positive emotions and increasing literacy achievement during seventh grade, whereas lower levels …
The Birth of Orientalism by App, Urs Review by: Pekka Korhonen
2012
A review of the book "The Birth of Orientalism," part of the Encounters With Asia Series, by Urs App, is presented. nonPeerReviewed
Teacher's attitudes towards inclusion and the inclusion of students with emotional and behavioural disorders
2016
Inclusion is both a symbolic and a practically meaningful process inextricably inter-twined with equity, social and educational participation. Teachers are a fundamental part of this process. Therefore, their attitudes carry a dynamic, which, in turn can be linked to educational success and inclusive implementation. Students with emotional and behavioural disorders constitute a challenging and vulnerable group of students, often excluded from the educational setting, with severe academic and social consequences. The main objective of the current study was to explore teachers’ attitudes to-wards the inclusion of students with emotional and behavioural disorders, in primary and secondary educ…
Personality Profile in Orthorexia Nervosa and Healthy Orthorexia
2021
Little is known about orthorexia in both its pathological (orthorexia nervosa, OrNe) and adaptive (healthy orthorexia, HeOr) forms. To date, few studies have been carried out to analyze the personality profile associated with orthorexia, and the results have been contradictory. The aim of the present study was to explore the characteristic pathological personality traits associated with OrNe and HeOr. A total of 297 participants (Mage= 30.8 years; 94.6% women) from the general population completed the Teruel Orthorexia Scale (TOS) and Personality Inventory for DSM-5-Short Form (PID-5-SF) questionnaires. Results showed significant low-medium correlations between OrNe and the four personality…
Work Ability of Finnish Physical Education Teachers
2015
Background: In the physical education (PE) teachers’ profession, physical tasks comprise a large part of their job. They identify their health as good, and they are satisfied with their job. Nevertheless, the work ability of PE teachers may be decrease. Purpose: The purpose of this paper is to explore the work ability of Finnish PE teachers. What disorders or physical problems do PE teachers experience as a result of their job, and how do they affect job satisfaction? Are there differences between men and women or older and younger teachers? Key findings: Of the Finnish PE teachers (N=655), 31% reported that they had at least one disease or disorder that hindered their work ability. The mos…
Disentangling the Amyloid Pathways: A Mechanistic Approach to Etiology
2020
Amyloids are fibrillar protein aggregates associated with diseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD), type II diabetes and Creutzfeldt–Jakob disease. The process of amyloid polymerization involves three pathological protein transformations; from natively folded conformation to the cross-β conformation, from biophysically soluble to insoluble, and from biologically functional to non-functional. While amyloids share a similar cross-β conformation, the biophysical transformation can either take place spontaneously via a homogeneous nucleation mechanism (HON) or catalytically on an exogenous surface via a heterogeneous nucleation mechanism (HEN). Here, we postulate that…