Search results for "MerA"

showing 10 items of 3426 documents

Vapor–liquid equilibria in the ternary system dipropyl ether+1-propanol+1-pentanol and the binary systems dipropyl ether+1-pentanol, 1-propanol+1-pen…

2006

Abstract Consistent vapor–liquid equilibrium (VLE) data at 101.3 kPa have been determined for the ternary system dipropyl ether (DPE) + 1-propanol (PA) + 1-pentanol and two constituent binary systems: DPE + 1-pentanol and PA + 1-pentanol. The DPE + 1-pentanol system shows positive deviations from ideal behaviour and PA + 1-pentanol system exhibits no deviation from ideal behaviour. The activity coefficients and the boiling points were correlated with their compositions by the Wilson, NRTL, UNIQUAC and Wisniak–Tamir equations. It is shown that the models allow a very good prediction of the phase equilibria of the ternary system using the pertinent parameters of the binary systems. 1-Pentanol…

Activity coefficientUNIQUACTernary numeral systemGeneral Chemical EngineeringGeneral Physics and AstronomyThermodynamicsPropanolchemistry.chemical_compoundchemistryAzeotropeNon-random two-liquid modelExtractive distillationBinary systemPhysical and Theoretical ChemistryFluid Phase Equilibria
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Phase equilibria in the systems 3-methylpentane + methylcyclohexane, diisopropyl ether + methylcyclohexane and 3-methylpentane + diisopropyl ether + …

2002

Abstract Consistent vapor–liquid equilibria (VLE) at 101.3 kPa has been determined for the ternary system 3-methylpentane+diisopropyl ether (DIPE)+methylcyclohexane and the binary subsystems 3-methylpentane+methylcyclohexane and DIPE+methylcyclohexane in the temperature range from 336 to 374 K. According to the experimental results, the systems exhibit slight positive deviation from ideal behavior and no azeotrope is present. The VLE data have been correlated with the composition using the Wilson, UNIQUAC and NRTL relations. These models allow good prediction of the VLE properties of the ternary system from those of the pertinent binary subsystems.

Activity coefficientUNIQUACTernary numeral systemGeneral Chemical EngineeringGeneral Physics and AstronomyThermodynamicschemistry.chemical_compoundchemistryAzeotropeNon-random two-liquid modelDiisopropyl etherPhysical and Theoretical ChemistryMethylcyclohexane3-MethylpentaneFluid Phase Equilibria
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Vapor–liquid equilibria in the ternary system isobutyl alcohol+isobutyl acetate+butyl propionate and the binary systems isobutyl alcohol+butyl propio…

2005

Abstract Consistent vapor–liquid equilibrium (VLE) data at 101.3 kPa have been determined for the ternary system isobutyl alcohol (IBA) + isobutyl acetate (IBAc) + butyl propionate (BUP) and two constituent binary systems: IBA + BUP and IBAc + BUP. The IBA + BUP system show lightly positive deviation from Raoult's law and IBAc + BUP system exhibits no deviation from ideal behaviour. The activity coefficients of the solutions were correlated with its composition by the Wilson, NRTL, UNIQUAC models. The ternary system is very well predicted from binary interaction parameters. BUP eliminates the IBA–IBAc binary azeotrope. The change of phase equilibria behaviour is significant therefore this s…

Activity coefficientUNIQUACTernary numeral systemIsobutyl acetateChemistryGeneral Chemical EngineeringGeneral Physics and AstronomyThermodynamicschemistry.chemical_compoundAzeotropeNon-random two-liquid modelOrganic chemistryBinary systemPhysical and Theoretical ChemistryUNIFACFluid Phase Equilibria
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Isobaric Vapor−Liquid Equilibria for Binary and Ternary Mixtures of Dipropyl Ether, 1-Propyl Alcohol, and Butyl Propionate

2006

Consistent vapor−liquid equilibrium (VLE) data at 101.3 kPa have been determined for the ternary system dipropyl ether + 1-propyl alcohol + butyl propionate and two constituent binary systems:  dipropyl ether + butyl propionate and 1-propyl alcohol + butyl propionate. The dipropyl ether + butyl propionate system exhibits ideal behavior, and the 1-propyl alcohol + butyl propionate system shows positive deviations from Raoult's law. No additional azeotropes are present. The activity coefficients of the solutions were correlated with its composition by the Wilson, NRTL, and UNIQUAC models. The ternary system is well-predicted from binary interaction parameters. Butyl propionate breaks the dipr…

Activity coefficientchemistry.chemical_classificationUNIQUACTernary numeral systemGeneral Chemical EngineeringRaoult's lawEtherGeneral ChemistryMedicinal chemistrychemistry.chemical_compoundchemistryAzeotropeNon-random two-liquid modelPropionateOrganic chemistryJournal of Chemical & Engineering Data
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1-Ethyl-3-methylimidazolium Dicyanamide as a Very Efficient Entrainer for the Extractive Distillation of the Acetone + Methanol System

2012

Isobaric vapor–liquid equilibria (VLE) for the ternary system acetone + methanol +1-ethyl-3-methylimidazolium dicyanamide ([emim][DCA]) as well as the two solvent + IL binary systems have been obtained at 100 kPa using a recirculating still. The addition of [emim][DCA] to the solvent mixture produced a salting-out effect greater than that produced by other ionic liquids, showing that this ionic liquid is, until now, the best IL tested as an entrainer for the extractive distillation of the acetone + methanol mixtures, causing the azeotrope to disappear for an ionic liquid mole fraction as low as 0.031, at 100 kPa. This behavior can be explained on the basis of the influence of the IL concent…

Activity coefficientchemistry.chemical_compoundTernary numeral systemChemistryGeneral Chemical EngineeringAzeotropeInorganic chemistryIonic liquidAcetoneNon-random two-liquid modelExtractive distillationGeneral ChemistryDicyanamideJournal of Chemical & Engineering Data
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Phase Equilibria Involved in Extractive Distillation of Dipropyl Ether + 1-Propyl Alcohol Using N,N-Dimethylformamide as Entrainer

2007

Consistent vapor−liquid equilibrium data for the binary and ternary systems dipropyl ether (1) + 1-propyl alcohol (2) + N,N-dimethylformamide (3) are reported at 101.3 kPa. The results indicate that dipropyl ether (1) + N,N-dimethylformamide (3) system exhibits a positive deviation from ideal behavior and that 1-propyl alcohol (2) + N,N-dimethylformamide (3) system deviates negatively from ideality. The activity coefficients of the solutions were correlated by the Wilson, NRTL, and UNIQUAC models. It is shown that these models allow a very good prediction of the phase equilibrium of the ternary system using the pertinent parameters of the binary systems. In addition, the Wisniak−Tamir relat…

Activity coefficientchemistry.chemical_compoundUNIQUACTernary numeral systemChemistryGeneral Chemical EngineeringNon-random two-liquid modelExtractive distillationThermodynamicsAlcoholEtherGeneral ChemistryTernary operationJournal of Chemical & Engineering Data
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Mitochondrial D310 mutations in colorectal adenomas: an early but not causative genetic event during colorectal carcinogenesis.

2008

Somatic mutations of the D310 sequence of the mitochondrial DNA are reported in human cancers, including colorectal cancers (CRC). The presence of these mutations at early or late steps of colorectal carcinogenesis is unknown. Their prevalence increased significantly with the number of cytosines in the D310 sequence of the matched normal tissue (D310 polymorphism), suggesting that this polymorphism could be a risk factor for CRC. The aim of this study was (i) to investigate the prevalence of D310 mutations in 64 colorectal adenomas and 36 liver metastases from 15 CRC patients, (ii) to assess the relation between D310 polymorphism and the risk of colorectal adenoma in a case-control study in…

AdenomaMaleCancer Researchmedicine.medical_specialtyGenotypeColorectal cancerColorectal adenomaMouse model of colorectal and intestinal cancermedicine.disease_causeGastroenterologyDNA MitochondrialPolymerase Chain ReactionGermlineRisk FactorsInternal medicineGenotypemedicineHumansGenetic Predisposition to DiseaseGerm-Line MutationAgedbusiness.industryLiver NeoplasmsCase-control studyCancermedicine.diseasedigestive system diseasesOncologyCase-Control StudiesCancer researchFemalebusinessCarcinogenesisColorectal NeoplasmsInternational journal of cancer
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Machine learning of reverse transcription signatures of variegated polymerases allows mapping and discrimination of methylated purines in limited tra…

2020

AbstractReverse transcription (RT) of RNA templates containing RNA modifications leads to synthesis of cDNA containing information on the modification in the form of misincorporation, arrest, or nucleotide skipping events. A compilation of such events from multiple cDNAs represents an RT-signature that is typical for a given modification, but, as we show here, depends also on the reverse transcriptase enzyme. A comparison of 13 different enzymes revealed a range of RT-signatures, with individual enzymes exhibiting average arrest rates between 20 and 75%, as well as average misincorporation rates between 30 and 75% in the read-through cDNA. Using RT-signatures from individual enzymes to trai…

AdenosineAcademicSubjects/SCI00010Machine learningcomputer.software_genre[SDV.BBM.BM] Life Sciences [q-bio]/Biochemistry Molecular Biology/Molecular biologyMethylationMachine Learning03 medical and health sciences0302 clinical medicineComplementary DNA[SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry Molecular Biology/Genomics [q-bio.GN]GeneticsMolecular BiologyPolymerase030304 developmental biologychemistry.chemical_classification0303 health sciencesOligoribonucleotidesGuanosinebiologybusiness.industryRNA-Directed DNA PolymeraseRNARNA-Directed DNA Polymerase[SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry Molecular Biology/Molecular biologyReverse TranscriptionMethylationReverse transcriptaseEnzymechemistryTransfer RNAbiology.protein[SDV.BBM.GTP] Life Sciences [q-bio]/Biochemistry Molecular Biology/Genomics [q-bio.GN]Artificial intelligenceTranscriptomebusinesscomputer030217 neurology & neurosurgery
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Use of the polymerase chain reaction to demonstrate hepatitis B virus DNA in serum of children with chronic hepatitis B.

1992

The polymerase chain reaction was used to investigate the presence of hepatitis B virus DNA in sera of 61 children with chronic hepatitis B and negative results on dot biot hybridization tests. Our results demonstrate that most chronic carriers of hepatitis B surface antigen in childhood have hepatitis B virus DNA detectable by polymerase chain reaction in their serum and must be considered infectious.

AdolescentHepatitis B virus DNA polymeraseHepatitis B virus DNAmedicine.disease_causePolymerase Chain ReactionVirusHepatitis B virus PRE betalaw.inventionChronic hepatitislawMedicineHumansHepatitis B e AntigensHepatitis B AntibodiesChildPolymerase chain reactionHepatitis B virusbiologybusiness.industryInfantbiology.organism_classificationHepatitis BVirologyHepadnaviridaeChild PreschoolPediatrics Perinatology and Child HealthChronic DiseaseDNA ViralbusinessThe Journal of pediatrics
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Induction of B-cell development in adult mice reveals the ability of bone marrow to produce B-1a cells

2009

AbstractTo study B-cell development from bone marrow (BM), we generated recombination-activating gene 1 (Rag1)–targeted mice lacking mature lymphocytes. B-cell development can be induced in such mice by B cell–specific restoration of a functional Rag1 transcription unit. Follicular and marginal zone B cells populated the spleen when Rag1 expression was permitted. Notably, the peritoneal cavity was dominated by bona fide B-1a cells, as judged by surface markers and functional properties. These BM-derived B-1a cells exhibited a polyclonal VDJ repertoire with substantial N nucleotide insertions. Nevertheless, physiologic frequencies of phosphatidylcholine-specific B cells were detected. Import…

Adoptive cell transfer1303 BiochemistryGenes RAG-1Immunology2720 HematologyB-Lymphocyte SubsetsSpleenBone Marrow CellsEnzyme-Linked Immunosorbent AssayMice Transgenic610 Medicine & healthBiology10263 Institute of Experimental ImmunologyBiochemistryPolymerase Chain ReactionRecombination-activating gene1307 Cell BiologyPeritoneal cavityMicemedicineAnimalsB cellB-Lymphocytes2403 ImmunologyStem CellsCell DifferentiationCell BiologyHematologyMarginal zoneFlow CytometryMolecular biologyAdoptive Transfermedicine.anatomical_structureImmunoglobulin MImmunologybiology.protein570 Life sciences; biologyBone marrow
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